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SpecieshumanProduct IDFHC01096Cloning SiteSgfI-PmeIGeneKIAA0580SymbolARAP2
Alias : CENTD1, PARXDescriptionArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2Original Clone IDhj00601s2
Characterization of the cloned ORF
N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand
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Length: 5112 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 1704 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS3441.1 0 99.9 ARAP2 CCDS8217.2 2.5e-136 41.7 ARAP1 CCDS41687.1 2.9e-136 41.7 ARAP1 CCDS44671.1 9.6e-89 40.0 ARAP1 CCDS4266.1 7.7e-82 40.5 ARAP3
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR001164 697 716 PR00405 Arf GTPase activating protein IPR001164 716 733 PR00405 Arf GTPase activating protein HMMPfam IPR021129 10 65 PF00536 Sterile alpha motif IPR001849 484 573 PF00169 Pleckstrin homology domain IPR001849 590 678 PF00169 Pleckstrin homology domain IPR001164 687 801 PF01412 Arf GTPase activating protein IPR001849 911 1000 PF00169 Pleckstrin homology domain IPR000198 1129 1278 PF00620 Rho GTPase-activating protein domain IPR000159 1329 1412 PF00788 Ras-association IPR001849 1436 1533 PF00169 Pleckstrin homology domain HMMSmart IPR001660 4 70 SM00454 Sterile alpha motif domain IPR001849 483 576 SM00233 Pleckstrin homology domain IPR001849 588 681 SM00233 Pleckstrin homology domain IPR001164 686 807 SM00105 Arf GTPase activating protein IPR001849 893 1005 SM00233 Pleckstrin homology domain IPR001849 1015 1114 SM00233 Pleckstrin homology domain IPR000198 1126 1302 SM00324 Rho GTPase-activating protein domain IPR001849 1435 1539 SM00233 Pleckstrin homology domain ProfileScan IPR001660 10 70 PS50105 Sterile alpha motif domain IPR001849 482 574 PS50003 Pleckstrin homology domain IPR001849 587 679 PS50003 Pleckstrin homology domain IPR001164 676 811 PS50115 Arf GTPase activating protein IPR001849 878 1003 PS50003 Pleckstrin homology domain IPR000198 1116 1297 PS50238 Rho GTPase-activating protein domain IPR000159 1326 1420 PS50200 Ras-association IPR001849 1434 1537 PS50003 Pleckstrin homology domain
