ROUGE

Gene/Protein Characteristic Table for mKIAA1123

Link to : HUGE \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK129294
Description :	calcium channel, voltage-dependent, T type, alpha 1G subunit.
Clone Name :	mbg04765 [Vector Info]
Source :	Mouse brain

Features of the cloned DNA sequence	Description

Length: 4944 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 772 bp

Genome contig ID gi65527427r_94129459
PolyA signal sequence
(AATAAA,-33)
+----*----+----*----+----*----+----
AAAATAAAAAGTTAATTACAGTCCAGAGTAAAAGC
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AAAGGGGATGCAGAGATAGGCGTGTTTAGAGGCCTGGAGAAAGGAAGTGG

Genomic structure deduced by Blast search against draft genome sequences
Comparison with the corresponding KIAA cDNA.

KIAA Alignment based on:

KIAA1123 DNA sequence, AA sequence, Physical map

KIAA	Alignment based on:
KIAA1123	DNA sequence, AA sequence, Physical map

Features of the protein sequence	Description

Coding region: 3..4172
Length: 1389 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
CAI25956	100.0	calcium channel...	Mus musculus
CAI25958	99.4	calcium channel...	Mus musculus
CAB40793	99.4	voltage-gated c...	Mus musculus
AAD26858	98.3	T-type calcium ...	Rattus norvegicus
AAH57399	98.3	Cacna1g protein...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AK122452	1.5e-65	55.4	mKIAA4255

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR005821 411 638 PF00520 Ion transport protein

IPR005821 744 952 PF00520 Ion transport protein

ProfileScan IPR005820 1 68 PS50266 Cation channel

NULL 150 248 PS50324 NULL

IPR005820 378 642 PS50266 Cation channel

IPR001682 480 642 PS50273 Ca2+/Na+ channel

IPR002111 711 956 PS50272 Cation (not K+) channel

IPR005820 713 956 PS50266 Cation channel

IPR001682 811 956 PS50273 Ca2+/Na+ channel

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR005821	411	638	PF00520	Ion transport protein
IPR005821	744	952	PF00520	Ion transport protein
ProfileScan	IPR005820	1	68	PS50266	Cation channel
NULL	150	248	PS50324	NULL
IPR005820	378	642	PS50266	Cation channel
IPR001682	480	642	PS50273	Ca2+/Na+ channel
IPR002111	711	956	PS50272	Cation (not K+) channel
IPR005820	713	956	PS50266	Cation channel
IPR001682	811	956	PS50273	Ca2+/Na+ channel

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 6 28 NFDSLLWAIVTVFQILTQEDWNK

44 66 YFIALMTFGNYVLFNLLVAILVE

378 399 KMFDHVVLVIIFLNCITIAMER

414 436 LSNYIFTAVFLAEMTVKVVALGW

455 477 LVLISVIDILVSMVSDSGTKILG

516 537 NIVVICCAFFIIFGILGVQLFK

573 595 NLGQALMSLFVLASKDGWVDIMY

617 639 LYFISFLLIVAFFVLNMFVGVVV

714 736 YLDLFITGVIGLNVVTMAMEHYQ

746 768 KICNYIFTVIFVLESVFKLVAFG

776 798 RWNQLDLAIVLLSIMGITLEEIE

811 833 RIMRVLRIARVLKLLKMAVGMRA

847 869 NLGLLFMLLFFIFAALGVELFGD

928 950 ISPIYFVSFVLTAQFVLVNVVIA

Method	From	To	amino acid sequence
SOSUI	6	28	NFDSLLWAIVTVFQILTQEDWNK
44	66	YFIALMTFGNYVLFNLLVAILVE
378	399	KMFDHVVLVIIFLNCITIAMER
414	436	LSNYIFTAVFLAEMTVKVVALGW
455	477	LVLISVIDILVSMVSDSGTKILG
516	537	NIVVICCAFFIIFGILGVQLFK
573	595	NLGQALMSLFVLASKDGWVDIMY
617	639	LYFISFLLIVAFFVLNMFVGVVV
714	736	YLDLFITGVIGLNVVTMAMEHYQ
746	768	KICNYIFTVIFVLESVFKLVAFG
776	798	RWNQLDLAIVLLSIMGITLEEIE
811	833	RIMRVLRIARVLKLLKMAVGMRA
847	869	NLGLLFMLLFFIFAALGVELFGD
928	950	ISPIYFVSFVLTAQFVLVNVVIA

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	772 bp
Genome contig ID	gi65527427r_94129459
PolyA signal sequence (AATAAA,-33)	+--------+--------+----*----+---- AAAATAAAAAGTTAATTACAGTCCAGAGTAAAAGC
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AAAGGGGATGCAGAGATAGGCGTGTTTAGAGGCCTGGAGAAAGGAAGTGG

Gene/Protein Characteristic Table for mKIAA1123

Features of the cloned DNA sequence

Features of the protein sequence