HUGE

Gene/Protein Characteristic Table for KIAA0267

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00043
Accession No. :	D87743
Description :	Sodium/hydrogen exchanger 6.
HUGO Gene Name :	solute carrier family 9 (sodium/hydrogen exchanger), member 6 (SLC9A6)
Clone Name :	ha07045 [Vector Info]
Flexi ORF Clone :	pF1KA0267
Source :	Myeloblast cell line (KG-1)

Features of the cloned DNA sequence	Description

Length: 4408 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 2407 bp

Genome contig ID gi89161218f_134795337
PolyA signal sequence
(ATTAAA,-34)
+----*----+----*----+----*----+----
CATTAAAAAAGTTATAGCCTTGCAAATAACCACTC
Flanking genome sequence
(161623 - 161672)
----+----*----+----*----+----*----+----*----+----*
ACAGTATTTGAGTCACAGTTTATTTTAGTGAGACGTAAAGAGTGCTGACT

Features of the protein sequence	Description

Length: 666 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
Q92581	100.0	Sodium/hydrogen...	Homo sapiens
EAW88482	99.7	solute carrier ...	Homo sapiens
XP_001101621	99.4	similar to solu...	Macaca mulatta
BAG11159	100.0	solute carrier ...	synthetic construct
CAQ12099	96.4	solute carrier ...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB023156	5.9e-53	36.1	KIAA0939

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR002090 3 21 PR01088 Na+/H+ exchanger

IPR002090 22 40 PR01088 Na+/H+ exchanger

IPR002090 41 60 PR01088 Na+/H+ exchanger

IPR002090 61 85 PR01088 Na+/H+ exchanger

IPR002090 86 104 PR01088 Na+/H+ exchanger

IPR002090 105 131 PR01088 Na+/H+ exchanger

IPR002090 133 146 PR01088 Na+/H+ exchanger

IPR004709 147 158 PR01084 Sodium/hydrogen exchanger subfamily

IPR004709 161 175 PR01084 Sodium/hydrogen exchanger subfamily

IPR004709 176 184 PR01084 Sodium/hydrogen exchanger subfamily

IPR004709 221 231 PR01084 Sodium/hydrogen exchanger subfamily

IPR002090 264 281 PR01088 Na+/H+ exchanger

IPR002090 283 302 PR01088 Na+/H+ exchanger

IPR002090 494 520 PR01088 Na+/H+ exchanger

IPR002090 521 539 PR01088 Na+/H+ exchanger

IPR002090 545 573 PR01088 Na+/H+ exchanger

IPR002090 574 601 PR01088 Na+/H+ exchanger

IPR002090 606 627 PR01088 Na+/H+ exchanger

HMMPfam IPR006153 75 500 PF00999 Sodium/hydrogen exchanger

HMMTigr IPR004709 61 652 TIGR00840 Sodium/hydrogen exchanger subfamily

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR002090	3	21	PR01088	Na+/H+ exchanger
IPR002090	22	40	PR01088	Na+/H+ exchanger
IPR002090	41	60	PR01088	Na+/H+ exchanger
IPR002090	61	85	PR01088	Na+/H+ exchanger
IPR002090	86	104	PR01088	Na+/H+ exchanger
IPR002090	105	131	PR01088	Na+/H+ exchanger
IPR002090	133	146	PR01088	Na+/H+ exchanger
IPR004709	147	158	PR01084	Sodium/hydrogen exchanger subfamily
IPR004709	161	175	PR01084	Sodium/hydrogen exchanger subfamily
IPR004709	176	184	PR01084	Sodium/hydrogen exchanger subfamily
IPR004709	221	231	PR01084	Sodium/hydrogen exchanger subfamily
IPR002090	264	281	PR01088	Na+/H+ exchanger
IPR002090	283	302	PR01088	Na+/H+ exchanger
IPR002090	494	520	PR01088	Na+/H+ exchanger
IPR002090	521	539	PR01088	Na+/H+ exchanger
IPR002090	545	573	PR01088	Na+/H+ exchanger
IPR002090	574	601	PR01088	Na+/H+ exchanger
IPR002090	606	627	PR01088	Na+/H+ exchanger
HMMPfam	IPR006153	75	500	PF00999	Sodium/hydrogen exchanger
HMMTigr	IPR004709	61	652	TIGR00840	Sodium/hydrogen exchanger subfamily

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 21 LMRPLWLLLAVGVFDWAGASD 41 PRIMARY 21

2 70 NLLIFILLLTLTILTIWLFK 89 PRIMARY 20

3 97 HETGLAMIYGLLVGLVLRYGIHV 119 PRIMARY 23

4 139 LLVTFDPEVFFNILLPPIIFYAG 161 SECONDARY 23

5 176 ILAYAFLGTAISCFVIGSIMYGC 198 PRIMARY 23

6 216 DCLLFGAIVSATDPVTVLAIFHE 238 SECONDARY 23

7 247 ALLFGESVLNDAVAIVLSSSIVA 269 SECONDARY 23

8 288 SIGIFLGIFSGSFAMGAATGVVT 310 SECONDARY 23

9 331 FLMSWSTFLLAEAWGFTGVVAVL 353 PRIMARY 23

10 412 VGAFVAIFLGRAANIYPLSLLLN 434 SECONDARY 23

11 480 LLIVFFTVWVFGGGTTAMLSCLH 502 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	21	LMRPLWLLLAVGVFDWAGASD	41	PRIMARY	21
2	70	NLLIFILLLTLTILTIWLFK	89	PRIMARY	20
3	97	HETGLAMIYGLLVGLVLRYGIHV	119	PRIMARY	23
4	139	LLVTFDPEVFFNILLPPIIFYAG	161	SECONDARY	23
5	176	ILAYAFLGTAISCFVIGSIMYGC	198	PRIMARY	23
6	216	DCLLFGAIVSATDPVTVLAIFHE	238	SECONDARY	23
7	247	ALLFGESVLNDAVAIVLSSSIVA	269	SECONDARY	23
8	288	SIGIFLGIFSGSFAMGAATGVVT	310	SECONDARY	23
9	331	FLMSWSTFLLAEAWGFTGVVAVL	353	PRIMARY	23
10	412	VGAFVAIFLGRAANIYPLSLLLN	434	SECONDARY	23
11	480	LLIVFFTVWVFGGGTTAMLSCLH	502	PRIMARY	23

Expression profile	Description

: Northern blot Description

Northern blot	Description

RH mapping information	Description

Chromosome No.

: X

Experimental conditions

Panel name	: Genebridge 4
Primer_f	: CATTTATCCTAGTTGTCCGTG
Primer_r	: CCACTATAACATCTGTCCAAG
PCR product length	: 108 bp
PCR conditions	: 95 °C15 sec60 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	2407 bp
Genome contig ID	gi89161218f_134795337
PolyA signal sequence (ATTAAA,-34)	+--------+--------+----*----+---- CATTAAAAAAGTTATAGCCTTGCAAATAACCACTC
Flanking genome sequence (161623 - 161672)	----+--------+--------+--------+--------+----* ACAGTATTTGAGTCACAGTTTATTTTAGTGAGACGTAAAGAGTGCTGACT

Gene/Protein Characteristic Table for KIAA0267

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information