HUGE

Gene/Protein Characteristic Table for KIAA1777

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK07288
Accession No. :	AB055056
Description :	Netrin receptor UNC5D precursor.
HUGO Gene Name :	unc-5 homolog D (C. elegans) (UNC5D)
Clone Name :	fh19201x1
Source :	Human fetal brain

Features of the cloned DNA sequence	Description

Length: 7002 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 4100 bp

Genome contig ID gi51511724f_35421483
PolyA signal sequence
(None)
+----*----+----*----+----*----+----
TCCAATGTCACAAAAGTGAAAATGTTACTAATCTT
Flanking genome sequence
(350241 - 350290)
----+----*----+----*----+----*----+----*----+----*
AGATGTGTTGCATATTTTGTGTTTTTACGTTCCAAACTCTTTCAAAAGCT

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 8 f 35521452 35771722 17 99.4 Perfect prediction

Features of the protein sequence	Description

Length: 954 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
Q6UXZ4	100.0	Netrin receptor...	Homo sapiens
XP_001088208	99.8	netrin receptor...	Macaca mulatta
XP_001494141	99.1	similar to Netr...	Equus caballus
XP_539972	98.3	similar to Netr...	Canis lupus fam...
XP_598235	97.2	similar to netr...	Bos taurus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB011122	9.6e-14	42.3	KIAA0550
AB046788	8.2e-13	33.0	KIAA1568
AB040878	4.3e-11	37.0	KIAA1445
AB111888	1.2e-10	37.9	KIAA2036
AB095949	5.6e-07	50.0	KIAA2029

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR008085 254 267 PR01705 Thrombospondin

IPR008085 272 283 PR01705 Thrombospondin

IPR008085 344 355 PR01705 Thrombospondin

HMMPfam IPR013151 174 234 PF00047 Immunoglobulin

IPR000884 257 306 PF00090 Thrombospondin

IPR000884 313 360 PF00090 Thrombospondin

IPR000906 541 643 PF00791 ZU5

IPR000488 860 937 PF00531 Death

HMMSmart IPR003599 166 251 SM00409 Immunoglobulin subtype

IPR003598 172 239 SM00408 Immunoglobulin subtype 2

IPR000884 256 307 SM00209 Thrombospondin

IPR000884 312 361 SM00209 Thrombospondin

IPR000906 541 643 SM00218 ZU5

IPR000488 848 939 SM00005 Death

ProfileScan IPR007110 167 245 PS50835 Immunoglobulin-like

IPR000884 253 307 PS50092 Thrombospondin

IPR000884 309 361 PS50092 Thrombospondin

IPR000906 541 646 PS51145 ZU5

ScanRegExp IPR000215 484 494 PS00284 Protease inhibitor I4

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR008085	254	267	PR01705	Thrombospondin
IPR008085	272	283	PR01705	Thrombospondin
IPR008085	344	355	PR01705	Thrombospondin
HMMPfam	IPR013151	174	234	PF00047	Immunoglobulin
IPR000884	257	306	PF00090	Thrombospondin
IPR000884	313	360	PF00090	Thrombospondin
IPR000906	541	643	PF00791	ZU5
IPR000488	860	937	PF00531	Death
HMMSmart	IPR003599	166	251	SM00409	Immunoglobulin subtype
IPR003598	172	239	SM00408	Immunoglobulin subtype 2
IPR000884	256	307	SM00209	Thrombospondin
IPR000884	312	361	SM00209	Thrombospondin
IPR000906	541	643	SM00218	ZU5
IPR000488	848	939	SM00005	Death
ProfileScan	IPR007110	167	245	PS50835	Immunoglobulin-like
IPR000884	253	307	PS50092	Thrombospondin
IPR000884	309	361	PS50092	Thrombospondin
IPR000906	541	646	PS51145	ZU5
ScanRegExp	IPR000215	484	494	PS00284	Protease inhibitor I4

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 3 IWGWMILVLVKALSDVCAGTSGF 25 PRIMARY 23

2 383 LYSGLGAAVVAVAVLVIGVTLY 404 PRIMARY 22

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	3	IWGWMILVLVKALSDVCAGTSGF	25	PRIMARY	23
2	383	LYSGLGAAVVAVAVLVIGVTLY	404	PRIMARY	22

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: GACTGGATTAGAGGTGATGGC

Primer_r
: GTGGAAACTACGGAAACGGTG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 8

Experimental conditions

Panel name	: CCR
Primer_f	: GACTGGATTAGAGGTGATGGC
Primer_r	: GTGGAAACTACGGAAACGGTG
PCR product length	: 163 bp
PCR conditions	: 95 °C15 sec64 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	4100 bp
Genome contig ID	gi51511724f_35421483
PolyA signal sequence (None)	+--------+--------+----*----+---- TCCAATGTCACAAAAGTGAAAATGTTACTAATCTT
Flanking genome sequence (350241 - 350290)	----+--------+--------+--------+--------+----* AGATGTGTTGCATATTTTGTGTTTTTACGTTCCAAACTCTTTCAAAAGCT

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	8	f	35521452	35771722	17	99.4	Perfect prediction

Gene/Protein Characteristic Table for KIAA1777

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information