ROUGE

Gene/Protein Characteristic Table for mKIAA0946

Link to : HUGE \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK122406
Description :	Huntingtin-interacting protein 14.
Clone Name :	mbx00001 [Vector Info]
Source :	Mouse brain

Features of the cloned DNA sequence	Description

Length: 5491 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 4091 bp

Genome contig ID gi65524842r_110464631
PolyA signal sequence
(AATAAA,-17)
+----*----+----*----+----*----+----
TTGTAAAATATTAATCAAAATAAATATTGACTCTT
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AAATGTGGTGTCTGCTCAGTTCACTTAGAAAGACTGTAAAATAAAGATTC

Genomic structure deduced by Blast search against draft genome sequences
Comparison with the corresponding KIAA cDNA.

KIAA Alignment based on:

KIAA0946 DNA sequence, AA sequence, Physical map

KIAA	Alignment based on:
KIAA0946	DNA sequence, AA sequence, Physical map

Features of the protein sequence	Description

Coding region: 3..1400
Length: 465 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
XP_509231	7.4e-183	95.6	huntingtin inte...	Pan troglodytes
XP_001082309	7.5e-183	95.6	huntingtin inte...	Macaca mulatta
Q80TN5	1e-178	99.3	Palmitoyltransf...	Mus musculus
Q8IUH5	3.6e-177	98.1	Palmitoyltransf...	Homo sapiens
XP_614891	3.6e-177	97.9	similar to hunt...	Bos taurus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AK173111	1.2e-12	29.5	mKIAA1148
AB093299	1.9e-11	30.4	mKIAA1728
AK129327	2.9e-10	30.1	mKIAA1306
AK173070	3.6e-10	28.4	mKIAA0957
AK122478	5e-10	30.2	mKIAA1250

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR002110 160 172 PR01415 Ankyrin

IPR002110 172 184 PR01415 Ankyrin

HMMPfam IPR002110 125 157 PF00023 Ankyrin

IPR002110 159 191 PF00023 Ankyrin

IPR002110 192 224 PF00023 Ankyrin

IPR002110 225 258 PF00023 Ankyrin

IPR002110 260 292 PF00023 Ankyrin

HMMSmart IPR002110 125 154 SM00248 Ankyrin

IPR002110 159 188 SM00248 Ankyrin

IPR002110 192 221 SM00248 Ankyrin

IPR002110 225 255 SM00248 Ankyrin

IPR002110 260 289 SM00248 Ankyrin

ProfileScan IPR002110 100 313 PS50297 Ankyrin

IPR002110 125 157 PS50088 Ankyrin

IPR002110 159 191 PS50088 Ankyrin

IPR002110 192 224 PS50088 Ankyrin

IPR002110 225 258 PS50088 Ankyrin

IPR002110 260 292 PS50088 Ankyrin

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR002110	160	172	PR01415	Ankyrin
IPR002110	172	184	PR01415	Ankyrin
HMMPfam	IPR002110	125	157	PF00023	Ankyrin
IPR002110	159	191	PF00023	Ankyrin
IPR002110	192	224	PF00023	Ankyrin
IPR002110	225	258	PF00023	Ankyrin
IPR002110	260	292	PF00023	Ankyrin
HMMSmart	IPR002110	125	154	SM00248	Ankyrin
IPR002110	159	188	SM00248	Ankyrin
IPR002110	192	221	SM00248	Ankyrin
IPR002110	225	255	SM00248	Ankyrin
IPR002110	260	289	SM00248	Ankyrin
ProfileScan	IPR002110	100	313	PS50297	Ankyrin
IPR002110	125	157	PS50088	Ankyrin
IPR002110	159	191	PS50088	Ankyrin
IPR002110	192	224	PS50088	Ankyrin
IPR002110	225	258	PS50088	Ankyrin
IPR002110	260	292	PS50088	Ankyrin

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 13 35 GLALALALALRLAEPREAETLSP

340 362 KVMLGTPFLVIWLVGFIADLDID

364 386 WLIKGLMYGGVWATVQFLSKSFF

418 440 LNFLFIHLPFLANSVALFYNFGK

Method	From	To	amino acid sequence
SOSUI	13	35	GLALALALALRLAEPREAETLSP
340	362	KVMLGTPFLVIWLVGFIADLDID
364	386	WLIKGLMYGGVWATVQFLSKSFF
418	440	LNFLFIHLPFLANSVALFYNFGK

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	4091 bp
Genome contig ID	gi65524842r_110464631
PolyA signal sequence (AATAAA,-17)	+--------+--------+----*----+---- TTGTAAAATATTAATCAAAATAAATATTGACTCTT
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AAATGTGGTGTCTGCTCAGTTCACTTAGAAAGACTGTAAAATAAAGATTC

Gene/Protein Characteristic Table for mKIAA0946

Features of the cloned DNA sequence

Features of the protein sequence