Gene/Protein Characteristic Table for KIAA1975
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Product ID ORK05737
Accession No AB075855
Description ankyrin repeat and GTPase domain Arf GTPase activating protein 11
Clone name aj01061
Vector information
The cDNA fragment was inserted at the SalI-NotI site of the ...
cDNA sequence DNA sequence (4559 bp)
Predicted protein sequence (597 aa)
Source Human brain (amygdala)
Features of the cloned cDNA sequence
Description

Length: 4559 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis).

N-terminal truncation Coding interruption
cloned DNA seq No warning Warning
Integrity of 3' end
Length of 3'UTR 298 bp
Genome contig ID gi89161187f_88642143
PolyA signal sequence
(AATATA,-21)
+----*----+----*----+----*----+----
ATAAGATGTGTGAAAATATATTTGAAAAAAAGTTC
Flanking genome sequence
(117799 - 117848)
----+----*----+----*----+----*----+----*----+----*
ATAAATATGCATTGATTTTTGTACATATGGCACCTCTTTTTCATTTTTAT

Ensembl ContigView (Add our DAS server as a DAS source)


Chr f/r start end exon identity class
Ensembl gnome browser 10 f 88742143 88759940 7 99.5 Perfect prediction
Features of the protein sequence
Description

Length: 597 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
EAW80309 1.8e-190 100.0 hCG1994053, iso...
Homo sapiens
XP_001082744 2.2e-172 82.2 similar to cent...
Macaca mulatta
NP_055729 3.4e-172 82.4 centaurin, gamm...
Homo sapiens
EAW71079 4e-172 82.2 centaurin, gamm...
Homo sapiens
AAL04172 9.7e-172 82.0 centaurin gamma...
Homo sapiens
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against HUGE database (FASTA output, Multiple alignment)
Entry Exp ID% HUGE_ID
AB029022 8.8e-128 82.0 KIAA1099
D79989 2.5e-52 48.5 KIAA0167
AB051503 5.4e-16 41.0 KIAA1716
AB033075 8.4e-16 31.4 KIAA1249
D26069 7.3e-15 31.6 KIAA0041
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR001164 387 406 PR00405 Arf GTPase activating protein
IPR001164 406 423 PR00405 Arf GTPase activating protein
IPR001164 427 448 PR00405 Arf GTPase activating protein
IPR002110 535 547 PR01415 Ankyrin
IPR002110 580 592 PR01415 Ankyrin
HMMPfam IPR001849 169 354 PF00169 Pleckstrin-like
IPR001164 375 495 PF01412 Arf GTPase activating protein
IPR002110 534 566 PF00023 Ankyrin
IPR002110 567 592 PF00023 Ankyrin
HMMSmart IPR001849 169 356 SM00233 Pleckstrin-like
IPR001164 375 495 SM00105 Arf GTPase activating protein
IPR002110 534 563 SM00248 Ankyrin
IPR002110 567 596 SM00248 Ankyrin
ProfileScan IPR001849 168 354 PS50003 Pleckstrin-like
IPR001164 375 495 PS50115 Arf GTPase activating protein
IPR002110 502 591 PS50297 Ankyrin
IPR002110 534 566 PS50088 Ankyrin
Expression profile
Description

RT-PCR-ELISA
Experimental conditions
Primer_f GCAGAGCCATCCCCATTAAAC
Primer_r TTCCTGGGACTTTGATGGTAG
PCR conditions 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RH mapping information
Description

Chromosome No. 10
Experimental conditions
Panel name genbank
Primer_f -
Primer_r -
PCR product length -
PCR conditions -
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