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SpecieshumanProduct IDFXC00501Cloning SiteSgfI-PmeISymbolPLXNB2
Alias : MM1, Nbla00445, PLEXB2, dJ402G11.3Descriptionplexin B2
Length: 5514 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 1838 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS43035.1 0 100.0 PLXNB2 CCDS33854.1 7.3e-109 34.7 PLXND1 CCDS2765.1 1e-90 39.3 PLXNB1 CCDS33847.2 4.9e-68 33.8 PLXNA1 CCDS14752.1 2.7e-65 33.0 PLXNA3
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR001627 35 435 PF01403 Semaphorin/CD100 antigen IPR002165 469 516 PF01437 Plexin IPR002909 803 892 PF01833 Cell surface receptor IPT/TIG IPR002909 896 972 PF01833 Cell surface receptor IPT/TIG IPR002909 983 1091 PF01833 Cell surface receptor IPT/TIG IPR013548 1271 1805 PF08337 Plexin HMMSmart IPR001627 34 450 SM00630 Semaphorin/CD100 antigen IPR003659 468 519 SM00423 Plexin/semaphorin/integrin IPR003659 614 667 SM00423 Plexin/semaphorin/integrin IPR003659 759 801 SM00423 Plexin/semaphorin/integrin IPR002909 802 893 SM00429 Cell surface receptor IPT/TIG IPR002909 894 980 SM00429 Cell surface receptor IPT/TIG IPR002909 982 1092 SM00429 Cell surface receptor IPT/TIG ProfileScan IPR001627 8 466 PS51004 Semaphorin/CD100 antigen
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 1 MALQLWALTLLGLLGAGASLR 21 PRIMARY 21 2 35 NHLAVDEASGVVYLGAVNALYQL 57 SECONDARY 23 3 1196 VPLSLILPLVIVPMVVVIAVSV 1217 PRIMARY 22
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) XP_016884192 1838 604293 100.0 100.0 NP_036533 1838 604293 100.0 100.0 XP_005261968 1838 604293 100.0 100.0 XP_005261966 1838 604293 100.0 100.0 XP_006724476 1838 604293 100.0 100.0 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KSDA0315 Download>KIAA0315 5514 bp ATGGCACTGCAGCTCTGGGCCCTGACCCTGCTGGGCCTGCTGGGCGCAGGTGCCAGCCTG AGGCCCCGCAAGCTGGACTTCTTCCGCAGCGAGAAAGAGCTGAACCACCTGGCTGTGGAT GAGGCCTCAGGCGTGGTGTACCTGGGGGCGGTGAATGCCCTCTACCAGCTGGATGCGAAG CTGCAGCTGGAGCAGCAGGTGGCCACGGGCCCGGCCCTGGACAACAAGAAGTGCACGCCG CCCATCGAGGCCAGCCAGTGCCATGAGGCTGAGATGACTGACAATGTCAACCAGCTGCTG CTGCTCGACCCTCCCAGGAAGCGCCTGGTGGAGTGCGGCAGCCTCTTCAAGGGCATCTGC GCTCTGCGCGCCCTGAGCAACATCTCCCTCCGCCTGTTCTACGAGGACGGCAGCGGGGAG AAGTCTTTCGTGGCCAGCAATGATGAGGGCGTGGCCACAGTGGGGCTGGTGAGCTCCACG GGTCCTGGTGGTGACCGCGTGCTGTTTGTGGGCAAAGGCAATGGGCCACACGACAACGGC ATCATCGTGAGCACTCGGCTGTTGGACCGGACTGACAGCAGGGAGGCCTTTGAAGCCTAC ACGGACCACGCCACCTACAAGGCCGGCTACCTGTCCACCAACACACAGCAGTTCGTGGCG