ROUGE

Gene/Protein Characteristic Table for mKIAA0294

Link to : HUGE \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK220332
Description :	Rho guanine nucleotide exchange factor 10.
Clone Name :	mbg02039 [Vector Info]
Source :	Mouse brain

Features of the cloned DNA sequence	Description

Length: 4697 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 616 bp

Genome contig ID gi65515060f_14203532
PolyA signal sequence
(ATTAAA,-25)
+----*----+----*----+----*----+----
ATTTTTTTCTATTAAAAATCAACAGTTAACATTTT
Flanking genome sequence
(175399 - 175448)
----+----*----+----*----+----*----+----*----+----*
AGTCAATGTACTCTCTGTAGCATTTCACACATAATCTTTACTTGAAGCCA

Genomic structure deduced by Blast search against draft genome sequences
Comparison with the corresponding KIAA cDNA.

KIAA Alignment based on:

KIAA0294 DNA sequence, AA sequence, Physical map

KIAA	Alignment based on:
KIAA0294	DNA sequence, AA sequence, Physical map

Features of the protein sequence	Description

Coding region: 107..4078
Length: 1324 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
NP_001032825	99.8	Rho guanine nuc...	Mus musculus
AAH59212	99.8	Arhgef10 protei...	Mus musculus
AAI12927	80.6	ARHGEF10 protei...	Homo sapiens
EDL22194	97.0	Rho guanine nuc...	Mus musculus
EDL22195	97.0	Rho guanine nuc...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AK129408	1.5e-129	42.8	mKIAA1626
AK122250	2.3e-18	23.1	mKIAA0337
AK220452	2.8e-13	30.0	mKIAA4037
AB093282	9e-10	29.0	mKIAA1066
AK172961	9.4e-10	24.1	mKIAA0516

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR000219 380 562 PF00621 DH

HMMSmart IPR000219 380 562 SM00325 DH

ProfileScan IPR000219 376 563 PS50010 DH

ScanRegExp IPR000169 1125 1135 PS00639 Peptidase

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR000219	380	562	PF00621	DH
HMMSmart	IPR000219	380	562	SM00325	DH
ProfileScan	IPR000219	376	563	PS50010	DH
ScanRegExp	IPR000169	1125	1135	PS00639	Peptidase

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 1024 1046 LPVRSLLLVEGALWAASGGQVFM

1064 1086 EGMVISHMAVAGVGIWIAFTSGS

1121 1143 TSLLVCHGLLMVGTSLGVVVALP

Method	From	To	amino acid sequence
SOSUI	1024	1046	LPVRSLLLVEGALWAASGGQVFM
1064	1086	EGMVISHMAVAGVGIWIAFTSGS
1121	1143	TSLLVCHGLLMVGTSLGVVVALP

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	YES

Length of 3'UTR	616 bp
Genome contig ID	gi65515060f_14203532
PolyA signal sequence (ATTAAA,-25)	+--------+--------+----*----+---- ATTTTTTTCTATTAAAAATCAACAGTTAACATTTT
Flanking genome sequence (175399 - 175448)	----+--------+--------+--------+--------+----* AGTCAATGTACTCTCTGTAGCATTTCACACATAATCTTTACTTGAAGCCA

Gene/Protein Characteristic Table for mKIAA0294

Features of the cloned DNA sequence

Features of the protein sequence