HUGE

Gene/Protein Characteristic Table for KIAA0271

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00485
Accession No. :	D87461
Description :	Apoptosis regulator Bcl-W.
HUGO Gene Name :	BCL2-like 2 (BCL2L2)
Clone Name :	ha06752 [Vector Info]
Flexi ORF Clone :	pF1KSDA0271
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 3542 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 2784 bp

Genome contig ID gi51511730f_22745876
PolyA signal sequence
(AATAAA,-24)
+----*----+----*----+----*----+----
TAAAAACAATAAATAAAGCCCAGAAGTTTAATGAG
Flanking genome sequence
(104924 - 104973)
----+----*----+----*----+----*----+----*----+----*
AAGGACTGAACAGGGTTTGTGACTTCTACACTGTATAGCCTGGGGTCAGG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 14 f 22845876 22850798 4 99.0 Terminal No-hit

Features of the protein sequence	Description

Length: 202 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
ABJ16412	2e-80	100.0	BCL2L2 [Felis c...	Felis catus
AAO64470	1.8e-79	98.5	BCL-WEL [Rattus...	Rattus norvegicus
Q92843	2.6e-79	100.0	Apoptosis regul...	Homo sapiens
AAX29811	2.6e-79	100.0	BCL2-like 2 [sy...	synthetic construct
AAV38355	4.9e-79	99.5	BCL2-like 2 [sy...	synthetic construct

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output)
No significant homologues
Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR013280 10 26 PR01865 Apoptosis regulator

IPR013280 32 42 PR01865 Apoptosis regulator

IPR013280 44 58 PR01865 Apoptosis regulator

IPR013280 79 89 PR01865 Apoptosis regulator

IPR000712 88 100 PR01862 Apoptosis regulator Bcl-2

IPR000712 101 129 PR01862 Apoptosis regulator Bcl-2

IPR000712 130 154 PR01862 Apoptosis regulator Bcl-2

IPR013280 139 154 PR01865 Apoptosis regulator

HMMPfam IPR003093 15 41 PF02180 Apoptosis regulator Bcl-2 protein

IPR000712 55 153 PF00452 Apoptosis regulator Bcl-2

HMMSmart IPR003093 15 41 SM00265 Apoptosis regulator Bcl-2 protein

IPR000712 55 153 SM00337 Apoptosis regulator Bcl-2

ProfileScan IPR003093 19 36 PS50063 Apoptosis regulator Bcl-2 protein

IPR002475 55 155 PS50062 BCL2-like apoptosis inhibitor

ScanRegExp IPR003093 18 38 PS01260 Apoptosis regulator Bcl-2 protein

IPR000712 94 113 PS01080 Apoptosis regulator Bcl-2

IPR000712 146 157 PS01258 Apoptosis regulator Bcl-2

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR013280	10	26	PR01865	Apoptosis regulator
IPR013280	32	42	PR01865	Apoptosis regulator
IPR013280	44	58	PR01865	Apoptosis regulator
IPR013280	79	89	PR01865	Apoptosis regulator
IPR000712	88	100	PR01862	Apoptosis regulator Bcl-2
IPR000712	101	129	PR01862	Apoptosis regulator Bcl-2
IPR000712	130	154	PR01862	Apoptosis regulator Bcl-2
IPR013280	139	154	PR01865	Apoptosis regulator
HMMPfam	IPR003093	15	41	PF02180	Apoptosis regulator Bcl-2 protein
IPR000712	55	153	PF00452	Apoptosis regulator Bcl-2
HMMSmart	IPR003093	15	41	SM00265	Apoptosis regulator Bcl-2 protein
IPR000712	55	153	SM00337	Apoptosis regulator Bcl-2
ProfileScan	IPR003093	19	36	PS50063	Apoptosis regulator Bcl-2 protein
IPR002475	55	155	PS50062	BCL2-like apoptosis inhibitor
ScanRegExp	IPR003093	18	38	PS01260	Apoptosis regulator Bcl-2 protein
IPR000712	94	113	PS01080	Apoptosis regulator Bcl-2
IPR000712	146	157	PS01258	Apoptosis regulator Bcl-2

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 95 LFQGGPNWGRLVAFFVFGAALCA 117 SECONDARY 23

2 177 ASVRTVLTGAVALGALVTVGAFF 199 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	95	LFQGGPNWGRLVAFFVFGAALCA	117	SECONDARY	23
2	177	ASVRTVLTGAVALGALVTVGAFF	199	PRIMARY	23

Expression profile	Description

: Northern blot Description

Northern blot	Description

RH mapping information	Description

Chromosome No.

: 14

Experimental conditions

Panel name	: Genebridge 4
Primer_f	: AAGTAGGAGGAGAGGGGTTTC
Primer_r	: TGTGTGCCCTAGAATAAGTGG
PCR product length	: 141 bp
PCR conditions	: 95 °C15 sec62 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	YES

Length of 3'UTR	2784 bp
Genome contig ID	gi51511730f_22745876
PolyA signal sequence (AATAAA,-24)	+--------+--------+----*----+---- TAAAAACAATAAATAAAGCCCAGAAGTTTAATGAG
Flanking genome sequence (104924 - 104973)	----+--------+--------+--------+--------+----* AAGGACTGAACAGGGTTTGTGACTTCTACACTGTATAGCCTGGGGTCAGG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	14	f	22845876	22850798	4	99.0	Terminal No-hit

Gene/Protein Characteristic Table for KIAA0271

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information