Gene/Protein Characteristic Table for KIAA0603
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Product ID ORK01983
Accession No AB011175
Description TBC1 domain family, member 4, transcript variant 1
Clone name hg01488b
Vector information
The cDNA fragment was inserted at the NotI site of the
cDNA sequence DNA sequence (5922 bp)
Predicted protein sequence (1348 aa)
Flexi ORF Clone FXC01983
Source Human adult brain
Rouge ID mKIAA0603 by Kazusa Mouse cDNA Project
Features of the cloned cDNA sequence
Description

Length: 5922 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis).

N-terminal truncation Coding interruption
cloned DNA seq No warning No warning
Features of the protein sequence
Description

Length: 1348 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
XP_522684 0 99.8 TBC1 domain fam...
Pan troglodytes
AAI51240 0 100.0 TBC1D4 protein ...
Homo sapiens
EAW80537 0 99.9 TBC1 domain fam...
Homo sapiens
O60343 0 99.8 TBC1 domain fam...
Homo sapiens
XP_879978 0 91.9 similar to TBC1...
Bos taurus
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against HUGE database (FASTA output, Multiple alignment)
Entry Exp ID% HUGE_ID
AB029031 5.5e-73 51.9 KIAA1108
D13644 1.8e-09 28.8 KIAA0019
AB028978 2.5e-08 21.1 KIAA1055
AB020689 1.6e-07 26.8 KIAA0882
AB014576 8.4e-07 23.9 KIAA0676
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
HMMPfam IPR006020 179 237 PF00640 Phosphotyrosine interaction region
IPR000195 965 1184 PF00566 RabGAP/TBC
HMMSmart IPR006020 80 240 SM00462 Phosphotyrosine interaction region
IPR006020 246 499 SM00462 Phosphotyrosine interaction region
IPR000195 965 1185 SM00164 RabGAP/TBC
ProfileScan IPR006020 415 487 PS01179 Phosphotyrosine interaction region
IPR000195 968 1162 PS50086 RabGAP/TBC

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 1145 QFSLGFVARVFDIIFLQGTEVIF 1167 PRIMARY 23
Expression profile
Description

RT-PCR
Experimental conditions
Primer_f CTCTTCACTTCCTCAGCCTAC
Primer_r TTACTTTCCTTGCCTATACCC
PCR conditions 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RH mapping information
Description

Chromosome No. 13
Experimental conditions
Panel name GeneBridge 4
Primer_f CTCTTCACTTCCTCAGCCTAC
Primer_r TTACTTTCCTTGCCTATACCC
PCR product length 74 bp
PCR conditions 95 °C15 sec62 °C60 sec30 cycles
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