ROUGE

Gene/Protein Characteristic Table for mKIAA0422

Link to : HUGE \| InGAP \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK122279
Description :	Adenylate cyclase, type VI.
Clone Name :	mbh03531 [Vector Info]
Source :	Mouse brain

Features of the cloned DNA sequence	Description

Length: 3963 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 2358 bp

Genome contig ID gi65543215r_98548238
PolyA signal sequence
(AATAAA,-22)
+----*----+----*----+----*----+----
ATATTTAAATATCAATAAAATCAAACTCTTTGTAT
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AAAAAAAAAAAAAAGAAAAGCCCTGTTCTCTGCAGCTGTTTGGGTGCAGG

Genomic structure deduced by Blast search against draft genome sequences
Comparison with the corresponding KIAA cDNA.

KIAA Alignment based on:

KIAA0422 DNA sequence, AA sequence, Physical map

KIAA	Alignment based on:
KIAA0422	DNA sequence, AA sequence, Physical map

Features of the protein sequence	Description

Coding region: 430..1605
Length: 391 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
Q01341	8.5e-150	97.5	Adenylate cycla...	Mus musculus
EDL04180	8.5e-150	97.5	adenylate cycla...	Mus musculus
AAI56961	8.5e-150	97.5	Adenylate cycla...	synthetic construct
EDL87050	2.2e-147	95.6	adenylate cycla...	Rattus norvegicus
Q03343	2.2e-147	95.6	Adenylate cycla...	Rattus norvegicus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AK220469	3.5e-62	46.4	mKIAA4070
AK122432	8.2e-61	47.3	mKIAA1060
U30602	1.1e-37	37.0	mKIAA0520
AK122298	9.8e-31	42.5	mKIAA0511
AF297083	2.2e-15	30.2	mKIAA4084

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR001054 193 387 PF00211 Adenylyl cyclase class-3/4/guanylyl cyclase

HMMSmart IPR001054 162 370 SM00044 Adenylyl cyclase class-3/4/guanylyl cyclase

ProfileScan IPR001054 202 341 PS50125 Adenylyl cyclase class-3/4/guanylyl cyclase

ScanRegExp IPR001054 318 341 PS00452 Adenylyl cyclase class-3/4/guanylyl cyclase

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR001054	193	387	PF00211	Adenylyl cyclase class-3/4/guanylyl cyclase
HMMSmart	IPR001054	162	370	SM00044	Adenylyl cyclase class-3/4/guanylyl cyclase
ProfileScan	IPR001054	202	341	PS50125	Adenylyl cyclase class-3/4/guanylyl cyclase
ScanRegExp	IPR001054	318	341	PS00452	Adenylyl cyclase class-3/4/guanylyl cyclase

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 11 33 GSRALPALHALVFAVTQRCLCCP

37 59 QYFVGNVLLSLLASSVFLHISSI

63 85 AMTFILGFTYLVLLLLGPPAAIF

117 139 LKYMTPVILLVFALALYLHAQQV

Method	From	To	amino acid sequence
SOSUI	11	33	GSRALPALHALVFAVTQRCLCCP
37	59	QYFVGNVLLSLLASSVFLHISSI
63	85	AMTFILGFTYLVLLLLGPPAAIF
117	139	LKYMTPVILLVFALALYLHAQQV

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	YES

Length of 3'UTR	2358 bp
Genome contig ID	gi65543215r_98548238
PolyA signal sequence (AATAAA,-22)	+--------+--------+----*----+---- ATATTTAAATATCAATAAAATCAAACTCTTTGTAT
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AAAAAAAAAAAAAAGAAAAGCCCTGTTCTCTGCAGCTGTTTGGGTGCAGG

Gene/Protein Characteristic Table for mKIAA0422

Features of the cloned DNA sequence

Features of the protein sequence