-
SpecieshumanProduct IDFXC01882Cloning SiteSgfI-PmeIGeneKIBB9460SymbolPIK3R2
Alias : MPPH, MPPH1, P85B, p85, p85-BETADescriptionphosphoinositide-3-kinase, regulatory subunit 2 (beta), transcript variant 1Original Clone IDfk10876
Length: 2184 bp
Restriction map A
Restriction map B
Genomic Structure
-
Length: 728 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS12371.1 7.4e-140 99.7 PIK3R2 CCDS3993.1 1.6e-73 59.6 PIK3R1 CCDS3995.1 1.3e-59 76.0 PIK3R1 CCDS3994.1 9.5e-59 76.1 PIK3R1 CCDS529.1 2.5e-58 72.5 PIK3R3
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ]
Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR001720 324 342 PR00678 PI3 kinase IPR001720 381 395 PR00678 PI3 kinase IPR001720 420 443 PR00678 PI3 kinase IPR001720 483 501 PR00678 PI3 kinase IPR001720 502 524 PR00678 PI3 kinase IPR001720 554 573 PR00678 PI3 kinase IPR001720 574 599 PR00678 PI3 kinase IPR000980 622 636 PR00401 SH2 motif IPR001720 628 650 PR00678 PI3 kinase IPR000980 641 651 PR00401 SH2 motif IPR000980 652 663 PR00401 SH2 motif IPR001720 653 670 PR00678 PI3 kinase IPR001720 673 698 PR00678 PI3 kinase IPR000980 685 699 PR00401 SH2 motif HMMPfam IPR000198 125 259 PF00620 Rho GTPase-activating protein domain IPR000980 330 405 PF00017 SH2 motif IPR000980 622 696 PF00017 SH2 motif HMMSmart IPR001452 7 79 SM00326 Src homology-3 domain IPR000198 122 292 SM00324 Rho GTPase-activating protein domain IPR000980 328 411 SM00252 SH2 motif IPR000980 620 702 SM00252 SH2 motif ProfileScan IPR001452 4 80 PS50002 Src homology-3 domain IPR000198 109 295 PS50238 Rho GTPase-activating protein domain IPR000980 330 425 PS50001 SH2 motif IPR000980 622 716 PS50001 SH2 motif
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_005018 728 603157,603387 100.0 100.0 XP_005248599 724 171833,269880,615214,616005 59.6 98.1 NP_852664 724 171833,269880,615214,616005 59.6 98.1 XP_016865074 724 171833,269880,615214,616005 59.6 98.1 XP_016865075 633 171833,269880,615214,616005 61.7 84.2 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB9460 Download>KIBB9460 2184 bp ATGGCGGGCCCTGAGGGCTTCCAGTACCGCGCTCTGTACCCGTTCCGCCGGGAGCGGCCG GAGGACCTGGAGCTGCTGCCCGGCGACGTGCTGGTAGTGAGCCGGGCGGCCTTGCAGGCG