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SpecieshumanProduct IDFHC00331Cloning SiteSgfI-PmeIGeneKIBB3816SymbolDSCAM
Alias : CHD2, CHD2-42, CHD2-52DescriptionDown syndrome cell adhesion molecule, transcript variant 1Original Clone IDfg03766
Characterization of the cloned ORF
N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand
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Length: 6036 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 2012 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS42929.1 0 100.0 DSCAM CCDS8384.1 0 60.9 DSCAML1 CCDS33790.1 1.4e-24 25.2 CNTN3 CCDS55153.1 6.3e-23 25.1 NRCAM CCDS54424.1 3e-21 23.3 TTN
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR013098 231 304 PF07679 Immunoglobulin I-set IPR013098 316 389 PF07679 Immunoglobulin I-set IPR013098 407 501 PF07679 Immunoglobulin I-set IPR013098 508 593 PF07679 Immunoglobulin I-set IPR013098 599 686 PF07679 Immunoglobulin I-set IPR013098 690 783 PF07679 Immunoglobulin I-set IPR013098 790 882 PF07679 Immunoglobulin I-set IPR003961 888 972 PF00041 Fibronectin IPR003961 987 1076 PF00041 Fibronectin IPR003961 1091 1177 PF00041 Fibronectin IPR003961 1191 1273 PF00041 Fibronectin IPR013098 1301 1376 PF07679 Immunoglobulin I-set IPR003961 1384 1462 PF00041 Fibronectin IPR003961 1485 1556 PF00041 Fibronectin HMMSmart IPR003598 37 109 SM00408 Immunoglobulin subtype 2 IPR003599 130 218 SM00409 Immunoglobulin subtype IPR003599 231 311 SM00409 Immunoglobulin subtype IPR003598 237 300 SM00408 Immunoglobulin subtype 2 IPR003596 241 295 SM00406 Immunoglobulin V-set IPR003599 320 403 SM00409 Immunoglobulin subtype IPR003598 326 392 SM00408 Immunoglobulin subtype 2 IPR003599 413 502 SM00409 Immunoglobulin subtype IPR003598 419 491 SM00408 Immunoglobulin subtype 2 IPR003599 510 594 SM00409 Immunoglobulin subtype IPR003598 516 582 SM00408 Immunoglobulin subtype 2 IPR003599 602 687 SM00409 Immunoglobulin subtype IPR003598 608 676 SM00408 Immunoglobulin subtype 2 IPR003599 696 785 SM00409 Immunoglobulin subtype IPR003598 702 773 SM00408 Immunoglobulin subtype 2 IPR003596 706 768 SM00406 Immunoglobulin V-set IPR003599 794 883 SM00409 Immunoglobulin subtype IPR003598 800 872 SM00408 Immunoglobulin subtype 2 IPR003961 885 969 SM00060 Fibronectin IPR003961 985 1073 SM00060 Fibronectin IPR003961 1088 1174 SM00060 Fibronectin IPR003961 1189 1270 SM00060 Fibronectin IPR003599 1292 1377 SM00409 Immunoglobulin subtype IPR003598 1301 1366 SM00408 Immunoglobulin subtype 2 IPR003596 1302 1361 SM00406 Immunoglobulin V-set IPR003961 1380 1460 SM00060 Fibronectin IPR003961 1477 1557 SM00060 Fibronectin ProfileScan IPR007110 125 216 PS50835 Immunoglobulin-like IPR007110 225 305 PS50835 Immunoglobulin-like IPR007110 313 401 PS50835 Immunoglobulin-like IPR007110 407 500 PS50835 Immunoglobulin-like IPR007110 504 592 PS50835 Immunoglobulin-like IPR007110 596 685 PS50835 Immunoglobulin-like IPR007110 690 783 PS50835 Immunoglobulin-like IPR007110 787 883 PS50835 Immunoglobulin-like IPR003961 885 978 PS50853 Fibronectin IPR003961 984 1082 PS50853 Fibronectin IPR003961 1088 1183 PS50853 Fibronectin IPR003961 1189 1279 PS50853 Fibronectin IPR007110 1285 1377 PS50835 Immunoglobulin-like IPR003961 1376 1470 PS50853 Fibronectin IPR003961 1476 1566 PS50853 Fibronectin
