Result of FASTA (omim) for pF1KB7185
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7185, 444 aa
  1>>>pF1KB7185 444 - 444 aa - 444 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.5364+/-0.00041; mu= 22.8713+/- 0.026
 mean_var=111.4595+/-27.306, 0's: 0 Z-trim(113.3): 635  B-trim: 1263 in 1/51
 Lambda= 0.121483
 statistics sampled from 21804 (22601) to 21804 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.265), width:  16
 Scan time:  8.710

The best scores are:                                      opt bits E(85289)
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 3006 538.3 1.5e-152
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 3006 538.3 1.5e-152
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 1892 343.1 8.7e-94
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 1892 343.1 8.7e-94
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 1892 343.1 8.7e-94
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 1746 317.4 4.2e-86
NP_444264 (OMIM: 607449) neuropeptide FF receptor  ( 420)  530 104.3 6.2e-22
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423)  530 104.3 6.2e-22
NP_004876 (OMIM: 607449) neuropeptide FF receptor  ( 522)  530 104.5   7e-22
NP_071429 (OMIM: 607448) neuropeptide FF receptor  ( 430)  491 97.5 7.2e-20
NP_937822 (OMIM: 606925) pyroglutamylated RFamide  ( 431)  475 94.7   5e-19
NP_000785 (OMIM: 126449) D(1A) dopamine receptor [ ( 446)  450 90.4 1.1e-17
NP_057624 (OMIM: 605569) probable G-protein couple ( 423)  438 88.2 4.5e-17
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370)  429 86.6 1.2e-16
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381)  422 85.3 2.9e-16
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381)  422 85.3 2.9e-16
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381)  422 85.3 2.9e-16
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520)  418 84.8 5.7e-16
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384)  415 84.1 6.9e-16
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384)  415 84.1 6.9e-16
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390)  406 82.6 2.1e-15
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311)  399 81.2 4.3e-15
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393)  400 81.5 4.3e-15
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407)  399 81.4   5e-15
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348)  397 80.9 5.8e-15
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516)  398 81.3 6.4e-15
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447)  397 81.1 6.7e-15
NP_001304021 (OMIM: 602001) neuropeptide Y recepto ( 445)  395 80.7 8.5e-15
NP_001304020 (OMIM: 602001) neuropeptide Y recepto ( 445)  395 80.7 8.5e-15
XP_011530319 (OMIM: 602001) PREDICTED: neuropeptid ( 445)  395 80.7 8.5e-15
XP_005263095 (OMIM: 602001) PREDICTED: neuropeptid ( 445)  395 80.7 8.5e-15
NP_006165 (OMIM: 602001) neuropeptide Y receptor t ( 445)  395 80.7 8.5e-15
XP_016863744 (OMIM: 602001) PREDICTED: neuropeptid ( 452)  395 80.7 8.6e-15
XP_011530317 (OMIM: 602001) PREDICTED: neuropeptid ( 452)  395 80.7 8.6e-15
XP_016863745 (OMIM: 602001) PREDICTED: neuropeptid ( 452)  395 80.7 8.6e-15
NP_000669 (OMIM: 104219) alpha-1D adrenergic recep ( 572)  394 80.7 1.1e-14
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375)  389 79.6 1.6e-14
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  389 79.6 1.6e-14
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  389 79.6 1.6e-14
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375)  389 79.6 1.6e-14
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  389 79.6 1.6e-14
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  389 79.6 1.6e-14
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384)  381 78.2 4.3e-14
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384)  381 78.2 4.3e-14
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384)  381 78.2 4.3e-14
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384)  377 77.5   7e-14
NP_000721 (OMIM: 118444) cholecystokinin receptor  ( 428)  377 77.5 7.4e-14
XP_016864182 (OMIM: 606925) PREDICTED: pyroglutamy ( 190)  372 76.1 8.7e-14
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic  ( 477)  373 76.9 1.3e-13
XP_016874005 (OMIM: 118445) PREDICTED: gastrin/cho ( 381)  371 76.4 1.4e-13


