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SpecieshumanProduct IDFXC12466Cloning SiteSgfI-PmeIGenBank AccessionGeneKIBB9019SymbolACACB
Alias : ACC-beta, ACC2, ACCB, HACC275Descriptionacetyl-CoA carboxylase betaOriginal Clone IDoc01543
Length: 7374 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 2458 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS31898.1 0 100.0 ACACB CCDS11317.1 0 75.2 ACACA CCDS42302.1 0 75.2 ACACA CCDS11318.1 0 76.5 ACACA CCDS42303.1 0 76.5 ACACA
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR005481 260 379 PF00289 Carbamoyl-phosphate synthase IPR005479 431 614 PF02786 Carbamoyl-phosphate synthetase IPR005482 651 757 PF02785 Biotin carboxylase IPR000089 897 961 PF00364 Biotin/lipoyl attachment IPR013537 962 1688 PF08326 Acetyl-CoA carboxylase IPR000022 1780 2333 PF01039 Carboxyl transferase HMMSmart IPR005482 650 757 SM00878 Biotin carboxylase ProfileScan IPR011764 259 761 PS50979 Biotin carboxylation domain IPR011761 414 609 PS50975 ATP-grasp fold IPR000089 895 961 PS50968 Biotin/lipoyl attachment IPR011762 1809 1989 PS50980 Acetyl-coenzyme A carboxyltransferase IPR011763 1990 2305 PS50989 Acetyl-coenzyme A carboxyltransferase
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 2 VLLLCLSCLIFSCLTFSWLKIW 23 PRIMARY 22
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) XP_011536561 2458 601557 100.0 100.0 NP_001084 2458 601557 100.0 100.0 XP_005253933 2458 601557 100.0 100.0 XP_011536566 2249 601557 100.0 91.2 XP_006719430 2256 601557 99.9 91.2 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB9019 Download>KIBB9019 7374 bp ATGGTCTTGCTTCTTTGTCTATCTTGTCTGATTTTCTCCTGTCTGACCTTTTCCTGGTTA AAAATCTGGGGGAAAATGACGGACTCCAAGCCGATCACCAAGAGTAAATCAGAAGCAAAC CTCATCCCGAGCCAGGAGCCCTTTCCAGCCTCTGATAACTCAGGGGAGACACCGCAGAGA AATGGGGAGGGCCACACTCTGCCCAAGACACCCAGCCAGGCCGAGCCAGCCTCCCACAAA GGCCCCAAAGATGCCGGTCGGCGGAGAAACTCCCTACCACCCTCCCACCAGAAGCCCCCA AGAAACCCCCTTTCTTCCAGTGACGCAGCACCCTCCCCAGAGCTTCAAGCCAACGGGACT GGGACACAAGGTCTGGAGGCCACAGATACCAATGGCCTGTCCTCCTCAGCCAGGCCCCAG GGCCAGCAAGCTGGCTCCCCCTCCAAAGAAGACAAGAAGCAGGCAAACATCAAGAGGCAG CTGATGACCAACTTCATCCTGGGCTCTTTTGATGACTACTCCTCCGACGAGGACTCTGTT GCTGGCTCATCTCGTGAGTCTACCCGGAAGGGCAGCCGGGCCAGCTTGGGGGCCCTGTCC CTGGAGGCTTATCTGACCACAGGTGAAGCTGAGACCCGCGTCCCCACTATGAGGCCGAGC ATGTCGGGACTCCACCTGGTGAAGAGGGGACGGGAACACAAGAAGCTGGACCTGCACAGA GACTTTACCGTGGCTTCTCCCGCTGAGTTTGTCACACGCTTTGGGGGGGATCGGGTCATC GAGAAGGTGCTTATTGCCAACAACGGGATTGCCGCCGTGAAGTGCATGCGCTCCATCCGC AGGTGGGCCTATGAGATGTTCCGCAACGAGCGGGCCATCCGGTTTGTTGTGATGGTGACC CCCGAGGACCTTAAGGCCAACGCAGAGTACATCAAGATGGCGGATCATTACGTCCCCGTC