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 1594 KMLVTISCILVGVLLLFVLLLVV 1616 PRIMARY 23
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_001380 2012 602523 100.0 100.0 NP_001258463 1994 602523 99.1 100.0 XP_016883770 1776 602523 100.0 88.3 NP_065744 2113 611782 60.9 98.1 XP_011541220 1977 611782 60.5 93.6 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pFN21AB3816 Download>KIBB3816 6036 bp ATGTGGATACTGGCTCTCTCCTTGTTCCAGAGCTTCGCGAATGTTTTCAGTGAAGACCTA CACTCCAGCCTCTACTTTGTCAATGCATCTCTGCAAGAGGTAGTGTTTGCCAGCACCACG GGGACTCTGGTGCCCTGCCCCGCAGCAGGCATCCCTCCTGTGACTCTCAGATGGTACCTA GCCACGGGCGAGGAGATCTACGATGTCCCCGGGATCCGCCACGTCCACCCCAACGGCACT CTCCAAATTTTCCCCTTCCCTCCTTCAAGCTTCAGTACCTTAATCCATGATAATACTTAT TATTGCACAGCTGAAAATCCTTCAGGGAAAATTAGAAGTCAGGATGTCCACATCAAGGCT GTTTTACGGGAGCCCTATACAGTCCGTGTGGAGGACCAGAAAACCATGAGAGGCAATGTT GCGGTCTTCAAGTGCATTATCCCCTCCTCGGTGGAGGCGTACATCACTGTCGTCTCATGG GAGAAAGACACTGTTTCACTTGTCTCAGGATCTAGATTTCTCATCACATCCACGGGAGCC TTGTATATTAAAGATGTACAGAATGAAGATGGATTGTATAACTACCGCTGCATCACGCGG CATCGATACACCGGAGAGACGAGGCAGAGCAACAGCGCCAGACTTTTTGTATCAGACCCA GCGAACTCAGCCCCATCCATACTGGATGGGTTTGAGCATCGCAAAGCCATGGCTGGGCAG CGTGTGGAGCTGCCTTGCAAAGCGCTCGGGCACCCTGAGCCAGATTACCGCTGGCTGAAG GACAACATGCCCCTGGAACTTTCAGGGAGGTTCCAGAAGACCGTGACGGGGCTGCTCATT GAGAACATTCGCCCCTCGGACTCAGGCAGCTATGTTTGTGAAGTGTCCAACAGATACGGA ACTGCTAAGGTGATAGGCCGCCTGTACGTGAAACAGCCACTGAAAGCCACCATCAGTCCC AGGAAGGTTAAAAGCAGCGTGGGTAGCCAAGTTTCCTTGTCCTGCAGCGTGACAGGAACT GAGGACCAGGAACTCTCCTGGTACCGCAATGGTGAAATCCTCAACCCTGGAAAAAATGTG AGGATCACAGGGATCAACCACGAAAACCTTATAATGGATCACATGGTCAAAAGTGACGGG GGCGCATACCAGTGCTTTGTGCGCAAGGACAAGCTGTCCGCTCAAGACTATGTGCAGGTG GTCCTTGAAGATGGAACTCCCAAAATTATTTCTGCCTTTAGTGAAAAGGTGGTGAGTCCA GCAGAGCCGGTTTCCCTTATGTGCAACGTGAAGGGAACACCTTTGCCCACGATCACGTGG ACCCTGGACGATGACCCGATTCTCAAGGGTGGCAGTCACCGCATCAGCCAGATGATCACG TCGGAGGGGAACGTGGTCAGCTACCTGAACATCTCCAGCTCCCAGGTCCGGGACGGGGGA GTCTACCGCTGCACTGCCAACAACTCGGCGGGAGTCGTCCTGTACCAGGCTCGAATAAAC GTAAGAGGGCCTGCAAGCATTCGACCAATGAAAAACATCACAGCAATAGCAGGACGGGAC ACATACATTCACTGTCGTGTGATTGGCTATCCGTATTACTCCATTAAATGGTACAAGAAC TCTAACCTGCTTCCTTTCAACCACCGCCAAGTGGCATTTGAGAACAATGGAACTCTTAAA CTTTCAGATGTGCAAAAGGAAGTGGACGAGGGGGAGTACACGTGCAACGTGTTGGTTCAA CCACAACTCTCCACCAGCCAGAGCGTCCACGTGACCGTGAAAGTTCCGCCTTTCATACAA CCCTTTGAGTTTCCAAGATTCTCCATTGGGCAGCGGGTCTTCATCCCCTGTGTTGTGGTC TCAGGGGACTTACCCATCACGATCACCTGGCAGAAGGATGGCCGGCCAATCCCTGGGAGC CTTGGGGTGACCATTGACAATATTGACTTCACGAGCTCCTTGAGGATTTCCAATCTCTCG CTCATGCACAATGGGAATTACACCTGCATAGCCCGGAATGAGGCCGCCGCTGTGGAGCAC