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SpecieshumanProduct IDFXC00331Cloning SiteSgfI-PmeIGeneKIBB3816SymbolDSCAM
Alias : CHD2, CHD2-42, CHD2-52DescriptionDown syndrome cell adhesion molecule, transcript variant 1Original Clone IDfg03766
Length: 6036 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 2012 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS42929.1 0 100.0 DSCAM CCDS8384.1 0 60.9 DSCAML1 CCDS33790.1 1.4e-24 25.2 CNTN3 CCDS55153.1 6.3e-23 25.1 NRCAM CCDS54424.1 3e-21 23.3 TTN
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR013098 231 304 PF07679 Immunoglobulin I-set IPR013098 316 389 PF07679 Immunoglobulin I-set IPR013098 407 501 PF07679 Immunoglobulin I-set IPR013098 508 593 PF07679 Immunoglobulin I-set IPR013098 599 686 PF07679 Immunoglobulin I-set IPR013098 690 783 PF07679 Immunoglobulin I-set IPR013098 790 882 PF07679 Immunoglobulin I-set IPR003961 888 972 PF00041 Fibronectin IPR003961 987 1076 PF00041 Fibronectin IPR003961 1091 1177 PF00041 Fibronectin IPR003961 1191 1273 PF00041 Fibronectin IPR013098 1301 1376 PF07679 Immunoglobulin I-set IPR003961 1384 1462 PF00041 Fibronectin IPR003961 1485 1556 PF00041 Fibronectin HMMSmart IPR003598 37 109 SM00408 Immunoglobulin subtype 2 IPR003599 130 218 SM00409 Immunoglobulin subtype IPR003599 231 311 SM00409 Immunoglobulin subtype IPR003598 237 300 SM00408 Immunoglobulin subtype 2 IPR003596 241 295 SM00406 Immunoglobulin V-set IPR003599 320 403 SM00409 Immunoglobulin subtype IPR003598 326 392 SM00408 Immunoglobulin subtype 2 IPR003599 413 502 SM00409 Immunoglobulin subtype IPR003598 419 491 SM00408 Immunoglobulin subtype 2 IPR003599 510 594 SM00409 Immunoglobulin subtype IPR003598 516 582 SM00408 Immunoglobulin subtype 2 IPR003599 602 687 SM00409 Immunoglobulin subtype IPR003598 608 676 SM00408 Immunoglobulin subtype 2 IPR003599 696 785 SM00409 Immunoglobulin subtype IPR003598 702 773 SM00408 Immunoglobulin subtype 2 IPR003596 706 768 SM00406 Immunoglobulin V-set IPR003599 794 883 SM00409 Immunoglobulin subtype IPR003598 800 872 SM00408 Immunoglobulin subtype 2 IPR003961 885 969 SM00060 Fibronectin IPR003961 985 1073 SM00060 Fibronectin IPR003961 1088 1174 SM00060 Fibronectin IPR003961 1189 1270 SM00060 Fibronectin IPR003599 1292 1377 SM00409 Immunoglobulin subtype IPR003598 1301 1366 SM00408 Immunoglobulin subtype 2 IPR003596 1302 1361 SM00406 Immunoglobulin V-set IPR003961 1380 1460 SM00060 Fibronectin IPR003961 1477 1557 SM00060 Fibronectin ProfileScan IPR007110 125 216 PS50835 Immunoglobulin-like IPR007110 225 305 PS50835 Immunoglobulin-like IPR007110 313 401 PS50835 Immunoglobulin-like IPR007110 407 500 