CCAGGAGGGCCCAATAACAACAACTATGCCAACGTGGAGCTGATTGTGGACATTGCCAAG AGAATCCCCGTGCAGGCGGTGTGGGCTGGCTGGGGCCATGCTTCAGAAAACCCTAAACTT CCGGAGCTGCTGTGCAAGAATGGAGTTGCTTTCTTAGGCCCTCCCAGTGAGGCCATGTGG GCCTTAGGAGATAAGATCGCCTCCACCGTTGTCGCCCAGACGCTACAGGTCCCAACCCTG CCCTGGAGTGGAAGCGGCCTGACAGTGGAGTGGACAGAAGATGATCTGCAGCAGGGAAAA AGAATCAGTGTCCCAGAAGATGTTTATGACAAGGGTTGCGTGAAAGACGTAGATGAGGGC TTGGAGGCAGCAGAAAGAATTGGTTTTCCATTGATGATCAAAGCTTCTGAAGGTGGCGGA GGGAAGGGAATCCGGAAGGCTGAGAGTGCGGAGGACTTCCCGATCCTTTTCAGACAAGTA CAGAGTGAGATCCCAGGCTCGCCCATCTTTCTCATGAAGCTGGCCCAGCACGCCCGTCAC CTGGAAGTTCAGATCCTCGCTGACCAGTATGGGAATGCTGTGTCTCTGTTTGGTCGCGAC TGCTCCATCCAGCGGCGGCATCAGAAGATCGTTGAGGAAGCACCGGCCACCATCGCCCCG CTGGCCATATTCGAGTTCATGGAGCAGTGTGCCATCCGCCTGGCCAAGACCGTGGGCTAT GTGAGTGCAGGGACAGTGGAATACCTCTATAGTCAGGATGGCAGCTTCCACTTCTTGGAG CTGAATCCTCGCTTGCAGGTGGAACATCCCTGCACAGAAATGATTGCTGATGTTAATCTG CCGGCCGCCCAGCTACAGATCGCCATGGGCGTGCCACTGCACCGGCTGAAGGATATCCGG CTTCTGTATGGAGAGTCACCATGGGGAGTGACTCCCATTTCTTTTGAAACCCCCTCAAAC CCTCCCCTCGCCCGAGGCCACGTCATTGCCGCCAGAATCACCAGCGAAAACCCAGACGAG GGTTTTAAGCCGAGCTCCGGGACTGTCCAGGAACTGAATTTCCGGAGCAGCAAGAACGTG TGGGGTTACTTCAGCGTGGCCGCTACTGGAGGCCTGCACGAGTTTGCGGATTCCCAATTT GGGCACTGCTTCTCCTGGGGAGAGAACCGGGAAGAGGCCATTTCGAACATGGTGGTGGCT TTGAAGGAACTGTCCATCCGAGGCGACTTTAGGACTACCGTGGAATACCTCATTAACCTC CTGGAGACCGAGAGCTTCCAGAACAACGACATCGACACCGGGTGGTTGGACTACCTCATT GCTGAGAAAGTGCAGGCGGAGAAACCGGATATCATGCTTGGGGTGGTATGCGGGGCCTTG AACGTGGCCGATGCGATGTTCAGAACGTGCATGACAGATTTCTTACACTCCCTGGAAAGG GGCCAGGTCCTCCCAGCGGATTCACTACTGAACCTCGTAGATGTGGAATTAATTTACGGA GGTGTTAAGTACATTCTCAAGGTGGCCCGGCAGTCTCTGACCATGTTCGTTCTCATCATG AATGGCTGCCACATCGAGATTGATGCCCACCGGCTGAATGATGGGGGGCTCCTGCTCTCC TACAATGGGAACAGCTACACCACCTACATGAAGGAAGAGGTTGACAGTTACCGAATTACC ATCGGCAATAAGACGTGTGTGTTTGAGAAGGAGAACGATCCTACAGTCCTGAGATCCCCC TCGGCTGGGAAGCTGACACAGTACACAGTGGAGGATGGGGGCCACGTTGAGGCTGGGAGC AGCTACGCTGAGATGGAGGTGATGAAGATGATCATGACCCTGAACGTTCAGGAAAGAGGC CGGGTGAAGTACATCAAGCGTCCAGGTGCCGTGCTGGAAGCAGGCTGCGTGGTGGCCAGG CTGGAGCTCGATGACCCTTCTAAAGTCCACCCGGCTGAACCGTTCACAGGAGAACTCCCT GCCCAGCAGACACTGCCCATCCTCGGAGAGAAACTGCACCAGGTCTTCCACAGCGTCCTG GAAAACCTCACCAACGTCATGAGTGGCTTTTGTCTGCCAGAGCCCGTTTTTAGCATAAAG CTGAAGGAGTGGGTGCAGAAGCTCATGATGACCCTCCGGCACCCGTCACTGCCGCTGCTG GAGCTGCAGGAGATCATGACCAGCGTGGCAGGCCGCATCCCCGCCCCTGTGGAGAAGTCT GTCCGCAGGGTGATGGCCCAGTATGCCAGCAACATCACCTCGGTGCTGTGCCAGTTCCCC AGCCAGCAGATAGCCACCATCCTGGACTGCCATGCAGCCACCCTGCAGCGGAAGGCTGAT CGAGAGGTCTTCTTCATCAACACCCAGAGCATCGTGCAGTTGGTCCAGAGATACCGCAGC GGGATCCGCGGCTATATGAAAACAGTGGTGTTGGATCTCCTGAGAAGATACTTGCGTGTT GAGCACCATTTTCAGCAAGCCCACTACGACAAGTGTGTGATAAACCTCAGGGAGCAGTTC