CAAAGCCAGTTGATTGTCAGAGTTCCTCCCAAGTTTGTGGTTCAGCCACGGGACCAGGAC GGGATTTATGGCAAAGCAGTCATCCTCAATTGTTCTGCTGAGGGTTACCCTGTACCTACC ATCGTGTGGAAATTCTCTAAAGGTGCTGGGGTTCCCCAGTTCCAGCCAATTGCCCTAAAT GGCCGAATCCAAGTTCTCAGCAATGGGTCGTTGCTGATCAAGCATGTCGTGGAGGAAGAC AGTGGCTACTACCTCTGCAAGGTCAGCAACGATGTGGGCGCAGACGTCAGCAAGTCCATG TACCTCACGGTTAAAATTCCTGCGATGATAACATCCTATCCAAATACTACCCTGGCCACG CAGGGGCAGAAAAAGGAGATGAGCTGCACGGCGCATGGTGAGAAGCCCATTATAGTCCGC TGGGAGAAGGAGGACCGAATCATTAACCCTGAGATGGCCCGTTATCTTGTGTCCACCAAG GAGGTGGGAGAAGAGGTGATTTCTACTCTGCAGATTTTGCCAACTGTGAGAGAAGATTCT GGTTTCTTTTCCTGCCATGCTATTAATTCTTATGGGGAGGACCGTGGAATAATTCAGCTC ACAGTGCAAGAGCCCCCAGACCCTCCCGAAATTGAGATCAAAGATGTCAAAGCACGCACA ATTACGCTCAGGTGGACCATGGGGTTTGATGGAAACAGTCCCATCACAGGCTACGATATT GAATGCAAAAATAAATCAGACTCCTGGGATTCTGCTCAGAGAACCAAAGATGTTTCCCCT CAGCTGAACTCGGCCACCATCATTGATATCCACCCTTCCTCCACCTACAGCATCCGCATG TACGCCAAGAACCGGATTGGCAAGAGCGAGCCCAGCAACGAGCTCACCATCACGGCGGAC GAGGCAGCTCCTGATGGTCCACCTCAGGAAGTTCACCTGGAGCCTATATCATCTCAGAGC ATCAGGGTCACATGGAAGGCTCCCAAGAAACATTTGCAAAATGGGATTATCCGTGGCTAC CAAATAGGTTACCGAGAGTACAGCACTGGGGGTAACTTCCAATTCAACATTATCAGTGTC GACACCAGCGGGGACAGTGAGGTTTACACCCTGGACAACCTGAATAAGTTCACTCAGTAC GGCCTGGTGGTGCAGGCCTGTAACCGGGCCGGCACGGGGCCTTCTTCTCAGGAAATCATC ACCACCACTCTCGAGGATGTGCCCAGTTACCCCCCCGAAAATGTCCAAGCCATAGCAACA TCACCAGAAAGCATATCAATATCCTGGTCCACACTTTCCAAGGAAGCCTTGAATGGAATT CTCCAGGGGTTCAGAGTCATTTACTGGGCCAACCTCATGGACGGAGAGCTGGGTGAGATT AAAAACATCACCACCACACAGCCTTCACTGGAGCTGGACGGGCTGGAAAAGTACACCAAC TACAGCATCCAGGTGCTGGCCTTCACCCGCGCAGGAGACGGGGTCAGGAGTGAGCAGATC TTCACCCGGACCAAAGAGGATGTTCCAGGTCCTCCCGCGGGTGTGAAGGCAGCGGCGGCC TCAGCCTCCATGGTCTTTGTGTCCTGGCTTCCCCCTCTCAAGCTGAACGGCATCATCCGA AAGTACACTGTATTCTGCTCCCACCCCTATCCCACAGTGATCAGCGAGTTTGAGGCCTCT CCCGACTCGTTTTCCTACAGAATTCCCAACCTGAGTAGGAATCGTCAGTACAGCGTCTGG GTGGTGGCTGTTACTTCAGCCGGAAGAGGCAACAGCAGTGAAATCATCACAGTTGAGCCA CTAGCAAAAGCTCCTGCACGAATCCTGACCTTCAGTGGGACAGTGACTACTCCATGGATG AAAGACATTGTCTTGCCTTGTAAGGCTGTTGGGGACCCTTCTCCTGCAGTCAAATGGATG AAAGACAGTAACGGGACACCCAGTCTAGTAACGATTGATGGGCGGAGGAGCATCTTTAGC AACGGAAGCTTCATTATTCGCACGGTGAAAGCAGAAGACTCCGGCTATTACAGCTGCATT GCCAATAACAACTGGGGATCTGATGAAATTATTTTAAACTTACAAGTACAAGTTCCACCA GATCAGCCTCGGCTTACAGTCTCCAAGACCACGTCTTCCTCCATCACCCTTTCTTGGCTC CCTGGAGACAACGGGGGCAGCTCTATCAGAGGATACATACTGCAGTACTCCGAGGACAAT AGTGAGCAGTGGGGGAGTTTTCCAATCAGCCCCAGCGAACGTTCCTATCGCTTGGAAAAT CTCAAATGTGGGACTTGGTATAAGTTCACACTGACAGCCCAAAATGGAGTGGGCCCAGGG CGCATAAGTGAAATCATAGAAGCAAAGACCTTAGGAAAAGAGCCCCAGTTCTCAAAGGAG CAGGAGCTGTTTGCCAGCATCAACACCACACGCGTGAGGCTGAACCTCATTGGCTGGAAT GATGGCGGCTGCCCCATCACCTCCTTCACACTAGAGTACAGGCCCTTTGGGACCACAGTT TGGACCACAGCTCAGAGGACCTCTCTCTCCAAGTCCTACATCCTGTATGACCTGCAGGAA GCCACCTGGTATGAGCTGCAGATGCGGGTGTGCAACAGTGCGGGCTGCGCGGAGAAGCAG GCCAACTTCGCTACGCTGAACTACGATGGCAGTACAATTCCTCCACTCATTAAGTCAGTT GTCCAAAACGAAGAAGGGCTGACGACCAACGAGGGGCTCAAGATGCTGGTGACCATCTCC TGTATCCTGGTGGGGGTCTTGCTGCTGTTTGTGCTCCTGCTGGTTGTGCGGAGGAGGCGG CGGGAGCAGAGGCTAAAGAGGCTGCGAGATGCAAAGAGTTTAGCTGAAATGCTCATGAGT