>>NP_001517 (OMIM: 602393) orexin receptor type 2 [Homo   (444 aa)
 initn: 3006 init1: 3006 opt: 3006  Z-score: 2859.8  bits: 538.3 E(85289): 1.5e-152
Smith-Waterman score: 3006; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)

               10        20        30        40        50        60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
              370       380       390       400       410       420

              430       440    
pF1KB7 SEQVVLTSISTLPAANGAGPLQNW
       ::::::::::::::::::::::::
NP_001 SEQVVLTSISTLPAANGAGPLQNW
              430       440    

>>XP_016866287 (OMIM: 602393) PREDICTED: orexin receptor  (461 aa)
 initn: 3006 init1: 3006 opt: 3006  Z-score: 2859.6  bits: 538.3 E(85289): 1.5e-152
Smith-Waterman score: 3006; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)

               10        20        30        40        50        60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
              370       380       390       400       410       420

              430       440                     
pF1KB7 SEQVVLTSISTLPAANGAGPLQNW                 
       ::::::::::::::::::::::::                 
XP_016 SEQVVLTSISTLPAANGAGPLQNWCLQQGPPSSLPSTWLDV
              430       440       450       460 

>>XP_016856595 (OMIM: 602392) PREDICTED: orexin receptor  (425 aa)
 initn: 1853 init1: 1261 opt: 1892  Z-score: 1804.8  bits: 343.1 E(85289): 8.7e-94
Smith-Waterman score: 1892; 69.2% identity (85.6% similar) in 416 aa overlap (24-433:17-425)

               10        20        30        40        50        60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
                              ..::   : ::.:: :::::::.::.::.:::::::.
XP_016        MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
                      10        20        30         40        50  

               70        80        90       100       110       120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
       :. ::::::.::.:::.:::.:::::::::::::::::::::::  ::::.:.:::::.:
XP_016 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
             60        70        80        90       100       110  

              130       140       150       160       170       180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
       .::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
XP_016 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
            120       130       140       150       160       170  

              190       200       210       220       230       240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
         ::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
XP_016 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
            180       190       200       210       220       230  

              250       260       270            280       290     
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
       .::.::::::: ::::::.:.. :.::  .: .:     .:  :.: . :  :  ::.::
XP_016 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
            240       250         260       270        280         

         300       310       320       330       340       350     
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
       .:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
XP_016 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
     290       300       310       320       330       340         

         360       370       380       390       400       410     
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
       ::::::::::::::::::.::::::::  :.      .    :.:. :.:::. :     
XP_016 NSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQSRC--
     350       360       370       380       390        400        

         420       430        440    
pF1KB7 NISKLSEQVVLTSIST-LPAANGAGPLQNW
       .:::.::.:::::..: ::           
XP_016 SISKISEHVVLTSVTTVLP           
        410       420                

>>XP_016856594 (OMIM: 602392) PREDICTED: orexin receptor  (425 aa)
 initn: 1853 init1: 1261 opt: 1892  Z-score: 1804.8  bits: 343.1 E(85289): 8.7e-94
Smith-Waterman score: 1892; 69.2% identity (85.6% similar) in 416 aa overlap (24-433:17-425)

               10        20        30        40        50        60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
                              ..::   : ::.:: :::::::.::.::.:::::::.
XP_016        MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
                      10        20        30         40        50  

               70        80        90       100       110       120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
       :. ::::::.::.:::.:::.:::::::::::::::::::::::  ::::.:.:::::.:
XP_016 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
             60        70        80        90       100       110  

              130       140       150       160       170       180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
       .::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
XP_016 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
            120       130       140       150       160       170  

              190       200       210       220       230       240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
         ::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
XP_016 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
            180       190       200       210       220       230  

              250       260       270            280       290     
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
       .::.::::::: ::::::.:.. :.::  .: .:     .:  :.: . :  :  ::.::
XP_016 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
            240       250         260       270        280         

         300       310       320       330       340       350     
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
       .:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
XP_016 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
     290       300       310       320       330       340         

