HUGE

Gene/Protein Characteristic Table for KIAA1739

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK06763
Accession No. :	AB051526
Description :	Semaphorin-4C precursor.
HUGO Gene Name :
Clone Name :	pj00464 [Vector Info]
Flexi ORF Clone :	pF1KA1739
Source :	Human brain (hippocampus)

Features of the cloned DNA sequence	Description

Length: 3776 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 884 bp

Genome contig ID gi89161199r_96789206
PolyA signal sequence
(AATAAA,-18)
+----*----+----*----+----*----+----
GTATTTTTATATTGACAAATAAAATGGAGAAAATG
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AAACGATTGCTCTGATGGGGCTAAGATGTTTGGGCTAAAGCCTTTCTGGG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 2 r 96889206 96896394 13 99.5 Perfect prediction

Features of the protein sequence	Description

Length: 963 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
EAW71325	100.0	sema domain, im...	Homo sapiens
Q9C0C4	96.8	Semaphorin-4C; ...	Homo sapiens
AAQ89201	96.6	SEMA4C [Homo sa...	Homo sapiens
XP_001100467	94.1	semaphorin 4C [...	Macaca mulatta
XP_515634	84.2	semaphorin 4C [...	Pan troglodytes

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB046839	1.1e-61	41.3	KIAA1619
AB051532	1.3e-54	40.5	KIAA1745
AB002329	1.6e-30	33.6	KIAA0331
AB058772	6.8e-21	35.6	KIAA1869
AB040912	1.7e-19	33.7	KIAA1479

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR001627 183 611 PF01403 Semaphorin/CD100 antigen

IPR002165 629 681 PF01437 Plexin

HMMSmart IPR001627 183 611 SM00630 Semaphorin/CD100 antigen

IPR003659 629 681 SM00423 Plexin/semaphorin/integrin

IPR003599 692 776 SM00409 Immunoglobulin subtype

ProfileScan IPR001627 160 627 PS51004 Semaphorin/CD100 antigen

IPR007110 686 767 PS50835 Immunoglobulin-like

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR001627	183	611	PF01403	Semaphorin/CD100 antigen
IPR002165	629	681	PF01437	Plexin
HMMSmart	IPR001627	183	611	SM00630	Semaphorin/CD100 antigen
IPR003659	629	681	SM00423	Plexin/semaphorin/integrin
IPR003599	692	776	SM00409	Immunoglobulin subtype
ProfileScan	IPR001627	160	627	PS51004	Semaphorin/CD100 antigen
IPR007110	686	767	PS50835	Immunoglobulin-like

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 25 HSRLCLLLCWTLIEAVGSR 43 SECONDARY 19

2 730 PGSFLYDARLQALVVMAA 747 SECONDARY 18

3 765 RLAAEGYLVAVVAGPSVTLEAR 786 SECONDARY 22

4 791 NLGLVWLAVVALGAVCLVLLLLV 813 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	25	HSRLCLLLCWTLIEAVGSR	43	SECONDARY	19
2	730	PGSFLYDARLQALVVMAA	747	SECONDARY	18
3	765	RLAAEGYLVAVVAGPSVTLEAR	786	SECONDARY	22
4	791	NLGLVWLAVVALGAVCLVLLLLV	813	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: ATGCTGGCCTTCTTGTGGATG

Primer_r
: CACACTCTCAGGTACATAGGC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 2

Experimental conditions

Panel name	: unigene
Primer_f	: -
Primer_r	: -
PCR product length	: -
PCR conditions	: -

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	884 bp
Genome contig ID	gi89161199r_96789206
PolyA signal sequence (AATAAA,-18)	+--------+--------+----*----+---- GTATTTTTATATTGACAAATAAAATGGAGAAAATG
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AAACGATTGCTCTGATGGGGCTAAGATGTTTGGGCTAAAGCCTTTCTGGG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	2	r	96889206	96896394	13	99.5	Perfect prediction

Primer_f	: ATGCTGGCCTTCTTGTGGATG
Primer_r	: CACACTCTCAGGTACATAGGC
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA1739

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information