Gene/Protein Characteristic Table for KIAA0006
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Product ID ORK04167
Accession No D25304
Description Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6, transcript variant 1
Clone name ha01154
Vector information
The cDNA fragment was inserted at the EcoRV-NotI site of the ...
cDNA sequence DNA sequence (4804 bp)
Predicted protein sequence (773 aa)
Flexi ORF Clone FXC04167
Source Myeloblast cell line (KG-1)
Rouge ID mKIAA0006 by Kazusa Mouse cDNA Project
Features of the cloned cDNA sequence
Description

Length: 4804 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis).

N-terminal truncation Coding interruption
cloned DNA seq Warning No warning
Integrity of 3' end
Length of 3'UTR 2480 bp
Genome contig ID gi89161218r_135475374
PolyA signal sequence
(AATAAA,-23)
+----*----+----*----+----*----+----
TCAATACATAAAAATAAACAGTGCTTTATAAAAAT
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AAGTCTTTTGCTTCTTTTTTTGCTAGCCGGTGTGCAGAAAGATTTCTTGT
Features of the protein sequence
Description

Length: 773 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
Q15052 0 100.0 Rho guanine nuc...
Homo sapiens
CAD97632 0 99.9 hypothetical pr...
Homo sapiens
XP_001083544 0 98.6 Rac/Cdc42 guani...
Macaca mulatta
XP_001489904 0 94.6 similar to Rho ...
Equus caballus
XP_870250 0 94.6 similar to Rho ...
Bos taurus
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against HUGE database (FASTA output, Multiple alignment)
Entry Exp ID% HUGE_ID
D63476 1.2e-72 59.4 KIAA0142
AB033082 3.7e-08 26.2 KIAA1256
AB037836 6.5e-07 25.6 KIAA1415
AB002335 1.7e-05 23.0 KIAA0337
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
BlastProDom IPR001452 161 211 PD000066 Src homology-3
FPrintScan IPR003096 28 43 PR00888 SM22/calponin
IPR003096 75 90 PR00888 SM22/calponin
IPR003096 96 110 PR00888 SM22/calponin
IPR001452 174 189 PR00452 Src homology-3
IPR001452 191 200 PR00452 Src homology-3
IPR001452 202 214 PR00452 Src homology-3
HMMPfam IPR001715 1 108 PF00307 Calponin-like actin-binding
IPR001452 160 214 PF00018 Src homology-3
IPR000219 242 417 PF00621 DH
IPR001849 447 545 PF00169 Pleckstrin-like
HMMSmart IPR001715 1 103 SM00033 Calponin-like actin-binding
IPR001452 160 215 SM00326 Src homology-3
IPR000219 242 417 SM00325 DH
IPR001849 447 547 SM00233 Pleckstrin-like
ProfileScan IPR001715 1 107 PS50021 Calponin-like actin-binding
IPR001452 157 216 PS50002 Src homology-3
IPR000219 238 418 PS50010 DH
IPR001849 440 545 PS50003 Pleckstrin-like
Expression profile
Description

Northern blot
Experimental conditions
Primer_f
Primer_r
PCR conditions test

RH mapping information
Description

Chromosome No. X
Experimental conditions
Panel name Genebridge 4
Primer_f AACGAAGCTTGTGCAGAGTG
Primer_r CCTCTACGGGCAGCAGTTTA
PCR product length 163 bp
PCR conditions 95 °C15 sec61 °C60 sec30 cycles
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