CTGGGCGTGGCCGAGGGTGGCGAGCGCTGCCCACAGAGCGTGGGCTGGATGCCCGGCCTC AACGAGCGCACACGGCAGCGAGGTGACTTCCCTGGCACCTATGTGGAGTTCCTGGGGCCC GTGGCCCTGGCCCGGCCCGGCCCTCGCCCACGGGGCCCCCGCCCACTGCCCGCCAGGCCC CGTGATGGGGCCCCTGAGCCAGGCCTCACACTCCCCGACTTGCCCGAGCAGTTCTCCCCA CCTGATGTGGCTCCCCCTCTTCTGGTGAAGCTTGTGGAGGCCATTGAAAGGACAGGGCTG GACAGCGAATCTCACTACCGCCCGGAGCTGCCCGCACCGCGTACAGACTGGTCCCTGAGC GACGTGGATCAGTGGGACACGGCAGCCCTGGCTGACGGCATTAAGAGCTTCCTGCTGGCA CTGCCCGCGCCGCTCGTGACCCCCGAGGCCTCGGCCGAGGCGCGCCGGGCCCTGCGGGAG GCCGCGGGGCCCGTGGGGCCGGCGCTGGAGCCACCGACGCTGCCGCTGCACCGCGCGCTC ACGCTGCGCTTCCTGCTCCAGCACCTGGGCCGCGTGGCCCGCCGCGCCCCGGCCCTGGGT CCCGCGGTCCGGGCCCTGGGCGCCACCTTTGGGCCGCTGCTGCTGCGCGCGCCGCCGCCG CCGTCCTCGCCGCCGCCAGGGGGCGCTCCCGACGGGAGTGAGCCCAGCCCTGACTTCCCG GCGCTGCTGGTGGAGAAGCTGCTTCAGGAACACTTGGAAGAGCAGGAGGTTGCGCCCCCA GCGCTGCCGCCTAAACCCCCCAAGGCAAAGCCGGCCCCCACAGTCCTGGCCAATGGAGGG AGCCCACCCTCCCTGCAGGATGCTGAGTGGTACTGGGGGGACATTTCAAGGGAGGAGGTG AACGAGAAACTCCGGGACACTCCCGATGGCACCTTCCTAGTCCGAGATGCTTCTAGCAAG ATCCAGGGCGAGTACACGCTGACCCTCAGGAAAGGCGGGAACAATAAGCTGATCAAGGTC TTCCACCGAGATGGGCACTATGGCTTCTCAGAGCCACTCACCTTCTGCTCCGTTGTGGAC CTCATCAATCACTACCGCCACGAGTCTCTGGCCCAGTACAATGCCAAGCTGGACACACGG CTCCTCTACCCTGTGTCCAAATACCAGCAGGACCAGATTGTCAAGGAGGACAGCGTGGAG GCAGTGGGCGCCCAGCTTAAGGTCTATCACCAGCAGTACCAGGACAAGAGCCGCGAGTAT GACCAGCTTTATGAAGAGTACACACGGACCTCCCAGGAGCTGCAGATGAAGCGTACTGCA ATTGAGGCCTTCAATGAGACTATCAAGATCTTTGAAGAGCAGGGCCAGACTCAAGAGAAA TGCAGCAAGGAATACCTGGAGCGCTTCCGGCGTGAGGGCAACGAGAAAGAGATGCAAAGG ATCCTGCTGAACTCCGAGCGGCTCAAGTCCCGCATTGCCGAGATCCATGAGAGCCGCACG AAGCTGGAGCAGCAGCTGCGGGCCCAGGCCTCGGACAACAGAGAGATCGACAAGCGCATG AACAGCCTCAAGCCGGACCTCATGCAGCTGCGCAAGATCCGAGACCAGTACCTCGTGTGG CTCACCCAGAAAGGCGCCCGGCAGAAGAAAATCAACGAGTGGCTGGGGATTAAAAATGAG ACTGAGGACCAGTACGCACTCATGGAGGACGAGGACGATCTCCCGCACCACGAGGAACGC ACTTGGTACGTGGGCAAGATCAACCGCACGCAGGCAGAGGAGATGCTGAGCGGCAAGCGG GATGGCACCTTCCTCATCCGCGAGAGCAGCCAGCGGGGCTGCTACGCCTGCTCCGTGGTA GTGGACGGCGACACCAAGCACTGCGTCATCTACCGCACGGCCACCGGCTTCGGCTTCGCG GAGCCCTACAACCTGTACGGGTCGCTGAAGGAGCTGGTGCTGCACTACCAGCACGCCTCG CTGGTGCAGCACAACGACGCGCTCACCGTCACCCTGGCGCACCCAGTGCGCGCCCCGGGC CCCGGCCCGCCGCCTGCCGCCCGC