GCCTTCGAGGACGGCCCCTACGTCTTCTTTGTCTTCAACCAGCAGGACAAGCACCCGGCC CGGAACCGCACGCTGCTGGCACGCATGTGCAGAGAAGACCCCAACTACTACTCCTACCTG GAGATGGACCTGCAGTGCCGGGACCCCGACATCCACGCCGCTGCCTTTGGCACCTGCCTG GCCGCCTCCGTGGCTGCGCCTGGCTCTGGCAGGGTGCTATATGCTGTCTTCAGCAGAGAC AGCCGGAGCAGTGGGGGGCCCGGTGCGGGCCTCTGCCTGTTCCCGCTGGACAAGGTGCAC GCCAAGATGGAGGCCAACCGCAACGCCTGTTACACAGGCACCCGGGAGGCCCGTGACATC TTCTACAAGCCCTTCCACGGCGATATCCAGTGCGGCGGCCACGCGCCGGGCTCCAGCAAG AGCTTCCCATGTGGCTCGGAGCACCTGCCCTACCCGCTGGGCAGCCGCGACGGGCTCAGA GGCACAGCCGTGCTGCAGCGTGGAGGCCTGAACCTCACGGCCGTGACGGTCGCCGCCGAG AACAACCACACTGTTGCTTTTCTGGGCACCTCTGATGGCCGGATCCTCAAGGTGTACCTC ACCCCAGATGGCACCTCCTCAGAGTACGACTCTATCCTTGTGGAGATAAACAAGAGAGTC AAGCGCGACCTGGTACTGTCTGGAGACCTGGGCAGCCTGTACGCCATGACCCAGGACAAG GTGTTCCGGCTGCCGGTGCAGGAGTGCCTGAGCTACCCGACCTGCACCCAGTGCCGCGAC TCCCAGGACCCCTACTGCGGCTGGTGCGTCGTCGAGGGACGATGCACCCGGAAGGCCGAG TGTCCGCGGGCCGAGGAGGCCAGCCACTGGCTGTGGAGCCGAAGCAAGTCCTGCGTGGCC GTCACCAGCGCCCAGCCACAGAACATGAGCCGGCGGGCCCAGGGGGAGGTGCAGCTGACC GTCAGCCCCCTCCCTGCCCTGAGCGAGGAGGACGAGTTGCTGTGCCTTTTTGGGGAGTCG CCGCCACACCCCGCCCGCGTGGAGGGCGAGGCCGTCATCTGCAACTCCCCAAGCAGCATC CCCGTCACACCGCCAGGCCAGGACCACGTGGCCGTGACCATCCAGCTCCTCCTTAGACGA GGCAACATCTTCCTCACGTCCTACCAGTACCCCTTCTACGACTGCCGCCAGGCCATGAGC CTGGAGGAGAACCTGCCGTGCATCTCCTGCGTGAGCAACCGCTGGACCTGCCAGTGGGAC CTGCGCTACCACGAGTGCCGGGAGGCTTCGCCCAACCCTGAGGACGGCATCGTCCGTGCC CACATGGAGGACAGCTGTCCCCAGTTCCTGGGACCCAGCCCCCTGGTGATCCCCATGAAC CACGAGACAGATGTGAACTTCCAGGGCAAGAACCTGGACACCGTGAAGGGTTCCTCCCTG CACGTGGGCAGTGACTTGCTCAAGTTCATGGAGCCGGTGACCATGCAGGAATCTGGGACC TTCGCCTTTCGGACCCCAAAGCTGTCCCACGATGCCAACGAGACGCTGCCCCTGCACCTC TACGTCAAGTCTTACGGCAAGAATATCGACAGCAAGCTCCATGTGACCCTCTACAACTGC TCCTTTGGCCGCAGCGACTGCAGCCTGTGCCGGGCCGCTAACCCCGACTACAGGTGTGCG TGGTGCGGGGGCCAGAGCAGGTGCGTGTATGAGGCCCTGTGCAACACCACCTCCGAGTGC CCGCCGCCCGTCATCACCAGGATCCAGCCTGAGACGGGCCCCCTGGGTGGGGGCATCCGC ATCACCATCCTGGGGTCCAATTTGGGCGTCCAAGCAGGGGACATCCAGAGGATCTCTGTG GCCGGCCGGAACTGCTCCTTTCAGCCGGAACGTTACTCCGTGTCCACCCGGATCGTGTGT GTGATCGAGGCTGCGGAGACGCCTTTCACGGGGGGTGTCGAGGTGGACGTCTTCGGGAAA CTGGGCCGTTCGCCTCCCAATGTCCAGTTCACCTTCCAACAGCCCAAGCCTCTCAGTGTG GAGCCGCAGCAGGGACCGCAGGCGGGCGGCACCACACTGACCATCCACGGCACCCACCTG GACACGGGCTCCCAGGAGGACGTGCGGGTGACCCTCAACGGCGTCCCGTGTAAAGTGACG AAGTTTGGGGCGCAGCTCCAGTGTGTCACTGGCCCCCAGGCGACACGGGGCCAGATGCTT CTGGAGGTCTCCTACGGGGGGTCCCCCGTGCCCAACCCCGGCATCTTCTTCACCTACCGC GAAAACCCCGTACTGCGAGCCTTCGAGCCGCTACGAAGCTTTGCCAGTGGTGGCCGCAGC ATCAACGTCACGGGTCAGGGCTTCAGCCTGATCCAGAGGTTTGCCATGGTGGTCATCGCG