Gene/Protein Characteristic Table for KIAA0231
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Product ID ORK00037
Accession No D86984
Description leucine rich repeat containing 8 family, member B, transcript variant 1
Clone name fk16230
Vector information
The cDNA fragment was inserted at the SalI-NotI site of the ...
cDNA sequence DNA sequence (3615 bp)
Predicted protein sequence (823 aa)
Flexi ORF Clone FXC00037
Source Human fetal brain
Rouge ID mKIAA0231 by Kazusa Mouse cDNA Project
Note We replaced ha02410, former representative clones for KIAA0231 with fk16230. (2005/08/06)
Features of the cloned cDNA sequence
Description

Length: 3615 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis).

N-terminal truncation Coding interruption
cloned DNA seq No warning No warning
Integrity of 3' end
Length of 3'UTR 333 bp
Genome contig ID gi89161185f_89687489
PolyA signal sequence
(None)
+----*----+----*----+----*----+----
CACCAGCCTGGGTGACAGAGCAAGACTCTTATCTC
Flanking genome sequence
(144037 - 144086)
----+----*----+----*----+----*----+----*----+----*
AAAAAAAAAAAAAAAATGCTCCAGGGCTTTAAATGAGAAGTAAAATTTTC

Ensembl ContigView (Add our DAS server as a DAS source)


Chr f/r start end exon identity class
Ensembl gnome browser 1 f 89787489 89831524 6 99.7 Perfect prediction
Features of the protein sequence
Description

Length: 823 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
Q6P9F7 0 100.0 Leucine-rich re...
Homo sapiens
AAH60782 0 99.9 LRRC8B protein ...
Homo sapiens
XP_001150203 0 99.8 T-cell activati...
Pan troglodytes
AAQ88479 0 99.8 ITLT6413 [Homo ...
Homo sapiens
XP_001494263 0 97.0 leucine rich re...
Equus caballus
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against HUGE database (FASTA output, Multiple alignment)
Entry Exp ID% HUGE_ID
AB037858 5.4e-172 59.0 KIAA1437
AB020669 4.8e-18 27.4 KIAA0862
AB033051 5.2e-10 29.2 KIAA1225
D63481 3e-09 30.8 KIAA0147
AB046800 4.4e-07 29.8 KIAA1580
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR001611 630 643 PR00019 Leucine-rich repeat
IPR001611 675 688 PR00019 Leucine-rich repeat
HMMPfam IPR001611 531 557 PF00560 Leucine-rich repeat
IPR001611 606 627 PF00560 Leucine-rich repeat
IPR001611 629 652 PF00560 Leucine-rich repeat
IPR001611 654 675 PF00560 Leucine-rich repeat
IPR001611 677 698 PF00560 Leucine-rich repeat
IPR001611 700 721 PF00560 Leucine-rich repeat
IPR001611 769 790 PF00560 Leucine-rich repeat
HMMSmart IPR003591 529 556 SM00369 Leucine-rich repeat
IPR003591 604 627 SM00369 Leucine-rich repeat
IPR003591 629 650 SM00369 Leucine-rich repeat
IPR003591 652 674 SM00369 Leucine-rich repeat
IPR003591 675 698 SM00369 Leucine-rich repeat
IPR003591 699 720 SM00369 Leucine-rich repeat
IPR003591 721 744 SM00369 Leucine-rich repeat
IPR003591 767 790 SM00369 Leucine-rich repeat

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 5 LFNFFHCISVLLQGKVMITLTEL 27 SECONDARY 23
2 283 IVKVILFVLIITYVPYFLTHITL 305 PRIMARY 23
3 325 VYSLAEIFKVLASFYVILVILYG 347 PRIMARY 23
Expression profile
Description

Northern blot
Experimental conditions
Primer_f
Primer_r
PCR conditions test

RH mapping information
Description

Chromosome No.
Experimental conditions
Panel name
Primer_f -
Primer_r -
PCR product length -
PCR conditions -
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