ROUGE

Gene/Protein Characteristic Table for mKIAA0358

Link to : HUGE \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK122257
Description :	MAP-kinase activating death domain. Rab3 GDP/GTP exchange protein. insulinoma-glucagonoma protein 20.
Clone Name :	mbg05815 [Vector Info]
Source :	Mouse brain

Features of the cloned DNA sequence	Description

Length: 5962 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 1050 bp

Genome contig ID gi66880554r_90742111
PolyA signal sequence
(AATAAA,-19)
+----*----+----*----+----*----+----
CAGCTGTGTGATGTGAAATAAATGTCCTGAACTCC
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
ACTTGGGCTCCTGTGCACTCCTCTCAGCCCGGGCCTGAGGAAGGCTGTCC

Genomic structure deduced by Blast search against draft genome sequences
Comparison with the corresponding KIAA cDNA.

KIAA Alignment based on:

KIAA0358 DNA sequence, AA sequence, Physical map

KIAA	Alignment based on:
KIAA0358	DNA sequence, AA sequence, Physical map

Features of the protein sequence	Description

Coding region: 167..4912
Length: 1581 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
EDL27542	99.9	MAP-kinase acti...	Mus musculus
Q80U28	100.0	MAP kinase-acti...	Mus musculus
CAM17576	99.8	MAP-kinase acti...	Mus musculus
EDL27531	98.4	MAP-kinase acti...	Mus musculus
EAW67936	95.4	MAP-kinase acti...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AJ245569	3e-06	24.4	mKIAA1091
AK129485	7.2e-06	25.0	mKIAA3020
AK173257	2.5e-05	24.0	mKIAA1766
AK173046	5.7e-05	22.8	mKIAA0870
AK081176	0.00015	27.5	mKIAA1277

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR005113 11 101 PF03456 uDENN

IPR001194 175 405 PF02141 DENN

IPR005112 488 561 PF03455 dDENN

ProfileScan IPR001194 257 405 PS50211 DENN

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR005113	11	101	PF03456	uDENN
IPR001194	175	405	PF02141	DENN
IPR005112	488	561	PF03455	dDENN
ProfileScan	IPR001194	257	405	PS50211	DENN

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 303 325 PLELLGVDACLQVLTCILLEHKV

336 358 SMSVMAFVAMIYPLEYMFPVIPL

369 391 LLLAPTPYIIGVPASFFLYKLDF

Method	From	To	amino acid sequence
SOSUI	303	325	PLELLGVDACLQVLTCILLEHKV
336	358	SMSVMAFVAMIYPLEYMFPVIPL
369	391	LLLAPTPYIIGVPASFFLYKLDF

How to obtain mKIAA clone(s) How to obtain anti mKIAA antibodies Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	YES

Length of 3'UTR	1050 bp
Genome contig ID	gi66880554r_90742111
PolyA signal sequence (AATAAA,-19)	+--------+--------+----*----+---- CAGCTGTGTGATGTGAAATAAATGTCCTGAACTCC
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* ACTTGGGCTCCTGTGCACTCCTCTCAGCCCGGGCCTGAGGAAGGCTGTCC

Gene/Protein Characteristic Table for mKIAA0358

Features of the cloned DNA sequence

Features of the protein sequence