PS50835 Immunoglobulin-like IPR007110 504 592 PS50835 Immunoglobulin-like IPR007110 596 685 PS50835 Immunoglobulin-like IPR007110 690 783 PS50835 Immunoglobulin-like IPR007110 787 883 PS50835 Immunoglobulin-like IPR003961 885 978 PS50853 Fibronectin IPR003961 984 1082 PS50853 Fibronectin IPR003961 1088 1183 PS50853 Fibronectin IPR003961 1189 1279 PS50853 Fibronectin IPR007110 1285 1377 PS50835 Immunoglobulin-like IPR003961 1376 1470 PS50853 Fibronectin IPR003961 1476 1566 PS50853 Fibronectin
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 1594 KMLVTISCILVGVLLLFVLLLVV 1616 PRIMARY 23
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_001380 2012 602523 100.0 100.0 NP_001258463 1994 602523 99.1 100.0 XP_016883770 1776 602523 100.0 88.3 NP_065744 2113 611782 60.9 98.1 XP_011541220 1977 611782 60.5 93.6 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB3816 Download>KIBB3816 6036 bp ATGTGGATACTGGCTCTCTCCTTGTTCCAGAGCTTCGCGAATGTTTTCAGTGAAGACCTA CACTCCAGCCTCTACTTTGTCAATGCATCTCTGCAAGAGGTAGTGTTTGCCAGCACCACG GGGACTCTGGTGCCCTGCCCCGCAGCAGGCATCCCTCCTGTGACTCTCAGATGGTACCTA GCCACGGGCGAGGAGATCTACGATGTCCCCGGGATCCGCCACGTCCACCCCAACGGCACT CTCCAAATTTTCCCCTTCCCTCCTTCAAGCTTCAGTACCTTAATCCATGATAATACTTAT TATTGCACAGCTGAAAATCCTTCAGGGAAAATTAGAAGTCAGGATGTCCACATCAAGGCT GTTTTACGGGAGCCCTATACAGTCCGTGTGGAGGACCAGAAAACCATGAGAGGCAATGTT GCGGTCTTCAAGTGCATTATCCCCTCCTCGGTGGAGGCGTACATCACTGTCGTCTCATGG GAGAAAGACACTGTTTCACTTGTCTCAGGATCTAGATTTCTCATCACATCCACGGGAGCC TTGTATATTAAAGATGTACAGAATGAAGATGGATTGTATAACTACCGCTGCATCACGCGG CATCGATACACCGGAGAGACGAGGCAGAGCAACAGCGCCAGACTTTTTGTATCAGACCCA GCGAACTCAGCCCCATCCATACTGGATGGGTTTGAGCATCGCAAAGCCATGGCTGGGCAG CGTGTGGAGCTGCCTTGCAAAGCGCTCGGGCACCCTGAGCCAGATTACCGCTGGCTGAAG GACAACATGCCCCTGGAACTTTCAGGGAGGTTCCAGAAGACCGTGACGGGGCTGCTCATT GAGAACATTCGCCCCTCGGACTCAGGCAGCTATGTTTGTGAAGTGTCCAACAGATACGGA ACTGCTAAGGTGATAGGCCGCCTGTACGTGAAACAGCCACTGAAAGCCACCATCAGTCCC AGGAAGGTTAAAAGCAGCGTGGGTAGCCAAGTTTCCTTGTCCTGCAGCGTGACAGGAACT GAGGACCAGGAACTCTCCTGGTACCGCAATGGTGAAATCCTCAACCCTGGAAAAAATGTG AGGATCACAGGGATCAACCACGAAAACCTTATAATGGATCACATGGTCAAAAGTGACGGG GGCGCATACCAGTGCTTTGTGCGCAAGGACAAGCTGTCCGCTCAAGACTATGTGCAGGTG GTCCTTGAAGATGGAACTCCCAAAATTATTTCTGCCTTTAGTGAAAAGGTGGTGAGTCCA GCAGAGCCGGTTTCCCTTATGTGCAACGTGAAGGGAACACCTTTGCCCACGATCACGTGG ACCCTGGACGATGACCCGATTCTCAAGGGTGGCAGTCACCGCATCAGCCAGATGATCACG TCGGAGGGGAACGTGGTCAGCTACCTGAACATCTCCAGCTCCCAGGTCCGGGACGGGGGA GTCTACCGCTGCACTGCCAACAACTCGGCGGGAGTCGTCCTGTACCAGGCTCGAATAAAC GTAAGAGGGCCTGCAAGCATTCGACCAATGAAAAACATCACAGCAATAGCAGGACGGGAC ACATACATTCACTGTCGTGTGATTGGCTATCCGTATTACTCCATTAAATGGTACAAGAAC TCTAACCTGCTTCCTTTCAACCACCGCCAAGTGGCATTTGAGAACAATGGAACTCTTAAA