AAGAATACCCGGACTTCAGATACGTTAAGCAAGCAACAGCAGACCCTGCGAATGCACATC GACATACCCAGGGCTCAGCTTTTGATTGAAGAGAGAGACACGATGGAGACCATTGATGAT CGCTCCACGGTTCTGTTGACGGATGCTGACTTTGGAGAGGCAGCTAAGCAGAAGTCCCTG ACGGTCACTCACACGGTCCATTACCAATCGGTGTCTCAGGCCACTGGGCCCTTAGTGGAT GTTTCAGACGCTCGGCCGGGAACGAATCCCACCACCAGGAGGAATGCCAAGGCTGGGCCC ACAGCGAGAAACCGCTATGCCAGCCAGTGGACCCTCAACCGACCCCACCCCACCATCTCA GCACACACCCTCACCACAGACTGGAGGCTGCCAACACCCAGGGCTGCAGGATCAGTAGAC AAAGAGAGCGACAGTTACAGCGTCAGCCCCTCGCAAGACACAGATCGAGCAAGAAGCAGC ATGGTCTCCACAGAAAGTGCCTCCTCCACTTACGAAGAACTGGCCAGGGCCTACGAACAC GCCAAGATGGAAGAGCAACTGAGGCACGCCAAGTTCACCATCACGGAGTGCTTCATATCA GACACGTCATCGGAGCAGTTGACGGCAGGGACAAATGAGTACACGGACAGTCTGACCTCC AGCACCCCTTCCGAATCGGGAATCTGCAGGTTCACTGCATCTCCCCCCAAACCTCAGGAT GGAGGAAGAGTAATGAATATGGCAGTTCCAAAGGCACATCGGCCAGGTGACCTCATACAT TTGCCTCCATACCTTAGAATGGACTTTTTGTTAAACCGAGGTGGTCCAGGCACCAGCAGG GACCTGAGCTTAGGACAAGCATGCTTGGAACCTCAGAAAAGCCGGACCCTGAAGCGCCCC ACGGTCCTGGAGCCCATCCCGATGGAAGCCGCCTCCTCCGCCTCCTCCACGAGAGAAGGA CAGTCGTGGCAGCCGGGGGCCGTGGCCACATTACCTCAGCGGGAGGGAGCAGAGCTGGGA CAGGCAGCTAAAATGAGCAGCTCCCAAGAATCACTGCTCGACTCCCGGGGCCATTTGAAA GGAAACAATCCTTACGCAAAATCTTACACCCTGGTA
Cloned ORF protein sequence for pFN21AB3816 Download>KIBB3816 2012 aa MWILALSLFQSFANVFSEDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYL ATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKA VLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGA LYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFEHRKAMAGQ RVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYG TAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNV RITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSP AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGG VYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKN SNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQ PFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLS LMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPT IVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSM YLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTK EVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKART ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRM YAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGY QIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEII TTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEI KNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAA SASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVW VVAVTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWM KDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPP DQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLEN LKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWN DGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAEKQ ANFATLNYDGSTIPPLIKSVVQNEEGLTTNEGLKMLVTISCILVGVLLLFVLLLVVRRRR REQRLKRLRDAKSLAEMLMSKNTRTSDTLSKQQQTLRMHIDIPRAQLLIEERDTMETIDD RSTVLLTDADFGEAAKQKSLTVTHTVHYQSVSQATGPLVDVSDARPGTNPTTRRNAKAGP TARNRYASQWTLNRPHPTISAHTLTTDWRLPTPRAAGSVDKESDSYSVSPSQDTDRARSS MVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDTSSEQLTAGTNEYTDSLTS STPSESGICRFTASPPKPQDGGRVMNMAVPKAHRPGDLIHLPPYLRMDFLLNRGGPGTSR DLSLGQACLEPQKSRTLKRPTVLEPIPMEAASSASSTREGQSWQPGAVATLPQREGAELG QAAKMSSSQESLLDSRGHLKGNNPYAKSYTLV