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) XP_016863188 1704 606645 99.9 100.0 NP_056045 1704 606645 99.9 100.0 XP_016863187 1710 606645 99.9 92.8 XP_016863190 1659 606645 97.3 100.0 XP_016863191 1636 606645 96.0 100.0 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pFN21AA0580 Download>KIAA0580 5112 bp ATGTCCTCAGTCAGTGAAGTAAATGTGGATATAAAAGATTTCCTAATGAGCATTAATTTG GAGCAGTATCTCTTACATTTCCATGAGTCTGGTTTTACTACTGTGAAGGACTGTGCAGCA ATAAATGACAGCCTGCTGCAGAAAATTGGAATATCACCTACAGGTCACCGTAGGAGGATA CTTAAACAGTTACAGATAATCTTGTCAAAAATGCAAGATATTCCAATATATGCAAATGTT CATAAAACTAAGAAGAATGATGACCCTTCAAAGGATTACCATGTTCCATCTTCTGATCAG AATATCTGCATAGAACTTTCCAATTCTGGTAGTGTTCAGACATCTAGCCCACCGCAGTTG GAGACTGTTAGAAAAAATCTTGAAGACAGTGATGCAAGTGTGGAAAGAAGCCAGTATCCT CAATCAGATGATAAGCTGTCTCCTCCTAAACGCGACTTCCCCACTGCAGAGGAACCACAC CTGAATTTGGGTTCTTTGAATGATTCTTTATTTGGTAGTGACAATATTAAAATAGAATCA TTGATTACAAAGAAGACTGTGGATCACACAGTTGAAGAACAACAAACAGAAAAAGTTAAA TTGATCACAGAAAATCTCAGTAAGCTCCCTAATGCAGACTCTGAATGCCTTTCTTTTGTT GGCTGTTCAACATCAGGAACAAATTCTGGAAATGGAACAAATGGTTTATTAGAAGGATCA CCACCATCCCCATTCTTTAAGTTTCAAGGAGAAATGATTGTAAATGACTTGTATGTTCCA TCATCACCAATCCTAGCACCTGTGAGAAGTCGTAGCAAGTTGGTTTCAAGACCATCTCGA TCTTTTCTGCTAAGACATCGACCTGTACCAGAGATTCCAGGGTCAACAAAAGGAGTTTCT GGGAGCTATTTCCGTGAAAGAAGAAATGTTGCTACCTCAACTGAAAAATCTGTGGCATGG CAAAATTCAAATGAGGAGAATTCATCTTCCATCTTTCCTTATGGAGAGACCTTTCTCTTC CAGAGACTAGAAAATTCCAAGAAGCGATCTATAAAGAATGAATTTTTGACCCAGGGAGAA GCACTCAAAGGGGAAGCAGCTACTGCAACAAACTCTTTTATCATCAAATCAAGCATATAC GATAACAGAAAGGAGAAAATAAGCGAGGACAAGGTGGAAGATATTTGGATACCTCGAGAG GACAAAAACAATTTTTTGATAGACACTGCTTCTGAATCAGAATACTCAACAGTAGAAGAA TGCTTTCAGAGTTTAAGAAGAAAAAATTCAAAGGCATCTAAATCTAGGACTCAAAAAGCC TTGATTTTGGACTCCGTTAATAGGCACAGTTATCCGTTAAGCTCAACAAGTGGAAATGCT GATTCATCAGCCGTTTCTTCACAGGCAATATCTCCCTATGCCTGCTTTTATGGAGCATCT GCAAAGAAGGTTAAATCAGGATGGCTGGATAAACTCTCTCCTCAAGGAAAACGCATGTTT CAAAAGAGATGGGTGAAATTTGATGGCCTTAGCATTTCTTACTACAATAATGAGAAGGAG ATGTATTCGAAAGGAATAATTCCCCTTTCTGCTATATCAACAGTACGAGTTCAAGGAGAC AACAAATTTGAAGTTGTTACAACACAAAGAACTTTTGTTTTTAGAGTAGAAAAAGAAGAG GAGAGAAATGACTGGATCAGCATACTATTAAATGCACTGAAATCACAATCCCTTACCTCG CAGTCTCAAGCTGTTGTTACACCTGAGAAATGTGGATATCTTGAATTGAGAGGCTATAAG GCAAAAATTTTTACTGTGTTAAGTGGAAACAGTGTGTGGCTTTGCAAAAACGAACAGGAT TTTAAGAGTGGACTTGGTATTACCATAATTCCTATGAATGTAGCAAATGTAAAGCAAGTG GACCGAACTGTGAAACAATCTTTTGAAATAATCACTCCCTACAGGAGTTTCAGCTTTACA GCCGAGACTGAAAAGGAGAAACAAGACTGGATTGAAGCTGTGCAGCAATCAATAGCAGAA