Cloned ORF protein sequence for pF1KB9460 Download>KIBB9460 728 aa MAGPEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQALGVAEGGERCPQSVGWMPGL NERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPRDGAPEPGLTLPDLPEQFSP PDVAPPLLVKLVEAIERTGLDSESHYRPELPAPRTDWSLSDVDQWDTAALADGIKSFLLA LPAPLVTPEASAEARRALREAAGPVGPALEPPTLPLHRALTLRFLLQHLGRVARRAPALG PAVRALGATFGPLLLRAPPPPSSPPPGGAPDGSEPSPDFPALLVEKLLQEHLEEQEVAPP ALPPKPPKAKPAPTVLANGGSPPSLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSK IQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTR LLYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTA IEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRT KLEQQLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNE TEDQYALMEDEDDLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVV VDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPG PGPPPAAR
Nucleotide Sequence (with vector) for pF1KB9460 Download>pF1KB9460 5297 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGGCGGGCCCT GAGGGCTTCCAGTACCGCGCTCTGTACCCGTTCCGCCGGGAGCGGCCGGAGGACCTGGAG CTGCTGCCCGGCGACGTGCTGGTAGTGAGCCGGGCGGCCTTGCAGGCGCTGGGCGTGGCC GAGGGTGGCGAGCGCTGCCCACAGAGCGTGGGCTGGATGCCCGGCCTCAACGAGCGCACA CGGCAGCGAGGTGACTTCCCTGGCACCTATGTGGAGTTCCTGGGGCCCGTGGCCCTGGCC CGGCCCGGCCCTCGCCCACGGGGCCCCCGCCCACTGCCCGCCAGGCCCCGTGATGGGGCC CCTGAGCCAGGCCTCACACTCCCCGACTTGCCCGAGCAGTTCTCCCCACCTGATGTGGCT CCCCCTCTTCTGGTGAAGCTTGTGGAGGCCATTGAAAGGACAGGGCTGGACAGCGAATCT CACTACCGCCCGGAGCTGCCCGCACCGCGTACAGACTGGTCCCTGAGCGACGTGGATCAG TGGGACACGGCAGCCCTGGCTGACGGCATTAAGAGCTTCCTGCTGGCACTGCCCGCGCCG CTCGTGACCCCCGAGGCCTCGGCCGAGGCGCGCCGGGCCCTGCGGGAGGCCGCGGGGCCC GTGGGGCCGGCGCTGGAGCCACCGACGCTGCCGCTGCACCGCGCGCTCACGCTGCGCTTC CTGCTCCAGCACCTGGGCCGCGTGGCCCGCCGCGCCCCGGCCCTGGGTCCCGCGGTCCGG GCCCTGGGCGCCACCTTTGGGCCGCTGCTGCTGCGCGCGCCGCCGCCGCCGTCCTCGCCG CCGCCAGGGGGCGCTCCCGACGGGAGTGAGCCCAGCCCTGACTTCCCGGCGCTGCTGGTG GAGAAGCTGCTTCAGGAACACTTGGAAGAGCAGGAGGTTGCGCCCCCAGCGCTGCCGCCT AAACCCCCCAAGGCAAAGCCGGCCCCCACAGTCCTGGCCAATGGAGGGAGCCCACCCTCC CTGCAGGATGCTGAGTGGTACTGGGGGGACATTTCAAGGGAGGAGGTGAACGAGAAACTC CGGGACACTCCCGATGGCACCTTCCTAGTCCGAGATGCTTCTAGCAAGATCCAGGGCGAG TACACGCTGACCCTCAGGAAAGGCGGGAACAATAAGCTGATCAAGGTCTTCCACCGAGAT GGGCACTATGGCTTCTCAGAGCCACTCACCTTCTGCTCCGTTGTGGACCTCATCAATCAC