ROUGE

Gene/Protein Characteristic Table for mKIAA4041

Link to : HUGE \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK220170
Description :	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.
Clone Name :	mpf01333 [Vector Info]
Source :	Mouse embryonic tail

Features of the cloned DNA sequence	Description

Length: 6788 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 1770 bp

Genome contig ID gi65543215r_85847574
PolyA signal sequence
(AATAAA,-25)
+----*----+----*----+----*----+----
ATGCATCTATAATAAATTAAGATTTTTGGATTTGT
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
ACCCGTGCTGTGCTGGGTGGTTACTGACCCCACTGTCCTACTCTCTAAGG

Genomic structure deduced by Blast search against draft genome sequences

Features of the protein sequence	Description

Coding region: 3..5015
Length: 1671 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
NP_034016	99.8	cadherin EGF LA...	Mus musculus
O35161	99.8	Cadherin EGF LA...	Mus musculus
XP_001070474	97.1	similar to Cadh...	Rattus norvegicus
XP_600703	83.5	similar to cadh...	Bos taurus
EAW73429	81.0	cadherin, EGF L...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AK220331	1.6e-165	58.5	mKIAA0279
AK129222	2.3e-65	38.2	mKIAA0812
AK122380	6.5e-28	26.0	mKIAA0821
AK129215	7.1e-28	29.5	mKIAA0786
AK122367	1.8e-22	25.8	mKIAA0768

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR001438 11 22 PR00010 Type II EGF-like signature