ACTCTCTCTGATTATGAAGTAGCTGAGAAGATTTGGTTCAATGAATCCAACAGGAGCTGT GCAGATTGTAAAGCCCCAGATCCTGACTGGGCATCCATCAATCTCTGTGTTGTCATCTGT AAGAAGTGTGCAGGACAGCATAGATCTTTAGGACCAAAAGATTCCAAGGTTAGAAGTCTA AAAATGGATGCTAGCATTTGGAGCAATGAACTCATCGAGCTTTTTATTGTCATTGGAAAC AAAAGAGCAAATGACTTTTGGGCTGGTAATCTTCAAAAGGATGAAGAATTACATATGGAC TCACCAGTAGAAAAGAGAAAAAACTTTATTACTCAGAAATATAAAGAAGGAAAATTCAGA AAAACTCTTTTGGCATCTCTCACCAAAGAAGAATTAAATAAGGCTCTATGTGCTGCTGTA GTGAAACCGGATGTTCTAGAAACAATGGCTTTGCTGTTCAGTGGAGCAGATGTCATGTGT GCCACCGGAGACCCCGTGCATAGCACCCCCTATCTGCTAGCCAAGAAAGCTGGGCAAAGT CTGCAAATGGAATTTCTCTACCATAACAAATTCTCAGATTTCCCTCAACATGATATTCAT TCCGAGGGTGTATTAAGTCAAGAGTCTTCCCAGTCCACATTCCTCTGTGACTTTTTATAT CAAGCTCCTTCTGCTGCTTCTAAACTCTCTTCAGAGAAAAAACTGCTTGAAGAGACAAAT AAAAAATGGTGTGTTTTGGAAGGAGGCTTCTTGAGTTACTATGAAAATGATAAGTCTACC ACACCTAATGGCACCATTAATATCAATGAAGTTATCTGCCTGGCTATACACAAAGAGGAC TTCTATTTAAATACTGGGCCCATCTTTATCTTTGAGATCTACTTACCCTCCGAACGTGTG TTTTTATTTGGAGCTGAAACATCTCAAGCTCAAAGAAAATGGACAGAGGCAATAGCCAAG CATTTTGTTCCCTTATTTGCTGAAAACTTAACAGAAGCTGACTATGATTTGATTGGTCAA CTCTTCTACAAAGACTGCCATGCCCTGGATCAGTGGAGAAAAGGCTGGTTTGCTATGGAC AAATCCAGCTTGCATTTTTGCCTTCAAATGCAAGAAGTTCAGGGAGATAGAATGCACTTA AGAAGACTGCAAGAGCTAACAATCAGCACAATGGTTCAAAATGGGGAAAAACTGGATGTT TTACTCTTGGTAGAAAAAGGGAGAACATTATACATCCATGGGCATACCAAGTTGGATTTC ACAGTCTGGCATACTGCAATTGAAAAAGCAGCAGGTACAGATGGTAATGCTTTACAAGAT CAGCAGCTCAGCAAAAATGACGTTCCCATTATAGTGAACAGCTGTATAGCATTTGTTACA CAGTATGGTTTAGGATGCAAATATATCTATCAAAAGAATGGTGATCCTTTGCATATAAGT GAACTCCTGGAGAGTTTCAAAAAGGATGCAAGAAGCTTTAAATTGAGGGCTGGAAAACAT CAGCTTGAAGATGTGACGGCTGTGTTGAAAAGTTTTCTCTCTGACATTGATGATGCACTG CTTACTAAGGAGCTCTACCCATATTGGATCTCTGCTTTAGATACGCAAGATGACAAGGAA AGAATTAAAAAATATGGAGCATTTATACGTTCTCTTCCAGGGGTCAACCGAGCAACACTA GCAGCTATCATTGAACACCTGTATAGGGTTCAGAAATGCTCAGAAATCAATCACATGAAT GCCCATAATTTGGCCTTGGTCTTTTCATCCTGTTTGTTTCAAACGAAGGGACAAACTAGT GAAGAAGTGAATGTAATTGAGGACCTAATTAATAATTATGTAGAAATATTTGAGGTTAAA GAAGATCAAGTCAAACAAATGGACATAGAAAATAGCTTTATTACCAAGTGGAAAGACACC CAAGTTTCCCAGGCTGGAGATTTGTTAATTGAAGTATATGTAGAAAGGAAGGAACCCGAC TGTAGTATTATAATTCGGATATCTCCTGTGATGGAAGCAGAAGAATTAACTAATGATATA TTAGCGATAAAAAATATTATTCCTACAAAAGGTGATATTTGGGCCACATTTGAAGTCATT GAAAATGAAGAGCTAGAGCGTCCTCTTCACTACAAGGAAAATGTACTGGAGCAGGTGCTT CGGTGGAGTTCATTAGCTGAACCTGGCTCTGCTTACCTGGTGGTGAAGAGATTCTTAACC