CTTTCAGATGTGCAAAAGGAAGTGGACGAGGGGGAGTACACGTGCAACGTGTTGGTTCAA CCACAACTCTCCACCAGCCAGAGCGTCCACGTGACCGTGAAAGTTCCGCCTTTCATACAA CCCTTTGAGTTTCCAAGATTCTCCATTGGGCAGCGGGTCTTCATCCCCTGTGTTGTGGTC TCAGGGGACTTACCCATCACGATCACCTGGCAGAAGGATGGCCGGCCAATCCCTGGGAGC CTTGGGGTGACCATTGACAATATTGACTTCACGAGCTCCTTGAGGATTTCCAATCTCTCG CTCATGCACAATGGGAATTACACCTGCATAGCCCGGAATGAGGCCGCCGCTGTGGAGCAC CAAAGCCAGTTGATTGTCAGAGTTCCTCCCAAGTTTGTGGTTCAGCCACGGGACCAGGAC GGGATTTATGGCAAAGCAGTCATCCTCAATTGTTCTGCTGAGGGTTACCCTGTACCTACC ATCGTGTGGAAATTCTCTAAAGGTGCTGGGGTTCCCCAGTTCCAGCCAATTGCCCTAAAT GGCCGAATCCAAGTTCTCAGCAATGGGTCGTTGCTGATCAAGCATGTCGTGGAGGAAGAC AGTGGCTACTACCTCTGCAAGGTCAGCAACGATGTGGGCGCAGACGTCAGCAAGTCCATG TACCTCACGGTTAAAATTCCTGCGATGATAACATCCTATCCAAATACTACCCTGGCCACG CAGGGGCAGAAAAAGGAGATGAGCTGCACGGCGCATGGTGAGAAGCCCATTATAGTCCGC TGGGAGAAGGAGGACCGAATCATTAACCCTGAGATGGCCCGTTATCTTGTGTCCACCAAG GAGGTGGGAGAAGAGGTGATTTCTACTCTGCAGATTTTGCCAACTGTGAGAGAAGATTCT GGTTTCTTTTCCTGCCATGCTATTAATTCTTATGGGGAGGACCGTGGAATAATTCAGCTC ACAGTGCAAGAGCCCCCAGACCCTCCCGAAATTGAGATCAAAGATGTCAAAGCACGCACA ATTACGCTCAGGTGGACCATGGGGTTTGATGGAAACAGTCCCATCACAGGCTACGATATT GAATGCAAAAATAAATCAGACTCCTGGGATTCTGCTCAGAGAACCAAAGATGTTTCCCCT CAGCTGAACTCGGCCACCATCATTGATATCCACCCTTCCTCCACCTACAGCATCCGCATG TACGCCAAGAACCGGATTGGCAAGAGCGAGCCCAGCAACGAGCTCACCATCACGGCGGAC GAGGCAGCTCCTGATGGTCCACCTCAGGAAGTTCACCTGGAGCCTATATCATCTCAGAGC ATCAGGGTCACATGGAAGGCTCCCAAGAAACATTTGCAAAATGGGATTATCCGTGGCTAC CAAATAGGTTACCGAGAGTACAGCACTGGGGGTAACTTCCAATTCAACATTATCAGTGTC GACACCAGCGGGGACAGTGAGGTTTACACCCTGGACAACCTGAATAAGTTCACTCAGTAC GGCCTGGTGGTGCAGGCCTGTAACCGGGCCGGCACGGGGCCTTCTTCTCAGGAAATCATC ACCACCACTCTCGAGGATGTGCCCAGTTACCCCCCCGAAAATGTCCAAGCCATAGCAACA TCACCAGAAAGCATATCAATATCCTGGTCCACACTTTCCAAGGAAGCCTTGAATGGAATT CTCCAGGGGTTCAGAGTCATTTACTGGGCCAACCTCATGGACGGAGAGCTGGGTGAGATT AAAAACATCACCACCACACAGCCTTCACTGGAGCTGGACGGGCTGGAAAAGTACACCAAC TACAGCATCCAGGTGCTGGCCTTCACCCGCGCAGGAGACGGGGTCAGGAGTGAGCAGATC TTCACCCGGACCAAAGAGGATGTTCCAGGTCCTCCCGCGGGTGTGAAGGCAGCGGCGGCC TCAGCCTCCATGGTCTTTGTGTCCTGGCTTCCCCCTCTCAAGCTGAACGGCATCATCCGA AAGTACACTGTATTCTGCTCCCACCCCTATCCCACAGTGATCAGCGAGTTTGAGGCCTCT CCCGACTCGTTTTCCTACAGAATTCCCAACCTGAGTAGGAATCGTCAGTACAGCGTCTGG GTGGTGGCTGTTACTTCAGCCGGAAGAGGCAACAGCAGTGAAATCATCACAGTTGAGCCA CTAGCAAAAGCTCCTGCACGAATCCTGACCTTCAGTGGGACAGTGACTACTCCATGGATG AAAGACATTGTCTTGCCTTGTAAGGCTGTTGGGGACCCTTCTCCTGCAGTCAAATGGATG AAAGACAGTAACGGGACACCCAGTCTAGTAACGATTGATGGGCGGAGGAGCATCTTTAGC AACGGAAGCTTCATTATTCGCACGGTGAAAGCAGAAGACTCCGGCTATTACAGCTGCATT GCCAATAACAACTGGGGATCTGATGAAATTATTTTAAACTTACAAGTACAAGTTCCACCA GATCAGCCTCGGCTTACAGTCTCCAAGACCACGTCTTCCTCCATCACCCTTTCTTGGCTC CCTGGAGACAACGGGGGCAGCTCTATCAGAGGATACATACTGCAGTACTCCGAGGACAAT AGTGAGCAGTGGGGGAGTTTTCCAATCAGCCCCAGCGAACGTTCCTATCGCTTGGAAAAT