ROUGE

Gene/Protein Characteristic Table for mKIAA4184

Link to : HUGE \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK220530
Description :	glutamate receptor, ionotropic, AMPA3 (alpha 3). cAMP-dependent Rap1 guanine-nucleotide exchange factor.
Clone Name :	mbg07034 [Vector Info]
Source :	Mouse brain

Features of the cloned DNA sequence	Description

Length: 4993 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 2275 bp

Genome contig ID gi66880665f_35822311
PolyA signal sequence
(AATAAA,-20)
+----*----+----*----+----*----+----
TTAATACATTTTGTAAATAAAATTGTAAAGAAAGC
Flanking genome sequence
(377088 - 377137)
----+----*----+----*----+----*----+----*----+----*
ATTCTGTCTCTGCACTTTGACTAGCTGCTTGCTGTATACTTGATGCAGAT

Genomic structure deduced by Blast search against draft genome sequences

Features of the protein sequence	Description

Coding region: 1..2715
Length: 905 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
BAG10748	99.4	glutamate recep...	synthetic construct
AAA67922	99.3	glutamate recep...	Homo sapiens
CAI95684	99.3	glutamate recep...	Homo sapiens
AAF61848	99.2	glutamate recep...	Homo sapiens
Q9Z2W9	99.9	Glutamate recep...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AK173314	7.4e-15	22.5	mKIAA1973

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR001828 57 401 PF01094 Extracellular ligand-binding receptor

IPR001320 563 856 PF00060 Ionotropic glutamate receptor

HMMSmart IPR001320 435 812 SM00079 Ionotropic glutamate receptor

ProfileScan IPR001311 445 547 PS50121 Solute-binding protein/glutamate receptor

IPR001622 611 667 PS50265 K+ channel

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR001828	57	401	PF01094	Extracellular ligand-binding receptor
IPR001320	563	856	PF00060	Ionotropic glutamate receptor
HMMSmart	IPR001320	435	812	SM00079	Ionotropic glutamate receptor
ProfileScan	IPR001311	445	547	PS50121	Solute-binding protein/glutamate receptor
IPR001622	611	667	PS50265	K+ channel

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 560 582 DPLAYEIWMCIVFAYIGVSVVLF

613 635 EFGIFNSLWFSLGAFMQQGCDIS

648 670 WWFFTLIIISSYTANLAAFLTVE

833 855 SNVAGVFYILVGGLGLAMMVALI

Method	From	To	amino acid sequence
SOSUI	560	582	DPLAYEIWMCIVFAYIGVSVVLF
613	635	EFGIFNSLWFSLGAFMQQGCDIS
648	670	WWFFTLIIISSYTANLAAFLTVE
833	855	SNVAGVFYILVGGLGLAMMVALI

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	2275 bp
Genome contig ID	gi66880665f_35822311
PolyA signal sequence (AATAAA,-20)	+--------+--------+----*----+---- TTAATACATTTTGTAAATAAAATTGTAAAGAAAGC
Flanking genome sequence (377088 - 377137)	----+--------+--------+--------+--------+----* ATTCTGTCTCTGCACTTTGACTAGCTGCTTGCTGTATACTTGATGCAGAT

Gene/Protein Characteristic Table for mKIAA4184

Features of the cloned DNA sequence

Features of the protein sequence