HUGE

Gene/Protein Characteristic Table for KIAA0037

Link to : GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00380
Accession No. :	D25538
Description :	Adenylate cyclase type 7.
HUGO Gene Name :	adenylate cyclase 7 (ADCY7)
Clone Name :	ha00929 [Vector Info]
Flexi ORF Clone :	pF1KSDA0037
Source :	Myeloblast cell line (KG-1)

Features of the cloned DNA sequence	Description

Length: 6196 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 2688 bp

Genome contig ID gi51511732f_48779327
PolyA signal sequence
(ATTAAA,-25)
+----*----+----*----+----*----+----
CTTTTTATACATTAAATTAGCAATTTGAAAAACTC
Flanking genome sequence
(130219 - 130268)
----+----*----+----*----+----*----+----*----+----*
AAATATCTGAAGGTATTTTATTTTCGTGGTCCTCATGAACTCACTAGAGA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 16 f 48879327 48909544 26 100.0 Internal No-hit

Features of the protein sequence	Description

Length: 1088 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
P51828	100.0	Adenylate cycla...	Homo sapiens
CAA89894	85.9	adenylyl cyclas...	Bos taurus
S68685	85.3	65 kda antigen ...	Mycobacterium g...
Q29450	85.2	Adenylate cycla...	Bos taurus
XP_001056453	84.2	similar to Aden...	Rattus norvegicus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB028983	5.3e-168	58.7	KIAA1060
AB011083	8.7e-70	37.4	KIAA0511
AB007882	6.8e-40	39.5	KIAA0422
AB011092	3.1e-27	30.4	KIAA0520

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR001054 278 462 PF00211 Adenylyl cyclase class-3/4/guanylyl cyclase

IPR009398 476 601 PF06327 Adenylate cyclase-like

IPR001054 878 1077 PF00211 Adenylyl cyclase class-3/4/guanylyl cyclase

HMMSmart IPR001054 232 440 SM00044 Adenylyl cyclase class-3/4/guanylyl cyclase

IPR001054 848 1060 SM00044 Adenylyl cyclase class-3/4/guanylyl cyclase

ProfileScan IPR001054 287 414 PS50125 Adenylyl cyclase class-3/4/guanylyl cyclase

IPR001054 887 1031 PS50125 Adenylyl cyclase class-3/4/guanylyl cyclase

ScanRegExp IPR001054 1008 1031 PS00452 Adenylyl cyclase class-3/4/guanylyl cyclase

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR001054	278	462	PF00211	Adenylyl cyclase class-3/4/guanylyl cyclase
IPR009398	476	601	PF06327	Adenylate cyclase-like
IPR001054	878	1077	PF00211	Adenylyl cyclase class-3/4/guanylyl cyclase
HMMSmart	IPR001054	232	440	SM00044	Adenylyl cyclase class-3/4/guanylyl cyclase
IPR001054	848	1060	SM00044	Adenylyl cyclase class-3/4/guanylyl cyclase
ProfileScan	IPR001054	287	414	PS50125	Adenylyl cyclase class-3/4/guanylyl cyclase
IPR001054	887	1031	PS50125	Adenylyl cyclase class-3/4/guanylyl cyclase
ScanRegExp	IPR001054	1008	1031	PS00452	Adenylyl cyclase class-3/4/guanylyl cyclase

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 40 GPLLLTLLLVAATACVALIIIAF 62 PRIMARY 23

2 73 ILGMAFLVLAVFAALSVLMYVEC 95 PRIMARY 23

3 101 LRALALLTWACLVALGYVLVFDA 123 PRIMARY 23

4 143 VVYTLLPFSMRGAVAVGAVSTAS 165 PRIMARY 23

5 182 VRVGLQLLANAVIFLCGNLTGAF 204 SECONDARY 23

6 603 HDFACASLIFVCILLVHVLLMPR 625 PRIMARY 23

7 630 GVSFGLVACVLGLVLGLCFATKF 652 PRIMARY 23

8 673 PLLRLTLAVLTIGSLLTVAIINL 695 SECONDARY 23

9 740 ACSVFLRMSLEPKVVLLTVALVA 762 PRIMARY 23

10 804 KTMTNFYLVLFYITLLTLSRQID 826 SECONDARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	40	GPLLLTLLLVAATACVALIIIAF	62	PRIMARY	23
2	73	ILGMAFLVLAVFAALSVLMYVEC	95	PRIMARY	23
3	101	LRALALLTWACLVALGYVLVFDA	123	PRIMARY	23
4	143	VVYTLLPFSMRGAVAVGAVSTAS	165	PRIMARY	23
5	182	VRVGLQLLANAVIFLCGNLTGAF	204	SECONDARY	23
6	603	HDFACASLIFVCILLVHVLLMPR	625	PRIMARY	23
7	630	GVSFGLVACVLGLVLGLCFATKF	652	PRIMARY	23
8	673	PLLRLTLAVLTIGSLLTVAIINL	695	SECONDARY	23
9	740	ACSVFLRMSLEPKVVLLTVALVA	762	PRIMARY	23
10	804	KTMTNFYLVLFYITLLTLSRQID	826	SECONDARY	23

Expression profile	Description

: Northern blot Description

Northern blot	Description

RH mapping information	Description

Chromosome No.

: 16

Experimental conditions

Panel name	: Stanford G3
Primer_f	: ATGACCAAACTGCCCGTGACT
Primer_r	: ATTTTCGTTCCCTCCACCGCC
PCR product length	: 317 bp
PCR conditions	: 95 °C15 sec64 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	2688 bp
Genome contig ID	gi51511732f_48779327
PolyA signal sequence (ATTAAA,-25)	+--------+--------+----*----+---- CTTTTTATACATTAAATTAGCAATTTGAAAAACTC
Flanking genome sequence (130219 - 130268)	----+--------+--------+--------+--------+----* AAATATCTGAAGGTATTTTATTTTCGTGGTCCTCATGAACTCACTAGAGA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	16	f	48879327	48909544	26	100.0	Internal No-hit

Gene/Protein Characteristic Table for KIAA0037

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information