CTCAAATGTGGGACTTGGTATAAGTTCACACTGACAGCCCAAAATGGAGTGGGCCCAGGG CGCATAAGTGAAATCATAGAAGCAAAGACCTTAGGAAAAGAGCCCCAGTTCTCAAAGGAG CAGGAGCTGTTTGCCAGCATCAACACCACACGCGTGAGGCTGAACCTCATTGGCTGGAAT GATGGCGGCTGCCCCATCACCTCCTTCACACTAGAGTACAGGCCCTTTGGGACCACAGTT TGGACCACAGCTCAGAGGACCTCTCTCTCCAAGTCCTACATCCTGTATGACCTGCAGGAA GCCACCTGGTATGAGCTGCAGATGCGGGTGTGCAACAGTGCGGGCTGCGCGGAGAAGCAG GCCAACTTCGCTACGCTGAACTACGATGGCAGTACAATTCCTCCACTCATTAAGTCAGTT GTCCAAAACGAAGAAGGGCTGACGACCAACGAGGGGCTCAAGATGCTGGTGACCATCTCC TGTATCCTGGTGGGGGTCTTGCTGCTGTTTGTGCTCCTGCTGGTTGTGCGGAGGAGGCGG CGGGAGCAGAGGCTAAAGAGGCTGCGAGATGCAAAGAGTTTAGCTGAAATGCTCATGAGT AAGAATACCCGGACTTCAGATACGTTAAGCAAGCAACAGCAGACCCTGCGAATGCACATC GACATACCCAGGGCTCAGCTTTTGATTGAAGAGAGAGACACGATGGAGACCATTGATGAT CGCTCCACGGTTCTGTTGACGGATGCTGACTTTGGAGAGGCAGCTAAGCAGAAGTCCCTG ACGGTCACTCACACGGTCCATTACCAATCGGTGTCTCAGGCCACTGGGCCCTTAGTGGAT GTTTCAGACGCTCGGCCGGGAACGAATCCCACCACCAGGAGGAATGCCAAGGCTGGGCCC ACAGCGAGAAACCGCTATGCCAGCCAGTGGACCCTCAACCGACCCCACCCCACCATCTCA GCACACACCCTCACCACAGACTGGAGGCTGCCAACACCCAGGGCTGCAGGATCAGTAGAC AAAGAGAGCGACAGTTACAGCGTCAGCCCCTCGCAAGACACAGATCGAGCAAGAAGCAGC ATGGTCTCCACAGAAAGTGCCTCCTCCACTTACGAAGAACTGGCCAGGGCCTACGAACAC GCCAAGATGGAAGAGCAACTGAGGCACGCCAAGTTCACCATCACGGAGTGCTTCATATCA GACACGTCATCGGAGCAGTTGACGGCAGGGACAAATGAGTACACGGACAGTCTGACCTCC AGCACCCCTTCCGAATCGGGAATCTGCAGGTTCACTGCATCTCCCCCCAAACCTCAGGAT GGAGGAAGAGTAATGAATATGGCAGTTCCAAAGGCACATCGGCCAGGTGACCTCATACAT TTGCCTCCATACCTTAGAATGGACTTTTTGTTAAACCGAGGTGGTCCAGGCACCAGCAGG GACCTGAGCTTAGGACAAGCATGCTTGGAACCTCAGAAAAGCCGGACCCTGAAGCGCCCC ACGGTCCTGGAGCCCATCCCGATGGAAGCCGCCTCCTCCGCCTCCTCCACGAGAGAAGGA CAGTCGTGGCAGCCGGGGGCCGTGGCCACATTACCTCAGCGGGAGGGAGCAGAGCTGGGA CAGGCAGCTAAAATGAGCAGCTCCCAAGAATCACTGCTCGACTCCCGGGGCCATTTGAAA GGAAACAATCCTTACGCAAAATCTTACACCCTGGTA
Cloned ORF protein sequence for pF1KB3816 Download>KIBB3816 2012 aa MWILALSLFQSFANVFSEDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYL ATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKA VLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGA LYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFEHRKAMAGQ RVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYG TAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNV RITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSP AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGG VYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKN SNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQ PFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLS LMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSM YLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTK EVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKART ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRM YAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGY QIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEII TTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEI KNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAA SASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVW VVAVTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWM KDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPP DQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLEN LKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWN DGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAEKQ ANFATLNYDGSTIPPLIKSVVQNEEGLTTNEGLKMLVTISCILVGVLLLFVLLLVVRRRR REQRLKRLRDAKSLAEMLMSKNTRTSDTLSKQQQTLRMHIDIPRAQLLIEERDTMETIDD RSTVLLTDADFGEAAKQKSLTVTHTVHYQSVSQATGPLVDVSDARPGTNPTTRRNAKAGP TARNRYASQWTLNRPHPTISAHTLTTDWRLPTPRAAGSVDKESDSYSVSPSQDTDRARSS MVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDTSSEQLTAGTNEYTDSLTS STPSESGICRFTASPPKPQDGGRVMNMAVPKAHRPGDLIHLPPYLRMDFLLNRGGPGTSR DLSLGQACLEPQKSRTLKRPTVLEPIPMEAASSASSTREGQSWQPGAVATLPQREGAELG QAAKMSSSQESLLDSRGHLKGNNPYAKSYTLV
Nucleotide Sequence (with vector) for pF1KB3816 Download>pF1KB3816 9149 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGTGGATACTG GCTCTCTCCTTGTTCCAGAGCTTCGCGAATGTTTTCAGTGAAGACCTACACTCCAGCCTC TACTTTGTCAATGCATCTCTGCAAGAGGTAGTGTTTGCCAGCACCACGGGGACTCTGGTG CCCTGCCCCGCAGCAGGCATCCCTCCTGTGACTCTCAGATGGTACCTAGCCACGGGCGAG GAGATCTACGATGTCCCCGGGATCCGCCACGTCCACCCCAACGGCACTCTCCAAATTTTC CCCTTCCCTCCTTCAAGCTTCAGTACCTTAATCCATGATAATACTTATTATTGCACAGCT GAAAATCCTTCAGGGAAAATTAGAAGTCAGGATGTCCACATCAAGGCTGTTTTACGGGAG CCCTATACAGTCCGTGTGGAGGACCAGAAAACCATGAGAGGCAATGTTGCGGTCTTCAAG TGCATTATCCCCTCCTCGGTGGAGGCGTACATCACTGTCGTCTCATGGGAGAAAGACACT GTTTCACTTGTCTCAGGATCTAGATTTCTCATCACATCCACGGGAGCCTTGTATATTAAA GATGTACAGAATGAAGATGGATTGTATAACTACCGCTGCATCACGCGGCATCGATACACC GGAGAGACGAGGCAGAGCAACAGCGCCAGACTTTTTGTATCAGACCCAGCGAACTCAGCC CCATCCATACTGGATGGGTTTGAGCATCGCAAAGCCATGGCTGGGCAGCGTGTGGAGCTG CCTTGCAAAGCGCTCGGGCACCCTGAGCCAGATTACCGCTGGCTGAAGGACAACATGCCC CTGGAACTTTCAGGGAGGTTCCAGAAGACCGTGACGGGGCTGCTCATTGAGAACATTCGC CCCTCGGACTCAGGCAGCTATGTTTGTGAAGTGTCCAACAGATACGGAACTGCTAAGGTG ATAGGCCGCCTGTACGTGAAACAGCCACTGAAAGCCACCATCAGTCCCAGGAAGGTTAAA AGCAGCGTGGGTAGCCAAGTTTCCTTGTCCTGCAGCGTGACAGGAACTGAGGACCAGGAA CTCTCCTGGTACCGCAATGGTGAAATCCTCAACCCTGGAAAAAATGTGAGGATCACAGGG ATCAACCACGAAAACCTTATAATGGATCACATGGTCAAAAGTGACGGGGGCGCATACCAG TGCTTTGTGCGCAAGGACAAGCTGTCCGCTCAAGACTATGTGCAGGTGGTCCTTGAAGAT GGAACTCCCAAAATTATTTCTGCCTTTAGTGAAAAGGTGGTGAGTCCAGCAGAGCCGGTT TCCCTTATGTGCAACGTGAAGGGAACACCTTTGCCCACGATCACGTGGACCCTGGACGAT