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SpecieshumanProduct IDFXC02305Cloning SiteSgfI-PmeIGeneKIBB7185SymbolHCRTR2
Alias : ORXR2, OX2R, OXR2Descriptionhypocretin (orexin) receptor 2Original Clone IDoc00489
Length: 1332 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 444 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS4956.1 2.3e-143 100.0 HCRTR2 CCDS344.1 3.2e-88 69.2 HCRTR1 CCDS3552.1 8.7e-21 32.1 NPFFR2 CCDS47072.1 8.8e-21 32.1 NPFFR2 CCDS3551.1 1e-20 32.1 NPFFR2
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR000204 26 37 PR01064 Orexin receptor IPR000204 39 55 PR01064 Orexin receptor IPR000276 56 80 PR00237 GPCR IPR000276 89 110 PR00237 GPCR IPR000204 107 123 PR01064 Orexin receptor IPR000276 134 156 PR00237 GPCR IPR000204 159 170 PR01064 Orexin receptor IPR000276 168 189 PR00237 GPCR IPR000204 198 214 PR01064 Orexin receptor IPR000204 214 232 PR01064 Orexin receptor IPR000276 224 247 PR00237 GPCR IPR000204 247 267 PR01064 Orexin receptor IPR000204 288 304 PR01064 Orexin receptor IPR000276 302 326 PR00237 GPCR IPR000204 327 351 PR01064 Orexin receptor IPR000276 346 372 PR00237 GPCR IPR004060 384 398 PR01522 Orexin receptor IPR004060 399 410 PR01522 Orexin receptor IPR004060 411 424 PR01522 Orexin receptor IPR000204 418 431 PR01064 Orexin receptor IPR004060 429 444 PR01522 Orexin receptor HMMPfam IPR000276 71 364 PF00001 GPCR IPR004060 384 444 PF03827 Orexin receptor ProfileScan IPR017452 71 364 PS50262 GPCR
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 56 VLIAGYIIVFVVALIGNVLVCVA 78 PRIMARY 23 2 92 FIVNLSLADVLVTITCLPATLVV 114 SECONDARY 23 3 127 CKVIPYLQTVSVSVSVLTLSCIA 149 PRIMARY 23 4 174 VIIWIVSCIIMIPQAIVMECSTV 196 PRIMARY 23 5 222 MYHICFFLVTYMAPLCLMVLAYL 244 PRIMARY 23 6 305 MLMIVLLVFAICYLPISILNVL 326 PRIMARY 22
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_001517 444 602393 100.0 100.0 XP_016866287 461 602393 100.0 100.0 XP_016856595 425 602392 69.2 92.3 XP_016856594 425 602392 69.2 92.3 NP_001516 425 602392 69.2 92.3 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB7185 Download>KIBB7185 1332 bp ATGTCCGGCACCAAATTGGAGGACTCCCCCCCTTGTCGCAACTGGTCATCTGCTTCGGAG CTGAATGAAACTCAAGAGCCCTTTTTAAACCCCACCGACTATGACGACGAGGAATTCCTG CGGTACCTGTGGAGGGAATACCTGCACCCGAAAGAATATGAGTGGGTCCTGATCGCCGGG TACATCATCGTGTTCGTCGTGGCTCTCATTGGGAACGTCCTGGTTTGTGTGGCAGTGTGG AAGAACCACCACATGAGGACGGTAACCAACTACTTCATAGTCAATCTTTCTCTGGCTGAT GTGCTCGTGACCATCACCTGCCTTCCAGCCACACTGGTCGTGGATATCACTGAGACCTGG TTTTTTGGACAGTCCCTTTGCAAAGTGATTCCTTATCTACAGACCGTGTCGGTGTCTGTG TCTGTCCTCACACTGAGCTGTATCGCCTTGGATCGGTGGTATGCAATCTGTCACCCTTTG ATGTTTAAGAGCACAGCAAAGCGGGCCCGTAACAGCATTGTCATCATCTGGATTGTCTCC TGCATTATAATGATTCCTCAGGCCATCGTCATGGAGTGCAGCACCGTGTTCCCAGGCTTA GCCAATAAAACCACCCTCTTTACGGTGTGTGATGAGCGCTGGGGTGGTGAAATTTATCCC AAGATGTACCACATCTGTTTCTTTCTGGTGACATACATGGCACCACTGTGTCTCATGGTG TTGGCTTATCTGCAAATATTTCGCAAACTCTGGTGTCGACAGATCCCTGGAACATCATCT GTAGTTCAGAGAAAATGGAAGCCCCTGCAGCCTGTTTCACAGCCTCGAGGGCCAGGACAG CCAACGAAGTCCCGGATGAGCGCTGTGGCGGCTGAAATAAAGCAGATCCGAGCCAGAAGG AAAACAGCCCGGATGTTGATGATTGTGCTTTTGGTATTTGCAATTTGCTATCTACCAATT AGCATCCTCAATGTGCTAAAGAGAGTATTTGGGATGTTTGCCCATACTGAAGACAGAGAG ACTGTGTATGCCTGGTTTACCTTTTCACACTGGCTTGTATATGCCAATAGTGCTGCGAAT CCAATTATTTATAATTTTCTCAGTGGAAAATTTCGAGAGGAATTTAAAGCTGCGTTTTCT TGCTGTTGCCTTGGAGTTCACCATCGCCAGGAGGATCGGCTCACCAGGGGACGAACTAGC ACAGAGAGCCGGAAGTCCTTGACCACTCAAATCAGCAACTTTGATAACATATCAAAACTT TCTGAGCAAGTTGTGCTCACTAGCATAAGCACACTCCCAGCAGCCAATGGAGCAGGACCA CTTCAAAACTGG
Cloned ORF protein sequence for pF1KB7185 Download>KIBB7185 444 aa MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL SEQVVLTSISTLPAANGAGPLQNW
Nucleotide Sequence (with vector) for pF1KB7185 Download>pF1KB7185 4445 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGTCCGGCACC AAATTGGAGGACTCCCCCCCTTGTCGCAACTGGTCATCTGCTTCGGAGCTGAATGAAACT CAAGAGCCCTTTTTAAACCCCACCGACTATGACGACGAGGAATTCCTGCGGTACCTGTGG AGGGAATACCTGCACCCGAAAGAATATGAGTGGGTCCTGATCGCCGGGTACATCATCGTG TTCGTCGTGGCTCTCATTGGGAACGTCCTGGTTTGTGTGGCAGTGTGGAAGAACCACCAC ATGAGGACGGTAACCAACTACTTCATAGTCAATCTTTCTCTGGCTGATGTGCTCGTGACC ATCACCTGCCTTCCAGCCACACTGGTCGTGGATATCACTGAGACCTGGTTTTTTGGACAG TCCCTTTGCAAAGTGATTCCTTATCTACAGACCGTGTCGGTGTCTGTGTCTGTCCTCACA CTGAGCTGTATCGCCTTGGATCGGTGGTATGCAATCTGTCACCCTTTGATGTTTAAGAGC ACAGCAAAGCGGGCCCGTAACAGCATTGTCATCATCTGGATTGTCTCCTGCATTATAATG ATTCCTCAGGCCATCGTCATGGAGTGCAGCACCGTGTTCCCAGGCTTAGCCAATAAAACC