AAGCCAGACATGTCCCAGGTGCTGGACTGCATCTTCTCCCACGCACAGGTGGCCAAGAAG AACCAGCTGGTGATCATGTTGATCGATGAGCTGTGTGGCCCAGACCCTTCCCTGTCGGAC GAGCTGATCTCCATCCTCAACGAGCTCACTCAGCTGAGCAAAAGCGAGCACTGCAAAGTG GCCCTCAGAGCCCGGCAGATCCTGATTGCCTCCCACCTCCCCTCCTACGAGCTGCGGCAT AACCAGGTGGAGTCCATTTTCCTGTCTGCCATTGACATGTACGGCCACCAGTTCTGCCCC GAGAACCTCAAGAAATTAATACTTTCGGAAACAACCATCTTCGACGTCCTGCCTACTTTC TTCTATCACGCAAACAAAGTCGTGTGCATGGCGTCCTTGGAGGTTTACGTGCGGAGGGGC TACATCGCCTATGAGTTAAACAGCCTGCAGCACCGGCAGCTCCCGGACGGCACCTGCGTG GTAGAATTCCAGTTCATGCTGCCGTCCTCCCACCCAAACCGGATGACCGTGCCCATCAGC ATCACCAACCCTGACCTGCTGAGGCACAGCACAGAGCTCTTCATGGACAGCGGCTTCTCC CCACTGTGCCAGCGCATGGGAGCCATGGTAGCCTTCAGGAGATTCGAGGACTTCACCAGA AATTTTGATGAAGTCATCTCTTGCTTCGCCAACGTGCCCAAAGACACCCCCCTCTTCAGC GAGGCCCGCACCTCCCTATACTCCGAGGATGACTGCAAGAGCCTCAGAGAAGAGCCCATC CACATTCTGAATGTGTCCATCCAGTGTGCAGACCACCTGGAGGATGAGGCACTGGTGCCG ATTTTACGGACATTCGTACAGTCCAAGAAAAATATCCTTGTGGATTATGGACTCCGACGA ATCACATTCTTGATTGCCCAAGAGAAAGAATTTCCCAAGTTTTTCACATTCAGAGCAAGA GATGAGTTTGCAGAAGATCGCATTTACCGTCACTTGGAACCTGCCCTGGCCTTCCAGCTG GAACTTAACCGGATGCGTAACTTCGATCTGACCGCCGTGCCCTGTGCCAACCACAAGATG CACCTTTACCTGGGTGCTGCCAAGGTGAAGGAAGGTGTGGAAGTGACGGACCATAGGTTC TTCATCCGCGCCATCATCAGGCACTCTGACCTGATCACAAAGGAAGCCTCCTTCGAATAC CTGCAGAACGAGGGTGAGCGGCTGCTCCTGGAGGCCATGGACGAGCTGGAGGTGGCGTTC AATAACACCAGCGTGCGCACCGACTGCAACCACATCTTCCTCAACTTCGTGCCCACTGTC ATCATGGACCCCTTCAAGATCGAGGAGTCCGTGCGCTACATGGTTATGCGCTACGGCAGC CGGCTGTGGAAACTCCGTGTGCTACAGGCTGAGGTCAAGATCAACATCCGCCAGACCACC ACCGGCAGTGCCGTTCCCATCCGCCTGTTCATCACCAATGAGTCGGGCTACTACCTGGAC ATCAGCCTCTACAAAGAAGTGACTGACTCCAGATCTGGAAATATCATGTTTCACTCCTTC GGCAACAAGCAAGGGCCCCAGCACGGGATGCTGATCAATACTCCCTACGTCACCAAGGAT CTGCTCCAGGCCAAGCGATTCCAGGCCCAGACCCTGGGAACCACCTACATCTATGACTTC CCGGAAATGTTCAGGCAGGCTCTCTTTAAACTGTGGGGCTCCCCAGACAAGTATCCCAAA GACATCCTGACATACACTGAATTAGTGTTGGACTCTCAGGGCCAGCTGGTGGAGATGAAC CGACTTCCTGGTGGAAATGAGGTGGGCATGGTGGCCTTCAAAATGAGGTTTAAGACCCAG GAGTACCCGGAAGGACGGGATGTGATCGTCATCGGCAATGACATCACCTTTCGCATTGGA TCCTTTGGCCCTGGAGAGGACCTTCTGTACCTGCGGGCATCCGAGATGGCCCGGGCAGAG GGCATTCCCAAAATTTACGTGGCAGCCAACAGTGGCGCCCGTATTGGCATGGCAGAGGAG ATCAAACACATGTTCCACGTGGCTTGGGTGGACCCAGAAGACCCCCACAAAGGATTTAAA TACCTGTACCTGACTCCCCAAGACTACACCAGAATCAGCTCCCTGAACTCCGTCCACTGT AAACACATCGAGGAAGGAGGAGAGTCCAGATACATGATCACGGATATCATCGGGAAGGAT GATGGCTTGGGCGTGGAGAATCTGAGGGGCTCAGGCATGATTGCTGGGGAGTCCTCTCTG GCTTACGAAGAGATCGTCACCATTAGCTTGGTGACCTGCCGAGCCATTGGGATTGGGGCC TACTTGGTGAGGCTGGGCCAGCGAGTGATCCAGGTGGAGAATTCCCACATCATCCTCACA GGAGCAAGTGCTCTCAACAAGGTCCTGGGAAGAGAGGTCTACACATCCAACAACCAGCTG GGTGGCGTTCAGATCATGCATTACAATGGTGTCTCCCACATCACCGTGCCAGATGACTTT