GACCCGATTCTCAAGGGTGGCAGTCACCGCATCAGCCAGATGATCACGTCGGAGGGGAAC GTGGTCAGCTACCTGAACATCTCCAGCTCCCAGGTCCGGGACGGGGGAGTCTACCGCTGC ACTGCCAACAACTCGGCGGGAGTCGTCCTGTACCAGGCTCGAATAAACGTAAGAGGGCCT GCAAGCATTCGACCAATGAAAAACATCACAGCAATAGCAGGACGGGACACATACATTCAC TGTCGTGTGATTGGCTATCCGTATTACTCCATTAAATGGTACAAGAACTCTAACCTGCTT CCTTTCAACCACCGCCAAGTGGCATTTGAGAACAATGGAACTCTTAAACTTTCAGATGTG CAAAAGGAAGTGGACGAGGGGGAGTACACGTGCAACGTGTTGGTTCAACCACAACTCTCC ACCAGCCAGAGCGTCCACGTGACCGTGAAAGTTCCGCCTTTCATACAACCCTTTGAGTTT CCAAGATTCTCCATTGGGCAGCGGGTCTTCATCCCCTGTGTTGTGGTCTCAGGGGACTTA CCCATCACGATCACCTGGCAGAAGGATGGCCGGCCAATCCCTGGGAGCCTTGGGGTGACC ATTGACAATATTGACTTCACGAGCTCCTTGAGGATTTCCAATCTCTCGCTCATGCACAAT GGGAATTACACCTGCATAGCCCGGAATGAGGCCGCCGCTGTGGAGCACCAAAGCCAGTTG ATTGTCAGAGTTCCTCCCAAGTTTGTGGTTCAGCCACGGGACCAGGACGGGATTTATGGC AAAGCAGTCATCCTCAATTGTTCTGCTGAGGGTTACCCTGTACCTACCATCGTGTGGAAA TTCTCTAAAGGTGCTGGGGTTCCCCAGTTCCAGCCAATTGCCCTAAATGGCCGAATCCAA GTTCTCAGCAATGGGTCGTTGCTGATCAAGCATGTCGTGGAGGAAGACAGTGGCTACTAC CTCTGCAAGGTCAGCAACGATGTGGGCGCAGACGTCAGCAAGTCCATGTACCTCACGGTT AAAATTCCTGCGATGATAACATCCTATCCAAATACTACCCTGGCCACGCAGGGGCAGAAA AAGGAGATGAGCTGCACGGCGCATGGTGAGAAGCCCATTATAGTCCGCTGGGAGAAGGAG GACCGAATCATTAACCCTGAGATGGCCCGTTATCTTGTGTCCACCAAGGAGGTGGGAGAA GAGGTGATTTCTACTCTGCAGATTTTGCCAACTGTGAGAGAAGATTCTGGTTTCTTTTCC TGCCATGCTATTAATTCTTATGGGGAGGACCGTGGAATAATTCAGCTCACAGTGCAAGAG CCCCCAGACCCTCCCGAAATTGAGATCAAAGATGTCAAAGCACGCACAATTACGCTCAGG TGGACCATGGGGTTTGATGGAAACAGTCCCATCACAGGCTACGATATTGAATGCAAAAAT AAATCAGACTCCTGGGATTCTGCTCAGAGAACCAAAGATGTTTCCCCTCAGCTGAACTCG GCCACCATCATTGATATCCACCCTTCCTCCACCTACAGCATCCGCATGTACGCCAAGAAC CGGATTGGCAAGAGCGAGCCCAGCAACGAGCTCACCATCACGGCGGACGAGGCAGCTCCT GATGGTCCACCTCAGGAAGTTCACCTGGAGCCTATATCATCTCAGAGCATCAGGGTCACA TGGAAGGCTCCCAAGAAACATTTGCAAAATGGGATTATCCGTGGCTACCAAATAGGTTAC CGAGAGTACAGCACTGGGGGTAACTTCCAATTCAACATTATCAGTGTCGACACCAGCGGG GACAGTGAGGTTTACACCCTGGACAACCTGAATAAGTTCACTCAGTACGGCCTGGTGGTG CAGGCCTGTAACCGGGCCGGCACGGGGCCTTCTTCTCAGGAAATCATCACCACCACTCTC GAGGATGTGCCCAGTTACCCCCCCGAAAATGTCCAAGCCATAGCAACATCACCAGAAAGC ATATCAATATCCTGGTCCACACTTTCCAAGGAAGCCTTGAATGGAATTCTCCAGGGGTTC AGAGTCATTTACTGGGCCAACCTCATGGACGGAGAGCTGGGTGAGATTAAAAACATCACC ACCACACAGCCTTCACTGGAGCTGGACGGGCTGGAAAAGTACACCAACTACAGCATCCAG GTGCTGGCCTTCACCCGCGCAGGAGACGGGGTCAGGAGTGAGCAGATCTTCACCCGGACC AAAGAGGATGTTCCAGGTCCTCCCGCGGGTGTGAAGGCAGCGGCGGCCTCAGCCTCCATG GTCTTTGTGTCCTGGCTTCCCCCTCTCAAGCTGAACGGCATCATCCGAAAGTACACTGTA TTCTGCTCCCACCCCTATCCCACAGTGATCAGCGAGTTTGAGGCCTCTCCCGACTCGTTT TCCTACAGAATTCCCAACCTGAGTAGGAATCGTCAGTACAGCGTCTGGGTGGTGGCTGTT ACTTCAGCCGGAAGAGGCAACAGCAGTGAAATCATCACAGTTGAGCCACTAGCAAAAGCT CCTGCACGAATCCTGACCTTCAGTGGGACAGTGACTACTCCATGGATGAAAGACATTGTC TTGCCTTGTAAGGCTGTTGGGGACCCTTCTCCTGCAGTCAAATGGATGAAAGACAGTAAC