-
SpecieshumanProduct IDFXC03022Cloning SiteSgfI-PmeIGeneKIBB8786SymbolMC2R
Alias : ACTHRDescriptionmelanocortin 2 receptor (adrenocorticotropic hormone)Original Clone IDcp00821
Length: 891 bp
Restriction map A
Restriction map B
Genomic Structure
-
Length: 297 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS11869.1 1.2e-62 100.0 MC2R CCDS11868.1 8.5e-28 46.5 MC5R CCDS11976.1 1.6e-27 47.3 MC4R CCDS56011.1 3.1e-21 40.7 MC1R CCDS13449.2 1.6e-15 47.9 MC3R
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ]
Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR001168 3 19 PR00520 Adrenocorticotrophin (ACTH) receptor IPR001168 20 30 PR00520 Adrenocorticotrophin (ACTH) receptor IPR000276 26 50 PR00237 GPCR IPR001671 51 63 PR00534 Melanocortin/ACTH receptor IPR000276 59 80 PR00237 GPCR IPR001168 88 102 PR00520 Adrenocorticotrophin (ACTH) receptor IPR001671 103 117 PR00534 Melanocortin/ACTH receptor IPR000276 110 132 PR00237 GPCR IPR001671 132 143 PR00534 Melanocortin/ACTH receptor IPR001168 158 171 PR00520 Adrenocorticotrophin (ACTH) receptor IPR000276 174 197 PR00237 GPCR IPR001168 202 216 PR00520 Adrenocorticotrophin (ACTH) receptor IPR001671 216 228 PR00534 Melanocortin/ACTH receptor IPR000276 217 241 PR00237 GPCR IPR001671 241 258 PR00534 Melanocortin/ACTH receptor IPR000276 258 284 PR00237 GPCR IPR001671 264 275 PR00534 Melanocortin/ACTH receptor IPR001671 280 293 PR00534 Melanocortin/ACTH receptor IPR001168 284 292 PR00520 Adrenocorticotrophin (ACTH) receptor HMMPfam IPR000276 41 276 PF00001 GPCR ProfileScan IPR017452 41 276 PS50262 GPCR
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 25 VLPEEIFFTISIVGVLENLIVLL 47 SECONDARY 23 2 63 ICSLAISDMLGSLYKILENILII 85 SECONDARY 23 3 102 ADDIIDSLFVLSLLGSIFSLSVI 124 SECONDARY 23 4 147 TVVVLTVIWTFCTGTGITMVIFS 169 PRIMARY 23 5 177 TFTSLFPLMLVFILCLYVHMFLL 199 PRIMARY 23 6 220 TLTILLGVFIFCWAPFVLHVLLM 242 PRIMARY 23 7 255 MSLFQVNGMLIMCNAVIDPFIYA 277 SECONDARY 23
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) XP_016881270 297 202200,607397 100.0 100.0 NP_000520 297 202200,607397 100.0 100.0 NP_001278840 297 202200,607397 100.0 100.0 NP_005904 325 600042 46.5 94.6 NP_005903 332 155541,601665 47.3 97.0 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB8786 Download>KIBB8786 891 bp ATGAAGCACATTATCAACTCGTATGAAAACATCAACAACACAGCAAGAAATAATTCCGAC TGTCCTCGTGTGGTTTTGCCGGAGGAGATATTTTTCACAATTTCCATTGTTGGAGTTTTG GAGAATCTGATCGTCCTGCTGGCTGTGTTCAAGAATAAGAATCTCCAGGCACCCATGTAC TTTTTCATCTGTAGCTTGGCCATATCTGATATGCTGGGCAGCCTATATAAGATCTTGGAA AATATCCTGATCATATTGAGAAACATGGGCTATCTCAAGCCACGTGGCAGTTTTGAAACC ACAGCCGATGACATCATCGACTCCCTGTTTGTCCTCTCCCTGCTTGGCTCCATCTTCAGC CTGTCTGTGATTGCTGCGGACCGCTACATCACCATCTTCCACGCACTGCGGTACCACAGC ATCGTGACCATGCGCCGCACTGTGGTGGTGCTTACGGTCATCTGGACGTTCTGCACGGGG ACTGGCATCACCATGGTGATCTTCTCCCATCATGTGCCCACAGTGATCACCTTCACGTCG CTGTTCCCGCTGATGCTGGTCTTCATCCTGTGCCTCTATGTGCACATGTTCCTGCTGGCT CGATCCCACACCAGGAAGATCTCCACCCTCCCCAGAGCCAACATGAAAGGGGCCATCACA CTGACCATCCTGCTCGGGGTCTTCATCTTCTGCTGGGCCCCCTTTGTGCTTCATGTCCTC TTGATGACATTCTGCCCAAGTAACCCCTACTGCGCCTGCTACATGTCTCTCTTCCAGGTG AACGGCATGTTGATCATGTGCAATGCCGTCATTGACCCCTTCATATATGCCTTCCGGAGC CCAGAGCTCAGGGACGCATTCAAAAAGATGATCTTCTGCAGCAGGTACTGG
Cloned ORF protein sequence for pF1KB8786 Download>KIBB8786 297 aa MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMY FFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFS LSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTS LFPLMLVFILCLYVHMFLLARSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVL LMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRYW
Nucleotide Sequence (with vector) for pF1KB8786 Download>pF1KB8786 4004 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGAAGCACATT ATCAACTCGTATGAAAACATCAACAACACAGCAAGAAATAATTCCGACTGTCCTCGTGTG GTTTTGCCGGAGGAGATATTTTTCACAATTTCCATTGTTGGAGTTTTGGAGAATCTGATC GTCCTGCTGGCTGTGTTCAAGAATAAGAATCTCCAGGCACCCATGTACTTTTTCATCTGT AGCTTGGCCATATCTGATATGCTGGGCAGCCTATATAAGATCTTGGAAAATATCCTGATC ATATTGAGAAACATGGGCTATCTCAAGCCACGTGGCAGTTTTGAAACCACAGCCGATGAC ATCATCGACTCCCTGTTTGTCCTCTCCCTGCTTGGCTCCATCTTCAGCCTGTCTGTGATT GCTGCGGACCGCTACATCACCATCTTCCACGCACTGCGGTACCACAGCATCGTGACCATG CGCCGCACTGTGGTGGTGCTTACGGTCATCTGGACGTTCTGCACGGGGACTGGCATCACC ATGGTGATCTTCTCCCATCATGTGCCCACAGTGATCACCTTCACGTCGCTGTTCCCGCTG ATGCTGGTCTTCATCCTGTGCCTCTATGTGCACATGTTCCTGCTGGCTCGATCCCACACC AGGAAGATCTCCACCCTCCCCAGAGCCAACATGAAAGGGGCCATCACACTGACCATCCTG CTCGGGGTCTTCATCTTCTGCTGGGCCCCCTTTGTGCTTCATGTCCTCTTGATGACATTC TGCCCAAGTAACCCCTACTGCGCCTGCTACATGTCTCTCTTCCAGGTGAACGGCATGTTG ATCATGTGCAATGCCGTCATTGACCCCTTCATATATGCCTTCCGGAGCCCAGAGCTCAGG GACGCATTCAAAAAGATGATCTTCTGCAGCAGGTACTGGGTTTAAACGAATTCGAGCTCG GTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGATCCGGCTGCTAACAA AGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATAACTAGCATAACCCCT TGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGGAGGAACTATATCCGGTTC GCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCATGTAAGCCCACTGCAAGCTAC CTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCAGTAGCTGACATTCAT CCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTGTTCCGCTTCCTTTAGCAGCC CTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAAGAATTGCCAGCTGGGGCGCCC TCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATGGCTTTCTTGCCGCCAAGGATC TGATGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGATGACGGTCGTTTCGCATGCTT GAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGGGTGGAGAGGCTATTCGGCTAT GACTGGGCACAACAGACAATCGGCTGCTCTGATGCCGCCGTGTTCCGGCTGTCAGCGCAG GGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGTGCCCTGAATGAACTGCAGGAC GAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTTCCTTGCGCAGCTGTGCTCGAC GTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGCGAAGTGCCGGGGCAGGATCTC CTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATCATGGCTGATGCAATGCGGCGG CTGCATACGCTTGATCCGGCTACCTGCCCATTCGACCACCAAGCGAAACATCGCATCGAG CGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAGGATGATCTGGACGAAGAGCAT CAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAGGCGCGTATGCCGGATGGTGAG GATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAATATCATGGTGGAAAATGGCCGC TTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCGGACCGCTATCAGGACATAGCG TTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAATGGGCTGACCGCTTCCTCGTG CTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCCTTCTATCGCCTTCTTGACGAG TTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACCAAGCGACGCCCAACCGGTATC AGCTCACTCAAAGGCGGTAATACGGTTATCCACAGAATCAGGGGATAACGCAGGAAAGAA CATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGCCGCGTTGCTGGCGTT TTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCAGAGGTG GCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGTGCG CTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAG CGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCGTTCGCTC CAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAA CTATCGTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACTGGCAGCAGCCACTGG TAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGTTCTTGAAGTGGTGGCC TAACTACGGCTACACTAGAAGGACAGTATTTGGTATCTGCGCTCTGCTGAAGCCAGTTAC CTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTAGCGGTGG TTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAAAGGATTTCAAGAAGATCCTTT GATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAGGGATTTTGGT CATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTATAGTCCGGAAATACAGGAAC GCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAATGGCAGCTTCAGTGGA TTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTATTCATACGGTTAAAAT TTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCATTTTTACCTGTCTGCT GCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAGGGATTATGGTAAATCC ACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACTCCGGCCACGATGCGTC CGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACAGATTAAATCAGAACGCAGAAGCGG TCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGTGGTCCCACCTGACCCCATGCC GAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGTGGGGTCTCCCCATGCGAGAGT AGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGTCGAAAGACTGGGCCTTTCGTT TTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGACAAATCCGCCGGGAGCGGATT TGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAGGACGCCCGCCATAAACTGCCA GGCATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCCTTTTTGCGTTTCTACAAACTC TTTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCAT
more Linker info
