-
SpecieshumanProduct IDFXC00037Cloning SiteSgfI-PmeISymbolLRRC8B
Alias : TA-LRRP, TALRRPDescriptionleucine rich repeat containing 8 family, member B, transcript variant 1
Length: 2409 bp
Restriction map A
Restriction map B
Genomic Structure
-
Length: 803 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS724.1 0 100.0 LRRC8B CCDS35155.1 9.9e-169 59.0 LRRC8A CCDS725.1 3e-146 50.2 LRRC8C CCDS12189.1 1.1e-130 47.1 LRRC8E CCDS726.1 1.3e-125 46.9 LRRC8D
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ]
Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR021040 1 66 PF12534 Leucine-rich repeat-containing protein 8 IPR021040 94 152 PF12534 Leucine-rich repeat-containing protein 8 IPR001611 609 633 PF00560 Leucine-rich repeat IPR001611 680 700 PF00560 Leucine-rich repeat IPR001611 749 770 PF00560 Leucine-rich repeat HMMSmart IPR003591 509 536 SM00369 Leucine-rich repeat IPR003591 584 607 SM00369 Leucine-rich repeat IPR003591 609 630 SM00369 Leucine-rich repeat IPR003591 632 654 SM00369 Leucine-rich repeat IPR003591 655 678 SM00369 Leucine-rich repeat IPR003591 679 700 SM00369 Leucine-rich repeat IPR003591 701 724 SM00369 Leucine-rich repeat IPR003591 747 770 SM00369 Leucine-rich repeat ProfileScan IPR001611 562 582 PS51450 Leucine-rich repeat IPR001611 586 607 PS51450 Leucine-rich repeat IPR001611 609 630 PS51450 Leucine-rich repeat IPR001611 634 655 PS51450 Leucine-rich repeat IPR001611 657 678 PS51450 Leucine-rich repeat IPR001611 680 701 PS51450 Leucine-rich repeat IPR001611 703 724 PS51450 Leucine-rich repeat IPR001611 726 747 PS51450 Leucine-rich repeat IPR001611 749 771 PS51450 Leucine-rich repeat
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 22 PWWDVFWYYITLIMLLVAVLAGA 44 SECONDARY 23 2 263 IVKVILFVLIITYVPYFLTHITL 285 PRIMARY 23 3 305 VYSLAEIFKVLASFYVILVILYG 327 PRIMARY 23
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) XP_005270759 803 612888 100.0 100.0 XP_011539448 803 612888 100.0 100.0 XP_011539447 803 612888 100.0 100.0 XP_011539446 803 612888 100.0 100.0 XP_016856373 803 612888 100.0 100.0 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KA0231 Download>KIAA0231 2409 bp ATGATTACACTAACTGAGCTAAAATGCTTAGCAGATGCCCAGTCATCTTATCACATCTTA AAACCATGGTGGGACGTCTTCTGGTATTACATCACACTGATCATGCTGCTGGTGGCCGTG CTGGCCGGAGCTCTCCAGCTGACGCAGAGCAGGGTTCTGTGCTGTCTTCCATGCAAAGTG GAATTTGACAATCACTGTGCCGTGCCTTGGGACATCCTGAAAGCCAGCATGAACACATCC TCTAATCCTGGGACACCGCTTCCGCTCCCCCTCCGAATTCAGAATGACCTCCACCGACAG CAGTACTCCTATATTGATGCCGTCTGTTACGAGAAACAGCTCCATTGGTTTGCAAAGTTT TTCCCCTATCTGGTGCTCTTGCACACGCTCATCTTTGCAGCCTGCAGCAACTTTTGGCTT CACTACCCCAGTACCAGTTCCAGGCTCGAGCATTTTGTGGCCATCCTTCACAAGTGCTTC GATTCTCCATGGACCACCCGCGCCCTTTCAGAAACAGTGGCTGAGCAGTCAGTGAGGCCT