GGGACACCCAGTCTAGTAACGATTGATGGGCGGAGGAGCATCTTTAGCAACGGAAGCTTC ATTATTCGCACGGTGAAAGCAGAAGACTCCGGCTATTACAGCTGCATTGCCAATAACAAC TGGGGATCTGATGAAATTATTTTAAACTTACAAGTACAAGTTCCACCAGATCAGCCTCGG CTTACAGTCTCCAAGACCACGTCTTCCTCCATCACCCTTTCTTGGCTCCCTGGAGACAAC GGGGGCAGCTCTATCAGAGGATACATACTGCAGTACTCCGAGGACAATAGTGAGCAGTGG GGGAGTTTTCCAATCAGCCCCAGCGAACGTTCCTATCGCTTGGAAAATCTCAAATGTGGG ACTTGGTATAAGTTCACACTGACAGCCCAAAATGGAGTGGGCCCAGGGCGCATAAGTGAA ATCATAGAAGCAAAGACCTTAGGAAAAGAGCCCCAGTTCTCAAAGGAGCAGGAGCTGTTT GCCAGCATCAACACCACACGCGTGAGGCTGAACCTCATTGGCTGGAATGATGGCGGCTGC CCCATCACCTCCTTCACACTAGAGTACAGGCCCTTTGGGACCACAGTTTGGACCACAGCT CAGAGGACCTCTCTCTCCAAGTCCTACATCCTGTATGACCTGCAGGAAGCCACCTGGTAT GAGCTGCAGATGCGGGTGTGCAACAGTGCGGGCTGCGCGGAGAAGCAGGCCAACTTCGCT ACGCTGAACTACGATGGCAGTACAATTCCTCCACTCATTAAGTCAGTTGTCCAAAACGAA GAAGGGCTGACGACCAACGAGGGGCTCAAGATGCTGGTGACCATCTCCTGTATCCTGGTG GGGGTCTTGCTGCTGTTTGTGCTCCTGCTGGTTGTGCGGAGGAGGCGGCGGGAGCAGAGG CTAAAGAGGCTGCGAGATGCAAAGAGTTTAGCTGAAATGCTCATGAGTAAGAATACCCGG ACTTCAGATACGTTAAGCAAGCAACAGCAGACCCTGCGAATGCACATCGACATACCCAGG GCTCAGCTTTTGATTGAAGAGAGAGACACGATGGAGACCATTGATGATCGCTCCACGGTT CTGTTGACGGATGCTGACTTTGGAGAGGCAGCTAAGCAGAAGTCCCTGACGGTCACTCAC ACGGTCCATTACCAATCGGTGTCTCAGGCCACTGGGCCCTTAGTGGATGTTTCAGACGCT CGGCCGGGAACGAATCCCACCACCAGGAGGAATGCCAAGGCTGGGCCCACAGCGAGAAAC CGCTATGCCAGCCAGTGGACCCTCAACCGACCCCACCCCACCATCTCAGCACACACCCTC ACCACAGACTGGAGGCTGCCAACACCCAGGGCTGCAGGATCAGTAGACAAAGAGAGCGAC AGTTACAGCGTCAGCCCCTCGCAAGACACAGATCGAGCAAGAAGCAGCATGGTCTCCACA GAAAGTGCCTCCTCCACTTACGAAGAACTGGCCAGGGCCTACGAACACGCCAAGATGGAA GAGCAACTGAGGCACGCCAAGTTCACCATCACGGAGTGCTTCATATCAGACACGTCATCG GAGCAGTTGACGGCAGGGACAAATGAGTACACGGACAGTCTGACCTCCAGCACCCCTTCC GAATCGGGAATCTGCAGGTTCACTGCATCTCCCCCCAAACCTCAGGATGGAGGAAGAGTA ATGAATATGGCAGTTCCAAAGGCACATCGGCCAGGTGACCTCATACATTTGCCTCCATAC CTTAGAATGGACTTTTTGTTAAACCGAGGTGGTCCAGGCACCAGCAGGGACCTGAGCTTA GGACAAGCATGCTTGGAACCTCAGAAAAGCCGGACCCTGAAGCGCCCCACGGTCCTGGAG CCCATCCCGATGGAAGCCGCCTCCTCCGCCTCCTCCACGAGAGAAGGACAGTCGTGGCAG CCGGGGGCCGTGGCCACATTACCTCAGCGGGAGGGAGCAGAGCTGGGACAGGCAGCTAAA ATGAGCAGCTCCCAAGAATCACTGCTCGACTCCCGGGGCCATTTGAAAGGAAACAATCCT TACGCAAAATCTTACACCCTGGTAGTTTAAACGAATTCGAGCTCGGTACCCGGGGATCCT CTAGAGTCGACCTGCAGGCATGCAAGCTGATCCGGCTGCTAACAAAGCCCGAAAGGAAGC TGAGTTGGCTGCTGCCACCGCTGAGCAATAACTAGCATAACCCCTTGGGGCCTCTAAACG GGTCTTGAGGGGTTTTTTGCTGAAAGGAGGAACTATATCCGGTTCGCTTGCTGTCCATAA AACCGCCCAGTCTAGCTATCGCCATGTAAGCCCACTGCAAGCTACCTGCTTTCTCTTTGC GCTTGCGTTTTCCCTTGTCCAGATAGCCCAGTAGCTGACATTCATCCGGGGTCAGCACCG TTTCTGCGGACTGGCTTTCTACGTGTTCCGCTTCCTTTAGCAGCCCTTGCGCCCTGAGTG CTTGCGGCAGCGTGAGCTTCAAAAGAATTGCCAGCTGGGGCGCCCTCTGGTAAGGTTGGG AAGCCCTGCAAAGTAAACTGGATGGCTTTCTTGCCGCCAAGGATCTGATGGCGCAGGGGA