GAGCCCCTGCAGTCCTGGCAGCCGCCGCGGGAGGCTGAATCCCTGCAGCCCATGACGGTG GTGGGTACAGACTACGTGTTCCACAATGACACCAAGGTCGTCTTCCTGTCCCCGGCTGTG CCTGAGGAGCCAGAGGCCTACAACCTCACGGTGCTGATCGAGATGGACGGGCACCGTGCC CTGCTCAGAACAGAGGCCGGGGCCTTCGAGTACGTGCCTGACCCCACCTTTGAGAACTTC ACAGGTGGCGTCAAGAAGCAGGTCAACAAGCTCATCCACGCCCGGGGCACCAATCTGAAC AAGGCGATGACGCTGCAGGAGGCCGAGGCCTTCGTGGGTGCCGAGCGCTGCACCATGAAG ACGCTGACGGAGACCGACCTGTACTGTGAGCCCCCGGAGGTGCAGCCCCCGCCCAAGCGG CGGCAGAAACGAGACACCACACACAACCTGCCCGAGTTCATTGTGAAGTTCGGCTCTCGC GAGTGGGTGCTGGGCCGCGTGGAGTACGACACACGGGTGAGCGACGTGCCGCTCAGCCTC ATCTTGCCGCTGGTCATCGTGCCCATGGTGGTCGTCATCGCGGTGTCTGTCTACTGCTAC TGGAGGAAGAGCCAGCAGGCCGAACGAGAGTATGAGAAGATCAAGTCCCAGCTGGAGGGC CTGGAGGAGAGCGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTGATGATCGAGATG GAGGACCAGACCAACGACGTGCACGAGGCCGGCATCCCCGTGCTGGACTACAAGACCTAC ACCGACCGCGTCTTCTTCCTGCCCTCCAAGGACGGCGACAAGGACGTGATGATCACCGGC AAGCTGGACATCCCTGAGCCGCGGCGGCCGGTGGTGGAGCAGGCCCTCTACCAGTTCTCC AACCTGCTGAACAGCAAGTCTTTCCTCATCAATTTCATCCACACCCTGGAGAACCAGCGG GAGTTCTCGGCCCGCGCCAAGGTCTACTTCGCGTCCCTGCTGACGGTGGCGCTGCACGGG AAACTGGAGTACTACACGGACATCATGCACACGCTCTTCCTGGAGCTCCTGGAGCAGTAC GTGGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGTCTGAGACTGTGGTGGAGAGGATG CTGTCCAACTGGATGTCCATCTGCCTGTACCAGTACCTCAAGGACAGTGCCGGGGAGCCC CTGTACAAGCTCTTCAAGGCCATCAAACATCAGGTGGAAAAGGGCCCGGTGGATGCGGTA CAGAAGAAGGCCAAGTACACTCTCAACGACACGGGGCTGCTGGGGGATGATGTGGAGTAC GCACCCCTGACGGTGAGCGTGATCGTGCAGGACGAGGGAGTGGACGCCATCCCGGTGAAG GTCCTCAACTGTGACACCATCTCCCAGGTCAAGGAGAAGATCATTGACCAGGTGTACCGT GGGCAGCCCTGCTCCTGCTGGCCCAGGCCAGACAGCGTGGTCCTGGAGTGGCGTCCGGGC TCCACAGCGCAGATCCTGTCGGACCTGGACCTGACGTCACAGCGGGAGGGCCGGTGGAAG CGCGTCAACACCCTTATGCACTACAATGTCCGGGATGGAGCCACCCTCATCCTGTCCAAG GTGGGGGTCTCCCAGCAGCCGGAGGACAGCCAGCAGGACCTGCCTGGGGAGCGCCATGCC CTCCTGGAGGAGGAGAACCGGGTGTGGCACCTGGTGCGGCCGACCGACGAGGTGGACGAG GGCAAGTCCAAGAGAGGCAGCGTGAAAGAGAAGGAGCGGACGAAGGCCATCACCGAGATC TACCTGACGCGGCTGCTCTCAGTCAAGGGCACACTGCAGCAGTTTGTGGACAACTTCTTC CAGAGCGTGCTGGCGCCTGGGCACGCGGTGCCACCTGCAGTCAAGTACTTCTTCGACTTC CTGGACGAGCAGGCAGAGAAGCACAACATCCAGGATGAAGACACCATCCACATCTGGAAG ACGAACAGCTTACCGCTCCGGTTCTGGGTGAACATCCTCAAGAACCCCCACTTCATCTTT GACGTGCATGTCCACGAGGTGGTGGACGCCTCGCTGTCAGTCATCGCGCAGACCTTCATG GATGCCTGCACGCGCACGGAGCATAAGCTGAGCCGCGATTCTCCCAGCAACAAGCTGCTG TACGCCAAGGAGATCTCCACCTACAAGAAGATGGTGGAGGATTACTACAAGGGGATCCGG CAGATGGTGCAGGTCAGCGACCAGGACATGAACACACACCTGGCAGAGATTTCCCGGGCG CACACGGACTCCTTGAACACCCTCGTGGCACTCCACCAGCTCTACCAATACACGCAGAAG TACTATGACGAGATCATCAATGCCTTGGAGGAGGATCCTGCCGCCCAGAAGATGCAGCTG GCCTTCCGCCTGCAGCAGATTGCCGCTGCACTGGAGAACAAGGTCACTGACCTC