GCTGACACAATTAAACACTGCAGTGACCGGAGTACACTGGGAAGCATCAAAGAAGGAATC TTGAAAATCAAAGAAGAACCATCCAAAATACTATCTGGAAATAAGTTTCAAGACCGGTAT TTTGTTTTACGAGATGGGTTTCTCTTTCTTTACAAGGATGTGAAGAGTAGTAAACATGAC AAGATGTTTTCTCTCAGTTCCATGAAGTTTTATCGTGGAGTGAAAAAGAAAATGAAGCCT CCAACAAGCTGGGGATTGACCGCATATTCTGAGAAACATCACTGGCACCTGTGTTGTGAT AGTTCACAAACTCAGACGGAGTGGATGACCAGTATCTTTATTGCCCAGCATGAATATGAT ATATGGCCACCAGCTGGAAAGGAACGAAAACGTTCAATAACCAAAAATCCCAAAATTGGA GGTTTGCCTCTGATTCCTATACAGCATGAGGGGAATGCAACCTTGGCCCGGAAAAATATT GAGAGTGCAAGAGCAGAACTTGAAAGGCTGCGGCTCAGTGAAAAGTGTGATAAAGAGTCC GTGGACTCTAGCTTAAAGGAGAGAGCTTCCATGGTGGCCCACTGCCTGGAGCACAAGGAC GATAAACTTCGAAATCGACCCCGAAAACATCGGAGTTTCAACTGCCTGGAGGACACAGAG CCTGAAGCCCCACTTGGGCAACCAAAAGGCCATAAAGGCCTAAAGACATTGAGGAAGACT GAGGACAGGAATAGCAAAGCTACTTTGGACTCTGATCATAAGTTACCATCAAGGGTAATT GAAGAACTTAATGTGGTTCTACAACGGTCAAGAACCCTTCCAAAAGAATTACAGGATGAG CAGATTTTGAAG
Cloned ORF protein sequence for pFN21AA0580 Download>KIAA0580 1704 aa MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP PTSWGLTAYSEKHHWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI EELNVVLQRSRTLPKELQDEQILK
Nucleotide Sequence (with vector) for pFN21AA0580 Download>pFN21AA0580 9817 bp TCAATATTGGCCATTAGCCATATTATTCATTGGTTATATAGCATAAATCAATATTGGCTA TTGGCCATTGCATACGTTGTATCTATATCATAATATGTACATTTATATTGGCTCATGTCC AATATGACCGCCATGTTGGCATTGATTATTGACTAGTTATTAATAGTAATCAATTACGGG GTCATTAGTTCATAGCCCATATATGGAGTTCCGCGTTACATAACTTACGGTAAATGGCCC GCCTGGCTGACCGCCCAACGACCCCCGCCCATTGACGTCAATAATGACGTATGTTCCCAT AGTAACGCCAATAGGGACTTTCCATTGACGTCAATGGGTGGAGTATTTACGGTAAACTGC CCACTTGGCAGTACATCAAGTGTATCATATGCCAAGTCCGCCCCCTATTGACGTCAATGA CGGTAAATGGCCCGCCTGGCATTATGCCCAGTACATGACCTTACGGGACTTTCCTACTTG GCAGTACATCTACGTATTAGTCATCGCTATTACCATGGTGATGCGGTTTTGGCAGTACAC CAATGGGCGTGGATAGCGGTTTGACTCACGGGGATTTCCAAGTCTCCACCCCATTGACGT CAATGGGAGTTTGTTTTGGCACCAAAATCAACGGGACTTTCCAAAATGTCGTAATAACCC CGCCCCGTTGACGCAAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGC TGGTTTAGTGAACCGTCAGATCACTAGAAGCTTTATTGCGGTAGTTTATCACAGTTAAAT TGCTAACGCAGTCAGTGCTTCTGACACAACAGTCTCGAACTTAAGCTGCAGAAGTTGGTC GTGAGGCACTGGGCAGGTAAGTATCAAGGTTACAAGACAGGTTTAAGGAGACCAATAGAA ACTGGGCTTGTCGAGACAGAGAAGACTCTTGCGTTTCTGATAGGCACCTATTGGTCTTAC TGACATCCACTTTGCCTTTCTCTCCACAGGTGTCCACTCCCAGTTCAATTACAGCTCTTA AGGCTAGAGTATTAATACGACTCACTATAGGGCTAGCAAAGCCACCATGGCAGAAATCGG