GAGGGGGTTTATACCATCCTGGAGTGGCTGTCCTATATGCCAAAGGATAATCACAGCCCT GTCCCTATCATCACACCCACTGACCCCATTGACAGAGAAATTGAATTCCTCCCATCCAGA GCTCCCTACGACCCCCGGTGGATGCTTGCAGGAAGGCCTCACCCAACTCTGAAGGGAACG TGGCAGAGCGGATTCTTTGACCACGGCAGTTTCAAGGAAATCATGGCACCCTGGGCGCAG ACCGTGGTGACAGGACGAGCAAGGCTTGGGGGGATTCCCGTGGGAGTGATTGCTGTGGAG ACACGGACTGTGGAGGTGGCAGTCCCTGCAGACCCTGCCAACCTGGATTCTGAGGCCAAG ATAATTCAGCAGGCAGGACAGGTGTGGTTCCCAGACTCAGCCTACAAAACCGCCCAGGCC GTCAAGGACTTCAACCGGGAGAAGTTGCCCCTGATGATCTTTGCCAACTGGAGGGGGTTC TCCGGTGGCATGAAAGACATGTATGACCAGGTGCTGAAGTTTGGAGCCTACATCGTGGAC GGCCTTAGACAATACAAACAGCCCATCCTGATCTATATCCCGCCCTATGCGGAGCTCCGG GGAGGCTCCTGGGTGGTCATAGATGCCACCATCAACCCGCTGTGCATAGAAATGTATGCA GACAAAGAGAGCAGGGGTGGTGTTCTGGAACCAGAGGGGACAGTGGAGATTAAGTTCCGA AAGAAAGATCTGATAAAGTCCATGAGAAGGATCGATCCAGCTTACAAGAAGCTCATGGAA CAGCTAGGGGAACCTGATCTCTCCGACAAGGACCGAAAGGACCTGGAGGGCCGGCTAAAG GCTCGCGAGGACCTGCTGCTCCCCATCTACCACCAGGTGGCGGTGCAGTTCGCCGACTTC CATGACACACCCGGCCGGATGCTGGAGAAGGGCGTCATATCTGACATCCTGGAGTGGAAG ACCGCACGCACCTTCCTGTATTGGCGTCTGCGCCGCCTCCTCCTGGAGGACCAGGTCAAG CAGGAGATCCTGCAGGCCAGCGGGGAGCTGAGTCACGTGCATATCCAGTCCATGCTGCGT CGCTGGTTCGTGGAGACGGAGGGGGCTGTCAAGGCCTACTTGTGGGACAACAACCAGGTG GTTGTGCAGTGGCTGGAACAGCACTGGCAGGCAGGGGATGGCCCGCGCTCCACCATCCGT GAGAACATCACGTACCTGAAGCACGACTCTGTCCTCAAGACCATCCGAGGCCTGGTTGAA GAAAACCCCGAGGTGGCCGTGGACTGTGTGATATACCTGAGCCAGCACATCAGCCCAGCT GAGCGGGCGCAGGTCGTTCACCTGCTGTCTACCATGGACAGCCCGGCCTCCACC
Cloned ORF protein sequence for pF1KB9019 Download>KIBB9019 2458 aa MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST
Nucleotide Sequence (with vector) for pF1KB9019 Download>pF1KB9019 10487 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGGTCTTGCTT CTTTGTCTATCTTGTCTGATTTTCTCCTGTCTGACCTTTTCCTGGTTAAAAATCTGGGGG AAAATGACGGACTCCAAGCCGATCACCAAGAGTAAATCAGAAGCAAACCTCATCCCGAGC CAGGAGCCCTTTCCAGCCTCTGATAACTCAGGGGAGACACCGCAGAGAAATGGGGAGGGC CACACTCTGCCCAAGACACCCAGCCAGGCCGAGCCAGCCTCCCACAAAGGCCCCAAAGAT GCCGGTCGGCGGAGAAACTCCCTACCACCCTCCCACCAGAAGCCCCCAAGAAACCCCCTT TCTTCCAGTGACGCAGCACCCTCCCCAGAGCTTCAAGCCAACGGGACTGGGACACAAGGT CTGGAGGCCACAGATACCAATGGCCTGTCCTCCTCAGCCAGGCCCCAGGGCCAGCAAGCT GGCTCCCCCTCCAAAGAAGACAAGAAGCAGGCAAACATCAAGAGGCAGCTGATGACCAAC TTCATCCTGGGCTCTTTTGATGACTACTCCTCCGACGAGGACTCTGTTGCTGGCTCATCT CGTGAGTCTACCCGGAAGGGCAGCCGGGCCAGCTTGGGGGCCCTGTCCCTGGAGGCTTAT CTGACCACAGGTGAAGCTGAGACCCGCGTCCCCACTATGAGGCCGAGCATGTCGGGACTC CACCTGGTGAAGAGGGGACGGGAACACAAGAAGCTGGACCTGCACAGAGACTTTACCGTG GCTTCTCCCGCTGAGTTTGTCACACGCTTTGGGGGGGATCGGGTCATCGAGAAGGTGCTT ATTGCCAACAACGGGATTGCCGCCGTGAAGTGCATGCGCTCCATCCGCAGGTGGGCCTAT GAGATGTTCCGCAACGAGCGGGCCATCCGGTTTGTTGTGATGGTGACCCCCGAGGACCTT