ACCCTCTTTACGGTGTGTGATGAGCGCTGGGGTGGTGAAATTTATCCCAAGATGTACCAC ATCTGTTTCTTTCTGGTGACATACATGGCACCACTGTGTCTCATGGTGTTGGCTTATCTG CAAATATTTCGCAAACTCTGGTGTCGACAGATCCCTGGAACATCATCTGTAGTTCAGAGA AAATGGAAGCCCCTGCAGCCTGTTTCACAGCCTCGAGGGCCAGGACAGCCAACGAAGTCC CGGATGAGCGCTGTGGCGGCTGAAATAAAGCAGATCCGAGCCAGAAGGAAAACAGCCCGG ATGTTGATGATTGTGCTTTTGGTATTTGCAATTTGCTATCTACCAATTAGCATCCTCAAT GTGCTAAAGAGAGTATTTGGGATGTTTGCCCATACTGAAGACAGAGAGACTGTGTATGCC TGGTTTACCTTTTCACACTGGCTTGTATATGCCAATAGTGCTGCGAATCCAATTATTTAT AATTTTCTCAGTGGAAAATTTCGAGAGGAATTTAAAGCTGCGTTTTCTTGCTGTTGCCTT GGAGTTCACCATCGCCAGGAGGATCGGCTCACCAGGGGACGAACTAGCACAGAGAGCCGG AAGTCCTTGACCACTCAAATCAGCAACTTTGATAACATATCAAAACTTTCTGAGCAAGTT GTGCTCACTAGCATAAGCACACTCCCAGCAGCCAATGGAGCAGGACCACTTCAAAACTGG GTTTAAACGAATTCGAGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCA AGCTGATCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGA GCAATAACTAGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAA AGGAGGAACTATATCCGGTTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCA TGTAAGCCCACTGCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGAT AGCCCAGTAGCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGT GTTCCGCTTCCTTTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAA GAATTGCCAGCTGGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATG GCTTTCTTGCCGCCAAGGATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGA TGACGGTCGTTTCGCATGCTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGG GTGGAGAGGCTATTCGGCTATGACTGGGCACAACAGACAATCGGCTGCTCTGATGCCGCC GTGTTCCGGCTGTCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGT GCCCTGAATGAACTGCAGGACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTT CCTTGCGCAGCTGTGCTCGACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGC GAAGTGCCGGGGCAGGATCTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATC ATGGCTGATGCAATGCGGCGGCTGCATACGCTTGATCCGGCTACCTGCCCATTCGACCAC CAAGCGAAACATCGCATCGAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAG GATGATCTGGACGAAGAGCATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAG GCGCGTATGCCGGATGGTGAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAAT ATCATGGTGGAAAATGGCCGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCG GACCGCTATCAGGACATAGCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAA TGGGCTGACCGCTTCCTCGTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCC TTCTATCGCCTTCTTGACGAGTTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACC AAGCGACGCCCAACCGGTATCAGCTCACTCAAAGGCGGTAATACGGTTATCCACAGAATC AGGGGATAACGCAGGAAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAA AAAGGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAA TCGACGCTCAAGTCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCC CCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTC CGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAG TTCGGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGA CCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACTTATC GCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTAC AGAGTTCTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGGACAGTATTTGGTATCTG CGCTCTGCTGAAGCCAGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACA AACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAA AGGATTTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAA CTCACGTTAAGGGATTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTT ATAGTCCGGAAATACAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATG AAAAATGGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCAT AGGTATTCATACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGT TGCCATTTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAA TTAAGGGATTATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCA GTACTCCGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACAGAT TAAATCAGAACGCAGAAGCGGTCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGT GGTCCCACCTGACCCCATGCCGAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGT GGGGTCTCCCCATGCGAGAGTAGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGT CGAAAGACTGGGCCTTTCGTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGA CAAATCCGCCGGGAGCGGATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAG GACGCCCGCCATAAACTGCCAGGCATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCC TTTTTGCGTTTCTACAAACTCTTTTGTTTATTTTTCTAAATACATTCAAATATGTATCCG CTCAT
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