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SpecieshumanProduct IDFXC11937Cloning SiteSgfI-PmeIGeneKIBB3324SymbolBTRC
Alias : BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCPDescriptionbeta-transducin repeat containing E3 ubiquitin protein ligase, transcript variant 1Original Clone IDcs03071
Length: 1815 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 605 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS7512.1 4.1e-197 100.0 BTRC CCDS7511.1 6.7e-180 94.0 BTRC CCDS73183.1 5.5e-171 95.7 BTRC CCDS34289.1 1.2e-143 76.2 FBXW11 CCDS47340.1 1.5e-142 86.7 FBXW11
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR020472 356 370 PR00320 G-protein beta WD-40 repeat IPR020472 479 493 PR00320 G-protein beta WD-40 repeat IPR020472 519 533 PR00320 G-protein beta WD-40 repeat HMMPfam IPR021977 138 177 PF12125 D domain of beta-TrCP IPR001810 192 229 PF00646 F-box domain IPR019781 304 329 PF00400 WD40 repeat IPR019781 334 369 PF00400 WD40 repeat IPR019781 374 409 PF00400 WD40 repeat IPR019781 420 452 PF00400 WD40 repeat IPR019781 457 492 PF00400 WD40 repeat IPR019781 497 532 PF00400 WD40 repeat IPR019781 547 581 PF00400 WD40 repeat HMMSmart IPR001810 189 228 SM00256 F-box domain IPR001680 292 329 SM00320 WD40 repeat IPR001680 332 369 SM00320 WD40 repeat IPR001680 372 409 SM00320 WD40 repeat IPR001680 415 452 SM00320 WD40 repeat IPR001680 455 492 SM00320 WD40 repeat IPR001680 495 532 SM00320 WD40 repeat IPR001680 544 581 SM00320 WD40 repeat ProfileScan IPR001810 190 228 PS50181 F-box domain IPR017986 299 590 PS50294 WD40-repeat-containing domain IPR019782 312 329 PS50082 WD40 repeat 2 IPR019782 339 378 PS50082 WD40 repeat 2 IPR019782 379 418 PS50082 WD40 repeat 2 IPR019782 422 461 PS50082 WD40 repeat 2 IPR019782 462 501 PS50082 WD40 repeat 2 IPR019782 502 533 PS50082 WD40 repeat 2 IPR019782 551 590 PS50082 WD40 repeat 2
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_378663 605 603482 100.0 100.0 XP_006718117 732 603482 100.0 97.4 XP_016872361 587 603482 100.0 97.0 XP_016872362 587 603482 100.0 97.0 XP_016872360 587 603482 100.0 97.0 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB3324 Download>KIBB3324 1815 bp ATGGACCCGGCCGAGGCGGTGCTGCAAGAGAAGGCACTCAAGTTTATGTGCTCTATGCCC AGGTCTCTGTGGCTGGGCTGCTCCAGCCTGGCGGACAGCATGCCTTCGCTGCGATGCCTG TATAACCCAGGGACTGGCGCACTCACAGCTTTCCAGAATTCCTCAGAGAGAGAAGACTGT AATAATGGCGAACCCCCTAGGAAGATAATACCAGAGAAGAATTCACTTAGACAGACATAC AACAGCTGTGCCAGACTCTGCTTAAACCAAGAAACAGTATGTTTAGCAAGCACTGCTATG AAGACTGAGAATTGTGTGGCCAAAACAAAACTTGCCAATGGCACTTCCAGTATGATTGTG CCCAAGCAACGGAAACTCTCAGCAAGCTATGAAAAGGAAAAGGAACTGTGTGTCAAATAC TTTGAGCAGTGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATATCCCAAATG TGTCATTACCAACATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTC ATAACTGCTCTGCCAGCTCGGGGATTGGATCATATTGCTGAGAACATTCTGTCATACCTG GATGCCAAATCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAGTGACCTCT GATGGCATGCTGTGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGA GGCCTGGCAGAACGAAGAGGATGGGGACAGTATTTATTCAAAAACAAACCTCCTGACGGG AATGCTCCTCCCAACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAGACATTGAG ACAATAGAATCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGT GAAACAAGCAAAGGAGTTTACTGTTTACAGTATGATGATCAGAAAATAGTAAGCGGCCTT CGAGACAACACAATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAATTCTCACA GGCCATACAGGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCA TCGGATTCCACGGTCAGAGTGTGGGATGTAAATACAGGTGAAATGCTAAACACGTTGATT CACCATTGTGAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGACCTGCTCC AAAGATCGTTCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGG GTGCTGGTCGGACACCGAGCTGCTGTCAATGTTGTAGACTTTGATGACAAGTACATTGTT TCTGCATCTGGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAATTTGTAAGG ACCTTAAATGGACACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTG AGTGGCTCATCTGACAACACTATCAGATTATGGGACATAGAATGTGGTGCATGTTTACGA GTGTTAGAAGGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGAGGATAGTC AGTGGGGCCTATGATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGT GCTCCTGCAGGGACACTCTGTCTACGGACCCTTGTGGAGCATTCCGGAAGAGTTTTTCGA CTACAGTTTGATGAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCCTCATCTGG GACTTCCTAAATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATAC ACCTACATCTCCAGA
Cloned ORF protein sequence for pF1KB3324 Download>KIBB3324 605 aa MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY TYISR