         360       370       380       390       400       410     
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
       ::::::::::::::::::.::::::::  :.      .    :.:. :.:::. :     
XP_016 NSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQSRC--
     350       360       370       380       390        400        

         420       430        440    
pF1KB7 NISKLSEQVVLTSIST-LPAANGAGPLQNW
       .:::.::.:::::..: ::           
XP_016 SISKISEHVVLTSVTTVLP           
        410       420                

>>NP_001516 (OMIM: 602392) orexin receptor type 1 [Homo   (425 aa)
 initn: 1853 init1: 1261 opt: 1892  Z-score: 1804.8  bits: 343.1 E(85289): 8.7e-94
Smith-Waterman score: 1892; 69.2% identity (85.6% similar) in 416 aa overlap (24-433:17-425)

               10        20        30        40        50        60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
                              ..::   : ::.:: :::::::.::.::.:::::::.
NP_001        MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
                      10        20        30         40        50  

               70        80        90       100       110       120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
       :. ::::::.::.:::.:::.:::::::::::::::::::::::  ::::.:.:::::.:
NP_001 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
             60        70        80        90       100       110  

              130       140       150       160       170       180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
       .::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
NP_001 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
            120       130       140       150       160       170  

              190       200       210       220       230       240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
         ::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
NP_001 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
            180       190       200       210       220       230  

              250       260       270            280       290     
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
       .::.::::::: ::::::.:.. :.::  .: .:     .:  :.: . :  :  ::.::
NP_001 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
            240       250         260       270        280         

         300       310       320       330       340       350     
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
       .:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
NP_001 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
     290       300       310       320       330       340         

         360       370       380       390       400       410     
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
       ::::::::::::::::::.::::::::  :.      .    :.:. :.:::. :     
NP_001 NSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQSRC--
     350       360       370       380       390        400        

         420       430        440    
pF1KB7 NISKLSEQVVLTSIST-LPAANGAGPLQNW
       .:::.::.:::::..: ::           
NP_001 SISKISEHVVLTSVTTVLP           
        410       420                

>>XP_016856596 (OMIM: 602392) PREDICTED: orexin receptor  (389 aa)
 initn: 1705 init1: 1261 opt: 1746  Z-score: 1666.9  bits: 317.4 E(85289): 4.2e-86
Smith-Waterman score: 1746; 70.9% identity (87.0% similar) in 368 aa overlap (24-385:17-378)

               10        20        30        40        50        60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
                              ..::   : ::.:: :::::::.::.::.:::::::.
XP_016        MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
                      10        20        30         40        50  

               70        80        90       100       110       120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
       :. ::::::.::.:::.:::.:::::::::::::::::::::::  ::::.:.:::::.:
XP_016 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
             60        70        80        90       100       110  

              130       140       150       160       170       180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
       .::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
XP_016 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
            120       130       140       150       160       170  

              190       200       210       220       230       240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
         ::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
XP_016 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
            180       190       200       210       220       230  

              250       260       270            280       290     
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
       .::.::::::: ::::::.:.. :.::  .: .:     .:  :.: . :  :  ::.::
XP_016 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
            240       250         260       270        280         

         300       310       320       330       340       350     
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
       .:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
XP_016 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
     290       300       310       320       330       340         

         360       370       380        390       400       410    
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSC-CCLGVHHRQEDRLTRGRTSTESRKSLTTQISNF
       ::::::::::::::   .: . :.::  : :                             
XP_016 NSAANPIIYNFLSGC--KEKSLALSCPSCPGHDPHLAAALCS                  
     350       360         370       380                           

          420       430       440    
pF1KB7 DNISKLSEQVVLTSISTLPAANGAGPLQNW

>>NP_444264 (OMIM: 607449) neuropeptide FF receptor 2 is  (420 aa)
 initn: 605 init1: 419 opt: 530  Z-score: 514.8  bits: 104.3 E(85289): 6.2e-22
Smith-Waterman score: 658; 32.1% identity (59.9% similar) in 377 aa overlap (8-379:6-348)

