HUGE

Gene/Protein Characteristic Table for KIAA0946

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00155
Accession No. :	AB023163
Description :	Palmitoyltransferase ZDHHC17.
HUGO Gene Name :	zinc finger, DHHC-type containing 17 (ZDHHC17)
Clone Name :	hj04787 [Vector Info]
Flexi ORF Clone :	pF1KA0946
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4715 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 2709 bp

Genome contig ID gi89161190f_75582041
PolyA signal sequence
(AATAAA,-17)
+----*----+----*----+----*----+----
TTGTAAAATATTAATCAGAATAAATACTGACTCTT
Flanking genome sequence
(189566 - 189615)
----+----*----+----*----+----*----+----*----+----*
AAGTGTGTGCTTATGATTTCACTCAATTTACTTCAGGAAATTGATGAAAT

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 12 f 75682041 75771605 17 100.0 Perfect prediction

Features of the protein sequence	Description

Length: 667 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
XP_509231	99.8	huntingtin inte...	Pan troglodytes
XP_001082309	99.7	huntingtin inte...	Macaca mulatta
Q8IUH5	100.0	Palmitoyltransf...	Homo sapiens
XP_614891	99.4	similar to hunt...	Bos taurus
BAC22089	99.7	huntingtin inte...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB051535	1.6e-10	30.6	KIAA1748
AB002377	3.2e-09	29.9	KIAA0379
AB046856	3.7e-09	29.5	KIAA1636
AB033076	5.7e-09	30.1	KIAA1250
AB095935	1.2e-08	27.1	KIAA2015

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

BlastProDom IPR001594 431 504 PD003041 Zinc finger

FPrintScan IPR002110 159 171 PR01415 Ankyrin

IPR002110 272 284 PR01415 Ankyrin

HMMPfam IPR002110 124 156 PF00023 Ankyrin

IPR002110 158 190 PF00023 Ankyrin

IPR002110 191 223 PF00023 Ankyrin

IPR002110 224 257 PF00023 Ankyrin

IPR002110 259 291 PF00023 Ankyrin

IPR001594 468 527 PF01529 Zinc finger

HMMSmart IPR002110 124 153 SM00248 Ankyrin

IPR002110 158 187 SM00248 Ankyrin

IPR002110 191 220 SM00248 Ankyrin

IPR002110 224 254 SM00248 Ankyrin

IPR002110 259 288 SM00248 Ankyrin

ProfileScan IPR002110 99 312 PS50297 Ankyrin

IPR002110 124 156 PS50088 Ankyrin

IPR002110 158 190 PS50088 Ankyrin

IPR002110 191 223 PS50088 Ankyrin

IPR002110 224 257 PS50088 Ankyrin

IPR002110 259 291 PS50088 Ankyrin

IPR001594 472 522 PS50216 Zinc finger

Search method	interpro_ID	From	To	Entry	Definition
BlastProDom	IPR001594	431	504	PD003041	Zinc finger
FPrintScan	IPR002110	159	171	PR01415	Ankyrin
IPR002110	272	284	PR01415	Ankyrin
HMMPfam	IPR002110	124	156	PF00023	Ankyrin
IPR002110	158	190	PF00023	Ankyrin
IPR002110	191	223	PF00023	Ankyrin
IPR002110	224	257	PF00023	Ankyrin
IPR002110	259	291	PF00023	Ankyrin
IPR001594	468	527	PF01529	Zinc finger
HMMSmart	IPR002110	124	153	SM00248	Ankyrin
IPR002110	158	187	SM00248	Ankyrin
IPR002110	191	220	SM00248	Ankyrin
IPR002110	224	254	SM00248	Ankyrin
IPR002110	259	288	SM00248	Ankyrin
ProfileScan	IPR002110	99	312	PS50297	Ankyrin
IPR002110	124	156	PS50088	Ankyrin
IPR002110	158	190	PS50088	Ankyrin
IPR002110	191	223	PS50088	Ankyrin
IPR002110	224	257	PS50088	Ankyrin
IPR002110	259	291	PS50088	Ankyrin
IPR001594	472	522	PS50216	Zinc finger

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 339 KVMLGTPFLVIWLVGFIADLNID 361 PRIMARY 23

2 363 WLIKGLMYGGVWATVQFLSKSFF 385 SECONDARY 23

3 392 ALPLGIYLATKFWMYVTWFFWFW 414 SECONDARY 23

4 417 LNFLFIHLPFLANSVALFYNFGK 439 SECONDARY 23

5 515 RYFMGYLFFLLFMICWMIYGCIS 537 PRIMARY 23

6 571 LNSVFHFMWVAVLLMCQMYQISC 593 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	339	KVMLGTPFLVIWLVGFIADLNID	361	PRIMARY	23
2	363	WLIKGLMYGGVWATVQFLSKSFF	385	SECONDARY	23
3	392	ALPLGIYLATKFWMYVTWFFWFW	414	SECONDARY	23
4	417	LNFLFIHLPFLANSVALFYNFGK	439	SECONDARY	23
5	515	RYFMGYLFFLLFMICWMIYGCIS	537	PRIMARY	23
6	571	LNSVFHFMWVAVLLMCQMYQISC	593	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: AAATGGTCAGATGGTCAGGAG

Primer_r
: CCCAAAGGTTCACCATCATAC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 12

Experimental conditions

Panel name	: UniGene
Primer_f	: -
Primer_r	: -
PCR product length	: -
PCR conditions	: -

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	2709 bp
Genome contig ID	gi89161190f_75582041
PolyA signal sequence (AATAAA,-17)	+--------+--------+----*----+---- TTGTAAAATATTAATCAGAATAAATACTGACTCTT
Flanking genome sequence (189566 - 189615)	----+--------+--------+--------+--------+----* AAGTGTGTGCTTATGATTTCACTCAATTTACTTCAGGAAATTGATGAAAT

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	12	f	75682041	75771605	17	100.0	Perfect prediction

Primer_f	: AAATGGTCAGATGGTCAGGAG
Primer_r	: CCCAAAGGTTCACCATCATAC
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA0946

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information