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SpecieshumanProduct IDFXC04167Cloning SiteSgfI-PmeIGenBank AccessionSymbolARHGEF6
Alias : COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIXDescriptionRac/Cdc42 guanine nucleotide exchange factor (GEF) 6, transcript variant 1NoteWe obtained this clone using the E.coli strain Stbl2 at 37 deg C.
Length: 2328 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 776 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS14660.1 4.5e-191 100.0 ARHGEF6 CCDS78509.1 2e-152 100.0 ARHGEF6 CCDS32009.1 1.3e-72 59.0 ARHGEF7 CCDS86360.1 1.4e-72 56.2 ARHGEF7 CCDS45068.1 5.6e-72 57.3 ARHGEF7
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR003096 31 46 PR00888 Smooth muscle protein/calponin IPR003096 78 93 PR00888 Smooth muscle protein/calponin IPR003096 99 113 PR00888 Smooth muscle protein/calponin IPR001452 177 192 PR00452 Src homology-3 domain IPR001452 194 203 PR00452 Src homology-3 domain IPR001452 205 217 PR00452 Src homology-3 domain HMMPfam IPR001715 3 105 PF00307 Calponin homology domain IPR011511 165 217 PF07653 Variant SH3 IPR000219 245 419 PF00621 Dbl homology (DH) domain IPR001849 461 547 PF00169 Pleckstrin homology domain HMMSmart IPR001715 3 106 SM00033 Calponin homology domain IPR001452 163 218 SM00326 Src homology-3 domain IPR000219 245 420 SM00325 Dbl homology (DH) domain IPR001849 450 550 SM00233 Pleckstrin homology domain ProfileScan IPR001715 1 110 PS50021 Calponin homology domain IPR001452 160 219 PS50002 Src homology-3 domain IPR000219 241 421 PS50010 Dbl homology (DH) domain IPR001849 443 548 PS50003 Pleckstrin homology domain
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_004831 776 300267 100.0 100.0 XP_011529715 780 300267 99.5 100.0 XP_011529716 773 300267 98.6 100.0 NP_001293106 622 300267 100.0 80.2 XP_005262556 727 300267 93.7 100.0 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KA0006 Download>KIAA0006 2328 bp ATGAATCCAGAAGAACAAATCGTGACATGGCTTATATCTTTGGGAGTTTTAGAGTCCCCT AAAAAGACCATCTGTGATCCGGAGGAGTTTTTAAAGTCCTCGCTGAAAAATGGGGTAGTT CTGTGCAAACTGATCAACAGACTCATGCCTGGCTCTGTGGAAAAGTTTTGTCTGGATCCC CAAACTGAAGCTGACTGCATCAACAACATCAATGACTTCCTGAAAGGATGTGCAACCCTC CAAGTGGAAATATTTGATCCTGATGACCTTTATTCAGGGGTCAATTTCTCCAAGGTACTG AGTACTCTTTTAGCTGTCAACAAAGCAACAGAAGATCAGCTATCAGAAAGACCATGTGGA CGTTCCTCTTCTCTTAGTGCTGCTAATACTTCTCAGACAAACCCACAGGGAGCAGTTTCT AGCACAGTTTCAGGGCTGCAAAGGCAGTCAAAGACAGTGGAGATGACGGAAAATGGAAGT CATCAGTTGATAGTAAAAGCAAGATTCAACTTTAAGCAGACTAATGAGGATGAACTGTCA GTTTGTAAGGGGGACATCATTTACGTCACACGAGTTGAAGAAGGAGGCTGGTGGGAAGGC ACATTAAATGGGAGAACAGGCTGGTTCCCCAGTAATTATGTCCGTGAAATTAAATCCAGT GAGAGACCTCTCTCCCCAAAAGCCGTCAAAGGATTTGAAACTGCTCCACTTACCAAGAAT TATTATACTGTGGTGTTACAGAACATCCTGGACACTGAAAAAGAATATGCTAAAGAACTT