Gene/Protein Characteristic Table for FHC01498

Species
human

Product ID
FHC01498

Corresponding
Flexi Clone PID

Original Clone PID

ORF Sequence
DNA sequence (1068 bp)
Protein sequence (356 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB385071]

Gene
KIBB5244

Symbol
NEUROD1
Alias : BETA2, BHF-1, MODY6, NEUROD, bHLHa3

Description
neurogenic differentiation 1

Original Clone ID
bm02588

Quality control data of this clone

Characterization of the cloned ORF

N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand

Features of the cloned ORF sequence

Length: 1068 bp
Restriction map A Restriction map B
Features of the protein sequence

Length: 356 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
NP_002491 6.5e-106 100.0 neurogenic diff...
Homo sapiens
AAV38535 6.5e-106 100.0 neurogenic diff...
synthetic construct
Q13562 1.1e-105 99.7 Neurogenic diff...
Homo sapiens
XP_003990961 1.1e-105 99.7 neurogenic diff...
Felis catus
BAA11558 1.1e-105 99.7 NeuroD [Homo sa...
Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PF00010 SM00353 PS50888

Result of InterProScan

Search method interpro_ID From To Entry Definition
HMMPfam IPR001092 102 154 PF00010 Basic helix-loop-helix dimerisation region bHLH
HMMSmart IPR001092 107 159 SM00353 Basic helix-loop-helix dimerisation region bHLH
ProfileScan IPR001092 102 154 PS50888 Basic helix-loop-helix dimerisation region bHLH

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_002491 356 125853,601724 100.0 100.0
NP_067014 331 611635 77.8 99.4
NP_006151 382 601725 69.5 98.6
NP_073565 337 611513 71.8 100.0
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