Gene/Protein Characteristic Table for FXC01174

Species
human

Product ID
FXC01174

Corresponding
HaloTag Clone PID

ORF Sequence
DNA sequence (3363 bp)
Protein sequence (1121 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB385479]

Gene

Symbol
GPR124
Alias : TEM5

Description
G protein-coupled receptor 124

Original Clone ID

Features of the cloned ORF sequence

Length: 3363 bp
Restriction map A Restriction map B
Genomic Structure
Features of the protein sequence

Length: 1121 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
EAW63357 0 99.9 G protein-coupl...
Homo sapiens
AAI46775 0 100.0 GPR124 protein ...
Homo sapiens
BAB84925 5.1e-208 83.2 FLJ00170 protei...
Homo sapiens
Q96PE1 5.2e-208 83.6 Probable G-prot...
Homo sapiens
EAW63355 5.2e-208 83.7 G protein-coupl...
Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PR00019 PR00019 PF00560 PF00560 PF00560 PF00560 PF02793 SM00369 SM00369 SM00369 SM00369 SM00082 SM00409 PS50835 PS50227 PS50261 PS00650

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR001611 110 123 PR00019 Leucine-rich repeat
IPR001611 131 144 PR00019 Leucine-rich repeat
HMMPfam IPR001611 85 107 PF00560 Leucine-rich repeat
IPR001611 109 131 PF00560 Leucine-rich repeat
IPR001611 133 155 PF00560 Leucine-rich repeat
IPR001611 157 179 PF00560 Leucine-rich repeat
IPR001879 367 421 PF02793 Hormone receptor
HMMSmart IPR003591 82 106 SM00369 Leucine-rich repeat
IPR003591 107 130 SM00369 Leucine-rich repeat
IPR003591 131 154 SM00369 Leucine-rich repeat
IPR003591 155 178 SM00369 Leucine-rich repeat
IPR000483 190 240 SM00082 Cysteine-rich flanking region
IPR003599 253 346 SM00409 Immunoglobulin subtype
ProfileScan IPR007110 260 344 PS50835 Immunoglobulin-like
IPR001879 327 421 PS50227 Hormone receptor
IPR000832 552 727 PS50261 GPCR
ScanRegExp IPR000832 844 859 PS00650 GPCR

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 14 RLLLPLLPWLLLLLAPEARGAPG 36 SECONDARY 23
2 552 LHPVVYPCTALLLLCLFATIITY 574 PRIMARY 23
3 589 HMLLNLCFHIAMTSAVFAGGITL 611 SECONDARY 23
4 666 PMLRFYLIAGGIPLIICGITAAV 688 SECONDARY 23
5 711 FYIPVALILLITWIYFLCAGLR 732 PRIMARY 22
6 799 GVQLGALVTTHFLYLAMWACGAL 821 SECONDARY 23
7 831 VVCSCLYGVAASALGLFVFTHHC 853 PRIMARY 23

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_116166 1331 606823 83.6 99.4
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