Gene/Protein Characteristic Table for FHC02645

Species
human

Product ID
FHC02645

Corresponding
Flexi Clone PID

ORF Sequence
DNA sequence (1356 bp)
Protein sequence (452 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB463785]

Gene
KIBB8187

Symbol
ILK
Alias : ILK-2, P59

Description
integrin-linked kinase

Original Clone ID
cp00547

Quality control data of this clone

Characterization of the cloned ORF

N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand

Features of the cloned ORF sequence

Length: 1356 bp
Restriction map A Restriction map B
Features of the protein sequence

Length: 452 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
Q13418 6.4e-186 100.0 Integrin-linked...
Homo sapiens
AAX42665 6.4e-186 100.0 integrin-linked...
synthetic construct
XP_534040 1.3e-185 99.7 similar to inte...
Canis lupus fam...
Q99J82 2.3e-185 99.5 Integrin-linked...
Rattus norvegicus
Q5R5V4 4.7e-185 99.5 Integrin-linked...
Pongo abelii

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PD000001 PR01415 PR01415 PF00023 PF00023 PF00023 PF07714 SM00248 SM00248 SM00248 SM00219 SM00220 PS50297 PS50088 PS50088 PS50088 PS50011

Result of InterProScan

Search method interpro_ID From To Entry Definition
BlastProDom IPR000719 205 450 PD000001 Protein kinase
FPrintScan IPR002110 67 79 PR01415 Ankyrin
IPR002110 79 91 PR01415 Ankyrin
HMMPfam IPR002110 33 65 PF00023 Ankyrin
IPR002110 66 98 PF00023 Ankyrin
IPR002110 99 131 PF00023 Ankyrin
IPR001245 193 446 PF07714 Tyrosine protein kinase
HMMSmart IPR002110 33 62 SM00248 Ankyrin
IPR002110 66 95 SM00248 Ankyrin
IPR002110 99 128 SM00248 Ankyrin
IPR001245 193 446 SM00219 Tyrosine protein kinase
IPR002290 193 446 SM00220 Serine/threonine protein kinase
ProfileScan IPR002110 26 140 PS50297 Ankyrin
IPR002110 33 65 PS50088 Ankyrin
IPR002110 66 98 PS50088 Ankyrin
IPR002110 99 131 PS50088 Ankyrin
IPR000719 193 446 PS50011 Protein kinase

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_001014795 452 602366 100.0 100.0
NP_004508 452 602366 100.0 100.0
NP_001014794 452 602366 100.0 100.0
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