TACTGGCTTTCCATTCGACCCCCATTATGTGGAAGTCCTGGGCGAGCGCATGCACTACGT CGATGTTGGTCCGCGCGATGGCACCCCTGTGCTGTTCCTGCACGGTAACCCGACCTCCTC CTACGTGTGGCGCAACATCATCCCGCATGTTGCACCGACCCATCGCTGCATTGCTCCAGA CCTGATCGGTATGGGCAAATCCGACAAACCAGACCTGGGTTATTTCTTCGACGACCACGT CCGCTTCATGGATGCCTTCATCGAAGCCCTGGGTCTGGAAGAGGTCGTCCTGGTCATTCA CGACTGGGGCTCCGCTCTGGGTTTCCACTGGGCCAAGCGCAATCCAGAGCGCGTCAAAGG TATTGCATTTATGGAGTTCATCCGCCCTATCCCGACCTGGGACGAATGGCCAGAATTTGC CCGCGAGACCTTCCAGGCCTTCCGCACCACCGACGTCGGCCGCAAGCTGATCATCGATCA GAACGTTTTTATCGAGGGTACGCTGCCGATGGGTGTCGTCCGCCCGCTGACTGAAGTCGA GATGGACCATTACCGCGAGCCGTTCCTGAATCCTGTTGACCGCGAGCCACTGTGGCGCTT CCCAAACGAGCTGCCAATCGCCGGTGAGCCAGCGAACATCGTCGCGCTGGTCGAAGAATA CATGGACTGGCTGCACCAGTCCCCTGTCCCGAAGCTGCTGTTCTGGGGCACCCCAGGCGT TCTGATCCCACCGGCCGAAGCCGCTCGCCTGGCCAAAAGCCTGCCTAACTGCAAGGCTGT GGACATCGGCCCGGGTCTGAATCTGCTGCAAGAAGACAACCCGGACCTGATCGGCAGCGA GATCGCGCGCTGGCTGTCGACGCTCGAGATTTCCGGCGAGCCAACCACTGAGGATCTGTA CTTTCAGAGCGATAACGCGATCGCCATGTCCTCAGTCAGTGAAGTAAATGTGGATATAAA AGATTTCCTAATGAGCATTAATTTGGAGCAGTATCTCTTACATTTCCATGAGTCTGGTTT TACTACTGTGAAGGACTGTGCAGCAATAAATGACAGCCTGCTGCAGAAAATTGGAATATC ACCTACAGGTCACCGTAGGAGGATACTTAAACAGTTACAGATAATCTTGTCAAAAATGCA AGATATTCCAATATATGCAAATGTTCATAAAACTAAGAAGAATGATGACCCTTCAAAGGA TTACCATGTTCCATCTTCTGATCAGAATATCTGCATAGAACTTTCCAATTCTGGTAGTGT TCAGACATCTAGCCCACCGCAGTTGGAGACTGTTAGAAAAAATCTTGAAGACAGTGATGC AAGTGTGGAAAGAAGCCAGTATCCTCAATCAGATGATAAGCTGTCTCCTCCTAAACGCGA CTTCCCCACTGCAGAGGAACCACACCTGAATTTGGGTTCTTTGAATGATTCTTTATTTGG TAGTGACAATATTAAAATAGAATCATTGATTACAAAGAAGACTGTGGATCACACAGTTGA AGAACAACAAACAGAAAAAGTTAAATTGATCACAGAAAATCTCAGTAAGCTCCCTAATGC AGACTCTGAATGCCTTTCTTTTGTTGGCTGTTCAACATCAGGAACAAATTCTGGAAATGG AACAAATGGTTTATTAGAAGGATCACCACCATCCCCATTCTTTAAGTTTCAAGGAGAAAT GATTGTAAATGACTTGTATGTTCCATCATCACCAATCCTAGCACCTGTGAGAAGTCGTAG CAAGTTGGTTTCAAGACCATCTCGATCTTTTCTGCTAAGACATCGACCTGTACCAGAGAT TCCAGGGTCAACAAAAGGAGTTTCTGGGAGCTATTTCCGTGAAAGAAGAAATGTTGCTAC CTCAACTGAAAAATCTGTGGCATGGCAAAATTCAAATGAGGAGAATTCATCTTCCATCTT TCCTTATGGAGAGACCTTTCTCTTCCAGAGACTAGAAAATTCCAAGAAGCGATCTATAAA GAATGAATTTTTGACCCAGGGAGAAGCACTCAAAGGGGAAGCAGCTACTGCAACAAACTC TTTTATCATCAAATCAAGCATATACGATAACAGAAAGGAGAAAATAAGCGAGGACAAGGT GGAAGATATTTGGATACCTCGAGAGGACAAAAACAATTTTTTGATAGACACTGCTTCTGA ATCAGAATACTCAACAGTAGAAGAATGCTTTCAGAGTTTAAGAAGAAAAAATTCAAAGGC