ROUGE

Gene/Protein Characteristic Table for mKIAA0886

Link to : HUGE \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK220511
Description :	Reticulon 4.
Clone Name :	mfj56082 [Vector Info]
Source :	Mouse fetal brain
Note :	This cDNA was previously called as mKIAA4153.

Features of the cloned DNA sequence	Description

Length: 4648 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 908 bp

Genome contig ID gi65527427f_29487738
PolyA signal sequence
(AATAAA,-18)
+----*----+----*----+----*----+----
CTGTAAAGCAAAGTATCAATAAAGCTTATAGACTT
Flanking genome sequence
(149970 - 150019)
----+----*----+----*----+----*----+----*----+----*
ACCTTTGTGTTTAGTGTTTTAGTTTCATGAATGCACAGCAAAAACACGGT

Genomic structure deduced by Blast search against draft genome sequences
Comparison with the corresponding KIAA cDNA.

KIAA Alignment based on:

KIAA0886 DNA sequence, AA sequence, Physical map

KIAA	Alignment based on:
KIAA0886	DNA sequence, AA sequence, Physical map

Features of the protein sequence	Description

Coding region: 3..3740
Length: 1245 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
EDL23797	99.6	reticulon 4, is...	Mus musculus
Q99P72	99.1	Reticulon-4; Ne...	Mus musculus
AAM77068	99.2	nogo-A [Mus mus...	Mus musculus
Q9JK11	91.1	Reticulon-4; Ne...	Rattus norvegicus
AAM73502	97.0	RTN4 [Mus muscu...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AY102283	2.4e-21	100.0	mKIAA0886

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR003388 1058 1243 PF02453 Reticulon

ProfileScan NULL 114 140 PS50313 NULL

IPR000694 151 243 PS50099 Proline-rich region

IPR003388 1058 1245 PS50845 Reticulon

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR003388	1058	1243	PF02453	Reticulon
ProfileScan	NULL	114	140	PS50313	NULL
IPR000694	151	243	PS50099	Proline-rich region
IPR003388	1058	1245	PS50845	Reticulon

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 33 55 SLIVPGAVAFAGSSAWFGQPGLC

1059 1081 VDLLYWRDIKKTGVVFGASLFLL

1087 1109 FSIVSVTAYIALALLSVTISFRI

1162 1184 LFLVDDLVDSLKFAVLMWVFTYV

1188 1210 FNGLTLLILALISLFSIPVIYER

Method	From	To	amino acid sequence
SOSUI	33	55	SLIVPGAVAFAGSSAWFGQPGLC
1059	1081	VDLLYWRDIKKTGVVFGASLFLL
1087	1109	FSIVSVTAYIALALLSVTISFRI
1162	1184	LFLVDDLVDSLKFAVLMWVFTYV
1188	1210	FNGLTLLILALISLFSIPVIYER

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	908 bp
Genome contig ID	gi65527427f_29487738
PolyA signal sequence (AATAAA,-18)	+--------+--------+----*----+---- CTGTAAAGCAAAGTATCAATAAAGCTTATAGACTT
Flanking genome sequence (149970 - 150019)	----+--------+--------+--------+--------+----* ACCTTTGTGTTTAGTGTTTTAGTTTCATGAATGCACAGCAAAAACACGGT

Gene/Protein Characteristic Table for mKIAA0886

Features of the cloned DNA sequence

Features of the protein sequence