CAGTCTCTTCTTGTTACTTACTTAAGACCCCTGCAGTCCAATAACAATCTGAGTACTGTG GAGGTTACATCTTTACTGGGAAACTTCGAGGAAGTATGCACATTTCAACAGACACTCTGC CAAGCCTTGGAAGAATGTTCAAAGTTTCCAGAAAACCAGCACAAAGTAGGAGGTTGTCTA CTGAGTCTCATGCCTCATTTTAAATCTATGTATCTGGCTTACTGTGCAAACCATCCTTCA GCTGTAAATGTGCTCACTCAGCACAGTGATGAGTTGGAACAATTCATGGAAAATCAAGGT GCATCGAGCCCAGGTATCCTCATTTTAACAACAAACCTCAGCAAACCATTCATGCGACTG GAGAAATATGTTACTCTCTTGCAAGAGTTAGAACGGCATATGGAGGATACTCATCCAGAT CATCAGGATATTCTGAAAGCAATCGTAGCATTCAAAACTCTCATGGGGCAATGTCAAGAT CTGAGGAAGAGAAAACAGCTGGAGTTACAGATACTGTCCGAACCTATTCAGGCATGGGAA GGAGAAGATATTAAAAACTTGGGAAATGTGATTTTTATGTCACAAGTAATGGTGCAGTAT GGAGCATGTGAGGAAAAAGAGGAGCGGTACCTTATGTTATTTTCAAATGTCCTGATAATG TTATCTGCAAGTCCTCGGATGAGTGGCTTTATCTATCAGGGAAAAATACCAATAGCAGGA ACGGTGGTGACTAGATTAGATGAAATTGAAGGGAATGACTGCACATTTGAAATCACTGGT AACACAGTGGAGAGAATTGTGGTCCATTGTAACAACAACCAGGACTTCCAGGAATGGTTG GAGCAGCTGAACAGACTGATCAGAGGACCTGCCTCTTGCAGTTCATTATCCAAAACCTCA TCGTCATCATGTAGTGCTCATTCTTCTTTTAGCTCTACCGGACAGCCCCGAGGACCCTTG GAGCCTCCTCAAATTATAAAACCGTGGAGTTTAAGTTGTCTACGACCTGCACCTCCACTT AGACCATCAGCAGCACTAGGTTATAAAGAGAGGATGTCTTATATCTTAAAGGAGTCTAGT AAAAGCCCTAAAACGATGAAGAAATTTCTTCATAAAAGGAAGACTGAGAGAAAACCATCG GAGGAGGAATATGTGATTAGGAAAAGTACAGCTGCTCTGGAAGAGGATGCTCAAATCCTT AAAGTGATCGAAGCCTACTGCACCAGCGCAAATTTTCAACAAGGCCATGGCTCAAGTACT CGAAAAGATTCCATTCCACAAGTCCTACTCCCTGAGGAAGAGAAACTCATCATTGAAGAA ACCAGAAGCAACGGCCAGACCATCATGGAAGAAAAGAGCCTTGTTGATACTGTTTACGCC TTGAAGGACGAGGTCAGAGAACTGAAGCAGGAAAATAAAAGAATGAAGCAATGCCTGGAA GAAGAACTGAAATCAAGAAGGGACCTAGAAAAGCTGGTGCGGAGGCTTTTGAAGCAAACA GATGAGTGTATTCGAGGCGAGTCCAGTAGCAAGACCTCAATTCTTCCA
Cloned ORF protein sequence for pF1KA0006 Download>KIAA0006 776 aa MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL EQLNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPL RPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQIL KVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYA LKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
Nucleotide Sequence (with vector) for pF1KA0006 Download>pF1KA0006 5441 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGAATCCAGAA GAACAAATCGTGACATGGCTTATATCTTTGGGAGTTTTAGAGTCCCCTAAAAAGACCATC TGTGATCCGGAGGAGTTTTTAAAGTCCTCGCTGAAAAATGGGGTAGTTCTGTGCAAACTG ATCAACAGACTCATGCCTGGCTCTGTGGAAAAGTTTTGTCTGGATCCCCAAACTGAAGCT GACTGCATCAACAACATCAATGACTTCCTGAAAGGATGTGCAACCCTCCAAGTGGAAATA TTTGATCCTGATGACCTTTATTCAGGGGTCAATTTCTCCAAGGTACTGAGTACTCTTTTA GCTGTCAACAAAGCAACAGAAGATCAGCTATCAGAAAGACCATGTGGACGTTCCTCTTCT CTTAGTGCTGCTAATACTTCTCAGACAAACCCACAGGGAGCAGTTTCTAGCACAGTTTCA GGGCTGCAAAGGCAGTCAAAGACAGTGGAGATGACGGAAAATGGAAGTCATCAGTTGATA GTAAAAGCAAGATTCAACTTTAAGCAGACTAATGAGGATGAACTGTCAGTTTGTAAGGGG GACATCATTTACGTCACACGAGTTGAAGAAGGAGGCTGGTGGGAAGGCACATTAAATGGG AGAACAGGCTGGTTCCCCAGTAATTATGTCCGTGAAATTAAATCCAGTGAGAGACCTCTC TCCCCAAAAGCCGTCAAAGGATTTGAAACTGCTCCACTTACCAAGAATTATTATACTGTG