ATCTAAATCTAGGACTCAAAAAGCCTTGATTTTGGACTCCGTTAATAGGCACAGTTATCC GTTAAGCTCAACAAGTGGAAATGCTGATTCATCAGCCGTTTCTTCACAGGCAATATCTCC CTATGCCTGCTTTTATGGAGCATCTGCAAAGAAGGTTAAATCAGGATGGCTGGATAAACT CTCTCCTCAAGGAAAACGCATGTTTCAAAAGAGATGGGTGAAATTTGATGGCCTTAGCAT TTCTTACTACAATAATGAGAAGGAGATGTATTCGAAAGGAATAATTCCCCTTTCTGCTAT ATCAACAGTACGAGTTCAAGGAGACAACAAATTTGAAGTTGTTACAACACAAAGAACTTT TGTTTTTAGAGTAGAAAAAGAAGAGGAGAGAAATGACTGGATCAGCATACTATTAAATGC ACTGAAATCACAATCCCTTACCTCGCAGTCTCAAGCTGTTGTTACACCTGAGAAATGTGG ATATCTTGAATTGAGAGGCTATAAGGCAAAAATTTTTACTGTGTTAAGTGGAAACAGTGT GTGGCTTTGCAAAAACGAACAGGATTTTAAGAGTGGACTTGGTATTACCATAATTCCTAT GAATGTAGCAAATGTAAAGCAAGTGGACCGAACTGTGAAACAATCTTTTGAAATAATCAC TCCCTACAGGAGTTTCAGCTTTACAGCCGAGACTGAAAAGGAGAAACAAGACTGGATTGA AGCTGTGCAGCAATCAATAGCAGAAACTCTCTCTGATTATGAAGTAGCTGAGAAGATTTG GTTCAATGAATCCAACAGGAGCTGTGCAGATTGTAAAGCCCCAGATCCTGACTGGGCATC CATCAATCTCTGTGTTGTCATCTGTAAGAAGTGTGCAGGACAGCATAGATCTTTAGGACC AAAAGATTCCAAGGTTAGAAGTCTAAAAATGGATGCTAGCATTTGGAGCAATGAACTCAT CGAGCTTTTTATTGTCATTGGAAACAAAAGAGCAAATGACTTTTGGGCTGGTAATCTTCA AAAGGATGAAGAATTACATATGGACTCACCAGTAGAAAAGAGAAAAAACTTTATTACTCA GAAATATAAAGAAGGAAAATTCAGAAAAACTCTTTTGGCATCTCTCACCAAAGAAGAATT AAATAAGGCTCTATGTGCTGCTGTAGTGAAACCGGATGTTCTAGAAACAATGGCTTTGCT GTTCAGTGGAGCAGATGTCATGTGTGCCACCGGAGACCCCGTGCATAGCACCCCCTATCT GCTAGCCAAGAAAGCTGGGCAAAGTCTGCAAATGGAATTTCTCTACCATAACAAATTCTC AGATTTCCCTCAACATGATATTCATTCCGAGGGTGTATTAAGTCAAGAGTCTTCCCAGTC CACATTCCTCTGTGACTTTTTATATCAAGCTCCTTCTGCTGCTTCTAAACTCTCTTCAGA GAAAAAACTGCTTGAAGAGACAAATAAAAAATGGTGTGTTTTGGAAGGAGGCTTCTTGAG TTACTATGAAAATGATAAGTCTACCACACCTAATGGCACCATTAATATCAATGAAGTTAT CTGCCTGGCTATACACAAAGAGGACTTCTATTTAAATACTGGGCCCATCTTTATCTTTGA GATCTACTTACCCTCCGAACGTGTGTTTTTATTTGGAGCTGAAACATCTCAAGCTCAAAG AAAATGGACAGAGGCAATAGCCAAGCATTTTGTTCCCTTATTTGCTGAAAACTTAACAGA AGCTGACTATGATTTGATTGGTCAACTCTTCTACAAAGACTGCCATGCCCTGGATCAGTG GAGAAAAGGCTGGTTTGCTATGGACAAATCCAGCTTGCATTTTTGCCTTCAAATGCAAGA AGTTCAGGGAGATAGAATGCACTTAAGAAGACTGCAAGAGCTAACAATCAGCACAATGGT TCAAAATGGGGAAAAACTGGATGTTTTACTCTTGGTAGAAAAAGGGAGAACATTATACAT CCATGGGCATACCAAGTTGGATTTCACAGTCTGGCATACTGCAATTGAAAAAGCAGCAGG TACAGATGGTAATGCTTTACAAGATCAGCAGCTCAGCAAAAATGACGTTCCCATTATAGT GAACAGCTGTATAGCATTTGTTACACAGTATGGTTTAGGATGCAAATATATCTATCAAAA GAATGGTGATCCTTTGCATATAAGTGAACTCCTGGAGAGTTTCAAAAAGGATGCAAGAAG