-
SpecieshumanProduct IDFXC05989Cloning SiteSgfI-PmeIGeneKIBB8622SymbolVAV2
Alias : VAV-2Descriptionvav 2 guanine nucleotide exchange factor, transcript variant 2Original Clone IDcp01300
Length: 2517 bp
Restriction map A
Restriction map B
Genomic Structure
-
Length: 839 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS6979.1 5e-199 100.0 VAV2 CCDS48053.1 7.5e-137 95.6 VAV2 CCDS12174.1 7.5e-95 52.0 VAV1 CCDS785.1 2.9e-76 54.1 VAV3 CCDS59341.1 2e-74 50.8 VAV1
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ]
Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR000980 663 677 PR00401 SH2 motif IPR000980 682 692 PR00401 SH2 motif IPR000980 706 716 PR00401 SH2 motif IPR000980 726 740 PR00401 SH2 motif IPR001452 780 790 PR00452 Src homology-3 domain IPR001452 794 809 PR00452 Src homology-3 domain IPR001452 813 822 PR00452 Src homology-3 domain IPR001452 824 836 PR00452 Src homology-3 domain HMMPfam IPR022613 19 103 PF11971 Calmodulin-regulated spectrin-associated protein IPR000219 197 370 PF00621 Dbl homology (DH) domain IPR001849 403 501 PF00169 Pleckstrin homology domain IPR002219 514 561 PF00130 Protein kinase C-like IPR011511 581 640 PF07653 Variant SH3 IPR000980 663 737 PF00017 SH2 motif IPR011511 787 835 PF07653 Variant SH3 HMMSmart IPR001715 3 115 SM00033 Calponin homology domain IPR000219 197 370 SM00325 Dbl homology (DH) domain IPR001849 401 504 SM00233 Pleckstrin homology domain IPR002219 514 562 SM00109 Protein kinase C-like IPR001452 579 641 SM00326 Src homology-3 domain IPR000980 661 743 SM00252 SH2 motif IPR001452 780 837 SM00326 Src homology-3 domain ProfileScan IPR001715 1 119 PS50021 Calponin homology domain IPR000219 193 371 PS50010 Dbl homology (DH) domain IPR001849 400 502 PS50003 Pleckstrin homology domain IPR002219 513 562 PS50081 Protein kinase C-like IPR001452 576 642 PS50002 Src homology-3 domain IPR000980 663 757 PS50001 SH2 motif IPR001452 777 838 PS50002 Src homology-3 domain
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_003362 839 600428 100.0 100.0 XP_016870601 844 600428 99.4 100.0 XP_005272270 868 600428 96.7 100.0 XP_016870599 873 600428 96.1 100.0 NP_001127870 878 600428 95.6 100.0 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB8622 Download>KIBB8622 2517 bp ATGGAGCAGTGGCGACAGTGCGGCCGCTGGCTCATCGATTGCAAGGTCCTGCCGCCCAAC CACCGGGTGGTGTGGCCCTCGGCCGTGGTCTTCGACCTGGCGCAGGCGCTGCGCGACGGG GTCCTTCTGTGCCAGCTGCTGCACAACCTCTCCCCCGGCTCCATCGACCTCAAGGACATC AACTTCCGGCCGCAGATGTCCCAGTTTCTGTGTTTGAAGAACATACGCACCTTCCTGAAA GTCTGCCACGATAAATTTGGATTAAGGAACAGCGAGCTGTTTGACCCCTTTGACCTCTTC GATGTGCGAGACTTTGGAAAGGTCATCTCCGCGGTGTCGAGGCTCTCCCTGCACAGCATC GCGCAGAACAAAGGGATCAGGCCTTTTCCCTCAGAGGAGACCACAGAGAATGACGATGAC GTCTACCGCAGCCTGGAGGAGCTGGCCGACGAGCATGACCTGGGGGAGGACATCTACGAC TGCGTCCCGTGTGAGGATGGAGGGGACGACATCTACGAGGACATCATCAAGGTGGAGGTG CAGCAGCCCATGAAAATGGGCATGACTGAAGATGACAAGAGGAACTGCTGCCTGCTGGAG ATCCAGGAGACCGAGGCCAAGTACTACCGCACCCTGGAGGACATTGAGAAGAACTACATG AGCCCCCTGCGGCTGGTGCTGAGCCCGGCGGACATGGCAGCTGTCTTCATTAACCTGGAG GACCTGATCAAGGTGCATCACAGCTTCCTGAGGGCCATCGACGTGTCCGTGATGGTGGGG GGCAGCACGCTGGCCAAGGTCTTCCTCGATTTCAAGGAAAGGCTTCTGATCTACGGGGAG TACTGCAGCCACATGGAGCACGCCCAGAACACACTGAACCAGCTCCTGGCCAGCCGGGAG GACTTCAGGCAGAAAGTCGAGGAGTGCACACTGAAGGTCCAGGATGGAAAATTTAAGCTG CAAGACCTGCTGGTGGTCCCCATGCAGAGGGTGCTCAAATACCACCTGCTCTTGAAGGAG