IPR001438 63 70 PR00010 Type II EGF-like signature

IPR001438 540 550 PR00010 Type II EGF-like signature

HMMPfam IPR006209 15 46 PF00008 EGF-like

IPR006209 55 88 PF00008 EGF-like

IPR012679 118 280 PF00054 Laminin G

IPR012680 118 277 PF02210 Laminin G

IPR006209 301 332 PF00008 EGF-like

IPR012680 367 497 PF02210 Laminin G

IPR006209 524 555 PF00008 EGF-like

IPR006209 559 593 PF00008 EGF-like

IPR002049 651 696 PF00053 Laminin-type EGF-like

IPR001879 700 757 PF02793 Hormone receptor

IPR000203 1055 1108 PF01825 GPS

IPR000832 1113 1356 PF00002 GPCR

HMMSmart IPR001881 11 47 SM00179 EGF-like calcium-binding

IPR006210 14 47 SM00181 Type I EGF

IPR006210 54 89 SM00181 Type I EGF

IPR001881 55 89 SM00179 EGF-like calcium-binding

IPR001791 110 277 SM00282 Laminin G

IPR001881 297 333 SM00179 EGF-like calcium-binding

IPR006210 300 333 SM00181 Type I EGF

IPR001791 359 497 SM00282 Laminin G

IPR001881 519 556 SM00179 EGF-like calcium-binding

IPR006210 523 556 SM00181 Type I EGF

IPR001881 557 594 SM00179 EGF-like calcium-binding

IPR006210 558 594 SM00181 Type I EGF

IPR006210 600 649 SM00181 Type I EGF

IPR006210 650 697 SM00181 Type I EGF

IPR001879 699 761 SM00008 Hormone receptor

IPR000203 1055 1108 SM00303 GPS

ProfileScan IPR001791 90 294 PS50025 Laminin G

IPR001791 337 518 PS50025 Laminin G

NULL 518 684 PS50311 NULL

IPR002049 648 696 PS50027 Laminin-type EGF-like

IPR001879 683 756 PS50227 Hormone receptor

IPR000203 1056 1108 PS50221 GPS

IPR000832 1116 1353 PS50261 GPCR

ScanRegExp IPR006209 35 46 PS00022 EGF-like

IPR000152 312 323 PS00010 Aspartic acid and asparagine hydroxylation site

IPR006209 321 332 PS00022 EGF-like

IPR000152 535 546 PS00010 Aspartic acid and asparagine hydroxylation site

IPR006209 544 555 PS00022 EGF-like

IPR006209 544 559 PS01186 EGF-like

IPR006209 582 593 PS00022 EGF-like

IPR006209 670 681 PS00022 EGF-like

IPR002049 670 703 PS01248 Laminin-type EGF-like

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR001438	11	22	PR00010	Type II EGF-like signature
IPR001438	63	70	PR00010	Type II EGF-like signature
IPR001438	540	550	PR00010	Type II EGF-like signature
HMMPfam	IPR006209	15	46	PF00008	EGF-like
IPR006209	55	88	PF00008	EGF-like
IPR012679	118	280	PF00054	Laminin G
IPR012680	118	277	PF02210	Laminin G
IPR006209	301	332	PF00008	EGF-like
IPR012680	367	497	PF02210	Laminin G
IPR006209	524	555	PF00008	EGF-like
IPR006209	559	593	PF00008	EGF-like
IPR002049	651	696	PF00053	Laminin-type EGF-like
IPR001879	700	757	PF02793	Hormone receptor
IPR000203	1055	1108	PF01825	GPS
IPR000832	1113	1356	PF00002	GPCR
HMMSmart	IPR001881	11	47	SM00179	EGF-like calcium-binding
IPR006210	14	47	SM00181	Type I EGF
IPR006210	54	89	SM00181	Type I EGF
IPR001881	55	89	SM00179	EGF-like calcium-binding
IPR001791	110	277	SM00282	Laminin G
IPR001881	297	333	SM00179	EGF-like calcium-binding
IPR006210	300	333	SM00181	Type I EGF
IPR001791	359	497	SM00282	Laminin G
IPR001881	519	556	SM00179	EGF-like calcium-binding
IPR006210	523	556	SM00181	Type I EGF
IPR001881	557	594	SM00179	EGF-like calcium-binding
IPR006210	558	594	SM00181	Type I EGF
IPR006210	600	649	SM00181	Type I EGF
IPR006210	650	697	SM00181	Type I EGF
IPR001879	699	761	SM00008	Hormone receptor
IPR000203	1055	1108	SM00303	GPS
ProfileScan	IPR001791	90	294	PS50025	Laminin G
IPR001791	337	518	PS50025	Laminin G
NULL	518	684	PS50311	NULL
IPR002049	648	696	PS50027	Laminin-type EGF-like
IPR001879	683	756	PS50227	Hormone receptor
IPR000203	1056	1108	PS50221	GPS
IPR000832	1116	1353	PS50261	GPCR
ScanRegExp	IPR006209	35	46	PS00022	EGF-like
IPR000152	312	323	PS00010	Aspartic acid and asparagine hydroxylation site
IPR006209	321	332	PS00022	EGF-like
IPR000152	535	546	PS00010	Aspartic acid and asparagine hydroxylation site
IPR006209	544	555	PS00022	EGF-like
IPR006209	544	559	PS01186	EGF-like
IPR006209	582	593	PS00022	EGF-like
IPR006209	670	681	PS00022	EGF-like
IPR002049	670	703	PS01248	Laminin-type EGF-like

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 1118 1140 IITYAALSLSLVALLVAFVLLSL

1150 1171 SIHKNLIAALFFSQLIFMVGIN

1176 1198 PFLCTVVAILLHYVSMGTFAWTL

1219 1240 MRFYHVVGWGIPAIVTGLAVGL

1262 1284 SFAGPVGTVIIINTVIFVLSAKV

1300 1322 SMLRTAFLLLLLVTATWLLGLLA

1332 1354 YLFAAFSCLQGIFVLLFHCVAHR

Method	From	To	amino acid sequence
SOSUI	1118	1140	IITYAALSLSLVALLVAFVLLSL
1150	1171	SIHKNLIAALFFSQLIFMVGIN
1176	1198	PFLCTVVAILLHYVSMGTFAWTL
1219	1240	MRFYHVVGWGIPAIVTGLAVGL
1262	1284	SFAGPVGTVIIINTVIFVLSAKV
1300	1322	SMLRTAFLLLLLVTATWLLGLLA
1332	1354	YLFAAFSCLQGIFVLLFHCVAHR

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	YES

Length of 3'UTR	1770 bp
Genome contig ID	gi65543215r_85847574
PolyA signal sequence (AATAAA,-25)	+--------+--------+----*----+---- ATGCATCTATAATAAATTAAGATTTTTGGATTTGT
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* ACCCGTGCTGTGCTGGGTGGTTACTGACCCCACTGTCCTACTCTCTAAGG

Gene/Protein Characteristic Table for mKIAA4041

Features of the cloned DNA sequence

Features of the protein sequence