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SpecieshumanProduct IDFXC03780Cloning SiteSgfI-PmeIGeneKIBB6115SymbolSLC6A3
Alias : DAT, DAT1, PKDYS, PKDYS1Descriptionsolute carrier family 6 (neurotransmitter transporter), member 3Original Clone IDcs00715
Length: 1860 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 620 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS3863.1 0 100.0 SLC6A3 CCDS10754.1 1e-187 67.0 SLC6A2 CCDS54011.1 1.8e-185 66.9 SLC6A2 CCDS58463.1 7.5e-148 66.8 SLC6A2 CCDS11256.1 3.2e-134 49.9 SLC6A4
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR002436 1 16 PR01202 Sodium:neurotransmitter symporter IPR002436 17 30 PR01202 Sodium:neurotransmitter symporter IPR002436 42 59 PR01202 Sodium:neurotransmitter symporter IPR000175 68 89 PR00176 Sodium:neurotransmitter symporter IPR000175 97 116 PR00176 Sodium:neurotransmitter symporter IPR000175 140 166 PR00176 Sodium:neurotransmitter symporter IPR000175 265 282 PR00176 Sodium:neurotransmitter symporter IPR000175 347 367 PR00176 Sodium:neurotransmitter symporter IPR000175 401 420 PR00176 Sodium:neurotransmitter symporter IPR000175 481 501 PR00176 Sodium:neurotransmitter symporter IPR000175 521 541 PR00176 Sodium:neurotransmitter symporter IPR002436 540 550 PR01202 Sodium:neurotransmitter symporter HMMPfam IPR000175 60 582 PF00209 Sodium:neurotransmitter symporter ProfileScan IPR000175 59 585 PS50267 Sodium:neurotransmitter symporter
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 67 IDFLLSVIGFAVDLANVWRFPYL 89 SECONDARY 23 2 98 FLVPYLLFMVIAGMPLFYMELAL 120 PRIMARY 23 3 137 ILKGVGFTVILISLYVGFFYNVI 159 PRIMARY 23 4 240 LTACLVLVIVLLYFSLWKGVKTS 262 PRIMARY 23 5 265 VVWITATMPYVVLTALLLRGVTL 287 PRIMARY 23 6 309 SVWIDAATQVCFSLGVGFGVLIA 331 SECONDARY 23 7 353 NSLTSFSSGFVVFSFLGYMAQKH 375 SECONDARY 23 8 398 IATLPLSSAWAVVFFIMLLTLGI 420 SECONDARY 23 9 450 LFIVLATFLLSLFCVTNGGIYVF 472 PRIMARY 23 10 482 TSILFGVLIEAIGVAWFYGVGQF 504 PRIMARY 23 11 523 CWKLVSPCFLLFVVVVSIVTFR 544 PRIMARY 22 12 556 WANALGWVIATSSMAMVPIYAAY 578 PRIMARY 23
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_001035 620 126455,188890,613135 100.0 100.0 NP_001165972 617 163970,604715 67.0 98.4 NP_001034 617 163970,604715 67.0 98.4 NP_001165975 628 163970,604715 66.9 97.6 XP_011521597 628 163970,604715 66.9 97.6 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB6115 Download>KIBB6115 1860 bp ATGAGTAAGAGCAAATGCTCCGTGGGACTCATGTCTTCCGTGGTGGCCCCGGCTAAGGAG CCCAATGCCGTGGGCCCGAAGGAGGTGGAGCTCATCCTTGTCAAGGAGCAGAACGGAGTG CAGCTCACCAGCTCCACCCTCACCAACCCGCGGCAGAGCCCCGTGGAGGCCCAGGATCGG GAGACCTGGGGCAAGAAGATCGACTTTCTCCTGTCCGTCATTGGCTTTGCTGTGGACCTG GCCAACGTCTGGCGGTTCCCCTACCTGTGCTACAAAAATGGTGGCGGTGCCTTCCTGGTC CCCTACCTGCTCTTCATGGTCATTGCTGGGATGCCACTTTTCTACATGGAGCTGGCCCTC GGCCAGTTCAACAGGGAAGGGGCCGCTGGTGTCTGGAAGATCTGCCCCATACTGAAAGGT GTGGGCTTCACGGTCATCCTCATCTCACTGTATGTCGGCTTCTTCTACAACGTCATCATC GCCTGGGCGCTGCACTATCTCTTCTCCTCCTTCACCACGGAGCTCCCCTGGATCCACTGC AACAACTCCTGGAACAGCCCCAACTGCTCGGATGCCCATCCTGGTGACTCCAGTGGAGAC AGCTCGGGCCTCAACGACACTTTTGGGACCACACCTGCTGCCGAGTACTTTGAACGTGGC GTGCTGCACCTCCACCAGAGCCATGGCATCGACGACCTGGGGCCTCCGCGGTGGCAGCTC ACAGCCTGCCTGGTGCTGGTCATCGTGCTGCTCTACTTCAGCCTCTGGAAGGGCGTGAAG ACCTCAGGGAAGGTGGTATGGATCACAGCCACCATGCCATACGTGGTCCTCACTGCCCTG CTCCTGCGTGGGGTCACCCTCCCTGGAGCCATAGACGGCATCAGAGCATACCTGAGCGTT GACTTCTACCGGCTCTGCGAGGCGTCTGTTTGGATTGACGCGGCCACCCAGGTGTGCTTC TCCCTGGGCGTGGGGTTCGGGGTGCTGATCGCCTTCTCCAGCTACAACAAGTTCACCAAC AACTGCTACAGGGACGCGATTGTCACCACCTCCATCAACTCCCTGACGAGCTTCTCCTCC