Gene/Protein Characteristic Table for KIAA1312
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Product ID ORK04046
Accession No AB037733
Description ADAM metallopeptidase with thrombospondin type 1 motif, 9
Clone name fh11767
Vector information
The cDNA fragment was inserted at the SalI-NotI site of the ...
cDNA sequence DNA sequence (5139 bp)
Predicted protein sequence (1471 aa)
Source Human fetal brain
Rouge ID mKIAA1312 by Kazusa Mouse cDNA Project
Features of the cloned cDNA sequence
Description

Length: 5139 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis).

N-terminal truncation Coding interruption
cloned DNA seq Warning No warning
Integrity of 3' end
Length of 3'UTR 722 bp
Genome contig ID gi89161205r_64410865
PolyA signal sequence
(AATAAA,-20)
+----*----+----*----+----*----+----
ACCCTTTTTAATGGTAATAAACCAGTAGTAATCAT
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AGCATGATTATATTATTTTCAAACATCGTAATATGTTCATATCTGTATGA

Ensembl ContigView (Add our DAS server as a DAS source)


Chr f/r start end exon identity class
Ensembl gnome browser 3 r 64510865 64647326 30 99.8 Perfect prediction
Features of the protein sequence
Description

Length: 1471 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
Q9P2N4 0 100.0 A disintegrin a...
Homo sapiens
AAO15765 0 99.9 a disintegrin-l...
Homo sapiens
XP_528704 0 99.6 ADAM metallopep...
Pan troglodytes
XP_001091856 0 99.3 similar to ADAM...
Macaca mulatta
XP_001488010 0 93.9 ADAM metallopep...
Equus caballus
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against HUGE database (FASTA output, Multiple alignment)
Entry Exp ID% HUGE_ID
AB037767 2.9e-107 39.8 KIAA1346
AB014588 2e-92 46.0 KIAA0688
AB095949 1.6e-85 33.5 KIAA2029
AB002364 1.6e-72 32.5 KIAA0366
AB018305 5.8e-13 26.3 KIAA0762
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR013273 439 457 PR01857 Peptidase M12B
IPR013273 555 574 PR01857 Peptidase M12B
IPR013273 575 594 PR01857 Peptidase M12B
HMMPfam IPR002870 5 49 PF01562 Peptidase M12B
IPR001590 135 341 PF01421 Peptidase M12B
IPR000884 434 484 PF00090 Thrombospondin
IPR010294 595 713 PF05986 ADAM-TS Spacer 1
IPR000884 841 895 PF00090 Thrombospondin
IPR000884 898 950 PF00090 Thrombospondin
IPR000884 953 976 PF00090 Thrombospondin
IPR000884 1026 1051 PF00090 Thrombospondin
IPR000884 1089 1137 PF00090 Thrombospondin
IPR000884 1174 1225 PF00090 Thrombospondin
IPR000884 1228 1281 PF00090 Thrombospondin
IPR000884 1287 1322 PF00090 Thrombospondin
IPR000884 1346 1367 PF00090 Thrombospondin
IPR000884 1404 1454 PF00090 Thrombospondin
HMMSmart IPR000884 433 485 SM00209 Thrombospondin
IPR000884 723 778 SM00209 Thrombospondin
IPR000884 780 828 SM00209 Thrombospondin
IPR000884 842 896 SM00209 Thrombospondin
IPR000884 897 946 SM00209 Thrombospondin
IPR000884 952 1008 SM00209 Thrombospondin
IPR000884 1028 1082 SM00209 Thrombospondin
IPR000884 1084 1138 SM00209 Thrombospondin
IPR000884 1174 1226 SM00209 Thrombospondin
IPR000884 1227 1282 SM00209 Thrombospondin
IPR000884 1286 1341 SM00209 Thrombospondin
IPR000884 1343 1397 SM00209 Thrombospondin
IPR000884 1400 1455 SM00209 Thrombospondin
ProfileScan IPR001590 135 341 PS50215 Peptidase M12B
IPR000884 430 485 PS50092 Thrombospondin
IPR000884 720 778 PS50092 Thrombospondin
IPR000884 839 896 PS50092 Thrombospondin
IPR000884 897 946 PS50092 Thrombospondin
IPR000884 949 1008 PS50092 Thrombospondin
IPR000884 1024 1082 PS50092 Thrombospondin
IPR000884 1083 1138 PS50092 Thrombospondin
IPR000884 1170 1221 PS50092 Thrombospondin
IPR000884 1224 1282 PS50092 Thrombospondin
IPR000884 1283 1336 PS50092 Thrombospondin
IPR000884 1339 1397 PS50092 Thrombospondin
IPR000884 1398 1455 PS50092 Thrombospondin
ScanRegExp IPR006025 273 282 PS00142 Peptidase M
Expression profile
Description

RT-PCR-ELISA
Experimental conditions
Primer_f GTAACCATCGTCAGCTCAGCC
Primer_r CAGTTCACAGTGGCAAATCGG
PCR conditions 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RH mapping information
Description

Chromosome No. 3
Experimental conditions
Panel name GeneBridge 4
Primer_f GTAACCATCGTCAGCTCAGCC
Primer_r CAGTTCACAGTGGCAAATCGG
PCR product length 113 bp
PCR conditions 95 °C15 sec66 °C60 sec30 cycles
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