Nucleotide Sequence (with vector) for pF1KB3324 Download>pF1KB3324 4928 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGGACCCGGCC GAGGCGGTGCTGCAAGAGAAGGCACTCAAGTTTATGTGCTCTATGCCCAGGTCTCTGTGG CTGGGCTGCTCCAGCCTGGCGGACAGCATGCCTTCGCTGCGATGCCTGTATAACCCAGGG ACTGGCGCACTCACAGCTTTCCAGAATTCCTCAGAGAGAGAAGACTGTAATAATGGCGAA CCCCCTAGGAAGATAATACCAGAGAAGAATTCACTTAGACAGACATACAACAGCTGTGCC AGACTCTGCTTAAACCAAGAAACAGTATGTTTAGCAAGCACTGCTATGAAGACTGAGAAT TGTGTGGCCAAAACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGG AAACTCTCAGCAAGCTATGAAAAGGAAAAGGAACTGTGTGTCAAATACTTTGAGCAGTGG TCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATATCCCAAATGTGTCATTACCAA CATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTG CCAGCTCGGGGATTGGATCATATTGCTGAGAACATTCTGTCATACCTGGATGCCAAATCA CTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAGTGACCTCTGATGGCATGCTG TGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAA CGAAGAGGATGGGGACAGTATTTATTCAAAAACAAACCTCCTGACGGGAATGCTCCTCCC AACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAGACATTGAGACAATAGAATCT AATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGTGAAACAAGCAAA GGAGTTTACTGTTTACAGTATGATGATCAGAAAATAGTAAGCGGCCTTCGAGACAACACA ATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAATTCTCACAGGCCATACAGGT TCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCCACG GTCAGAGTGTGGGATGTAAATACAGGTGAAATGCTAAACACGTTGATTCACCATTGTGAA GCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGACCTGCTCCAAAGATCGTTCC ATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGA CACCGAGCTGCTGTCAATGTTGTAGACTTTGATGACAAGTACATTGTTTCTGCATCTGGG GATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAATTTGTAAGGACCTTAAATGGA CACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCT GACAACACTATCAGATTATGGGACATAGAATGTGGTGCATGTTTACGAGTGTTAGAAGGC CATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGAGGATAGTCAGTGGGGCCTAT GATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGG ACACTCTGTCTACGGACCCTTGTGGAGCATTCCGGAAGAGTTTTTCGACTACAGTTTGAT GAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCCTCATCTGGGACTTCCTAAAT GATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATACACCTACATCTCC AGAGTTTAAACGAATTCGAGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCAT GCAAGCTGATCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGC TGAGCAATAACTAGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCT GAAAGGAGGAACTATATCCGGTTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCG CCATGTAAGCCCACTGCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCA GATAGCCCAGTAGCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTA CGTGTTCCGCTTCCTTTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCA AAAGAATTGCCAGCTGGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGG ATGGCTTTCTTGCCGCCAAGGATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAGACA GGATGACGGTCGTTTCGCATGCTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCT TGGGTGGAGAGGCTATTCGGCTATGACTGGGCACAACAGACAATCGGCTGCTCTGATGCC GCCGTGTTCCGGCTGTCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCC GGTGCCCTGAATGAACTGCAGGACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGC GTTCCTTGCGCAGCTGTGCTCGACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTG GGCGAAGTGCCGGGGCAGGATCTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCC ATCATGGCTGATGCAATGCGGCGGCTGCATACGCTTGATCCGGCTACCTGCCCATTCGAC CACCAAGCGAAACATCGCATCGAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGAT CAGGATGATCTGGACGAAGAGCATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTC AAGGCGCGTATGCCGGATGGTGAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCG AATATCATGGTGGAAAATGGCCGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTG GCGGACCGCTATCAGGACATAGCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGC GAATGGGCTGACCGCTTCCTCGTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATC GCCTTCTATCGCCTTCTTGACGAGTTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCG ACCAAGCGACGCCCAACCGGTATCAGCTCACTCAAAGGCGGTAATACGGTTATCCACAGA ATCAGGGGATAACGCAGGAAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCG TAAAAAGGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAA AAATCGACGCTCAAGTCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTT TCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCT GTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCT CAGTTCGGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCC CGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACTT ATCGCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGC TACAGAGTTCTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGGACAGTATTTGGTAT CTGCGCTCTGCTGAAGCCAGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAA ACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAA AAAAGGATTTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGA AAACTCACGTTAAGGGATTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCT TTTATAGTCCGGAAATACAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACC ATGAAAAATGGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTG CATAGGTATTCATACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTT TGTTGCCATTTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTA CAATTAAGGGATTATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACC GCAGTACTCCGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACA GATTAAATCAGAACGCAGAAGCGGTCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGC GGTGGTCCCACCTGACCCCATGCCGAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAG TGTGGGGTCTCCCCATGCGAGAGTAGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTC AGTCGAAAGACTGGGCCTTTCGTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTA GGACAAATCCGCCGGGAGCGGATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGG CAGGACGCCCGCCATAAACTGCCAGGCATCAAATTAAGCAGAAGGCCATCCTGACGGATG GCCTTTTTGCGTTTCTACAAACTCTTTTGTTTATTTTTCTAAATACATTCAAATATGTAT CCGCTCAT
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