Result of FASTA (omim) for pF1KA0231
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0231, 803 aa
  1>>>pF1KA0231 803 - 803 aa - 803 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4069+/-0.000477; mu= 15.0071+/- 0.030
 mean_var=106.6780+/-22.932, 0's: 0 Z-trim(111.2): 356  B-trim: 1176 in 2/49
 Lambda= 0.124176
 statistics sampled from 19331 (19789) to 19331 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.232), width:  16
 Scan time: 11.410

The best scores are:                                      opt bits E(85289)
XP_005270759 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
XP_011539448 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
XP_011539447 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
XP_011539446 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
XP_016856373 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
XP_016856372 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
XP_011539445 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
XP_005270758 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
XP_005270760 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
NP_056165 (OMIM: 612888) volume-regulated anion ch ( 803) 5285 958.7       0
NP_001127948 (OMIM: 612888) volume-regulated anion ( 803) 5285 958.7       0
XP_016856374 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7       0
XP_016856375 (OMIM: 612888) PREDICTED: volume-regu ( 731) 4676 849.5       0
XP_011539450 (OMIM: 612888) PREDICTED: volume-regu ( 731) 4676 849.5       0
XP_006717249 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
XP_011517165 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
NP_062540 (OMIM: 608360,613506) volume-regulated a ( 810) 3188 583.0 1.8e-165
XP_005252153 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
XP_005252152 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
XP_011517166 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
XP_011517167 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
NP_001120717 (OMIM: 608360,613506) volume-regulate ( 810) 3188 583.0 1.8e-165
NP_001120716 (OMIM: 608360,613506) volume-regulate ( 810) 3188 583.0 1.8e-165
NP_115646 (OMIM: 612889) volume-regulated anion ch ( 803) 2779 509.7  2e-143
XP_011540584 (OMIM: 612889) PREDICTED: volume-regu ( 803) 2778 509.5 2.2e-143
XP_016857992 (OMIM: 612889) PREDICTED: volume-regu ( 803) 2778 509.5 2.2e-143
XP_006711023 (OMIM: 612889) PREDICTED: volume-regu ( 808) 2778 509.5 2.3e-143
XP_011526621 (OMIM: 612891) PREDICTED: volume-regu ( 796) 2494 458.7 4.6e-128
NP_001255213 (OMIM: 612891) volume-regulated anion ( 796) 2494 458.7 4.6e-128
NP_079337 (OMIM: 612891) volume-regulated anion ch ( 796) 2494 458.7 4.6e-128
XP_016857089 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
XP_016857088 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
XP_016857090 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
NP_001127951 (OMIM: 612890) volume-regulated anion ( 858) 2402 442.2 4.5e-123
NP_060573 (OMIM: 612890) volume-regulated anion ch ( 858) 2402 442.2 4.5e-123
XP_016857091 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
XP_011539991 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
XP_016857993 (OMIM: 612889) PREDICTED: volume-regu ( 773) 2321 427.7 9.6e-119
XP_011540585 (OMIM: 612889) PREDICTED: volume-regu ( 778) 2321 427.7 9.7e-119
NP_001255214 (OMIM: 612891) volume-regulated anion ( 667) 2147 396.4 2.1e-109
NP_001255968 (OMIM: 602775,607721) leucine-rich re ( 536)  414 85.9   5e-16
NP_001311265 (OMIM: 602775,607721) leucine-rich re ( 582)  414 85.9 5.3e-16
NP_001311266 (OMIM: 602775,607721) leucine-rich re ( 582)  414 85.9 5.3e-16
NP_031399 (OMIM: 602775,607721) leucine-rich repea ( 582)  414 85.9 5.3e-16
XP_016872192 (OMIM: 602775,607721) PREDICTED: leuc ( 582)  414 85.9 5.3e-16
XP_016872193 (OMIM: 602775,607721) PREDICTED: leuc ( 582)  414 85.9 5.3e-16
XP_016872191 (OMIM: 602775,607721) PREDICTED: leuc ( 582)  414 85.9 5.3e-16
XP_016866486 (OMIM: 608195) PREDICTED: leucine-ric ( 331)  407 84.5 8.1e-16
NP_060684 (OMIM: 608195) leucine-rich repeat-conta ( 524)  407 84.7 1.2e-15
XP_011513028 (OMIM: 608195) PREDICTED: leucine-ric ( 524)  407 84.7 1.2e-15


>>XP_005270759 (OMIM: 612888) PREDICTED: volume-regulate  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
XP_005 EENLLNTLPLPVTERLQTCLDKC
              790       800   

>>XP_011539448 (OMIM: 612888) PREDICTED: volume-regulate  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
XP_011 EENLLNTLPLPVTERLQTCLDKC
              790       800   

>>XP_011539447 (OMIM: 612888) PREDICTED: volume-regulate  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
XP_011 EENLLNTLPLPVTERLQTCLDKC
              790       800   

>>XP_011539446 (OMIM: 612888) PREDICTED: volume-regulate  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
XP_011 EENLLNTLPLPVTERLQTCLDKC
              790       800   

>>XP_016856373 (OMIM: 612888) PREDICTED: volume-regulate  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
XP_016 EENLLNTLPLPVTERLQTCLDKC
              790       800   

>>XP_016856372 (OMIM: 612888) PREDICTED: volume-regulate  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
XP_016 EENLLNTLPLPVTERLQTCLDKC
              790       800   

>>XP_011539445 (OMIM: 612888) PREDICTED: volume-regulate  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
XP_011 EENLLNTLPLPVTERLQTCLDKC
              790       800   

>>XP_005270758 (OMIM: 612888) PREDICTED: volume-regulate  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
XP_005 EENLLNTLPLPVTERLQTCLDKC
              790       800   

>>XP_005270760 (OMIM: 612888) PREDICTED: volume-regulate  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
XP_005 EENLLNTLPLPVTERLQTCLDKC
              790       800   

>>NP_056165 (OMIM: 612888) volume-regulated anion channe  (803 aa)
 initn: 5285 init1: 5285 opt: 5285  Z-score: 5122.3  bits: 958.7 E(85289):    0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
              730       740       750       760       770       780

              790       800   
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
       :::::::::::::::::::::::
NP_056 EENLLNTLPLPVTERLQTCLDKC
              790       800   




803 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 18:23:19 2016 done: Wed Nov  2 18:23:21 2016
 Total Scan time: 11.410 Total Display time:  0.250

Function used was FASTA [36.3.4 Apr, 2011]
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