ROUGE

Gene/Protein Characteristic Table for mKIAA0046

Link to : HUGE \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK220319
Description :	Chloride channel protein 6.
Clone Name :	mkg00303 [Vector Info]
Source :	Mouse adult kidney

Features of the cloned DNA sequence	Description

Length: 3289 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 1186 bp

Genome contig ID gi65493515r_146396628
PolyA signal sequence
(AATAAA,-20)
+----*----+----*----+----*----+----
TCACTCTTAAGTCAGAATAAAATGTCTGCACCTTC
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
TCTGTAGACCTTGTCTCCACGGTGCTCGCTCGCTCTTAAGTAGGGAAAGT

Genomic structure deduced by Blast search against draft genome sequences
Comparison with the corresponding KIAA cDNA.

KIAA Alignment based on:

KIAA0046 DNA sequence, AA sequence, Physical map

KIAA	Alignment based on:
KIAA0046	DNA sequence, AA sequence, Physical map

Features of the protein sequence	Description

Coding region: 3..596, 607..2103
Length: 696 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
O35454	7.4e-201	92.1	Chloride channe...	Mus musculus
CAM14892	7.5e-201	91.9	chloride channe...	Mus musculus
EDL81090	2.1e-198	90.6	rCG30856 [Rattu...	Rattus norvegicus
XP_001104721	1.4e-194	88.7	chloride channe...	Macaca mulatta
EAW71712	1.8e-194	86.2	chloride channe...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output)
No significant homologues
Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR001807 37 54 PR00762 Cl- channel

IPR001807 68 87 PR00762 Cl- channel

IPR001807 132 151 PR00762 Cl- channel

IPR001807 311 331 PR00762 Cl- channel

IPR001807 346 362 PR00762 Cl- channel

IPR001807 364 383 PR00762 Cl- channel

IPR001807 402 416 PR00762 Cl- channel

HMMPfam IPR001807 21 399 PF00654 Cl- channel

IPR000644 430 685 PF00571 CBS

HMMSmart IPR000644 435 484 SM00116 CBS

IPR000644 637 685 SM00116 CBS

ProfileScan IPR000644 637 684 PS50147 CBS

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR001807	37	54	PR00762	Cl- channel
IPR001807	68	87	PR00762	Cl- channel
IPR001807	132	151	PR00762	Cl- channel
IPR001807	311	331	PR00762	Cl- channel
IPR001807	346	362	PR00762	Cl- channel
IPR001807	364	383	PR00762	Cl- channel
IPR001807	402	416	PR00762	Cl- channel
HMMPfam	IPR001807	21	399	PF00654	Cl- channel
IPR000644	430	685	PF00571	CBS
HMMSmart	IPR000644	435	484	SM00116	CBS
IPR000644	637	685	SM00116	CBS
ProfileScan	IPR000644	637	684	PS50147	CBS

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 12 34 ALSLLELLGFNLTFVFLASLLVL

57 79 PGIVRLRTLLCKVFGVLFSVSGG

127 149 VSAGAAAGVAAAFGAPIGGTLFS

157 179 WNQGLTWKVLFCSMSATFTLNFF

198 220 NLRVLESLLVSLVTTVVVFVASM

286 308 TFSPVTLALFFILYFLLACWTFG

316 338 FVPSLLCGAAFGRLVANVLKSYI

348 370 FALIGAAAFLGGVVRMTISLTVI

380 402 YGLPIMVTLMVAKWTGDLFNKGI

Method	From	To	amino acid sequence
SOSUI	12	34	ALSLLELLGFNLTFVFLASLLVL
57	79	PGIVRLRTLLCKVFGVLFSVSGG
127	149	VSAGAAAGVAAAFGAPIGGTLFS
157	179	WNQGLTWKVLFCSMSATFTLNFF
198	220	NLRVLESLLVSLVTTVVVFVASM
286	308	TFSPVTLALFFILYFLLACWTFG
316	338	FVPSLLCGAAFGRLVANVLKSYI
348	370	FALIGAAAFLGGVVRMTISLTVI
380	402	YGLPIMVTLMVAKWTGDLFNKGI

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	YES

Length of 3'UTR	1186 bp
Genome contig ID	gi65493515r_146396628
PolyA signal sequence (AATAAA,-20)	+--------+--------+----*----+---- TCACTCTTAAGTCAGAATAAAATGTCTGCACCTTC
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* TCTGTAGACCTTGTCTCCACGGTGCTCGCTCGCTCTTAAGTAGGGAAAGT

Gene/Protein Characteristic Table for mKIAA0046

Features of the cloned DNA sequence

Features of the protein sequence