HUGE

Gene/Protein Characteristic Table for KIAA0821

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00646
Accession No. :	AB020628
Description :	Latrophilin-1 precursor.
HUGO Gene Name :	latrophilin 1 (LPHN1)
Clone Name :	hh02631 [Vector Info]
Flexi ORF Clone :	pF1KSDA0821
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 5659 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 936 bp

Genome contig ID gi42406306r_14021763
PolyA signal sequence
(AAGAAA,-17)
+----*----+----*----+----*----+----
TATTTCAACGAAATGGAAAAGAAAAAAAAAAAGAC
Flanking genome sequence
(99987 - 99938)
----+----*----+----*----+----*----+----*----+----*
AAAAAAAAAAAAAAAGAAAAGAAAAAAAATCTCATCACTTGAAGCCACCG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 19 r 14121750 14178000 23 99.4 Perfect prediction

Features of the protein sequence	Description

Length: 1566 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
O94910	100.0	Latrophilin-1; ...	Homo sapiens
AAG27461	99.6	lectomedin-2 [H...	Homo sapiens
EAW84408	99.1	latrophilin 1, ...	Homo sapiens
XP_867067	98.8	similar to latr...	Canis lupus fam...
XP_001789501	98.6	latrophilin 1 i...	Bos taurus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB018329	6e-107	63.2	KIAA0786
AB018311	3.3e-59	48.1	KIAA0768
D87469	4.6e-15	27.1	KIAA0279
AB011536	5.3e-14	24.1	KIAA0812
AB011122	2.7e-10	25.6	KIAA0550

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

BlastProDom IPR000922 127 220 PD005612 D-galactoside/L-rhamnose binding SUEL lectin

FPrintScan IPR003924 153 164 PR01444 Latrophilin receptor

IPR003924 175 194 PR01444 Latrophilin receptor

IPR003924 203 223 PR01444 Latrophilin receptor

IPR003924 316 338 PR01444 Latrophilin receptor

IPR003924 359 374 PR01444 Latrophilin receptor

IPR000832 954 978 PR00249 GPCR

IPR003924 979 994 PR01444 Latrophilin receptor

IPR000832 1017 1040 PR00249 GPCR

IPR000832 1097 1122 PR00249 GPCR

IPR000832 1171 1192 PR00249 GPCR

IPR003924 1193 1205 PR01444 Latrophilin receptor

HMMPfam IPR000922 140 220 PF02140 D-galactoside/L-rhamnose binding SUEL lectin

IPR003112 234 490 PF02191 Olfactomedin-like

IPR001879 569 629 PF02793 Hormone receptor

IPR000203 890 937 PF01825 GPS

IPR000832 949 1196 PF00002 GPCR

IPR003334 1206 1566 PF02354 Latrophilin

HMMSmart IPR003112 234 490 SM00284 Olfactomedin-like

IPR001879 568 633 SM00008 Hormone receptor

IPR000203 890 942 SM00303 GPS

ProfileScan IPR000922 132 221 PS50228 D-galactoside/L-rhamnose binding SUEL lectin

IPR003112 231 490 PS51132 Olfactomedin-like

IPR001879 569 628 PS50227 Hormone receptor

IPR000203 891 942 PS50221 GPS

IPR000832 952 1193 PS50261 GPCR

ScanRegExp IPR000832 1181 1196 PS00650 GPCR

Search method	interpro_ID	From	To	Entry	Definition
BlastProDom	IPR000922	127	220	PD005612	D-galactoside/L-rhamnose binding SUEL lectin
FPrintScan	IPR003924	153	164	PR01444	Latrophilin receptor
IPR003924	175	194	PR01444	Latrophilin receptor
IPR003924	203	223	PR01444	Latrophilin receptor
IPR003924	316	338	PR01444	Latrophilin receptor
IPR003924	359	374	PR01444	Latrophilin receptor
IPR000832	954	978	PR00249	GPCR
IPR003924	979	994	PR01444	Latrophilin receptor
IPR000832	1017	1040	PR00249	GPCR
IPR000832	1097	1122	PR00249	GPCR
IPR000832	1171	1192	PR00249	GPCR
IPR003924	1193	1205	PR01444	Latrophilin receptor
HMMPfam	IPR000922	140	220	PF02140	D-galactoside/L-rhamnose binding SUEL lectin
IPR003112	234	490	PF02191	Olfactomedin-like
IPR001879	569	629	PF02793	Hormone receptor
IPR000203	890	937	PF01825	GPS
IPR000832	949	1196	PF00002	GPCR
IPR003334	1206	1566	PF02354	Latrophilin
HMMSmart	IPR003112	234	490	SM00284	Olfactomedin-like
IPR001879	568	633	SM00008	Hormone receptor
IPR000203	890	942	SM00303	GPS
ProfileScan	IPR000922	132	221	PS50228	D-galactoside/L-rhamnose binding SUEL lectin
IPR003112	231	490	PS51132	Olfactomedin-like
IPR001879	569	628	PS50227	Hormone receptor
IPR000203	891	942	PS50221	GPS
IPR000832	952	1193	PS50261	GPCR
ScanRegExp	IPR000832	1181	1196	PS00650	GPCR

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 92 TMARLAAVLWNLCVTAVLVTSAT 114 PRIMARY 23

2 953 SVITWVGIVISLVCLAICISTFC 975 PRIMARY 23

3 986 TIHKNLCINLFLAELLFLVGID 1007 SECONDARY 22

4 1021 LLHYFFLAAFSWLCLEGVHLYLL 1043 PRIMARY 23

5 1059 YLGGYCFPALVVGIAAAIDYR 1079 PRIMARY 21

6 1097 WSFIGPVSFVIVVNLVFLMVTLH 1119 PRIMARY 23

7 1139 KSWALGAIALLFLLGLTWAFGLL 1161 PRIMARY 23

8 1170 MAYLFTTFNAFQGVFIFVFHCAL 1192 SECONDARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	92	TMARLAAVLWNLCVTAVLVTSAT	114	PRIMARY	23
2	953	SVITWVGIVISLVCLAICISTFC	975	PRIMARY	23
3	986	TIHKNLCINLFLAELLFLVGID	1007	SECONDARY	22
4	1021	LLHYFFLAAFSWLCLEGVHLYLL	1043	PRIMARY	23
5	1059	YLGGYCFPALVVGIAAAIDYR	1079	PRIMARY	21
6	1097	WSFIGPVSFVIVVNLVFLMVTLH	1119	PRIMARY	23
7	1139	KSWALGAIALLFLLGLTWAFGLL	1161	PRIMARY	23
8	1170	MAYLFTTFNAFQGVFIFVFHCAL	1192	SECONDARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: TCCTGATGAAGCACAACTCCC

Primer_r
: TTTACAGCAATGGGGAAGGAG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 19

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: TCCTGATGAAGCACAACTCCC
Primer_r	: TTTACAGCAATGGGGAAGGAG
PCR product length	: 203 bp
PCR conditions	: 95 °C15 sec64 °C60 sec35 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	936 bp
Genome contig ID	gi42406306r_14021763
PolyA signal sequence (AAGAAA,-17)	+--------+--------+----*----+---- TATTTCAACGAAATGGAAAAGAAAAAAAAAAAGAC
Flanking genome sequence (99987 - 99938)	----+--------+--------+--------+--------+----* AAAAAAAAAAAAAAAGAAAAGAAAAAAAATCTCATCACTTGAAGCCACCG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	19	r	14121750	14178000	23	99.4	Perfect prediction

Gene/Protein Characteristic Table for KIAA0821

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information