CTGAAACTCTCCAAGTCCAAGATTTTGCTTTCGTCCTCAGGGTGTTCAGCTGACATAGAT TCCGGCAAACAGTCATTGCCCTACCCACAGCCAGGTTTGGAGTCAGCTGGCATAGAAAGC CCAACTTCCAGTGTCCTGGACAAGAAGGAGGGTGAACAGGCCAAAGCCATCTTTGAAAAA GTGAAAAGATTCCGCATGCATGTGGAGCAGAAGGACATCATTTATAGAGTATATCTGAAA CAGATAATAGTCAAAGTCATTTTGTTTGTGCTCATCATAACTTATGTTCCATATTTTTTA ACCCACATCACTCTTGAAATCGACTGTTCAGTTGATGTGCAGGCTTTTACAGGATATAAG CGCTACCAGTGTGTCTATTCCTTGGCAGAAATCTTTAAGGTCCTGGCTTCATTTTATGTC ATTTTGGTTATACTTTATGGTCTGACCTCTTCCTACAGCCTGTGGTGGATGCTGAGGAGT TCCCTGAAGCAATATTCCTTTGAGGCGTTAAGAGAAAAAAGCAACTACAGTGACATCCCT GATGTCAAGAATGACTTTGCCTTCATCCTTCATCTGGCTGATCAGTATGATCCTCTTTAT TCCAAACGCTTCTCCATATTCCTATCAGAGGTCAGTGAGAACAAACTGAAACAGATCAAC CTCAATAATGAATGGACAGTTGAGAAACTGAAAAGTAAGCTTGTGAAAAATGCCCAGGAC AAGATAGAACTGCATCTTTTTATGCTCAACGGTCTTCCAGACAATGTCTTTGAGTTAACT GAAATGGAAGTGCTAAGCCTGGAGCTTATCCCAGAGGTGAAGCTGCCCTCTGCAGTCTCA CAGCTGGTCAACCTCAAGGAGCTTCGTGTGTACCATTCATCTCTGGTCGTAGACCATCCT GCACTGGCCTTTCTAGAGGAGAATTTAAAAATCCTCCGCCTGAAATTTACTGAAATGGGA AAAATCCCACGCTGGGTATTTCACCTCAAGAATCTCAAGGAACTTTATCTTTCGGGCTGT GTTCTCCCTGAACAGTTGAGTACTATGCAGTTGGAGGGCTTTCAGGACTTAAAAAATCTA AGGACCCTGTACTTGAAGAGCAGCCTCTCCCGGATCCCACAAGTTGTTACAGACCTCCTG CCTTCATTGCAGAAACTGTCCCTTGATAATGAGGGAAGCAAACTGGTTGTGTTGAACAAC TTGAAAAAGATGGTCAATCTGAAAAGCCTAGAACTGATCAGCTGTGACCTGGAACGCATC CCACATTCCATTTTCAGCCTGAATAATTTGCATGAGTTAGACCTAAGGGAAAATAACCTT AAAACTGTGGAAGAGATCATTAGCTTTCAGCATCTTCAGAATCTTTCCTGCTTAAAGTTG TGGCACAATAACATTGCTTATATTCCTGCACAGATTGGGGCATTATCTAACCTAGAGCAG CTCTCTTTGGACCATAATAATATTGAGAATCTGCCCTTGCAGCTTTTCCTATGCACTAAA CTACATTATTTGGATCTAAGCTATAACCACTTGACCTTCATTCCAGAAGAAATCCAGTAT CTGAGTAATTTGCAGTACTTTGCTGTGACCAACAACAATATTGAGATGCTACCAGATGGG CTGTTTCAGTGCAAAAAGCTGCAGTGTTTACTTTTGGGGAAAAATAGCTTGATGAATTTG TCCCCTCATGTGGGTGAGCTGTCAAACCTTACTCATCTGGAGCTCATTGGTAATTACCTG GAAACACTTCCTCCTGAACTAGAAGGATGTCAGTCCCTAAAACGGAACTGTCTGATTGTT GAGGAGAACTTGCTCAATACTCTTCCTCTCCCTGTAACAGAACGTTTACAGACGTGCTTA GACAAATGT
Cloned ORF protein sequence for pF1KA0231 Download>KIAA0231 803 aa MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV EENLLNTLPLPVTERLQTCLDKC
Nucleotide Sequence (with vector) for pF1KA0231 Download>pF1KA0231 5522 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGATTACACTA ACTGAGCTAAAATGCTTAGCAGATGCCCAGTCATCTTATCACATCTTAAAACCATGGTGG GACGTCTTCTGGTATTACATCACACTGATCATGCTGCTGGTGGCCGTGCTGGCCGGAGCT CTCCAGCTGACGCAGAGCAGGGTTCTGTGCTGTCTTCCATGCAAAGTGGAATTTGACAAT CACTGTGCCGTGCCTTGGGACATCCTGAAAGCCAGCATGAACACATCCTCTAATCCTGGG ACACCGCTTCCGCTCCCCCTCCGAATTCAGAATGACCTCCACCGACAGCAGTACTCCTAT ATTGATGCCGTCTGTTACGAGAAACAGCTCCATTGGTTTGCAAAGTTTTTCCCCTATCTG GTGCTCTTGCACACGCTCATCTTTGCAGCCTGCAGCAACTTTTGGCTTCACTACCCCAGT ACCAGTTCCAGGCTCGAGCATTTTGTGGCCATCCTTCACAAGTGCTTCGATTCTCCATGG ACCACCCGCGCCCTTTCAGAAACAGTGGCTGAGCAGTCAGTGAGGCCTCTGAAACTCTCC