GTGTTACAGAACATCCTGGACACTGAAAAAGAATATGCTAAAGAACTTCAGTCTCTTCTT GTTACTTACTTAAGACCCCTGCAGTCCAATAACAATCTGAGTACTGTGGAGGTTACATCT TTACTGGGAAACTTCGAGGAAGTATGCACATTTCAACAGACACTCTGCCAAGCCTTGGAA GAATGTTCAAAGTTTCCAGAAAACCAGCACAAAGTAGGAGGTTGTCTACTGAGTCTCATG CCTCATTTTAAATCTATGTATCTGGCTTACTGTGCAAACCATCCTTCAGCTGTAAATGTG CTCACTCAGCACAGTGATGAGTTGGAACAATTCATGGAAAATCAAGGTGCATCGAGCCCA GGTATCCTCATTTTAACAACAAACCTCAGCAAACCATTCATGCGACTGGAGAAATATGTT ACTCTCTTGCAAGAGTTAGAACGGCATATGGAGGATACTCATCCAGATCATCAGGATATT CTGAAAGCAATCGTAGCATTCAAAACTCTCATGGGGCAATGTCAAGATCTGAGGAAGAGA AAACAGCTGGAGTTACAGATACTGTCCGAACCTATTCAGGCATGGGAAGGAGAAGATATT AAAAACTTGGGAAATGTGATTTTTATGTCACAAGTAATGGTGCAGTATGGAGCATGTGAG GAAAAAGAGGAGCGGTACCTTATGTTATTTTCAAATGTCCTGATAATGTTATCTGCAAGT CCTCGGATGAGTGGCTTTATCTATCAGGGAAAAATACCAATAGCAGGAACGGTGGTGACT AGATTAGATGAAATTGAAGGGAATGACTGCACATTTGAAATCACTGGTAACACAGTGGAG AGAATTGTGGTCCATTGTAACAACAACCAGGACTTCCAGGAATGGTTGGAGCAGCTGAAC AGACTGATCAGAGGACCTGCCTCTTGCAGTTCATTATCCAAAACCTCATCGTCATCATGT AGTGCTCATTCTTCTTTTAGCTCTACCGGACAGCCCCGAGGACCCTTGGAGCCTCCTCAA ATTATAAAACCGTGGAGTTTAAGTTGTCTACGACCTGCACCTCCACTTAGACCATCAGCA GCACTAGGTTATAAAGAGAGGATGTCTTATATCTTAAAGGAGTCTAGTAAAAGCCCTAAA ACGATGAAGAAATTTCTTCATAAAAGGAAGACTGAGAGAAAACCATCGGAGGAGGAATAT GTGATTAGGAAAAGTACAGCTGCTCTGGAAGAGGATGCTCAAATCCTTAAAGTGATCGAA GCCTACTGCACCAGCGCAAATTTTCAACAAGGCCATGGCTCAAGTACTCGAAAAGATTCC ATTCCACAAGTCCTACTCCCTGAGGAAGAGAAACTCATCATTGAAGAAACCAGAAGCAAC GGCCAGACCATCATGGAAGAAAAGAGCCTTGTTGATACTGTTTACGCCTTGAAGGACGAG GTCAGAGAACTGAAGCAGGAAAATAAAAGAATGAAGCAATGCCTGGAAGAAGAACTGAAA TCAAGAAGGGACCTAGAAAAGCTGGTGCGGAGGCTTTTGAAGCAAACAGATGAGTGTATT CGAGGCGAGTCCAGTAGCAAGACCTCAATTCTTCCAGTTTAAACGAATTCGAGCTCGGTA CCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGATCCGGCTGCTAACAAAGC CCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATAACTAGCATAACCCCTTGG GGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGGAGGAACTATATCCGGTTCGCT TGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCATGTAAGCCCACTGCAAGCTACCTG CTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCAGTAGCTGACATTCATCCG GGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTGTTCCGCTTCCTTTAGCAGCCCTT GCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAAGAATTGCCAGCTGGGGCGCCCTCT GGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATGGCTTTCTTGCCGCCAAGGATCTGA TGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGATGACGGTCGTTTCGCATGCTTGAA CAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGGGTGGAGAGGCTATTCGGCTATGAC TGGGCACAACAGACAATCGGCTGCTCTGATGCCGCCGTGTTCCGGCTGTCAGCGCAGGGG CGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGTGCCCTGAATGAACTGCAGGACGAG GCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTTCCTTGCGCAGCTGTGCTCGACGTT GTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGCGAAGTGCCGGGGCAGGATCTCCTG TCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATCATGGCTGATGCAATGCGGCGGCTG CATACGCTTGATCCGGCTACCTGCCCATTCGACCACCAAGCGAAACATCGCATCGAGCGA GCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAGGATGATCTGGACGAAGAGCATCAG GGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAGGCGCGTATGCCGGATGGTGAGGAT CTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAATATCATGGTGGAAAATGGCCGCTTT TCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCGGACCGCTATCAGGACATAGCGTTG GCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAATGGGCTGACCGCTTCCTCGTGCTT TACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCCTTCTATCGCCTTCTTGACGAGTTC TTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACCAAGCGACGCCCAACCGGTATCAGC TCACTCAAAGGCGGTAATACGGTTATCCACAGAATCAGGGGATAACGCAGGAAAGAACAT GTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGCCGCGTTGCTGGCGTTTTT CCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCAGAGGTGGCG AAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGTGCGCTC TCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGT GGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCGTTCGCTCCAA GCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTA TCGTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACTGGCAGCAGCCACTGGTAA CAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGTTCTTGAAGTGGTGGCCTAA CTACGGCTACACTAGAAGGACAGTATTTGGTATCTGCGCTCTGCTGAAGCCAGTTACCTT CGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTAGCGGTGGTTT TTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAAAGGATTTCAAGAAGATCCTTTGAT CTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAGGGATTTTGGTCAT GAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTATAGTCCGGAAATACAGGAACGCA CGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAATGGCAGCTTCAGTGGATTA AGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTATTCATACGGTTAAAATTTA TCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCATTTTTACCTGTCTGCTGCC GTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAGGGATTATGGTAAATCCACT TACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACTCCGGCCACGATGCGTCCGG CGTAGAGGATCGAGATCTTTTCAGCCTGATACAGATTAAATCAGAACGCAGAAGCGGTCT GATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGTGGTCCCACCTGACCCCATGCCGAA CTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGTGGGGTCTCCCCATGCGAGAGTAGG GAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGTCGAAAGACTGGGCCTTTCGTTTTA TCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGACAAATCCGCCGGGAGCGGATTTGA ACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAGGACGCCCGCCATAAACTGCCAGGC ATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCCTTTTTGCGTTTCTACAAACTCTTT TGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCAT
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