Cloned ORF protein sequence for pF1KSDA0315 Download>KIAA0315 1838 aa MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL
Nucleotide Sequence (with vector) for pF1KSDA0315 Download>pF1KSDA0315 8653 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCTTTCGAAGGAGAT AGAACCATGGCACTGCAGCTCTGGGCCCTGACCCTGCTGGGCCTGCTGGGCGCAGGTGCC AGCCTGAGGCCCCGCAAGCTGGACTTCTTCCGCAGCGAGAAAGAGCTGAACCACCTGGCT GTGGATGAGGCCTCAGGCGTGGTGTACCTGGGGGCGGTGAATGCCCTCTACCAGCTGGAT GCGAAGCTGCAGCTGGAGCAGCAGGTGGCCACGGGCCCGGCCCTGGACAACAAGAAGTGC ACGCCGCCCATCGAGGCCAGCCAGTGCCATGAGGCTGAGATGACTGACAATGTCAACCAG CTGCTGCTGCTCGACCCTCCCAGGAAGCGCCTGGTGGAGTGCGGCAGCCTCTTCAAGGGC ATCTGCGCTCTGCGCGCCCTGAGCAACATCTCCCTCCGCCTGTTCTACGAGGACGGCAGC GGGGAGAAGTCTTTCGTGGCCAGCAATGATGAGGGCGTGGCCACAGTGGGGCTGGTGAGC TCCACGGGTCCTGGTGGTGACCGCGTGCTGTTTGTGGGCAAAGGCAATGGGCCACACGAC AACGGCATCATCGTGAGCACTCGGCTGTTGGACCGGACTGACAGCAGGGAGGCCTTTGAA GCCTACACGGACCACGCCACCTACAAGGCCGGCTACCTGTCCACCAACACACAGCAGTTC GTGGCGGCCTTCGAGGACGGCCCCTACGTCTTCTTTGTCTTCAACCAGCAGGACAAGCAC CCGGCCCGGAACCGCACGCTGCTGGCACGCATGTGCAGAGAAGACCCCAACTACTACTCC TACCTGGAGATGGACCTGCAGTGCCGGGACCCCGACATCCACGCCGCTGCCTTTGGCACC TGCCTGGCCGCCTCCGTGGCTGCGCCTGGCTCTGGCAGGGTGCTATATGCTGTCTTCAGC AGAGACAGCCGGAGCAGTGGGGGGCCCGGTGCGGGCCTCTGCCTGTTCCCGCTGGACAAG GTGCACGCCAAGATGGAGGCCAACCGCAACGCCTGTTACACAGGCACCCGGGAGGCCCGT GACATCTTCTACAAGCCCTTCCACGGCGATATCCAGTGCGGCGGCCACGCGCCGGGCTCC AGCAAGAGCTTCCCATGTGGCTCGGAGCACCTGCCCTACCCGCTGGGCAGCCGCGACGGG CTCAGAGGCACAGCCGTGCTGCAGCGTGGAGGCCTGAACCTCACGGCCGTGACGGTCGCC GCCGAGAACAACCACACTGTTGCTTTTCTGGGCACCTCTGATGGCCGGATCCTCAAGGTG TACCTCACCCCAGATGGCACCTCCTCAGAGTACGACTCTATCCTTGTGGAGATAAACAAG AGAGTCAAGCGCGACCTGGTACTGTCTGGAGACCTGGGCAGCCTGTACGCCATGACCCAG GACAAGGTGTTCCGGCTGCCGGTGCAGGAGTGCCTGAGCTACCCGACCTGCACCCAGTGC CGCGACTCCCAGGACCCCTACTGCGGCTGGTGCGTCGTCGAGGGACGATGCACCCGGAAG GCCGAGTGTCCGCGGGCCGAGGAGGCCAGCCACTGGCTGTGGAGCCGAAGCAAGTCCTGC GTGGCCGTCACCAGCGCCCAGCCACAGAACATGAGCCGGCGGGCCCAGGGGGAGGTGCAG CTGACCGTCAGCCCCCTCCCTGCCCTGAGCGAGGAGGACGAGTTGCTGTGCCTTTTTGGG GAGTCGCCGCCACACCCCGCCCGCGTGGAGGGCGAGGCCGTCATCTGCAACTCCCCAAGC AGCATCCCCGTCACACCGCCAGGCCAGGACCACGTGGCCGTGACCATCCAGCTCCTCCTT AGACGAGGCAACATCTTCCTCACGTCCTACCAGTACCCCTTCTACGACTGCCGCCAGGCC ATGAGCCTGGAGGAGAACCTGCCGTGCATCTCCTGCGTGAGCAACCGCTGGACCTGCCAG TGGGACCTGCGCTACCACGAGTGCCGGGAGGCTTCGCCCAACCCTGAGGACGGCATCGTC CGTGCCCACATGGAGGACAGCTGTCCCCAGTTCCTGGGACCCAGCCCCCTGGTGATCCCC