Gene/Protein Characteristic Table for KIAA1723
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Product ID ORK00902
Accession No AB051510
Description DLC1 Rho GTPase activating protein, transcript variant 1
Clone name pf00881
Vector information
The cDNA fragment was inserted at the SalI-NotI site of the ...
cDNA sequence DNA sequence (7365 bp)
Predicted protein sequence (1554 aa)
Flexi ORF Clone FXC00902
Source Human brain (hippocampus)
Features of the cloned cDNA sequence
Description

Length: 7365 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis).

N-terminal truncation Coding interruption
cloned DNA seq No warning No warning
Integrity of 3' end
Length of 3'UTR 2448 bp
Genome contig ID gi51511724r_12885362
PolyA signal sequence
(AATAAA,-25)
+----*----+----*----+----*----+----
GTAGGCACCTAATAAATTTATTATTTGCTATACTG
Flanking genome sequence
(99881 - 99832)
----+----*----+----*----+----*----+----*----+----*
AACTGATTGGATTAGCTTCTGTTACTGCAAAGGGAAGAGCATCTAGGATC

Ensembl ContigView (Add our DAS server as a DAS source)


Chr f/r start end exon identity class
Ensembl gnome browser 8 r 12985243 13416686 18 99.3 Perfect prediction
Features of the protein sequence
Description

Length: 1554 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
BAG10131 0 100.0 Rho GTPase-acti...
synthetic construct
EAW63855 0 99.9 deleted in live...
Homo sapiens
BAF84371 0 99.8 unnamed protein...
Homo sapiens
AAH54511 0 99.7 Deleted in live...
Homo sapiens
ACE86794 0 99.7 deleted in live...
synthetic construct
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against HUGE database (FASTA output, Multiple alignment)
Entry Exp ID% HUGE_ID
D80011 1.1e-104 42.5 KIAA0189
AB037735 8.3e-08 25.5 KIAA1314
D50921 1.2e-07 30.4 KIAA0131
AB014572 1.6e-07 32.3 KIAA0672
AB051509 3e-07 30.1 KIAA1722
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
HMMPfam IPR011510 474 541 PF07647 Sterile alpha motif homology 2
IPR000198 1118 1264 PF00620 RhoGAP
IPR002913 1349 1548 PF01852 Lipid-binding START
HMMSmart IPR000198 1115 1307 SM00324 RhoGAP
IPR002913 1349 1550 SM00234 Lipid-binding START
ProfileScan IPR000198 1104 1310 PS50238 RhoGAP
IPR002913 1340 1525 PS50848 Lipid-binding START
Expression profile
Description

RT-PCR-ELISA
Experimental conditions
Primer_f CGCTTTATTTGCAGTGTGTTG
Primer_r AGACATCTATTGCCATTCAGC
PCR conditions 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RH mapping information
Description

Chromosome No. 8
Experimental conditions
Panel name unigene
Primer_f -
Primer_r -
PCR product length -
PCR conditions -
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