AAGGCCAACGCAGAGTACATCAAGATGGCGGATCATTACGTCCCCGTCCCAGGAGGGCCC AATAACAACAACTATGCCAACGTGGAGCTGATTGTGGACATTGCCAAGAGAATCCCCGTG CAGGCGGTGTGGGCTGGCTGGGGCCATGCTTCAGAAAACCCTAAACTTCCGGAGCTGCTG TGCAAGAATGGAGTTGCTTTCTTAGGCCCTCCCAGTGAGGCCATGTGGGCCTTAGGAGAT AAGATCGCCTCCACCGTTGTCGCCCAGACGCTACAGGTCCCAACCCTGCCCTGGAGTGGA AGCGGCCTGACAGTGGAGTGGACAGAAGATGATCTGCAGCAGGGAAAAAGAATCAGTGTC CCAGAAGATGTTTATGACAAGGGTTGCGTGAAAGACGTAGATGAGGGCTTGGAGGCAGCA GAAAGAATTGGTTTTCCATTGATGATCAAAGCTTCTGAAGGTGGCGGAGGGAAGGGAATC CGGAAGGCTGAGAGTGCGGAGGACTTCCCGATCCTTTTCAGACAAGTACAGAGTGAGATC CCAGGCTCGCCCATCTTTCTCATGAAGCTGGCCCAGCACGCCCGTCACCTGGAAGTTCAG ATCCTCGCTGACCAGTATGGGAATGCTGTGTCTCTGTTTGGTCGCGACTGCTCCATCCAG CGGCGGCATCAGAAGATCGTTGAGGAAGCACCGGCCACCATCGCCCCGCTGGCCATATTC GAGTTCATGGAGCAGTGTGCCATCCGCCTGGCCAAGACCGTGGGCTATGTGAGTGCAGGG ACAGTGGAATACCTCTATAGTCAGGATGGCAGCTTCCACTTCTTGGAGCTGAATCCTCGC TTGCAGGTGGAACATCCCTGCACAGAAATGATTGCTGATGTTAATCTGCCGGCCGCCCAG CTACAGATCGCCATGGGCGTGCCACTGCACCGGCTGAAGGATATCCGGCTTCTGTATGGA GAGTCACCATGGGGAGTGACTCCCATTTCTTTTGAAACCCCCTCAAACCCTCCCCTCGCC CGAGGCCACGTCATTGCCGCCAGAATCACCAGCGAAAACCCAGACGAGGGTTTTAAGCCG AGCTCCGGGACTGTCCAGGAACTGAATTTCCGGAGCAGCAAGAACGTGTGGGGTTACTTC AGCGTGGCCGCTACTGGAGGCCTGCACGAGTTTGCGGATTCCCAATTTGGGCACTGCTTC TCCTGGGGAGAGAACCGGGAAGAGGCCATTTCGAACATGGTGGTGGCTTTGAAGGAACTG TCCATCCGAGGCGACTTTAGGACTACCGTGGAATACCTCATTAACCTCCTGGAGACCGAG AGCTTCCAGAACAACGACATCGACACCGGGTGGTTGGACTACCTCATTGCTGAGAAAGTG CAGGCGGAGAAACCGGATATCATGCTTGGGGTGGTATGCGGGGCCTTGAACGTGGCCGAT GCGATGTTCAGAACGTGCATGACAGATTTCTTACACTCCCTGGAAAGGGGCCAGGTCCTC CCAGCGGATTCACTACTGAACCTCGTAGATGTGGAATTAATTTACGGAGGTGTTAAGTAC ATTCTCAAGGTGGCCCGGCAGTCTCTGACCATGTTCGTTCTCATCATGAATGGCTGCCAC ATCGAGATTGATGCCCACCGGCTGAATGATGGGGGGCTCCTGCTCTCCTACAATGGGAAC AGCTACACCACCTACATGAAGGAAGAGGTTGACAGTTACCGAATTACCATCGGCAATAAG ACGTGTGTGTTTGAGAAGGAGAACGATCCTACAGTCCTGAGATCCCCCTCGGCTGGGAAG CTGACACAGTACACAGTGGAGGATGGGGGCCACGTTGAGGCTGGGAGCAGCTACGCTGAG ATGGAGGTGATGAAGATGATCATGACCCTGAACGTTCAGGAAAGAGGCCGGGTGAAGTAC ATCAAGCGTCCAGGTGCCGTGCTGGAAGCAGGCTGCGTGGTGGCCAGGCTGGAGCTCGAT GACCCTTCTAAAGTCCACCCGGCTGAACCGTTCACAGGAGAACTCCCTGCCCAGCAGACA CTGCCCATCCTCGGAGAGAAACTGCACCAGGTCTTCCACAGCGTCCTGGAAAACCTCACC AACGTCATGAGTGGCTTTTGTCTGCCAGAGCCCGTTTTTAGCATAAAGCTGAAGGAGTGG GTGCAGAAGCTCATGATGACCCTCCGGCACCCGTCACTGCCGCTGCTGGAGCTGCAGGAG ATCATGACCAGCGTGGCAGGCCGCATCCCCGCCCCTGTGGAGAAGTCTGTCCGCAGGGTG ATGGCCCAGTATGCCAGCAACATCACCTCGGTGCTGTGCCAGTTCCCCAGCCAGCAGATA GCCACCATCCTGGACTGCCATGCAGCCACCCTGCAGCGGAAGGCTGATCGAGAGGTCTTC TTCATCAACACCCAGAGCATCGTGCAGTTGGTCCAGAGATACCGCAGCGGGATCCGCGGC TATATGAAAACAGTGGTGTTGGATCTCCTGAGAAGATACTTGCGTGTTGAGCACCATTTT