Nucleotide Sequence (with vector) for pFN21AB3816 Download>pFN21AB3816 10741 bp TCAATATTGGCCATTAGCCATATTATTCATTGGTTATATAGCATAAATCAATATTGGCTA TTGGCCATTGCATACGTTGTATCTATATCATAATATGTACATTTATATTGGCTCATGTCC AATATGACCGCCATGTTGGCATTGATTATTGACTAGTTATTAATAGTAATCAATTACGGG GTCATTAGTTCATAGCCCATATATGGAGTTCCGCGTTACATAACTTACGGTAAATGGCCC GCCTGGCTGACCGCCCAACGACCCCCGCCCATTGACGTCAATAATGACGTATGTTCCCAT AGTAACGCCAATAGGGACTTTCCATTGACGTCAATGGGTGGAGTATTTACGGTAAACTGC CCACTTGGCAGTACATCAAGTGTATCATATGCCAAGTCCGCCCCCTATTGACGTCAATGA CGGTAAATGGCCCGCCTGGCATTATGCCCAGTACATGACCTTACGGGACTTTCCTACTTG GCAGTACATCTACGTATTAGTCATCGCTATTACCATGGTGATGCGGTTTTGGCAGTACAC CAATGGGCGTGGATAGCGGTTTGACTCACGGGGATTTCCAAGTCTCCACCCCATTGACGT CAATGGGAGTTTGTTTTGGCACCAAAATCAACGGGACTTTCCAAAATGTCGTAATAACCC CGCCCCGTTGACGCAAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGC TGGTTTAGTGAACCGTCAGATCACTAGAAGCTTTATTGCGGTAGTTTATCACAGTTAAAT TGCTAACGCAGTCAGTGCTTCTGACACAACAGTCTCGAACTTAAGCTGCAGAAGTTGGTC GTGAGGCACTGGGCAGGTAAGTATCAAGGTTACAAGACAGGTTTAAGGAGACCAATAGAA ACTGGGCTTGTCGAGACAGAGAAGACTCTTGCGTTTCTGATAGGCACCTATTGGTCTTAC TGACATCCACTTTGCCTTTCTCTCCACAGGTGTCCACTCCCAGTTCAATTACAGCTCTTA AGGCTAGAGTATTAATACGACTCACTATAGGGCTAGCAAAGCCACCATGGCAGAAATCGG TACTGGCTTTCCATTCGACCCCCATTATGTGGAAGTCCTGGGCGAGCGCATGCACTACGT CGATGTTGGTCCGCGCGATGGCACCCCTGTGCTGTTCCTGCACGGTAACCCGACCTCCTC CTACGTGTGGCGCAACATCATCCCGCATGTTGCACCGACCCATCGCTGCATTGCTCCAGA CCTGATCGGTATGGGCAAATCCGACAAACCAGACCTGGGTTATTTCTTCGACGACCACGT CCGCTTCATGGATGCCTTCATCGAAGCCCTGGGTCTGGAAGAGGTCGTCCTGGTCATTCA CGACTGGGGCTCCGCTCTGGGTTTCCACTGGGCCAAGCGCAATCCAGAGCGCGTCAAAGG TATTGCATTTATGGAGTTCATCCGCCCTATCCCGACCTGGGACGAATGGCCAGAATTTGC CCGCGAGACCTTCCAGGCCTTCCGCACCACCGACGTCGGCCGCAAGCTGATCATCGATCA GAACGTTTTTATCGAGGGTACGCTGCCGATGGGTGTCGTCCGCCCGCTGACTGAAGTCGA GATGGACCATTACCGCGAGCCGTTCCTGAATCCTGTTGACCGCGAGCCACTGTGGCGCTT CCCAAACGAGCTGCCAATCGCCGGTGAGCCAGCGAACATCGTCGCGCTGGTCGAAGAATA CATGGACTGGCTGCACCAGTCCCCTGTCCCGAAGCTGCTGTTCTGGGGCACCCCAGGCGT TCTGATCCCACCGGCCGAAGCCGCTCGCCTGGCCAAAAGCCTGCCTAACTGCAAGGCTGT GGACATCGGCCCGGGTCTGAATCTGCTGCAAGAAGACAACCCGGACCTGATCGGCAGCGA GATCGCGCGCTGGCTGTCGACGCTCGAGATTTCCGGCGAGCCAACCACTGAGGATCTGTA CTTTCAGAGCGATAACGCGATCGCCATGTGGATACTGGCTCTCTCCTTGTTCCAGAGCTT CGCGAATGTTTTCAGTGAAGACCTACACTCCAGCCTCTACTTTGTCAATGCATCTCTGCA AGAGGTAGTGTTTGCCAGCACCACGGGGACTCTGGTGCCCTGCCCCGCAGCAGGCATCCC TCCTGTGACTCTCAGATGGTACCTAGCCACGGGCGAGGAGATCTACGATGTCCCCGGGAT CCGCCACGTCCACCCCAACGGCACTCTCCAAATTTTCCCCTTCCCTCCTTCAAGCTTCAG TACCTTAATCCATGATAATACTTATTATTGCACAGCTGAAAATCCTTCAGGGAAAATTAG AAGTCAGGATGTCCACATCAAGGCTGTTTTACGGGAGCCCTATACAGTCCGTGTGGAGGA