TACCGCCACGAGTCTCTGGCCCAGTACAATGCCAAGCTGGACACACGGCTCCTCTACCCT GTGTCCAAATACCAGCAGGACCAGATTGTCAAGGAGGACAGCGTGGAGGCAGTGGGCGCC CAGCTTAAGGTCTATCACCAGCAGTACCAGGACAAGAGCCGCGAGTATGACCAGCTTTAT GAAGAGTACACACGGACCTCCCAGGAGCTGCAGATGAAGCGTACTGCAATTGAGGCCTTC AATGAGACTATCAAGATCTTTGAAGAGCAGGGCCAGACTCAAGAGAAATGCAGCAAGGAA TACCTGGAGCGCTTCCGGCGTGAGGGCAACGAGAAAGAGATGCAAAGGATCCTGCTGAAC TCCGAGCGGCTCAAGTCCCGCATTGCCGAGATCCATGAGAGCCGCACGAAGCTGGAGCAG CAGCTGCGGGCCCAGGCCTCGGACAACAGAGAGATCGACAAGCGCATGAACAGCCTCAAG CCGGACCTCATGCAGCTGCGCAAGATCCGAGACCAGTACCTCGTGTGGCTCACCCAGAAA GGCGCCCGGCAGAAGAAAATCAACGAGTGGCTGGGGATTAAAAATGAGACTGAGGACCAG TACGCACTCATGGAGGACGAGGACGATCTCCCGCACCACGAGGAACGCACTTGGTACGTG GGCAAGATCAACCGCACGCAGGCAGAGGAGATGCTGAGCGGCAAGCGGGATGGCACCTTC CTCATCCGCGAGAGCAGCCAGCGGGGCTGCTACGCCTGCTCCGTGGTAGTGGACGGCGAC ACCAAGCACTGCGTCATCTACCGCACGGCCACCGGCTTCGGCTTCGCGGAGCCCTACAAC CTGTACGGGTCGCTGAAGGAGCTGGTGCTGCACTACCAGCACGCCTCGCTGGTGCAGCAC AACGACGCGCTCACCGTCACCCTGGCGCACCCAGTGCGCGCCCCGGGCCCCGGCCCGCCG CCTGCCGCCCGCGTTTAAACGAATTCGAGCTCGGTACCCGGGGATCCTCTAGAGTCGACC TGCAGGCATGCAAGCTGATCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGC TGCCACCGCTGAGCAATAACTAGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGG TTTTTTGCTGAAAGGAGGAACTATATCCGGTTCGCTTGCTGTCCATAAAACCGCCCAGTC TAGCTATCGCCATGTAAGCCCACTGCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTC CCTTGTCCAGATAGCCCAGTAGCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGACT GGCTTTCTACGTGTTCCGCTTCCTTTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCG TGAGCTTCAAAAGAATTGCCAGCTGGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAA GTAAACTGGATGGCTTTCTTGCCGCCAAGGATCTGATGGCGCAGGGGATCAAGATCTGAT CAAGAGACAGGATGACGGTCGTTTCGCATGCTTGAACAAGATGGATTGCACGCAGGTTCT CCGGCCGCTTGGGTGGAGAGGCTATTCGGCTATGACTGGGCACAACAGACAATCGGCTGC TCTGATGCCGCCGTGTTCCGGCTGTCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACC GACCTGTCCGGTGCCCTGAATGAACTGCAGGACGAGGCAGCGCGGCTATCGTGGCTGGCC ACGACGGGCGTTCCTTGCGCAGCTGTGCTCGACGTTGTCACTGAAGCGGGAAGGGACTGG CTGCTATTGGGCGAAGTGCCGGGGCAGGATCTCCTGTCATCTCACCTTGCTCCTGCCGAG AAAGTATCCATCATGGCTGATGCAATGCGGCGGCTGCATACGCTTGATCCGGCTACCTGC CCATTCGACCACCAAGCGAAACATCGCATCGAGCGAGCACGCACTCGGATGGAAGCCGGT