CTTTAAATTGAGGGCTGGAAAACATCAGCTTGAAGATGTGACGGCTGTGTTGAAAAGTTT TCTCTCTGACATTGATGATGCACTGCTTACTAAGGAGCTCTACCCATATTGGATCTCTGC TTTAGATACGCAAGATGACAAGGAAAGAATTAAAAAATATGGAGCATTTATACGTTCTCT TCCAGGGGTCAACCGAGCAACACTAGCAGCTATCATTGAACACCTGTATAGGGTTCAGAA ATGCTCAGAAATCAATCACATGAATGCCCATAATTTGGCCTTGGTCTTTTCATCCTGTTT GTTTCAAACGAAGGGACAAACTAGTGAAGAAGTGAATGTAATTGAGGACCTAATTAATAA TTATGTAGAAATATTTGAGGTTAAAGAAGATCAAGTCAAACAAATGGACATAGAAAATAG CTTTATTACCAAGTGGAAAGACACCCAAGTTTCCCAGGCTGGAGATTTGTTAATTGAAGT ATATGTAGAAAGGAAGGAACCCGACTGTAGTATTATAATTCGGATATCTCCTGTGATGGA AGCAGAAGAATTAACTAATGATATATTAGCGATAAAAAATATTATTCCTACAAAAGGTGA TATTTGGGCCACATTTGAAGTCATTGAAAATGAAGAGCTAGAGCGTCCTCTTCACTACAA GGAAAATGTACTGGAGCAGGTGCTTCGGTGGAGTTCATTAGCTGAACCTGGCTCTGCTTA CCTGGTGGTGAAGAGATTCTTAACCGCTGACACAATTAAACACTGCAGTGACCGGAGTAC ACTGGGAAGCATCAAAGAAGGAATCTTGAAAATCAAAGAAGAACCATCCAAAATACTATC TGGAAATAAGTTTCAAGACCGGTATTTTGTTTTACGAGATGGGTTTCTCTTTCTTTACAA GGATGTGAAGAGTAGTAAACATGACAAGATGTTTTCTCTCAGTTCCATGAAGTTTTATCG TGGAGTGAAAAAGAAAATGAAGCCTCCAACAAGCTGGGGATTGACCGCATATTCTGAGAA ACATCACTGGCACCTGTGTTGTGATAGTTCACAAACTCAGACGGAGTGGATGACCAGTAT CTTTATTGCCCAGCATGAATATGATATATGGCCACCAGCTGGAAAGGAACGAAAACGTTC AATAACCAAAAATCCCAAAATTGGAGGTTTGCCTCTGATTCCTATACAGCATGAGGGGAA TGCAACCTTGGCCCGGAAAAATATTGAGAGTGCAAGAGCAGAACTTGAAAGGCTGCGGCT CAGTGAAAAGTGTGATAAAGAGTCCGTGGACTCTAGCTTAAAGGAGAGAGCTTCCATGGT GGCCCACTGCCTGGAGCACAAGGACGATAAACTTCGAAATCGACCCCGAAAACATCGGAG TTTCAACTGCCTGGAGGACACAGAGCCTGAAGCCCCACTTGGGCAACCAAAAGGCCATAA AGGCCTAAAGACATTGAGGAAGACTGAGGACAGGAATAGCAAAGCTACTTTGGACTCTGA TCATAAGTTACCATCAAGGGTAATTGAAGAACTTAATGTGGTTCTACAACGGTCAAGAAC CCTTCCAAAAGAATTACAGGATGAGCAGATTTTGAAGGTTTAAACGAATTCGGGCTCGGT ACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGATCCGGCTGCTAACAAAG CCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATAACTAGCATAACCCCTTG GGGCGGCCGCTTCGAGCAGACATGATAAGATACATTGATGAGTTTGGACAAACCACAACT AGAATGCAGTGAAAAAAATGCTTTATTTGTGAAATTTGTGATGCTATTGCTTTATTTGTA ACCATTATAAGCTGCAATAAACAAGTTAACAACAACAATTGCATTCATTTTATGTTTCAG GTTCAGGGGGAGATGTGGGAGGTTTTTTTAAGCAAGTAAAACCTCTACAAATGTGGTAAA ATCGAATTCTAATGGATCCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCAGTAG CTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTAATGGTTTCT TAGACGTCAGGTGGCACTTTTCGGGGAAATGTGCGCGGAACCCCTATTTGTTTATTTTTC