               10        20        30        40        50        60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
              :.   .::    ..:.:.. . .  .     .. :    :::  .   ..: .
NP_444   MNEKWDTNSSENWHPIWNVNDTKHHLYSDINIT---YVNY----YLHQPQVAAIFIIS
                 10        20        30               40        50 

               70        80        90       100       110       120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
       :...: . ..::..::  : .:.::.:::: ::.::...:.:: : :.: ::. .:   :
NP_444 YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGW
              60        70        80        90       100       110 

              130       140       150       160       170       180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
        ::...::.   .: .::..::.::  ::.::.  . .:.  : : : :   :.:::...
NP_444 PFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLA
             120       130       140       150       160       170 

              190            200       210       220       230     
pF1KB7 CIIMIPQAIVMECST-----VFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAP
         :: :.:.... .      :  .  :::.    : : : .. . :.:   .:   :.::
NP_444 ITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAP
             180       190       200       210       220       230 

         240       250       260       270       280       290     
pF1KB7 LCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQ
       : :.:. : .:  .:.   .: :.   :..:   . ::                      
NP_444 LSLIVIMYGRIGISLFRAAVPHTGRKNQEQW---HVVS----------------------
             240       250       260                               

         300       310       320       330       340       350     
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
        : ..:  .::.:: :.: . .::.  : .:.    .  .  .  ..:  . :.:::...
NP_444 -RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAFG
         270       280       290       300       310        320    

         360       370       380       390       400       410     
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
       ::..:::::.:.. .::. :. ::                                    
NP_444 NSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQEST
          330       340       350       360       370       380    

>>NP_001138228 (OMIM: 607449) neuropeptide FF receptor 2  (423 aa)
 initn: 605 init1: 419 opt: 530  Z-score: 514.7  bits: 104.3 E(85289): 6.2e-22
Smith-Waterman score: 658; 32.1% identity (59.9% similar) in 377 aa overlap (8-379:9-351)

                10        20        30        40        50         
pF1KB7  MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIA
               :.   .::    ..:.:.. . .  .     .. :    :::  .   ..: 
NP_001 MFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINIT---YVNY----YLHQPQVAAIFII
               10        20        30           40            50   

      60        70        80        90       100       110         
pF1KB7 GYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET
       .:...: . ..::..::  : .:.::.:::: ::.::...:.:: : :.: ::. .:   
NP_001 SYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAG
            60        70        80        90       100       110   

     120       130       140       150       160       170         
pF1KB7 WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIV
       : ::...::.   .: .::..::.::  ::.::.  . .:.  : : : :   :.:::..
NP_001 WPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVL
           120       130       140       150       160       170   

     180       190            200       210       220       230    
pF1KB7 SCIIMIPQAIVMECST-----VFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMA
       .  :: :.:.... .      :  .  :::.    : : : .. . :.:   .:   :.:
NP_001 AITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLA
           180       190       200       210       220       230   

          240       250       260       270       280       290    
pF1KB7 PLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIK
       :: :.:. : .:  .:.   .: :.   :..:   . ::                     
NP_001 PLSLIVIMYGRIGISLFRAAVPHTGRKNQEQW---HVVS---------------------
           240       250       260                                 

          300       310       320       330       340       350    
pF1KB7 QIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVY
         : ..:  .::.:: :.: . .::.  : .:.    .  .  .  ..:  . :.:::..
NP_001 --RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAF
       270       280       290       300       310        320      

          360       370       380       390       400       410    
pF1KB7 ANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNF
       .::..:::::.:.. .::. :. ::                                   
NP_001 GNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQES
        330       340       350       360       370       380      

>>NP_004876 (OMIM: 607449) neuropeptide FF receptor 2 is  (522 aa)
 initn: 605 init1: 419 opt: 530  Z-score: 513.8  bits: 104.5 E(85289): 7e-22
Smith-Waterman score: 658; 32.1% identity (59.9% similar) in 377 aa overlap (8-379:108-450)

                                      10        20        30       
pF1KB7                        MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDE
                                     :.   .::    ..:.:.. . .  .    
NP_004 RTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINIT--
        80        90       100       110       120       130       

