Gene/Protein Characteristic Table for FHC03346

Species
human

Product ID
FHC03346

Corresponding
Flexi Clone PID

ORF Sequence
DNA sequence (1050 bp)
Protein sequence (350 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB464598]

Gene
KIBB9835

Symbol

Description
chemokine (C-X-C motif) receptor 1

Original Clone ID
cp00404

Quality control data of this clone

Characterization of the cloned ORF

N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand

Features of the cloned ORF sequence

Length: 1050 bp
Restriction map A Restriction map B
Features of the protein sequence

Length: 350 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
NP_000625 7.3e-151 100.0 C-X-C chemokine...
Homo sapiens
AAA59159 1.2e-150 99.7 IL-8 receptor [...
Homo sapiens
AAY21519 1.9e-150 99.7 CXCR1 [Homo sap...
Homo sapiens
AAX36779 1.9e-150 99.7 interleukin 8 r...
synthetic construct
AAY21514 2.6e-150 99.7 CXCR1 [Homo sap...
Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PR00572 PR00572 PR00427 PR00237 PR00645 PR00427 PR00237 PR00645 PR00427 PR00237 PR00645 PR00237 PR00572 PR00427 PR00237 PR00427 PR00237 PR00427 PR00645 PR00237 PR00427 PR00572 PR00572 PF00001 PS50262 PS00237

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR001355 3 14 PR00572 Interleukin 8A receptor
IPR001355 24 37 PR00572 Interleukin 8A receptor
IPR000174 26 40 PR00427 Interleukin-8 receptor
IPR000276 41 65 PR00237 Rhodopsin-like GPCR superfamily
IPR001277 64 80 PR00645 C-X-C chemokine receptor
IPR000174 66 77 PR00427 Interleukin-8 receptor
IPR000276 74 95 PR00237 Rhodopsin-like GPCR superfamily
IPR001277 101 116 PR00645 C-X-C chemokine receptor
IPR000174 111 124 PR00427 Interleukin-8 receptor
IPR000276 117 139 PR00237 Rhodopsin-like GPCR superfamily
IPR001277 137 148 PR00645 C-X-C chemokine receptor
IPR000276 152 173 PR00237 Rhodopsin-like GPCR superfamily
IPR001355 171 184 PR00572 Interleukin 8A receptor
IPR000174 195 211 PR00427 Interleukin-8 receptor
IPR000276 203 226 PR00237 Rhodopsin-like GPCR superfamily
IPR000174 223 238 PR00427 Interleukin-8 receptor
IPR000276 240 264 PR00237 Rhodopsin-like GPCR superfamily
IPR000174 265 281 PR00427 Interleukin-8 receptor
IPR001277 273 287 PR00645 C-X-C chemokine receptor
IPR000276 287 313 PR00237 Rhodopsin-like GPCR superfamily
IPR000174 315 331 PR00427 Interleukin-8 receptor
IPR001355 329 339 PR00572 Interleukin 8A receptor
IPR001355 339 349 PR00572 Interleukin 8A receptor
HMMPfam IPR000276 56 305 PF00001 Rhodopsin-like GPCR superfamily
ProfileScan IPR000276 56 305 PS50262 Rhodopsin-like GPCR superfamily
ScanRegExp IPR000276 123 139 PS00237 Rhodopsin-like GPCR superfamily

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 41 VVIIAYALVFLLSLLGNSLVMLV 63 PRIMARY 23
2 75 DVYLLNLALADLLFALTLPIWAA 97 PRIMARY 23
3 113 VSLLKEVNFYSGILLLACISVDR 135 SECONDARY 23
4 153 VKFVCLGCWGLSMNLSLPFFLFR 175 SECONDARY 23
5 200 MVLRILPHTFGFIVPLFVMLFCY 222 PRIMARY 23
6 243 VIFAVVLIFLLCWLPYNLVLLAD 265 PRIMARY 23

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_000625 350 146929,609423 100.0 100.0
NP_001548 360 146928 90.4 97.4
NP_004358 374 601835 75.5 91.1
NP_113597 374 601835 75.5 91.1
NP_001495 368 300574 67.9 93.7
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