AAGTCCAAGATTTTGCTTTCGTCCTCAGGGTGTTCAGCTGACATAGATTCCGGCAAACAG TCATTGCCCTACCCACAGCCAGGTTTGGAGTCAGCTGGCATAGAAAGCCCAACTTCCAGT GTCCTGGACAAGAAGGAGGGTGAACAGGCCAAAGCCATCTTTGAAAAAGTGAAAAGATTC CGCATGCATGTGGAGCAGAAGGACATCATTTATAGAGTATATCTGAAACAGATAATAGTC AAAGTCATTTTGTTTGTGCTCATCATAACTTATGTTCCATATTTTTTAACCCACATCACT CTTGAAATCGACTGTTCAGTTGATGTGCAGGCTTTTACAGGATATAAGCGCTACCAGTGT GTCTATTCCTTGGCAGAAATCTTTAAGGTCCTGGCTTCATTTTATGTCATTTTGGTTATA CTTTATGGTCTGACCTCTTCCTACAGCCTGTGGTGGATGCTGAGGAGTTCCCTGAAGCAA TATTCCTTTGAGGCGTTAAGAGAAAAAAGCAACTACAGTGACATCCCTGATGTCAAGAAT GACTTTGCCTTCATCCTTCATCTGGCTGATCAGTATGATCCTCTTTATTCCAAACGCTTC TCCATATTCCTATCAGAGGTCAGTGAGAACAAACTGAAACAGATCAACCTCAATAATGAA TGGACAGTTGAGAAACTGAAAAGTAAGCTTGTGAAAAATGCCCAGGACAAGATAGAACTG CATCTTTTTATGCTCAACGGTCTTCCAGACAATGTCTTTGAGTTAACTGAAATGGAAGTG CTAAGCCTGGAGCTTATCCCAGAGGTGAAGCTGCCCTCTGCAGTCTCACAGCTGGTCAAC CTCAAGGAGCTTCGTGTGTACCATTCATCTCTGGTCGTAGACCATCCTGCACTGGCCTTT CTAGAGGAGAATTTAAAAATCCTCCGCCTGAAATTTACTGAAATGGGAAAAATCCCACGC TGGGTATTTCACCTCAAGAATCTCAAGGAACTTTATCTTTCGGGCTGTGTTCTCCCTGAA CAGTTGAGTACTATGCAGTTGGAGGGCTTTCAGGACTTAAAAAATCTAAGGACCCTGTAC TTGAAGAGCAGCCTCTCCCGGATCCCACAAGTTGTTACAGACCTCCTGCCTTCATTGCAG AAACTGTCCCTTGATAATGAGGGAAGCAAACTGGTTGTGTTGAACAACTTGAAAAAGATG GTCAATCTGAAAAGCCTAGAACTGATCAGCTGTGACCTGGAACGCATCCCACATTCCATT TTCAGCCTGAATAATTTGCATGAGTTAGACCTAAGGGAAAATAACCTTAAAACTGTGGAA GAGATCATTAGCTTTCAGCATCTTCAGAATCTTTCCTGCTTAAAGTTGTGGCACAATAAC ATTGCTTATATTCCTGCACAGATTGGGGCATTATCTAACCTAGAGCAGCTCTCTTTGGAC CATAATAATATTGAGAATCTGCCCTTGCAGCTTTTCCTATGCACTAAACTACATTATTTG GATCTAAGCTATAACCACTTGACCTTCATTCCAGAAGAAATCCAGTATCTGAGTAATTTG CAGTACTTTGCTGTGACCAACAACAATATTGAGATGCTACCAGATGGGCTGTTTCAGTGC AAAAAGCTGCAGTGTTTACTTTTGGGGAAAAATAGCTTGATGAATTTGTCCCCTCATGTG GGTGAGCTGTCAAACCTTACTCATCTGGAGCTCATTGGTAATTACCTGGAAACACTTCCT CCTGAACTAGAAGGATGTCAGTCCCTAAAACGGAACTGTCTGATTGTTGAGGAGAACTTG CTCAATACTCTTCCTCTCCCTGTAACAGAACGTTTACAGACGTGCTTAGACAAATGTGTT TAAACGAATTCGAGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGC TGATCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCA ATAACTAGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGG AGGAACTATATCCGGTTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCATGT AAGCCCACTGCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGC CCAGTAGCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTGTT CCGCTTCCTTTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAAGAA TTGCCAGCTGGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATGGCT TTCTTGCCGCCAAGGATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGATGA CGGTCGTTTCGCATGCTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGGGTG GAGAGGCTATTCGGCTATGACTGGGCACAACAGACAATCGGCTGCTCTGATGCCGCCGTG TTCCGGCTGTCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGTGCC CTGAATGAACTGCAGGACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTTCCT TGCGCAGCTGTGCTCGACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGCGAA GTGCCGGGGCAGGATCTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATCATG GCTGATGCAATGCGGCGGCTGCATACGCTTGATCCGGCTACCTGCCCATTCGACCACCAA GCGAAACATCGCATCGAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAGGAT GATCTGGACGAAGAGCATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAGGCG CGTATGCCGGATGGTGAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAATATC ATGGTGGAAAATGGCCGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCGGAC CGCTATCAGGACATAGCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAATGG GCTGACCGCTTCCTCGTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCCTTC TATCGCCTTCTTGACGAGTTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACCAAG CGACGCCCAACCGGACTATAAAAGGATCTAGGTGAAGATCCTTTTTGATAATCTCATGAC CAAAATCCCTTAACGTGAGTTTTCGTTCCACTGAGCGTCAGACCCCGTAGAAAAGATCAA AGGATCTTCTTGAAATCCTTTTTTTCTGCGCGTAATCTGCTGCTTGCAAACAAAAAAACC ACCGCTACCAGCGGTGGTTTGTTTGCCGGATCAAGAGCTACCAACTCTTTTTCCGAAGGT AACTGGCTTCAGCAGAGCGCAGATACCAAATACTGTCCTTCTAGTGTAGCCGTAGTTAGG CCACCACTTCAAGAACTCTGTAGCACCGCCTACATACCTCGCTCTGCTAATCCTGTTACC AGTGGCTGCTGCCAGTGGCGATAAGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTT ACCGGATAAGGCGCAGCGGTCGGGCTGAACGGGGGGTTCGTGCACACAGCCCAGCTTGGA GCGAACGACCTACACCGAACTGAGATACCTACAGCGTGAGCTATGAGAAAGCGCCACGCT TCCCGAAGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGCG CACGAGGGAGCTTCCAGGGGGAAACGCCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCA CCTCTGACTTGAGCGTCGATTTTTGTGATGCTCGTCAGGGGGGCGGAGCCTATGGAAAAA CGCCAGCAACGCGGCCTTTTTACGGTTCCTGGCCTTTTGCTGGCCTTTTGCTCACATGTT CTTTCCTGCGTTATCCCCTGATTCTGTGGATAACCGTATTACCGCCTTTGAGTGAGCTGA TACCGGAAATACAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAA AATGGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGG TATTCATACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGC CATTTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTA AGGGATTATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTA CTCCGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACAGATTAA ATCAGAACGCAGAAGCGGTCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGTGGT CCCACCTGACCCCATGCCGAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGTGGG GTCTCCCCATGCGAGAGTAGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGTCGA AAGACTGGGCCTTTCGTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGACAA ATCCGCCGGGAGCGGATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAGGAC GCCCGCCATAAACTGCCAGGCATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCCTTT TTGCGTTTCTACAAACTCTTTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTC AT
more Linker info
