HUGE

Gene/Protein Characteristic Table for KIAA0812

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Mapping

Product ID :	ORK06860
Accession No. :	AB011536
Description :	Solute carrier family 26 member 6.
HUGO Gene Name :
Clone Name :	hg01044 [Vector Info]
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 5832 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 1736 bp

Genome contig ID gi89161205r_48548906
PolyA signal sequence
(AATAAA,-15)
+----*----+----*----+----*----+----
AAGCCGCGCTCTGTTTTGGGAATAAACTTCTATAG
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AAAACAGTTGTTGCCTTTTCCTGTTGGGGGCTGGGGAGGTAGGATGGAAG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 3 r 48648906 48664378 24 99.9 Perfect prediction

Features of the protein sequence	Description

Length: 1364 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
BAA32464	100.0	MEGF2 [Homo sap...	Homo sapiens
EAW64914	99.6	cadherin, EGF L...	Homo sapiens
Q9NYQ7	99.6	Cadherin EGF LA...	Homo sapiens
NP_001398	99.6	cadherin EGF LA...	Homo sapiens
O88278	93.4	Cadherin EGF LA...	Rattus norvegicus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
D87469	6.5e-42	43.5	KIAA0279
AB020628	2.4e-16	24.2	KIAA0821
AB018329	3.1e-15	26.2	KIAA0786
AB018311	4.5e-15	29.8	KIAA0768
AB011122	1.4e-09	22.0	KIAA0550

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR000832 593 617 PR00249 GPCR

IPR000832 656 679 PR00249 GPCR

IPR000832 694 719 PR00249 GPCR

IPR000832 736 761 PR00249 GPCR

IPR000832 805 826 PR00249 GPCR

HMMPfam IPR006209 2 28 PF00008 EGF-like

IPR006209 32 66 PF00008 EGF-like

IPR002049 124 157 PF00053 EGF-like

IPR001879 173 235 PF02793 Hormone receptor

IPR000203 528 576 PF01825 GPS

IPR000832 588 830 PF00002 GPCR

HMMSmart IPR006210 1 29 SM00181 EGF

IPR006210 31 67 SM00181 EGF

IPR002049 124 169 SM00180 EGF-like

IPR001879 172 239 SM00008 Hormone receptor

IPR000203 528 581 SM00303 GPS

ProfileScan IPR000742 1 26 PS50026 EGF-like

IPR000742 29 67 PS50026 EGF-like

IPR002049 124 171 PS50027 EGF-like

IPR001879 156 234 PS50227 Hormone receptor

IPR000203 529 581 PS50221 GPS

IPR000832 591 827 PS50261 GPCR

ScanRegExp IPR000152 8 19 PS00010 Aspartic acid and asparagine hydroxylation site

IPR013032 17 28 PS00022 EGF-like region

IPR013032 17 32 PS01186 EGF-like region

IPR013032 55 66 PS00022 EGF-like region

IPR013032 55 66 PS01186 EGF-like region

IPR013032 143 154 PS00022 EGF-like region

IPR002049 143 176 PS01248 EGF-like

IPR000832 815 830 PS00650 GPCR

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR000832	593	617	PR00249	GPCR
IPR000832	656	679	PR00249	GPCR
IPR000832	694	719	PR00249	GPCR
IPR000832	736	761	PR00249	GPCR
IPR000832	805	826	PR00249	GPCR
HMMPfam	IPR006209	2	28	PF00008	EGF-like
IPR006209	32	66	PF00008	EGF-like
IPR002049	124	157	PF00053	EGF-like
IPR001879	173	235	PF02793	Hormone receptor
IPR000203	528	576	PF01825	GPS
IPR000832	588	830	PF00002	GPCR
HMMSmart	IPR006210	1	29	SM00181	EGF
IPR006210	31	67	SM00181	EGF
IPR002049	124	169	SM00180	EGF-like
IPR001879	172	239	SM00008	Hormone receptor
IPR000203	528	581	SM00303	GPS
ProfileScan	IPR000742	1	26	PS50026	EGF-like
IPR000742	29	67	PS50026	EGF-like
IPR002049	124	171	PS50027	EGF-like
IPR001879	156	234	PS50227	Hormone receptor
IPR000203	529	581	PS50221	GPS
IPR000832	591	827	PS50261	GPCR
ScanRegExp	IPR000152	8	19	PS00010	Aspartic acid and asparagine hydroxylation site
IPR013032	17	28	PS00022	EGF-like region
IPR013032	17	32	PS01186	EGF-like region
IPR013032	55	66	PS00022	EGF-like region
IPR013032	55	66	PS01186	EGF-like region
IPR013032	143	154	PS00022	EGF-like region
IPR002049	143	176	PS01248	EGF-like
IPR000832	815	830	PS00650	GPCR

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 592 AVFTHVVVAVSVAALVLTAAILL 614 PRIMARY 23

2 625 GIHANVAAALGVAELLFLLGIHR 647 SECONDARY 23

3 656 AVAILLHYFFLSTFAWLFVQGLH 678 PRIMARY 23

4 694 MRFYHALGWGVPAVLLGLAVGL 715 PRIMARY 22

5 738 FAGPVVLVIVMNGTMFLLAART 759 PRIMARY 22

6 776 LRSSFLLLLLVSASWLFGLLAVN 798 PRIMARY 23

7 808 HAGLCGLQGLAVLLLFCVLNAD 829 PRIMARY 22

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	592	AVFTHVVVAVSVAALVLTAAILL	614	PRIMARY	23
2	625	GIHANVAAALGVAELLFLLGIHR	647	SECONDARY	23
3	656	AVAILLHYFFLSTFAWLFVQGLH	678	PRIMARY	23
4	694	MRFYHALGWGVPAVLLGLAVGL	715	PRIMARY	22
5	738	FAGPVVLVIVMNGTMFLLAART	759	PRIMARY	22
6	776	LRSSFLLLLLVSASWLFGLLAVN	798	PRIMARY	23
7	808	HAGLCGLQGLAVLLLFCVLNAD	829	PRIMARY	22

RH mapping information	Description

Chromosome No.

: 3

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: TCGGTAAGGAGAGTTTGGGTC
Primer_r	: CAGACACTCCTCACCCACCAC
PCR product length	: 124 bp
PCR conditions	: 95 °C15 sec66 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	1736 bp
Genome contig ID	gi89161205r_48548906
PolyA signal sequence (AATAAA,-15)	+--------+--------+----*----+---- AAGCCGCGCTCTGTTTTGGGAATAAACTTCTATAG
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AAAACAGTTGTTGCCTTTTCCTGTTGGGGGCTGGGGAGGTAGGATGGAAG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	3	r	48648906	48664378	24	99.9	Perfect prediction

Gene/Protein Characteristic Table for KIAA0812

Features of the cloned DNA sequence

Features of the protein sequence

RH mapping information