CCAGAAAACCATGAGAGGCAATGTTGCGGTCTTCAAGTGCATTATCCCCTCCTCGGTGGA GGCGTACATCACTGTCGTCTCATGGGAGAAAGACACTGTTTCACTTGTCTCAGGATCTAG ATTTCTCATCACATCCACGGGAGCCTTGTATATTAAAGATGTACAGAATGAAGATGGATT GTATAACTACCGCTGCATCACGCGGCATCGATACACCGGAGAGACGAGGCAGAGCAACAG CGCCAGACTTTTTGTATCAGACCCAGCGAACTCAGCCCCATCCATACTGGATGGGTTTGA GCATCGCAAAGCCATGGCTGGGCAGCGTGTGGAGCTGCCTTGCAAAGCGCTCGGGCACCC TGAGCCAGATTACCGCTGGCTGAAGGACAACATGCCCCTGGAACTTTCAGGGAGGTTCCA GAAGACCGTGACGGGGCTGCTCATTGAGAACATTCGCCCCTCGGACTCAGGCAGCTATGT TTGTGAAGTGTCCAACAGATACGGAACTGCTAAGGTGATAGGCCGCCTGTACGTGAAACA GCCACTGAAAGCCACCATCAGTCCCAGGAAGGTTAAAAGCAGCGTGGGTAGCCAAGTTTC CTTGTCCTGCAGCGTGACAGGAACTGAGGACCAGGAACTCTCCTGGTACCGCAATGGTGA AATCCTCAACCCTGGAAAAAATGTGAGGATCACAGGGATCAACCACGAAAACCTTATAAT GGATCACATGGTCAAAAGTGACGGGGGCGCATACCAGTGCTTTGTGCGCAAGGACAAGCT GTCCGCTCAAGACTATGTGCAGGTGGTCCTTGAAGATGGAACTCCCAAAATTATTTCTGC CTTTAGTGAAAAGGTGGTGAGTCCAGCAGAGCCGGTTTCCCTTATGTGCAACGTGAAGGG AACACCTTTGCCCACGATCACGTGGACCCTGGACGATGACCCGATTCTCAAGGGTGGCAG TCACCGCATCAGCCAGATGATCACGTCGGAGGGGAACGTGGTCAGCTACCTGAACATCTC CAGCTCCCAGGTCCGGGACGGGGGAGTCTACCGCTGCACTGCCAACAACTCGGCGGGAGT CGTCCTGTACCAGGCTCGAATAAACGTAAGAGGGCCTGCAAGCATTCGACCAATGAAAAA CATCACAGCAATAGCAGGACGGGACACATACATTCACTGTCGTGTGATTGGCTATCCGTA TTACTCCATTAAATGGTACAAGAACTCTAACCTGCTTCCTTTCAACCACCGCCAAGTGGC ATTTGAGAACAATGGAACTCTTAAACTTTCAGATGTGCAAAAGGAAGTGGACGAGGGGGA GTACACGTGCAACGTGTTGGTTCAACCACAACTCTCCACCAGCCAGAGCGTCCACGTGAC CGTGAAAGTTCCGCCTTTCATACAACCCTTTGAGTTTCCAAGATTCTCCATTGGGCAGCG GGTCTTCATCCCCTGTGTTGTGGTCTCAGGGGACTTACCCATCACGATCACCTGGCAGAA GGATGGCCGGCCAATCCCTGGGAGCCTTGGGGTGACCATTGACAATATTGACTTCACGAG CTCCTTGAGGATTTCCAATCTCTCGCTCATGCACAATGGGAATTACACCTGCATAGCCCG GAATGAGGCCGCCGCTGTGGAGCACCAAAGCCAGTTGATTGTCAGAGTTCCTCCCAAGTT TGTGGTTCAGCCACGGGACCAGGACGGGATTTATGGCAAAGCAGTCATCCTCAATTGTTC TGCTGAGGGTTACCCTGTACCTACCATCGTGTGGAAATTCTCTAAAGGTGCTGGGGTTCC CCAGTTCCAGCCAATTGCCCTAAATGGCCGAATCCAAGTTCTCAGCAATGGGTCGTTGCT GATCAAGCATGTCGTGGAGGAAGACAGTGGCTACTACCTCTGCAAGGTCAGCAACGATGT GGGCGCAGACGTCAGCAAGTCCATGTACCTCACGGTTAAAATTCCTGCGATGATAACATC CTATCCAAATACTACCCTGGCCACGCAGGGGCAGAAAAAGGAGATGAGCTGCACGGCGCA TGGTGAGAAGCCCATTATAGTCCGCTGGGAGAAGGAGGACCGAATCATTAACCCTGAGAT GGCCCGTTATCTTGTGTCCACCAAGGAGGTGGGAGAAGAGGTGATTTCTACTCTGCAGAT TTTGCCAACTGTGAGAGAAGATTCTGGTTTCTTTTCCTGCCATGCTATTAATTCTTATGG GGAGGACCGTGGAATAATTCAGCTCACAGTGCAAGAGCCCCCAGACCCTCCCGAAATTGA GATCAAAGATGTCAAAGCACGCACAATTACGCTCAGGTGGACCATGGGGTTTGATGGAAA CAGTCCCATCACAGGCTACGATATTGAATGCAAAAATAAATCAGACTCCTGGGATTCTGC TCAGAGAACCAAAGATGTTTCCCCTCAGCTGAACTCGGCCACCATCATTGATATCCACCC TTCCTCCACCTACAGCATCCGCATGTACGCCAAGAACCGGATTGGCAAGAGCGAGCCCAG CAACGAGCTCACCATCACGGCGGACGAGGCAGCTCCTGATGGTCCACCTCAGGAAGTTCA CCTGGAGCCTATATCATCTCAGAGCATCAGGGTCACATGGAAGGCTCCCAAGAAACATTT GCAAAATGGGATTATCCGTGGCTACCAAATAGGTTACCGAGAGTACAGCACTGGGGGTAA CTTCCAATTCAACATTATCAGTGTCGACACCAGCGGGGACAGTGAGGTTTACACCCTGGA CAACCTGAATAAGTTCACTCAGTACGGCCTGGTGGTGCAGGCCTGTAACCGGGCCGGCAC GGGGCCTTCTTCTCAGGAAATCATCACCACCACTCTCGAGGATGTGCCCAGTTACCCCCC