CAGCAAGCCCACTACGACAAGTGTGTGATAAACCTCAGGGAGCAGTTCAAGCCAGACATG TCCCAGGTGCTGGACTGCATCTTCTCCCACGCACAGGTGGCCAAGAAGAACCAGCTGGTG ATCATGTTGATCGATGAGCTGTGTGGCCCAGACCCTTCCCTGTCGGACGAGCTGATCTCC ATCCTCAACGAGCTCACTCAGCTGAGCAAAAGCGAGCACTGCAAAGTGGCCCTCAGAGCC CGGCAGATCCTGATTGCCTCCCACCTCCCCTCCTACGAGCTGCGGCATAACCAGGTGGAG TCCATTTTCCTGTCTGCCATTGACATGTACGGCCACCAGTTCTGCCCCGAGAACCTCAAG AAATTAATACTTTCGGAAACAACCATCTTCGACGTCCTGCCTACTTTCTTCTATCACGCA AACAAAGTCGTGTGCATGGCGTCCTTGGAGGTTTACGTGCGGAGGGGCTACATCGCCTAT GAGTTAAACAGCCTGCAGCACCGGCAGCTCCCGGACGGCACCTGCGTGGTAGAATTCCAG TTCATGCTGCCGTCCTCCCACCCAAACCGGATGACCGTGCCCATCAGCATCACCAACCCT GACCTGCTGAGGCACAGCACAGAGCTCTTCATGGACAGCGGCTTCTCCCCACTGTGCCAG CGCATGGGAGCCATGGTAGCCTTCAGGAGATTCGAGGACTTCACCAGAAATTTTGATGAA GTCATCTCTTGCTTCGCCAACGTGCCCAAAGACACCCCCCTCTTCAGCGAGGCCCGCACC TCCCTATACTCCGAGGATGACTGCAAGAGCCTCAGAGAAGAGCCCATCCACATTCTGAAT GTGTCCATCCAGTGTGCAGACCACCTGGAGGATGAGGCACTGGTGCCGATTTTACGGACA TTCGTACAGTCCAAGAAAAATATCCTTGTGGATTATGGACTCCGACGAATCACATTCTTG ATTGCCCAAGAGAAAGAATTTCCCAAGTTTTTCACATTCAGAGCAAGAGATGAGTTTGCA GAAGATCGCATTTACCGTCACTTGGAACCTGCCCTGGCCTTCCAGCTGGAACTTAACCGG ATGCGTAACTTCGATCTGACCGCCGTGCCCTGTGCCAACCACAAGATGCACCTTTACCTG GGTGCTGCCAAGGTGAAGGAAGGTGTGGAAGTGACGGACCATAGGTTCTTCATCCGCGCC ATCATCAGGCACTCTGACCTGATCACAAAGGAAGCCTCCTTCGAATACCTGCAGAACGAG GGTGAGCGGCTGCTCCTGGAGGCCATGGACGAGCTGGAGGTGGCGTTCAATAACACCAGC GTGCGCACCGACTGCAACCACATCTTCCTCAACTTCGTGCCCACTGTCATCATGGACCCC TTCAAGATCGAGGAGTCCGTGCGCTACATGGTTATGCGCTACGGCAGCCGGCTGTGGAAA CTCCGTGTGCTACAGGCTGAGGTCAAGATCAACATCCGCCAGACCACCACCGGCAGTGCC GTTCCCATCCGCCTGTTCATCACCAATGAGTCGGGCTACTACCTGGACATCAGCCTCTAC AAAGAAGTGACTGACTCCAGATCTGGAAATATCATGTTTCACTCCTTCGGCAACAAGCAA GGGCCCCAGCACGGGATGCTGATCAATACTCCCTACGTCACCAAGGATCTGCTCCAGGCC AAGCGATTCCAGGCCCAGACCCTGGGAACCACCTACATCTATGACTTCCCGGAAATGTTC AGGCAGGCTCTCTTTAAACTGTGGGGCTCCCCAGACAAGTATCCCAAAGACATCCTGACA TACACTGAATTAGTGTTGGACTCTCAGGGCCAGCTGGTGGAGATGAACCGACTTCCTGGT GGAAATGAGGTGGGCATGGTGGCCTTCAAAATGAGGTTTAAGACCCAGGAGTACCCGGAA GGACGGGATGTGATCGTCATCGGCAATGACATCACCTTTCGCATTGGATCCTTTGGCCCT GGAGAGGACCTTCTGTACCTGCGGGCATCCGAGATGGCCCGGGCAGAGGGCATTCCCAAA ATTTACGTGGCAGCCAACAGTGGCGCCCGTATTGGCATGGCAGAGGAGATCAAACACATG TTCCACGTGGCTTGGGTGGACCCAGAAGACCCCCACAAAGGATTTAAATACCTGTACCTG ACTCCCCAAGACTACACCAGAATCAGCTCCCTGAACTCCGTCCACTGTAAACACATCGAG GAAGGAGGAGAGTCCAGATACATGATCACGGATATCATCGGGAAGGATGATGGCTTGGGC GTGGAGAATCTGAGGGGCTCAGGCATGATTGCTGGGGAGTCCTCTCTGGCTTACGAAGAG ATCGTCACCATTAGCTTGGTGACCTGCCGAGCCATTGGGATTGGGGCCTACTTGGTGAGG CTGGGCCAGCGAGTGATCCAGGTGGAGAATTCCCACATCATCCTCACAGGAGCAAGTGCT CTCAACAAGGTCCTGGGAAGAGAGGTCTACACATCCAACAACCAGCTGGGTGGCGTTCAG