ATGAACCACGAGACAGATGTGAACTTCCAGGGCAAGAACCTGGACACCGTGAAGGGTTCC TCCCTGCACGTGGGCAGTGACTTGCTCAAGTTCATGGAGCCGGTGACCATGCAGGAATCT GGGACCTTCGCCTTTCGGACCCCAAAGCTGTCCCACGATGCCAACGAGACGCTGCCCCTG CACCTCTACGTCAAGTCTTACGGCAAGAATATCGACAGCAAGCTCCATGTGACCCTCTAC AACTGCTCCTTTGGCCGCAGCGACTGCAGCCTGTGCCGGGCCGCTAACCCCGACTACAGG TGTGCGTGGTGCGGGGGCCAGAGCAGGTGCGTGTATGAGGCCCTGTGCAACACCACCTCC GAGTGCCCGCCGCCCGTCATCACCAGGATCCAGCCTGAGACGGGCCCCCTGGGTGGGGGC ATCCGCATCACCATCCTGGGGTCCAATTTGGGCGTCCAAGCAGGGGACATCCAGAGGATC TCTGTGGCCGGCCGGAACTGCTCCTTTCAGCCGGAACGTTACTCCGTGTCCACCCGGATC GTGTGTGTGATCGAGGCTGCGGAGACGCCTTTCACGGGGGGTGTCGAGGTGGACGTCTTC GGGAAACTGGGCCGTTCGCCTCCCAATGTCCAGTTCACCTTCCAACAGCCCAAGCCTCTC AGTGTGGAGCCGCAGCAGGGACCGCAGGCGGGCGGCACCACACTGACCATCCACGGCACC CACCTGGACACGGGCTCCCAGGAGGACGTGCGGGTGACCCTCAACGGCGTCCCGTGTAAA GTGACGAAGTTTGGGGCGCAGCTCCAGTGTGTCACTGGCCCCCAGGCGACACGGGGCCAG ATGCTTCTGGAGGTCTCCTACGGGGGGTCCCCCGTGCCCAACCCCGGCATCTTCTTCACC TACCGCGAAAACCCCGTACTGCGAGCCTTCGAGCCGCTACGAAGCTTTGCCAGTGGTGGC CGCAGCATCAACGTCACGGGTCAGGGCTTCAGCCTGATCCAGAGGTTTGCCATGGTGGTC ATCGCGGAGCCCCTGCAGTCCTGGCAGCCGCCGCGGGAGGCTGAATCCCTGCAGCCCATG ACGGTGGTGGGTACAGACTACGTGTTCCACAATGACACCAAGGTCGTCTTCCTGTCCCCG GCTGTGCCTGAGGAGCCAGAGGCCTACAACCTCACGGTGCTGATCGAGATGGACGGGCAC CGTGCCCTGCTCAGAACAGAGGCCGGGGCCTTCGAGTACGTGCCTGACCCCACCTTTGAG AACTTCACAGGTGGCGTCAAGAAGCAGGTCAACAAGCTCATCCACGCCCGGGGCACCAAT CTGAACAAGGCGATGACGCTGCAGGAGGCCGAGGCCTTCGTGGGTGCCGAGCGCTGCACC ATGAAGACGCTGACGGAGACCGACCTGTACTGTGAGCCCCCGGAGGTGCAGCCCCCGCCC AAGCGGCGGCAGAAACGAGACACCACACACAACCTGCCCGAGTTCATTGTGAAGTTCGGC TCTCGCGAGTGGGTGCTGGGCCGCGTGGAGTACGACACACGGGTGAGCGACGTGCCGCTC AGCCTCATCTTGCCGCTGGTCATCGTGCCCATGGTGGTCGTCATCGCGGTGTCTGTCTAC TGCTACTGGAGGAAGAGCCAGCAGGCCGAACGAGAGTATGAGAAGATCAAGTCCCAGCTG GAGGGCCTGGAGGAGAGCGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTGATGATC GAGATGGAGGACCAGACCAACGACGTGCACGAGGCCGGCATCCCCGTGCTGGACTACAAG ACCTACACCGACCGCGTCTTCTTCCTGCCCTCCAAGGACGGCGACAAGGACGTGATGATC ACCGGCAAGCTGGACATCCCTGAGCCGCGGCGGCCGGTGGTGGAGCAGGCCCTCTACCAG TTCTCCAACCTGCTGAACAGCAAGTCTTTCCTCATCAATTTCATCCACACCCTGGAGAAC CAGCGGGAGTTCTCGGCCCGCGCCAAGGTCTACTTCGCGTCCCTGCTGACGGTGGCGCTG CACGGGAAACTGGAGTACTACACGGACATCATGCACACGCTCTTCCTGGAGCTCCTGGAG CAGTACGTGGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGTCTGAGACTGTGGTGGAG AGGATGCTGTCCAACTGGATGTCCATCTGCCTGTACCAGTACCTCAAGGACAGTGCCGGG GAGCCCCTGTACAAGCTCTTCAAGGCCATCAAACATCAGGTGGAAAAGGGCCCGGTGGAT GCGGTACAGAAGAAGGCCAAGTACACTCTCAACGACACGGGGCTGCTGGGGGATGATGTG