        40        50        60        70        80        90       
pF1KB7 EFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLS
        .. :    :::  .   ..: .:...: . ..::..::  : .:.::.:::: ::.::.
NP_004 -YVNY----YLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLA
              140       150       160       170       180       190

       100       110       120       130       140       150       
pF1KB7 LADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAIC
       ..:.:: : :.: ::. .:   : ::...::.   .: .::..::.::  ::.::.  . 
NP_004 ISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVV
              200       210       220       230       240       250

       160       170       180       190            200       210  
pF1KB7 HPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECST-----VFPGLANKTTLFTVCDE
       .:.  : : : :   :.:::...  :: :.:.... .      :  .  :::.    : :
NP_004 YPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCRE
              260       270       280       290       300       310

            220       230       240       250       260       270  
pF1KB7 RWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPV
        : .. . :.:   .:   :.::: :.:. : .:  .:.   .: :.   :..:   . :
NP_004 DWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQW---HVV
              320       330       340       350       360          

            280       290       300       310       320       330  
pF1KB7 SQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGM
       :                       : ..:  .::.:: :.: . .::.  : .:.    .
NP_004 S-----------------------RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADL
                              370       380       390       400    

            340       350       360       370       380       390  
pF1KB7 FAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQED
         .  .  ..:  . :.:::...::..:::::.:.. .::. :. ::             
NP_004 SPNELQIINIYI-YPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPME
          410        420       430       440       450       460   

            400       410       420       430       440           
pF1KB7 RLTRGRTSTESRKSLTTQISNFDNISKLSEQVVLTSISTLPAANGAGPLQNW       
                                                                  
NP_004 AYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
           470       480       490       500       510       520  

>>NP_071429 (OMIM: 607448) neuropeptide FF receptor 1 [H  (430 aa)
 initn: 583 init1: 399 opt: 491  Z-score: 477.7  bits: 97.5 E(85289): 7.2e-20
Smith-Waterman score: 652; 34.9% identity (58.7% similar) in 375 aa overlap (10-379:8-344)

               10         20        30        40        50         
pF1KB7 MSGTKLEDSPPCRNWS-SASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIA
                ::  .:  : .  :    :  : :      :  :    : : .    ..:.
NP_071   MEGEPSQPPNSSWPLSQNGTNTEATPATNLT------FSSY----YQHTSPVAAMFIV
                 10        20        30                  40        

      60        70        80        90       100       110         
pF1KB7 GYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET
       .: ..:.. ..::.:::  : ::.::.::::.::.::...:.:: : :.:.::: ..   
NP_071 AYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITG
       50        60        70        80        90       100        

     120       130       140       150       160       170         
pF1KB7 WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIV
       : : .. ::.   .: .:::.::.::  ::..:.  : ::.  : : ..:  .:..:: .
NP_071 WPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWAL
      110       120       130       140       150       160        

     180       190           200       210       220       230     
pF1KB7 SCIIMIPQAIVM----ECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAP
       . .:: :.:...    :    .    :..  .  : : :  . . ..:   .:   :.::
NP_071 ALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAP
      170       180       190       200       210       220        

         240       250       260       270       280       290     
pF1KB7 LCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQ
       : :.:. : .: ::: : : :: .                  ::       .  ::. . 
NP_071 LALIVVMYARIARKL-C-QAPGPA------------------PG-------GEEAADPRA
      230       240         250                                260 

         300       310       320       330       340       350     
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
        : : ....::..: : :.. .::.  : .:     . :      :::: : :.:::.. 
NP_071 SRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYA-FPFAHWLAFF
             270       280       290       300       310        320

         360       370       380       390       400       410     
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
       ::.::::::.... .::. :.:::                                    
NP_071 NSSANPIIYGYFNENFRRGFQAAFRARLCPRPSGSHKEAYSERPGGLLHRRVFVVVRPSD
              330       340       350       360       370       380




444 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 05:41:05 2016 done: Fri Nov  4 05:41:06 2016
 Total Scan time:  8.710 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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