CTTGTCGATCAGGATGATCTGGACGAAGAGCATCAGGGGCTCGCGCCAGCCGAACTGTTC GCCAGGCTCAAGGCGCGTATGCCGGATGGTGAGGATCTCGTCGTGACTCATGGCGATGCC TGCTTGCCGAATATCATGGTGGAAAATGGCCGCTTTTCTGGATTCATCGACTGTGGCCGG CTGGGTGTGGCGGACCGCTATCAGGACATAGCGTTGGCTACCCGTGATATTGCTGAAGAG CTTGGCGGCGAATGGGCTGACCGCTTCCTCGTGCTTTACGGTATCGCCGCTCCCGATTCG CAGCGCATCGCCTTCTATCGCCTTCTTGACGAGTTCTTCTGAGCGGGACTCTGGGGTTCG AAATGACCGACCAAGCGACGCCCAACCGGACTATAAAAGGATCTAGGTGAAGATCCTTTT TGATAATCTCATGACCAAAATCCCTTAACGTGAGTTTTCGTTCCACTGAGCGTCAGACCC CGTAGAAAAGATCAAAGGATCTTCTTGAAATCCTTTTTTTCTGCGCGTAATCTGCTGCTT GCAAACAAAAAAACCACCGCTACCAGCGGTGGTTTGTTTGCCGGATCAAGAGCTACCAAC TCTTTTTCCGAAGGTAACTGGCTTCAGCAGAGCGCAGATACCAAATACTGTCCTTCTAGT GTAGCCGTAGTTAGGCCACCACTTCAAGAACTCTGTAGCACCGCCTACATACCTCGCTCT GCTAATCCTGTTACCAGTGGCTGCTGCCAGTGGCGATAAGTCGTGTCTTACCGGGTTGGA CTCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACGGGGGGTTCGTGCAC ACAGCCCAGCTTGGAGCGAACGACCTACACCGAACTGAGATACCTACAGCGTGAGCTATG AGAAAGCGCCACGCTTCCCGAAGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGT CGGAACAGGAGAGCGCACGAGGGAGCTTCCAGGGGGAAACGCCTGGTATCTTTATAGTCC TGTCGGGTTTCGCCACCTCTGACTTGAGCGTCGATTTTTGTGATGCTCGTCAGGGGGGCG GAGCCTATGGAAAAACGCCAGCAACGCGGCCTTTTTACGGTTCCTGGCCTTTTGCTGGCC TTTTGCTCACATGTTCTTTCCTGCGTTATCCCCTGATTCTGTGGATAACCGTATTACCGC CTTTGAGTGAGCTGATACCGGAAATACAGGAACGCACGCTGGATGGCCCTTCGCTGGGAT GGTGAAACCATGAAAAATGGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACC CTCTGGTTGCATAGGTATTCATACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTT CGGGTGGTTTGTTGCCATTTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAG CGGTGCGTACAATTAAGGGATTATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCG AGATAAACCGCAGTACTCCGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCTTTTCAG CCTGATACAGATTAAATCAGAACGCAGAAGCGGTCTGATAAAACAGAATTTGCCTGGCGG CAGTAGCGCGGTGGTCCCACCTGACCCCATGCCGAACTCAGAAGTGAAACGCCGTAGCGC CGATGGTAGTGTGGGGTCTCCCCATGCGAGAGTAGGGAACTGCCAGGCATCAAATAAAAC GAAAGGCTCAGTCGAAAGACTGGGCCTTTCGTTTTATCTGTTGTTTGTCGGTGAACGCTC TCCTGAGTAGGACAAATCCGCCGGGAGCGGATTTGAACGTTGCGAAGCAACGGCCCGGAG GGTGGCGGGCAGGACGCCCGCCATAAACTGCCAGGCATCAAATTAAGCAGAAGGCCATCC TGACGGATGGCCTTTTTGCGTTTCTACAAACTCTTTTGTTTATTTTTCTAAATACATTCA AATATGTATCCGCTCAT
more Linker info