GAGTACGCACCCCTGACGGTGAGCGTGATCGTGCAGGACGAGGGAGTGGACGCCATCCCG GTGAAGGTCCTCAACTGTGACACCATCTCCCAGGTCAAGGAGAAGATCATTGACCAGGTG TACCGTGGGCAGCCCTGCTCCTGCTGGCCCAGGCCAGACAGCGTGGTCCTGGAGTGGCGT CCGGGCTCCACAGCGCAGATCCTGTCGGACCTGGACCTGACGTCACAGCGGGAGGGCCGG TGGAAGCGCGTCAACACCCTTATGCACTACAATGTCCGGGATGGAGCCACCCTCATCCTG TCCAAGGTGGGGGTCTCCCAGCAGCCGGAGGACAGCCAGCAGGACCTGCCTGGGGAGCGC CATGCCCTCCTGGAGGAGGAGAACCGGGTGTGGCACCTGGTGCGGCCGACCGACGAGGTG GACGAGGGCAAGTCCAAGAGAGGCAGCGTGAAAGAGAAGGAGCGGACGAAGGCCATCACC GAGATCTACCTGACGCGGCTGCTCTCAGTCAAGGGCACACTGCAGCAGTTTGTGGACAAC TTCTTCCAGAGCGTGCTGGCGCCTGGGCACGCGGTGCCACCTGCAGTCAAGTACTTCTTC GACTTCCTGGACGAGCAGGCAGAGAAGCACAACATCCAGGATGAAGACACCATCCACATC TGGAAGACGAACAGCTTACCGCTCCGGTTCTGGGTGAACATCCTCAAGAACCCCCACTTC ATCTTTGACGTGCATGTCCACGAGGTGGTGGACGCCTCGCTGTCAGTCATCGCGCAGACC TTCATGGATGCCTGCACGCGCACGGAGCATAAGCTGAGCCGCGATTCTCCCAGCAACAAG CTGCTGTACGCCAAGGAGATCTCCACCTACAAGAAGATGGTGGAGGATTACTACAAGGGG ATCCGGCAGATGGTGCAGGTCAGCGACCAGGACATGAACACACACCTGGCAGAGATTTCC CGGGCGCACACGGACTCCTTGAACACCCTCGTGGCACTCCACCAGCTCTACCAATACACG CAGAAGTACTATGACGAGATCATCAATGCCTTGGAGGAGGATCCTGCCGCCCAGAAGATG CAGCTGGCCTTCCGCCTGCAGCAGATTGCCGCTGCACTGGAGAACAAGGTCACTGACCTC TACGTAGTTTAAACGAATTCGAGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGG CATGCAAGCTGATCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCAC CGCTGAGCAATAACTAGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTT GCTGAAAGGAGGAACTATATCCGGTTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTA TCGCCATGTAAGCCCACTGCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGT CCAGATAGCCCAGTAGCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTT CTACGTGTTCCGCTTCCTTTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCT TCAAAAGAATTGCCAGCTGGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAAC TGGATGGCTTTCTTGCCGCCAAGGATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAG ACAGGATGACGGTCGTTTCGCATGCTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCC GCTTGGGTGGAGAGGCTATTCGGCTATGACTGGGCACAACAGACAATCGGCTGCTCTGAT GCCGCCGTGTTCCGGCTGTCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTG TCCGGTGCCCTGAATGAACTGCAGGACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACG GGCGTTCCTTGCGCAGCTGTGCTCGACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTA TTGGGCGAAGTGCCGGGGCAGGATCTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTA TCCATCATGGCTGATGCAATGCGGCGGCTGCATACGCTTGATCCGGCTACCTGCCCATTC GACCACCAAGCGAAACATCGCATCGAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTC GATCAGGATGATCTGGACGAAGAGCATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGG CTCAAGGCGCGTATGCCGGATGGTGAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTG CCGAATATCATGGTGGAAAATGGCCGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGT GTGGCGGACCGCTATCAGGACATAGCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGC GGCGAATGGGCTGACCGCTTCCTCGTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGC ATCGCCTTCTATCGCCTTCTTGACGAGTTCTTCTGAGCGGGACTCTGGGGTTCGCGAAAT GACCGACCAAGCGACGCCCAACCGGTATCAGCTCACTCAAAGGCGGTAATACGGTTATCC ACAGAATCAGGGGATAACGCAGGAAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGG AACCGTAAAAAGGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCAT CACAAAAATCGACGCTCAAGTCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAG GCGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGA TACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGG TATCTCAGTTCGGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTT CAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACAC GACTTATCGCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGC GGTGCTACAGAGTTCTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGGACAGTATTT GGTATCTGCGCTCTGCTGAAGCCAGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCC GGCAAACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGC AGAAAAAAAGGATTTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGG AACGAAAACTCACGTTAAGGGATTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAG ATCCTTTTATAGTCCGGAAATACAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTG AAACCATGAAAAATGGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCT GGTTGCATAGGTATTCATACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGG TGGTTTGTTGCCATTTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGT GCGTACAATTAAGGGATTATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGAT AAACCGCAGTACTCCGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTG ATACAGATTAAATCAGAACGCAGAAGCGGTCTGATAAAACAGAATTTGCCTGGCGGCAGT AGCGCGGTGGTCCCACCTGACCCCATGCCGAACTCAGAAGTGAAACGCCGTAGCGCCGAT GGTAGTGTGGGGTCTCCCCATGCGAGAGTAGGGAACTGCCAGGCATCAAATAAAACGAAA GGCTCAGTCGAAAGACTGGGCCTTTCGTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCT GAGTAGGACAAATCCGCCGGGAGCGGATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTG GCGGGCAGGACGCCCGCCATAAACTGCCAGGCATCAAATTAAGCAGAAGGCCATCCTGAC GGATGGCCTTTTTGCGTTTCTACAAACTCTTTTGTTTATTTTTCTAAATACATTCAAATA TGTATCCGCTCAT
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