HUGE

Gene/Protein Characteristic Table for KIAA0605

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK01984
Accession No. :	AB011177
Description :	ADAMTS-like protein 2 precursor.
HUGO Gene Name :	ADAMTS-like 2 (ADAMTSL2)
Clone Name :	hg03238a [Vector Info]
Flexi ORF Clone :	pF1KA0605
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4067 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 654 bp

Genome contig ID gi89161216f_135287440
PolyA signal sequence
(AATAAA,-26)
+----*----+----*----+----*----+----
ATCTACGTTAATAAAGTGGTCCTATTTATGGCGGC
Flanking genome sequence
(143023 - 143072)
----+----*----+----*----+----*----+----*----+----*
ATCATGGGGTCTCAGTTGCCTCTGGCTGGAGAAGTGGGTGGCCTGGGGAT

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 9 f 135387107 135430461 19 99.8 Perfect prediction

Features of the protein sequence	Description

Length: 1031 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
CAM24586	99.8	ADAMTS-like 2 [...	Homo sapiens
XP_001169765	97.8	ADAMTS-like 2 i...	Pan troglodytes
BAG72447	100.0	ADAMTS-like 2 [...	synthetic construct
EAW88095	99.9	ADAMTS-like 2, ...	Homo sapiens
Q86TH1	99.8	ADAMTS-like pro...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB095949	2.9e-30	25.0	KIAA2029
AB002364	8.9e-25	25.1	KIAA0366
AB014588	1.4e-22	33.9	KIAA0688
AB037767	2.1e-22	29.9	KIAA1346
AB033059	2.1e-21	32.7	KIAA1233

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR013273 136 154 PR01857 Peptidase M12B

IPR013273 254 273 PR01857 Peptidase M12B

IPR013273 274 293 PR01857 Peptidase M12B

HMMPfam IPR000884 131 185 PF00090 Thrombospondin

IPR010294 294 411 PF05986 ADAM-TS Spacer 1

IPR000884 706 765 PF00090 Thrombospondin

IPR000884 819 874 PF00090 Thrombospondin

IPR000884 939 960 PF00090 Thrombospondin

IPR010909 995 1028 PF08686 PLAC

HMMSmart IPR000884 130 186 SM00209 Thrombospondin

IPR000884 647 703 SM00209 Thrombospondin

IPR000884 705 766 SM00209 Thrombospondin

IPR000884 768 818 SM00209 Thrombospondin

IPR000884 821 870 SM00209 Thrombospondin

IPR000884 877 935 SM00209 Thrombospondin

IPR000884 937 988 SM00209 Thrombospondin

ProfileScan IPR000884 127 186 PS50092 Thrombospondin

IPR000884 702 766 PS50092 Thrombospondin

IPR000884 817 875 PS50092 Thrombospondin

IPR000884 933 988 PS50092 Thrombospondin

IPR010909 992 1030 PS50900 PLAC

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR013273	136	154	PR01857	Peptidase M12B
IPR013273	254	273	PR01857	Peptidase M12B
IPR013273	274	293	PR01857	Peptidase M12B
HMMPfam	IPR000884	131	185	PF00090	Thrombospondin
IPR010294	294	411	PF05986	ADAM-TS Spacer 1
IPR000884	706	765	PF00090	Thrombospondin
IPR000884	819	874	PF00090	Thrombospondin
IPR000884	939	960	PF00090	Thrombospondin
IPR010909	995	1028	PF08686	PLAC
HMMSmart	IPR000884	130	186	SM00209	Thrombospondin
IPR000884	647	703	SM00209	Thrombospondin
IPR000884	705	766	SM00209	Thrombospondin
IPR000884	768	818	SM00209	Thrombospondin
IPR000884	821	870	SM00209	Thrombospondin
IPR000884	877	935	SM00209	Thrombospondin
IPR000884	937	988	SM00209	Thrombospondin
ProfileScan	IPR000884	127	186	PS50092	Thrombospondin
IPR000884	702	766	PS50092	Thrombospondin
IPR000884	817	875	PS50092	Thrombospondin
IPR000884	933	988	PS50092	Thrombospondin
IPR010909	992	1030	PS50900	PLAC

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 60 TLVIWKRIGAGLVVTVALLPRM 81 SECONDARY 22

2 90 WAWFLLVLAVVAGDTVSTGST 110 PRIMARY 21

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	60	TLVIWKRIGAGLVVTVALLPRM	81	SECONDARY	22
2	90	WAWFLLVLAVVAGDTVSTGST	110	PRIMARY	21

Expression profile	Description

: RT-PCR Description

Experimental conditions

Primer_f
: CTAAGAGACGTGGCACTGAGC

Primer_r
: ACAAACACAGGATCCACGCAG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR	Description

RH mapping information	Description

Chromosome No.

: 9

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: CTAAGAGACGTGGCACTGAGC
Primer_r	: ACAAACACAGGATCCACGCAG
PCR product length	: 165 bp
PCR conditions	: 95 °C15 sec66 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	654 bp
Genome contig ID	gi89161216f_135287440
PolyA signal sequence (AATAAA,-26)	+--------+--------+----*----+---- ATCTACGTTAATAAAGTGGTCCTATTTATGGCGGC
Flanking genome sequence (143023 - 143072)	----+--------+--------+--------+--------+----* ATCATGGGGTCTCAGTTGCCTCTGGCTGGAGAAGTGGGTGGCCTGGGGAT

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	9	f	135387107	135430461	19	99.8	Perfect prediction

Gene/Protein Characteristic Table for KIAA0605

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information