Gene/Protein Characteristic Table for FHC00635

Species
human

Clone Name

Product ID
FHC00635

Corresponding
Flexi Clone PID

ORF Sequence
DNA sequence (3141 bp)
Protein sequence (1047 aa)

Linker Type
Flexi_RBS type
The extra Tyr-Val-Val codons are attached to the 3'-end of the ORF, because ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB383988]

Gene

Symbol
KDM4C
Alias : GASC1, JHDM3C, JMJD2C, TDRD14C, bA146B14.1

Description
lysine (K)-specific demethylase 4C, transcript variant 2

Original Clone ID

Quality control data of this clone

Characterization of the cloned ORF

N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand

Features of the cloned ORF sequence

Length: 3141 bp
Restriction map A Restriction map B
Features of the protein sequence

Length: 1047 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
BAG09844 0 100.0 jmjC domain-con...
synthetic construct
BAA34500 0 100.0 KIAA0780 protei...
Homo sapiens
NP_001140166 0 99.9 lysine-specific...
Homo sapiens
EAW58730 0 99.5 jumonji domain ...
Homo sapiens
NP_055876 0 99.7 lysine-specific...
Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PF02375 PF02373 SM00545 SM00558 SM00249 SM00249 SM00333 SM00333 PS51183 PS51184

Result of InterProScan

Search method interpro_ID From To Entry Definition
HMMPfam IPR003349 17 62 PF02375 Transcription factor jumonji
IPR013129 177 293 PF02373 Transcription factor jumonji
HMMSmart IPR003349 15 57 SM00545 Transcription factor jumonji
IPR003347 144 310 SM00558 Transcription factor jumonji/aspartyl beta-hydroxylase
IPR001965 689 747 SM00249 Zinc finger
IPR001965 809 865 SM00249 Zinc finger
IPR002999 877 934 SM00333 Tudor
IPR002999 935 991 SM00333 Tudor
ProfileScan IPR003349 16 58 PS51183 Transcription factor jumonji
IPR003347 144 310 PS51184 Transcription factor jumonji/aspartyl beta-hydroxylase

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_055876 1056 605469 99.9 95.6
NP_055830 1096 609765 76.4 94.7
NP_055478 1064 609764 77.0 95.3
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