Gene/Protein Characteristic Table for KIAA1346
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Product ID ORK00218
Accession No AB037767
Description ADAM metallopeptidase with thrombospondin type 1 motif, 1
Clone name fj00671
Vector information
The cDNA fragment was inserted at the SalI-NotI site of the ...
cDNA sequence DNA sequence (4309 bp)
Predicted protein sequence (999 aa)
Flexi ORF Clone FXC00218
Source Human fetal brain
Rouge ID mKIAA1346 by Kazusa Mouse cDNA Project
Features of the cloned cDNA sequence
Description

Length: 4309 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis).

N-terminal truncation Coding interruption
cloned DNA seq No warning No warning
Integrity of 3' end
Length of 3'UTR 1290 bp
Genome contig ID gi51511750r_27030479
PolyA signal sequence
(AATAAA,-19)
+----*----+----*----+----*----+----
AATATATGTTACTAGAAATAAAAGAACACTTTTGG
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AATGTGTGTGTCTGTTTTTTGAAGTGGGAATTCATTCCTAGGAAGGAAAC

Ensembl ContigView (Add our DAS server as a DAS source)


Chr f/r start end exon identity class
Ensembl gnome browser 21 r 27130479 27139259 9 99.8 Perfect prediction
Features of the protein sequence
Description

Length: 999 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
BAG11309 0 100.0 ADAM metallopep...
synthetic construct
CAI46043 0 99.9 hypothetical pr...
Homo sapiens
AAF15317 0 99.8 metalloproteina...
Homo sapiens
AAH36515 0 99.9 ADAM metallopep...
Homo sapiens
Q9UHI8 0 99.9 A disintegrin a...
Homo sapiens
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against HUGE database (FASTA output, Multiple alignment)
Entry Exp ID% HUGE_ID
AB014588 2.1e-129 49.8 KIAA0688
AB037733 2.9e-109 39.9 KIAA1312
AB002364 3.1e-67 31.5 KIAA0366
AB095949 6.1e-47 34.9 KIAA2029
AB011177 6.8e-22 29.9 KIAA0605
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR013274 33 51 PR01858 Peptidase M12B
IPR013274 134 145 PR01858 Peptidase M12B
IPR013274 196 208 PR01858 Peptidase M12B
IPR013274 226 240 PR01858 Peptidase M12B
IPR013274 345 356 PR01858 Peptidase M12B
IPR013273 600 618 PR01857 Peptidase M12B
IPR013274 646 655 PR01858 Peptidase M12B
IPR013273 717 736 PR01857 Peptidase M12B
IPR013273 737 756 PR01857 Peptidase M12B
IPR013274 959 975 PR01858 Peptidase M12B
HMMPfam IPR002870 66 205 PF01562 Peptidase M12B
IPR001590 290 499 PF01421 Peptidase M12B
IPR000884 595 645 PF00090 Thrombospondin
IPR010294 757 875 PF05986 ADAM-TS Spacer 1
IPR000884 888 941 PF00090 Thrombospondin
IPR000884 947 998 PF00090 Thrombospondin
HMMSmart IPR006586 500 580 SM00608 ADAM
IPR000884 594 646 SM00209 Thrombospondin
IPR000884 889 942 SM00209 Thrombospondin
IPR000884 943 999 SM00209 Thrombospondin
ProfileScan IPR001590 290 499 PS50215 Peptidase M12B
IPR000884 591 646 PS50092 Thrombospondin
IPR000884 886 937 PS50092 Thrombospondin
IPR000884 940 999 PS50092 Thrombospondin
ScanRegExp IPR006025 430 439 PS00142 Peptidase M
IPR001128 524 533 PS00086 Cytochrome P450
Expression profile
Description

RT-PCR-ELISA
Experimental conditions
Primer_f CCCTGTTTCCTGGTACTTATC
Primer_r CCATAGCAGCCATAAACAGTG
PCR conditions 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RH mapping information
Description

Chromosome No. 21
Experimental conditions
Panel name unigene
Primer_f -
Primer_r -
PCR product length -
PCR conditions -
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