TCAAGATCTGATCAAGAGACAGGATGACGGTCGTTTCGCATGCTTGAACAAGATGGATTG CACGCAGGTTCTCCGGCCGCTTGGGTGGAGAGGCTATTCGGCTATGACTGGGCACAACAG ACAATCGGCTGCTCTGATGCCGCCGTGTTCCGGCTGTCAGCGCAGGGGCGCCCGGTTCTT TTTGTCAAGACCGACCTGTCCGGTGCCCTGAATGAACTGCAGGACGAGGCAGCGCGGCTA TCGTGGCTGGCCACGACGGGCGTTCCTTGCGCAGCTGTGCTCGACGTTGTCACTGAAGCG GGAAGGGACTGGCTGCTATTGGGCGAAGTGCCGGGGCAGGATCTCCTGTCATCTCACCTT GCTCCTGCCGAGAAAGTATCCATCATGGCTGATGCAATGCGGCGGCTGCATACGCTTGAT CCGGCTACCTGCCCATTCGACCACCAAGCGAAACATCGCATCGAGCGAGCACGCACTCGG ATGGAAGCCGGTCTTGTCGATCAGGATGATCTGGACGAAGAGCATCAGGGGCTCGCGCCA GCCGAACTGTTCGCCAGGCTCAAGGCGCGTATGCCGGATGGTGAGGATCTCGTCGTGACT CATGGCGATGCCTGCTTGCCGAATATCATGGTGGAAAATGGCCGCTTTTCTGGATTCATC GACTGTGGCCGGCTGGGTGTGGCGGACCGCTATCAGGACATAGCGTTGGCTACCCGTGAT ATTGCTGAAGAGCTTGGCGGCGAATGGGCTGACCGCTTCCTCGTGCTTTACGGTATCGCC GCTCCCGATTCGCAGCGCATCGCCTTCTATCGCCTTCTTGACGAGTTCTTCTGAGCGGGA CTCTGGGGTTCGAAATGACCGACCAAGCGACGCCCAACCGGTATCAGCTCACTCAAAGGC GGTAATACGGTTATCCACAGAATCAGGGGATAACGCAGGAAAGAACATGTGAGCAAAAGG CCAGCAAAAGGCCAGGAACCGTAAAAAGGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCG CCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCAGAGGTGGCGAAACCCGACAGG ACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGAC CCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCA TAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGT GCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTC CAACCCGGTAAGACACGACTTATCGCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAG AGCGAGGTATGTAGGCGGTGCTACAGAGTTCTTGAAGTGGTGGCCTAACTACGGCTACAC TAGAAGGACAGTATTTGGTATCTGCGCTCTGCTGAAGCCAGTTACCTTCGGAAAAAGAGT TGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAA GCAGCAGATTACGCGCAGAAAAAAAGGATTTCAAGAAGATCCTTTGATCTTTTCTACGGG GTCTGACGCTCAGTGGAACGAAAACTCACGTTAAGGGATTTTGGTCATGAGATTATCAAA AAGGATCTTCACCTAGATCCTTTTATAGTCCGGAAATACAGGAACGCACGCTGGATGGCC CTTCGCTGGGATGGTGAAACCATGAAAAATGGCAGCTTCAGTGGATTAAGTGGGGGTAAT GTGGCCTGTACCCTCTGGTTGCATAGGTATTCATACGGTTAAAATTTATCAGGCGCGATT GCGGCAGTTTTTCGGGTGGTTTGTTGCCATTTTTACCTGTCTGCTGCCGTGATCGCGCTG AACGCGTTTTAGCGGTGCGTACAATTAAGGGATTATGGTAAATCCACTTACTGTCTGCCC TCGTAGCCATCGAGATAAACCGCAGTACTCCGGCCACGATGCGTCCGGCGTAGAGGATCG AGATCTTTTCAGCCTGATACAGATTAAATCAGAACGCAGAAGCGGTCTGATAAAACAGAA TTTGCCTGGCGGCAGTAGCGCGGTGGTCCCACCTGACCCCATGCCGAACTCAGAAGTGAA ACGCCGTAGCGCCGATGGTAGTGTGGGGTCTCCCCATGCGAGAGTAGGGAACTGCCAGGC ATCAAATAAAACGAAAGGCTCAGTCGAAAGACTGGGCCTTTCGTTTTATCTGTTGTTTGT CGGTGAACGCTCTCCTGAGTAGGACAAATCCGCCGGGAGCGGATTTGAACGTTGCGAAGC AACGGCCCGGAGGGTGGCGGGCAGGACGCCCGCCATAAACTGCCAGGCATCAAATTAAGC AGAAGGCCATCCTGACGGATGGCCTTTTTGCGTTTCTACAAACTCTTTTGTTTATTTTTC TAAATACATTCAAATATGTATCCGCTCAT
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