ATCATGCATTACAATGGTGTCTCCCACATCACCGTGCCAGATGACTTTGAGGGGGTTTAT ACCATCCTGGAGTGGCTGTCCTATATGCCAAAGGATAATCACAGCCCTGTCCCTATCATC ACACCCACTGACCCCATTGACAGAGAAATTGAATTCCTCCCATCCAGAGCTCCCTACGAC CCCCGGTGGATGCTTGCAGGAAGGCCTCACCCAACTCTGAAGGGAACGTGGCAGAGCGGA TTCTTTGACCACGGCAGTTTCAAGGAAATCATGGCACCCTGGGCGCAGACCGTGGTGACA GGACGAGCAAGGCTTGGGGGGATTCCCGTGGGAGTGATTGCTGTGGAGACACGGACTGTG GAGGTGGCAGTCCCTGCAGACCCTGCCAACCTGGATTCTGAGGCCAAGATAATTCAGCAG GCAGGACAGGTGTGGTTCCCAGACTCAGCCTACAAAACCGCCCAGGCCGTCAAGGACTTC AACCGGGAGAAGTTGCCCCTGATGATCTTTGCCAACTGGAGGGGGTTCTCCGGTGGCATG AAAGACATGTATGACCAGGTGCTGAAGTTTGGAGCCTACATCGTGGACGGCCTTAGACAA TACAAACAGCCCATCCTGATCTATATCCCGCCCTATGCGGAGCTCCGGGGAGGCTCCTGG GTGGTCATAGATGCCACCATCAACCCGCTGTGCATAGAAATGTATGCAGACAAAGAGAGC AGGGGTGGTGTTCTGGAACCAGAGGGGACAGTGGAGATTAAGTTCCGAAAGAAAGATCTG ATAAAGTCCATGAGAAGGATCGATCCAGCTTACAAGAAGCTCATGGAACAGCTAGGGGAA CCTGATCTCTCCGACAAGGACCGAAAGGACCTGGAGGGCCGGCTAAAGGCTCGCGAGGAC CTGCTGCTCCCCATCTACCACCAGGTGGCGGTGCAGTTCGCCGACTTCCATGACACACCC GGCCGGATGCTGGAGAAGGGCGTCATATCTGACATCCTGGAGTGGAAGACCGCACGCACC TTCCTGTATTGGCGTCTGCGCCGCCTCCTCCTGGAGGACCAGGTCAAGCAGGAGATCCTG CAGGCCAGCGGGGAGCTGAGTCACGTGCATATCCAGTCCATGCTGCGTCGCTGGTTCGTG GAGACGGAGGGGGCTGTCAAGGCCTACTTGTGGGACAACAACCAGGTGGTTGTGCAGTGG CTGGAACAGCACTGGCAGGCAGGGGATGGCCCGCGCTCCACCATCCGTGAGAACATCACG TACCTGAAGCACGACTCTGTCCTCAAGACCATCCGAGGCCTGGTTGAAGAAAACCCCGAG GTGGCCGTGGACTGTGTGATATACCTGAGCCAGCACATCAGCCCAGCTGAGCGGGCGCAG GTCGTTCACCTGCTGTCTACCATGGACAGCCCGGCCTCCACCGTTTAAACGAATTCGAGC TCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGATCCGGCTGCTAA CAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATAACTAGCATAACC CCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGGAGGAACTATATCCGG TTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCATGTAAGCCCACTGCAAGC TACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCAGTAGCTGACATT CATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTGTTCCGCTTCCTTTAGCA GCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAAGAATTGCCAGCTGGGGCG CCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATGGCTTTCTTGCCGCCAAGG ATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGATGACGGTCGTTTCGCATG CTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGGGTGGAGAGGCTATTCGGC TATGACTGGGCACAACAGACAATCGGCTGCTCTGATGCCGCCGTGTTCCGGCTGTCAGCG CAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGTGCCCTGAATGAACTGCAG GACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTTCCTTGCGCAGCTGTGCTC GACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGCGAAGTGCCGGGGCAGGAT CTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATCATGGCTGATGCAATGCGG CGGCTGCATACGCTTGATCCGGCTACCTGCCCATTCGACCACCAAGCGAAACATCGCATC GAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAGGATGATCTGGACGAAGAG CATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAGGCGCGTATGCCGGATGGT GAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAATATCATGGTGGAAAATGGC CGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCGGACCGCTATCAGGACATA GCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAATGGGCTGACCGCTTCCTC GTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCCTTCTATCGCCTTCTTGAC GAGTTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACCAAGCGACGCCCAACCGGT ATCAGCTCACTCAAAGGCGGTAATACGGTTATCCACAGAATCAGGGGATAACGCAGGAAA GAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGCCGCGTTGCTGGC GTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCAGAG GTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGT GCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGG AAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCGTTCG CTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGG TAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACTGGCAGCAGCCAC TGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGTTCTTGAAGTGGTG GCCTAACTACGGCTACACTAGAAGGACAGTATTTGGTATCTGCGCTCTGCTGAAGCCAGT TACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTAGCGG TGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAAAGGATTTCAAGAAGATCC TTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAGGGATTTT GGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTATAGTCCGGAAATACAGG AACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAATGGCAGCTTCAGT GGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTATTCATACGGTTAA AATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCATTTTTACCTGTCT GCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAGGGATTATGGTAAA TCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACTCCGGCCACGATGC GTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACAGATTAAATCAGAACGCAGAAG CGGTCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGTGGTCCCACCTGACCCCAT GCCGAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGTGGGGTCTCCCCATGCGAG AGTAGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGTCGAAAGACTGGGCCTTTC GTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGACAAATCCGCCGGGAGCGG ATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAGGACGCCCGCCATAAACTG CCAGGCATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCCTTTTTGCGTTTCTACAAA CTCTTTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCAT
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