GGCTTCGTCGTCTTCTCCTTCCTGGGGTACATGGCACAGAAGCACAGTGTGCCCATCGGG GACGTGGCCAAGGACGGGCCAGGGCTGATCTTCATCATCTACCCGGAAGCCATCGCCACG CTCCCTCTGTCCTCAGCCTGGGCCGTGGTCTTCTTCATCATGCTGCTCACCCTGGGTATC GACAGCGCCATGGGTGGTATGGAGTCAGTGATCACCGGGCTCATCGATGAGTTCCAGCTG CTGCACAGACACCGTGAGCTCTTCACGCTCTTCATCGTCCTGGCGACCTTCCTCCTGTCC CTGTTCTGCGTCACCAACGGTGGCATCTACGTCTTCACGCTCCTGGACCATTTTGCAGCC GGCACGTCCATCCTCTTTGGAGTGCTCATCGAAGCCATCGGAGTGGCCTGGTTCTATGGT GTTGGGCAGTTCAGCGACGACATCCAGCAGATGACCGGGCAGCGGCCCAGCCTGTACTGG CGGCTGTGCTGGAAGCTGGTCAGCCCCTGCTTTCTCCTGTTCGTGGTCGTGGTCAGCATT GTGACCTTCAGACCCCCCCACTACGGAGCCTACATCTTCCCCGACTGGGCCAACGCGCTG GGCTGGGTCATCGCCACATCCTCCATGGCCATGGTGCCCATCTATGCGGCCTACAAGTTC TGCAGCCTGCCTGGGTCCTTTCGAGAGAAACTGGCCTACGCCATTGCACCCGAGAAGGAC CGTGAGCTGGTGGACAGAGGGGAGGTGCGCCAGTTCACGCTCCGCCACTGGCTCAAGGTG
Cloned ORF protein sequence for pF1KB6115 Download>KIBB6115 620 aa MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDR ETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL GQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHC NNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQL TACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSV DFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSS GFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGI DSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAA GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSI VTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKD RELVDRGEVRQFTLRHWLKV
Nucleotide Sequence (with vector) for pF1KB6115 Download>pF1KB6115 4973 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGAGTAAGAGC AAATGCTCCGTGGGACTCATGTCTTCCGTGGTGGCCCCGGCTAAGGAGCCCAATGCCGTG GGCCCGAAGGAGGTGGAGCTCATCCTTGTCAAGGAGCAGAACGGAGTGCAGCTCACCAGC TCCACCCTCACCAACCCGCGGCAGAGCCCCGTGGAGGCCCAGGATCGGGAGACCTGGGGC AAGAAGATCGACTTTCTCCTGTCCGTCATTGGCTTTGCTGTGGACCTGGCCAACGTCTGG CGGTTCCCCTACCTGTGCTACAAAAATGGTGGCGGTGCCTTCCTGGTCCCCTACCTGCTC TTCATGGTCATTGCTGGGATGCCACTTTTCTACATGGAGCTGGCCCTCGGCCAGTTCAAC AGGGAAGGGGCCGCTGGTGTCTGGAAGATCTGCCCCATACTGAAAGGTGTGGGCTTCACG GTCATCCTCATCTCACTGTATGTCGGCTTCTTCTACAACGTCATCATCGCCTGGGCGCTG CACTATCTCTTCTCCTCCTTCACCACGGAGCTCCCCTGGATCCACTGCAACAACTCCTGG AACAGCCCCAACTGCTCGGATGCCCATCCTGGTGACTCCAGTGGAGACAGCTCGGGCCTC AACGACACTTTTGGGACCACACCTGCTGCCGAGTACTTTGAACGTGGCGTGCTGCACCTC CACCAGAGCCATGGCATCGACGACCTGGGGCCTCCGCGGTGGCAGCTCACAGCCTGCCTG GTGCTGGTCATCGTGCTGCTCTACTTCAGCCTCTGGAAGGGCGTGAAGACCTCAGGGAAG GTGGTATGGATCACAGCCACCATGCCATACGTGGTCCTCACTGCCCTGCTCCTGCGTGGG GTCACCCTCCCTGGAGCCATAGACGGCATCAGAGCATACCTGAGCGTTGACTTCTACCGG CTCTGCGAGGCGTCTGTTTGGATTGACGCGGCCACCCAGGTGTGCTTCTCCCTGGGCGTG GGGTTCGGGGTGCTGATCGCCTTCTCCAGCTACAACAAGTTCACCAACAACTGCTACAGG GACGCGATTGTCACCACCTCCATCAACTCCCTGACGAGCTTCTCCTCCGGCTTCGTCGTC TTCTCCTTCCTGGGGTACATGGCACAGAAGCACAGTGTGCCCATCGGGGACGTGGCCAAG GACGGGCCAGGGCTGATCTTCATCATCTACCCGGAAGCCATCGCCACGCTCCCTCTGTCC TCAGCCTGGGCCGTGGTCTTCTTCATCATGCTGCTCACCCTGGGTATCGACAGCGCCATG GGTGGTATGGAGTCAGTGATCACCGGGCTCATCGATGAGTTCCAGCTGCTGCACAGACAC CGTGAGCTCTTCACGCTCTTCATCGTCCTGGCGACCTTCCTCCTGTCCCTGTTCTGCGTC ACCAACGGTGGCATCTACGTCTTCACGCTCCTGGACCATTTTGCAGCCGGCACGTCCATC CTCTTTGGAGTGCTCATCGAAGCCATCGGAGTGGCCTGGTTCTATGGTGTTGGGCAGTTC AGCGACGACATCCAGCAGATGACCGGGCAGCGGCCCAGCCTGTACTGGCGGCTGTGCTGG AAGCTGGTCAGCCCCTGCTTTCTCCTGTTCGTGGTCGTGGTCAGCATTGTGACCTTCAGA CCCCCCCACTACGGAGCCTACATCTTCCCCGACTGGGCCAACGCGCTGGGCTGGGTCATC GCCACATCCTCCATGGCCATGGTGCCCATCTATGCGGCCTACAAGTTCTGCAGCCTGCCT GGGTCCTTTCGAGAGAAACTGGCCTACGCCATTGCACCCGAGAAGGACCGTGAGCTGGTG GACAGAGGGGAGGTGCGCCAGTTCACGCTCCGCCACTGGCTCAAGGTGGTTTAAACGAAT TCGAGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGATCCGGC TGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATAACTAGC ATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGGAGGAACTAT ATCCGGTTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCATGTAAGCCCACT GCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCAGTAGCT GACATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTGTTCCGCTTCCT TTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAAGAATTGCCAGCT GGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATGGCTTTCTTGCCG CCAAGGATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGATGACGGTCGTTT CGCATGCTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGGGTGGAGAGGCTA TTCGGCTATGACTGGGCACAACAGACAATCGGCTGCTCTGATGCCGCCGTGTTCCGGCTG TCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGTGCCCTGAATGAA CTGCAGGACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTTCCTTGCGCAGCT GTGCTCGACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGCGAAGTGCCGGGG CAGGATCTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATCATGGCTGATGCA ATGCGGCGGCTGCATACGCTTGATCCGGCTACCTGCCCATTCGACCACCAAGCGAAACAT CGCATCGAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAGGATGATCTGGAC GAAGAGCATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAGGCGCGTATGCCG GATGGTGAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAATATCATGGTGGAA AATGGCCGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCGGACCGCTATCAG GACATAGCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAATGGGCTGACCGC TTCCTCGTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCCTTCTATCGCCTT CTTGACGAGTTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACCAAGCGACGCCCA ACCGGTATCAGCTCACTCAAAGGCGGTAATACGGTTATCCACAGAATCAGGGGATAACGC AGGAAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGCCGCGTT GCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAG TCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTC CCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCC TTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGT CGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTT ATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACTGGCAGC AGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGTTCTTGAA GTGGTGGCCTAACTACGGCTACACTAGAAGGACAGTATTTGGTATCTGCGCTCTGCTGAA GCCAGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGG TAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAAAGGATTTCAAGA AGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAGG GATTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTATAGTCCGGAAA TACAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAATGGCAGC TTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTATTCATAC GGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCATTTTTAC CTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAGGGATTAT GGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACTCCGGCCA CGATGCGTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACAGATTAAATCAGAACG CAGAAGCGGTCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGTGGTCCCACCTGA CCCCATGCCGAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGTGGGGTCTCCCCA TGCGAGAGTAGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGTCGAAAGACTGGG CCTTTCGTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGACAAATCCGCCGG GAGCGGATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAGGACGCCCGCCAT AAACTGCCAGGCATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCCTTTTTGCGTTTC TACAAACTCTTTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCAT
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