CGAAAATGTCCAAGCCATAGCAACATCACCAGAAAGCATATCAATATCCTGGTCCACACT TTCCAAGGAAGCCTTGAATGGAATTCTCCAGGGGTTCAGAGTCATTTACTGGGCCAACCT CATGGACGGAGAGCTGGGTGAGATTAAAAACATCACCACCACACAGCCTTCACTGGAGCT GGACGGGCTGGAAAAGTACACCAACTACAGCATCCAGGTGCTGGCCTTCACCCGCGCAGG AGACGGGGTCAGGAGTGAGCAGATCTTCACCCGGACCAAAGAGGATGTTCCAGGTCCTCC CGCGGGTGTGAAGGCAGCGGCGGCCTCAGCCTCCATGGTCTTTGTGTCCTGGCTTCCCCC TCTCAAGCTGAACGGCATCATCCGAAAGTACACTGTATTCTGCTCCCACCCCTATCCCAC AGTGATCAGCGAGTTTGAGGCCTCTCCCGACTCGTTTTCCTACAGAATTCCCAACCTGAG TAGGAATCGTCAGTACAGCGTCTGGGTGGTGGCTGTTACTTCAGCCGGAAGAGGCAACAG CAGTGAAATCATCACAGTTGAGCCACTAGCAAAAGCTCCTGCACGAATCCTGACCTTCAG TGGGACAGTGACTACTCCATGGATGAAAGACATTGTCTTGCCTTGTAAGGCTGTTGGGGA CCCTTCTCCTGCAGTCAAATGGATGAAAGACAGTAACGGGACACCCAGTCTAGTAACGAT TGATGGGCGGAGGAGCATCTTTAGCAACGGAAGCTTCATTATTCGCACGGTGAAAGCAGA AGACTCCGGCTATTACAGCTGCATTGCCAATAACAACTGGGGATCTGATGAAATTATTTT AAACTTACAAGTACAAGTTCCACCAGATCAGCCTCGGCTTACAGTCTCCAAGACCACGTC TTCCTCCATCACCCTTTCTTGGCTCCCTGGAGACAACGGGGGCAGCTCTATCAGAGGATA CATACTGCAGTACTCCGAGGACAATAGTGAGCAGTGGGGGAGTTTTCCAATCAGCCCCAG CGAACGTTCCTATCGCTTGGAAAATCTCAAATGTGGGACTTGGTATAAGTTCACACTGAC AGCCCAAAATGGAGTGGGCCCAGGGCGCATAAGTGAAATCATAGAAGCAAAGACCTTAGG AAAAGAGCCCCAGTTCTCAAAGGAGCAGGAGCTGTTTGCCAGCATCAACACCACACGCGT GAGGCTGAACCTCATTGGCTGGAATGATGGCGGCTGCCCCATCACCTCCTTCACACTAGA GTACAGGCCCTTTGGGACCACAGTTTGGACCACAGCTCAGAGGACCTCTCTCTCCAAGTC CTACATCCTGTATGACCTGCAGGAAGCCACCTGGTATGAGCTGCAGATGCGGGTGTGCAA CAGTGCGGGCTGCGCGGAGAAGCAGGCCAACTTCGCTACGCTGAACTACGATGGCAGTAC AATTCCTCCACTCATTAAGTCAGTTGTCCAAAACGAAGAAGGGCTGACGACCAACGAGGG GCTCAAGATGCTGGTGACCATCTCCTGTATCCTGGTGGGGGTCTTGCTGCTGTTTGTGCT CCTGCTGGTTGTGCGGAGGAGGCGGCGGGAGCAGAGGCTAAAGAGGCTGCGAGATGCAAA GAGTTTAGCTGAAATGCTCATGAGTAAGAATACCCGGACTTCAGATACGTTAAGCAAGCA ACAGCAGACCCTGCGAATGCACATCGACATACCCAGGGCTCAGCTTTTGATTGAAGAGAG AGACACGATGGAGACCATTGATGATCGCTCCACGGTTCTGTTGACGGATGCTGACTTTGG AGAGGCAGCTAAGCAGAAGTCCCTGACGGTCACTCACACGGTCCATTACCAATCGGTGTC TCAGGCCACTGGGCCCTTAGTGGATGTTTCAGACGCTCGGCCGGGAACGAATCCCACCAC CAGGAGGAATGCCAAGGCTGGGCCCACAGCGAGAAACCGCTATGCCAGCCAGTGGACCCT CAACCGACCCCACCCCACCATCTCAGCACACACCCTCACCACAGACTGGAGGCTGCCAAC ACCCAGGGCTGCAGGATCAGTAGACAAAGAGAGCGACAGTTACAGCGTCAGCCCCTCGCA AGACACAGATCGAGCAAGAAGCAGCATGGTCTCCACAGAAAGTGCCTCCTCCACTTACGA AGAACTGGCCAGGGCCTACGAACACGCCAAGATGGAAGAGCAACTGAGGCACGCCAAGTT CACCATCACGGAGTGCTTCATATCAGACACGTCATCGGAGCAGTTGACGGCAGGGACAAA TGAGTACACGGACAGTCTGACCTCCAGCACCCCTTCCGAATCGGGAATCTGCAGGTTCAC TGCATCTCCCCCCAAACCTCAGGATGGAGGAAGAGTAATGAATATGGCAGTTCCAAAGGC ACATCGGCCAGGTGACCTCATACATTTGCCTCCATACCTTAGAATGGACTTTTTGTTAAA CCGAGGTGGTCCAGGCACCAGCAGGGACCTGAGCTTAGGACAAGCATGCTTGGAACCTCA GAAAAGCCGGACCCTGAAGCGCCCCACGGTCCTGGAGCCCATCCCGATGGAAGCCGCCTC CTCCGCCTCCTCCACGAGAGAAGGACAGTCGTGGCAGCCGGGGGCCGTGGCCACATTACC TCAGCGGGAGGGAGCAGAGCTGGGACAGGCAGCTAAAATGAGCAGCTCCCAAGAATCACT GCTCGACTCCCGGGGCCATTTGAAAGGAAACAATCCTTACGCAAAATCTTACACCCTGGT AGTTTAAACGAATTCGGGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGC AAGCTGATCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTG AGCAATAACTAGCATAACCCCTTGGGGCGGCCGCTTCGAGCAGACATGATAAGATACATT GATGAGTTTGGACAAACCACAACTAGAATGCAGTGAAAAAAATGCTTTATTTGTGAAATT TGTGATGCTATTGCTTTATTTGTAACCATTATAAGCTGCAATAAACAAGTTAACAACAAC AATTGCATTCATTTTATGTTTCAGGTTCAGGGGGAGATGTGGGAGGTTTTTTTAAGCAAG TAAAACCTCTACAAATGTGGTAAAATCGAATTCTAATGGATCCTCTTTGCGCTTGCGTTT TCCCTTGTCCAGATAGCCCAGTAGCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGA CTGGCTTTCTACGTAATGGTTTCTTAGACGTCAGGTGGCACTTTTCGGGGAAATGTGCGC GGAACCCCTATTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCATGAGACAA TAACCCTGATAAATGCTTCAATAATATTGAAAAAGGAAGAGTATGAGTATTCAACATTTC CGTGTCGCCCTTATTCCCTTTTTTGCGGCATTTTGCCTTCCTGTTTTTGCTCACCCAGAA ACGCTGGTGAAAGTAAAAGATGCTGAAGATCAGTTGGGTGCACGAGTGGGTTACATCGAA CTGGATCTCAACAGCGGTAAGATCCTTGAGAGTTTTCGCCCCGAAGAACGTTTTCCAATG ATGAGCACTTTCAAAGTTCTGCTATGTGGCGCGGTATTATCCCGTATTGACGCCGGGCAA GAGCAACTCGGTCGCCGCATACACTATTCTCAGAATGACTTGGTTGAGTACTCACCAGTC ACAGAAAAGCATCTTACGGATGGCATGACAGTAAGAGAATTATGCAGTGCTGCCATAACC ATGAGTGATAACACTGCGGCCAACTTACTTCTGACAACTATCGGAGGACCGAAGGAGCTA ACCGCTTTTTTGCACAACATGGGGGATCATGTAACTCGCCTTGATCGTTGGGAACCGGAG CTGAATGAAGCCATACCAAACGACGAGCGTGACACCACGATGCCTGTAGCAATGGCAACA ACGTTGCGCAAACTATTAACTGGCGAACTACTTACTCTAGCTTCCCGGCAACAATTAATA GACTGGATGGAGGCGGATAAAGTTGCAGGACCACTTCTGCGCTCGGCCCTTCCGGCTGGC TGGTTTATTGCTGATAAATCTGGAGCCGGTGAGCGTGGGTCTCGCGGTATCATTGCAGCA CTGGGGCCAGATGGTAAGCCCTCCCGTATCGTAGTTATCTACACGACGGGGAGTCAGGCA ACTATGGATGAACGAAATAGACAGATCGCTGAGATAGGTGCCTCACTGATTAAGCATTGG TAATTCGAAATGACCGACCAAGCGACGCCCAACCGGTATCAGCTCACTCAAAGGCGGTAA TACGGTTATCCACAGAATCAGGGGATAACGCAGGAAAGAACATGTGAGCAAAAGGCCAGC AAAAGGCCAGGAACCGTAAAAAGGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCC CTGACGAGCATCACAAAAATCGACGCTCAAGTCAGAGGTGGCGAAACCCGACAGGACTAT AAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGC CGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCT CACGCTGTAGGTATCTCAGTTCGGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACG AACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACC CGGTAAGACACGACTTATCGCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGA GGTATGTAGGCGGTGCTACAGAGTTCTTGAAGTGGTGGCCTAACTACGGCTACACTAGAA GGACAGTATTTGGTATCTGCGCTCTGCTGAAGCCAGTTACCTTCGGAAAAAGAGTTGGTA GCTCTTGATCCGGCAAACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGC AGATTACGCGCAGAAAAAAAGGATTTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTG ACGCTCAGTGGAACGAAAACTCACGTTAAGGGATTTTGGTCATGAGATTATCAAAAAGGA TCTTCACCTAGATCCTTTTATAGTCCGGAAATACAGGAACGCACGCTGGATGGCCCTTCG CTGGGATGGTGAAACCATGAAAAATGGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGC CTGTACCCTCTGGTTGCATAGGTATTCATACGGTTAAAATTTATCAGGCGCGATTGCGGC AGTTTTTCGGGTGGTTTGTTGCCATTTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGC GTTTTAGCGGTGCGTACAATTAAGGGATTATGGTAAATCCACTTACTGTCTGCCCTCGTA GCCATCGAGATAAACCGCAGTACTCCGGCCACGATGCGTCCGGCGTAGAGGATCGAGATC T
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