論文

1. M2 macrophage-derived TGF-β induces age-associated loss of adipogenesis through progenitor cell senescence.
   Zeng X, Wang TW, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Johmura Y, Nakanishi M.
   Mol Metab. 2024 Apr 22:101943. doi: 10.1016/j.molmet.2024.101943
   
2. Intracellular acidification and glycolysis modulate inflammatory pathway in senescent cells.
   Kawakami S, Johmura Y, Nakanishi M.
   J Biochem. 2024 Apr 2:mvae032. doi: 10.1093/jb/mvae032
   
3. Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice
   Cell Rep Med. 2024 Mar 195(3):101449. doi: 10.1016/j.xcrm.2024.101449.
   
4. Autophagy inhibition-induced cytosolic DNA sensing combined with differentiation therapy induces irreversible myeloid differentiation in leukemia cells.
   Baba T, Tomaru U, Hirao A, Mukaida N, Johmura Y.
   Cancer Res Commun. 2024 Mar 11. doi: 10.1158/2767-9764.CRC-23-0507
   
5. Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts.
   Suda K, Moriyama Y, Razali N, Chiu Y, Masukagami Y, Nishimura K, Barbee H, Takase H, Sugiyama S, Yamazaki Y, Sato Y, Higashiyama T, Johmura Y, Nakanishi M, Kono K.
   Nat Aging. 2024 Feb 22. doi: 10.1038/s43587-024-00575-6.
   
6. Discovery of a structural class of antibiotics with explainable deep learning.
   Wong F, Zheng EJ, Valeri JA, Donghia NM, Anahtar MN, Omori S, Li A, Cubillos-Ruiz A, Krishnan A, Jin W, Manson AL, Friedrichs J, Helbig R, Hajian B, Fiejtek DK, Wagner FF, Soutter HH, Earl AM, Stokes JM, Renner LD, Collins JJ.
   Nature. 2024 Feb;626(7997):177-185. doi: 10.1038/s41586-023-06887-8
   
7. Quantitative Analysis of Therapeutic Antibody Interactions with Fcγ Receptors Using High-Speed Atomic Force Microscopy.
   Yanaka S, Watanabe H, Yogo R, Kongsema M, Kondo S, Yagi H, Uchihashi T, Kato K.
   Biol Pharm Bull. 2024 Jan 31;47(1):334-338. doi: 10.1248/bpb.b23-00751.
   
8. UGGT1/2-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins
   Ninagawa, Matsuo M, Ying D, Aso S, Matsushita K, Fueki A, Saito S, Imami K, Kizuka Y, Sakuma T, Yamamoto T, Yagi H, Kato K, Mori K.
   eLife 2023 doi.org/10.7554/eLife.93117.1
   
9. Three-dimensional analysis of the intracellular architecture by scanning electron microscopy.
   Koga D, Kusumi S, Yagi H, Kato K.
   Microscopy (Oxf). 2023 doi: 10.1093/jmicro/dfad050.
   
10. N-linked glycosylation of flavivirus E protein contributes to viral particle formation.
    Ishida K, Yagi H, Kato Y, Morita E.
    PLoS Pathog. 2023 Oct 11;19(10):e1011681. doi: 10.1371/journal.ppat.1011681.
    
11. LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits.
    Li D, Johmura Y(corresponding authors), Morimoto S, Doi M, Nakanishi K, Ozawa M, Tsunekawa Y, Inoue-Yamauchi A, Naruse H, Matsukawa T, Takeshita Y, Suzuki N, Aoki M, Nishiyama A, Zeng X, Konishi C, Suzuki N, Nishiyama A, Harris AS, Morita M, Yamaguchi K, Furukawa Y, Nakai K, Tsuji S, Yamazaki S, Yamanashi Y, Shimada S, Okada T, Okano H, Toda T, Nakanishi M(corresponding authors).
    Nat Aging. 2023 Jul 20. doi: 10.1038/s43587-023-00464-4.
    
12. In vivo dynamics of senescence in rhabdomyolysis-induced acute kidney injury.
    Harris AS, Aratani S, Johmura Y, Suzuki N, Dan L, Nakanishi M.
    Biochem Biophys Res Commun. 2023 Jun 15;673:121-130. doi: 10.1016/j.bbrc.2023.06.046.
13. The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR-deficient mice
    Andrea C. Postmus, Janine K. Kruit, Roos E. Eilers, Rick Havinga, Mirjam H. Koster, Yoshikazu Johmura, Makoto Nakanishi, Bart van de Sluis, Johan W. Jonker.
    Toxicol Appl Pharmacol. 2023 Jun 1;468:116531. doi:10.1016/j.taap.2023.116531. Epub 2023 Apr 23.
14. The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming
    Shogo Sato, Tomoaki Hishida, Kenichiro Kinouchi, Fumiaki Hatanaka, Yumei Li, Quy Nguyen, Yumay Chen, Ping H Wang, Kai Kessenbrock, Wei Li, Juan Carlos Izpisua Belmonte, Paolo Sassone-Corsi.
    Cell Rep. 2023 May 31; 42(6):112590. doi: 10.1016/j.celrep.2023.112590. PMID: 37261952
15. Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 –β-catenin cascade to promote liver tumorigenesis.
    Sinha S, Aizawa S, Nakano Y, Rialdi A, Choi HY, Shrestha R, Pan SQ, Chen Y, Li M, Kapelanski-Lamoureux A, Yochum G, Sher L, Monga SP, Lazaris A, Machida K, Karin M, Guccione E, Tsukamoto H.
    Nat Commun. 2023 May 8;14(1):2651. doi: 10.1038/s41467-023-38406-8
16. Discovering small-molecule senolytics with deep neural networks
    Felix Wong, Satotaka Omori (Co-first authors) , Nina M Donghia , Erica J Zheng , James J Collins.
    Nat Aging. 2023 May 4. doi: 10.1038/s43587-023-00415-z. Online ahead of print.

著書

1. 「技術講座 ・糖鎖構造のオミクス解析」、共著、矢木 宏和, 加藤 晃一、月刊「細胞」（ニュー・サイエンス社）2024年
2. 「マルチオミクス解析によるセノリティクス戦略」、共著、大森徳貴, 城村由和、実験医学（羊土社）2023年
3. 「細胞老化を標的とした治療」、共著、馬場智久, 城村由和、月刊「腫瘍内科」（科学評論社）2023年
4. 「低分子化合物による老化細胞除去の現状と未来」、共著、大森徳貴, 城村由和、医学のあゆみ（医歯薬出版株式会社）2023年
5. 「抗PD-1抗体による老化細胞の除去」、共著、中野泰博, 城村由和、バイオサイエンスとインダストリー（バイオインダストリー協会）2023年

総説

1. Using human induced pluripotent stem cell-derived liver cells to investigate the mechanisms of liver fibrosis in vitro
   Yuta Koui, Taketomo Kido
   Biochem Soc Trans. 2023, 51, 1271-1277
2. Current status and challenges in structural lycobiology
   K.Kato and H.Yagi
   Trends in Carbohydrate Research, 2023, 15, 38-46