TAAATACATTCAAATATGTATCCGCTCATGAGACAATAACCCTGATAAATGCTTCAATAA TATTGAAAAAGGAAGAGTATGAGTATTCAACATTTCCGTGTCGCCCTTATTCCCTTTTTT GCGGCATTTTGCCTTCCTGTTTTTGCTCACCCAGAAACGCTGGTGAAAGTAAAAGATGCT GAAGATCAGTTGGGTGCACGAGTGGGTTACATCGAACTGGATCTCAACAGCGGTAAGATC CTTGAGAGTTTTCGCCCCGAAGAACGTTTTCCAATGATGAGCACTTTCAAAGTTCTGCTA TGTGGCGCGGTATTATCCCGTATTGACGCCGGGCAAGAGCAACTCGGTCGCCGCATACAC TATTCTCAGAATGACTTGGTTGAGTACTCACCAGTCACAGAAAAGCATCTTACGGATGGC ATGACAGTAAGAGAATTATGCAGTGCTGCCATAACCATGAGTGATAACACTGCGGCCAAC TTACTTCTGACAACTATCGGAGGACCGAAGGAGCTAACCGCTTTTTTGCACAACATGGGG GATCATGTAACTCGCCTTGATCGTTGGGAACCGGAGCTGAATGAAGCCATACCAAACGAC GAGCGTGACACCACGATGCCTGTAGCAATGGCAACAACGTTGCGCAAACTATTAACTGGC GAACTACTTACTCTAGCTTCCCGGCAACAATTAATAGACTGGATGGAGGCGGATAAAGTT GCAGGACCACTTCTGCGCTCGGCCCTTCCGGCTGGCTGGTTTATTGCTGATAAATCTGGA GCCGGTGAGCGTGGGTCTCGCGGTATCATTGCAGCACTGGGGCCAGATGGTAAGCCCTCC CGTATCGTAGTTATCTACACGACGGGGAGTCAGGCAACTATGGATGAACGAAATAGACAG ATCGCTGAGATAGGTGCCTCACTGATTAAGCATTGGTAATTCGAAATGACCGACCAAGCG ACGCCCAACCGGTATCAGCTCACTCAAAGGCGGTAATACGGTTATCCACAGAATCAGGGG ATAACGCAGGAAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGG CCGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGAC GCTCAAGTCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTG GAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCT TTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGG TGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCT GCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCAC TGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGT TCTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGGACAGTATTTGGTATCTGCGCTC TGCTGAAGCCAGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCA CCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAAAGGAT TTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCAC GTTAAGGGATTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTATAGT CCGGAAATACAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAA TGGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTA TTCATACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCA TTTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAG GGATTATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACT CCGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCT
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