ROUGE

Gene/Protein Characteristic Table for mKIAA1278

Link to : HUGE \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK173142
Description :	serine/threonine kinase 36.
Clone Name :	mfj16286 [Vector Info]
Source :	Mouse fetal brain

Features of the cloned DNA sequence	Description

Length: 5379 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 2091 bp

Genome contig ID gi65488608f_74803963
PolyA signal sequence
(ATTAAA,-20)
+----*----+----*----+----*----+----
TTCTGTCCTTCCTTAATTAAAGGTTTTAAGAAATG
Flanking genome sequence
(135398 - 135447)
----+----*----+----*----+----*----+----*----+----*
AAAGATGAGTGTGATTATCTGTATTTTATAAGGAGTTTTCTCATCTACTG

Genomic structure deduced by Blast search against draft genome sequences
Comparison with the corresponding KIAA cDNA.

KIAA Alignment based on:

KIAA1278 DNA sequence, AA sequence, Physical map

KIAA	Alignment based on:
KIAA1278	DNA sequence, AA sequence, Physical map

Features of the protein sequence	Description

Coding region: 98..880, 892..3171, 3560..4027, 4062..4346
Length: 1271 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
Q69ZM6	96.1	Serine/threonin...	Mus musculus
EDL00344	92.7	serine/threonin...	Mus musculus
NP_778196	92.5	serine/threonin...	Mus musculus
EDL00343	95.3	serine/threonin...	Mus musculus
EDL00346	90.0	serine/threonin...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AK173292	2.5e-22	38.9	mKIAA1901
AK220557	6.2e-22	33.0	mKIAA4230
AK033672	2.6e-21	29.7	mKIAA4088
AK220191	4.2e-21	34.4	mKIAA4207
AK173181	3.9e-20	36.1	mKIAA1477

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

BlastProDom IPR000719 44 261 PD000001 Protein kinase

HMMPfam IPR000719 41 311 PF00069 Protein kinase

IPR000357 1099 1130 PF02985 HEAT

HMMSmart IPR002290 41 464 SM00220 Serine/threonine protein kinase

IPR001245 41 294 SM00219 Tyrosine protein kinase

ProfileScan IPR000719 41 295 PS50011 Protein kinase

NULL 854 1151 PS50319 NULL

ScanRegExp IPR000719 47 70 PS00107 Protein kinase

IPR008271 158 170 PS00108 Serine/threonine protein kinase

Search method	interpro_ID	From	To	Entry	Definition
BlastProDom	IPR000719	44	261	PD000001	Protein kinase
HMMPfam	IPR000719	41	311	PF00069	Protein kinase
IPR000357	1099	1130	PF02985	HEAT
HMMSmart	IPR002290	41	464	SM00220	Serine/threonine protein kinase
IPR001245	41	294	SM00219	Tyrosine protein kinase
ProfileScan	IPR000719	41	295	PS50011	Protein kinase
NULL	854	1151	PS50319	NULL
ScanRegExp	IPR000719	47	70	PS00107	Protein kinase
IPR008271	158	170	PS00108	Serine/threonine protein kinase

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 917 936 LISPQGMAALLSLAMAIFTQ

980 1002 VVVLSVCKLLCFPFALDVDADLL

1014 1036 VVVCLLQVLPIGLLTRLALTDSA

1044 1066 TVATSSRAIISFLSVVLLSDQPL

Method	From	To	amino acid sequence
SOSUI	917	936	LISPQGMAALLSLAMAIFTQ
980	1002	VVVLSVCKLLCFPFALDVDADLL
1014	1036	VVVCLLQVLPIGLLTRLALTDSA
1044	1066	TVATSSRAIISFLSVVLLSDQPL

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	YES

Length of 3'UTR	2091 bp
Genome contig ID	gi65488608f_74803963
PolyA signal sequence (ATTAAA,-20)	+--------+--------+----*----+---- TTCTGTCCTTCCTTAATTAAAGGTTTTAAGAAATG
Flanking genome sequence (135398 - 135447)	----+--------+--------+--------+--------+----* AAAGATGAGTGTGATTATCTGTATTTTATAAGGAGTTTTCTCATCTACTG

Gene/Protein Characteristic Table for mKIAA1278

Features of the cloned DNA sequence

Features of the protein sequence