CTTCTGAGCCATTCTGCGGAACGGCCTGAGAGGCAGCAGCTCAAAGAAGCACTGGAAGCC ATGCAGGACTTGGCGATGTACATCAATGAAGTTAAACGGGACAAGGAGACCTTGAGGAAA ATCAGCGAATTTCAGAGTTCTATAGAAAATTTGCAAGTGAAACTGGAGGAATTTGGAAGA CCAAAGATTGACGGGGAACTGAAAGTCCGGTCCATAGTCAACCACACCAAGCAGGACAGG TACTTGTTCCTGTTTGACAAGGTGGTCATCGTCTGCAAGCGGAAGGGCTACAGCTACGAG CTCAAGGAGATCATCGAGCTGCTGTTCCACAAGATGACCGACGACCCCATGAACAACAAG GACGTCAAGAAGTGGTCCTACGGCTTCTACCTAATTCACCTTCAAGGAAAGCAGGGCTTC CAGTTTTTCTGCAAAACAGAAGATATGAAGAGGAAGTGGATGGAGCAGTTTGAGATGGCC ATGTCAAACATCAAGCCAGACAAAGCCAATGCCAACCACCACAGTTTCCAGATGTACACG TTTGACAAGACCACCAACTGCAAAGCCTGCAAAATGTTCCTCAGGGGCACCTTCTACCAG GGATACATGTGTACCAAGTGTGGCGTCGGGGCACACAAGGAGTGCCTGGAAGTGATACCT CCCTGCAAGTTCACTTCTCCTGCAGATCTGGACGCCTCCGGAGCGGGACCAGGTCCCAAG ATGGTGGCCATGCAGAATTACCATGGCAACCCAGCCCCTCCCGGGAAGCCTGTGCTGACC TTCCAGACGGGCGACGTGCTTGAGCTGCTGAGGGGCGACCCTGAGTCTCCGTGGTGGGAG GGTCGTCTGGTACAAACCAGGAAGTCAGGGTATTTCCCCAGCTCATCTGTGAAGCCCTGC CCTGTGGATGGAAGGCCGCCCATCAGCCGGCCGCCATCCCGGGAGATCGACTACACTGCA TACCCCTGGTTTGCAGGTAACATGGAGAGGCAGCAGACGGACAACCTGCTCAAGTCCCAC GCCAGCGGGACCTACCTGATCAGGGAGCGGCCTGCCGAGGCTGAGCGCTTTGCAATAAGC ATCAAGTTCAATGATGAGGTGAAGCACATCAAGGTGGTGGAGAAGGACAACTGGATCCAC ATCACAGAGGCCAAGAAATTCGACAGCCTCCTGGAGTTGGTGGAGTACTACCAGTGCCAC TCACTGAAGGAGAGCTTCAAGCAGCTGGACACCACACTCAAGTACCCCTACAAGTCCCGG GAACGTTCGGCCTCCAGGGCCTCCAGCCGGTCCCCAGTGTTCACGCCCCGCGTCATCGGC ACAGCTGTGGCCAGGTATAACTTTGCCGCCCGAGATATGAGGGAGCTTTCGCTGCGGGAG GGTGACGTGGTGAGGATCTACAGCCGCATCGGCGGAGACCAGGGCTGGTGGAAGGGCGAG ACCAACGGACGGATTGGCTGGTTTCCTTCAACGTACGTAGAAGAGGAGGGCATCCAG
Cloned ORF protein sequence for pF1KB8622 Download>KIBB8622 839 aa MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDI NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHSI AQNKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDGGDDIYEDIIKVEV QQPMKMGMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPADMAAVFINLE DLIKVHHSFLRAIDVSVMVGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASRE DFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQLKEALEA MQDLAMYINEVKRDKETLRKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDR YLFLFDKVVIVCKRKGYSYELKEIIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGKQGF QFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQ GYMCTKCGVGAHKECLEVIPPCKFTSPADLDASGAGPGPKMVAMQNYHGNPAPPGKPVLT FQTGDVLELLRGDPESPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPPSREIDYTA YPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIH ITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERSASRASSRSPVFTPRVIG TAVARYNFAARDMRELSLREGDVVRIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGIQ
Nucleotide Sequence (with vector) for pF1KB8622 Download>pF1KB8622 5630 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGGAGCAGTGG CGACAGTGCGGCCGCTGGCTCATCGATTGCAAGGTCCTGCCGCCCAACCACCGGGTGGTG TGGCCCTCGGCCGTGGTCTTCGACCTGGCGCAGGCGCTGCGCGACGGGGTCCTTCTGTGC CAGCTGCTGCACAACCTCTCCCCCGGCTCCATCGACCTCAAGGACATCAACTTCCGGCCG CAGATGTCCCAGTTTCTGTGTTTGAAGAACATACGCACCTTCCTGAAAGTCTGCCACGAT AAATTTGGATTAAGGAACAGCGAGCTGTTTGACCCCTTTGACCTCTTCGATGTGCGAGAC TTTGGAAAGGTCATCTCCGCGGTGTCGAGGCTCTCCCTGCACAGCATCGCGCAGAACAAA GGGATCAGGCCTTTTCCCTCAGAGGAGACCACAGAGAATGACGATGACGTCTACCGCAGC CTGGAGGAGCTGGCCGACGAGCATGACCTGGGGGAGGACATCTACGACTGCGTCCCGTGT GAGGATGGAGGGGACGACATCTACGAGGACATCATCAAGGTGGAGGTGCAGCAGCCCATG AAAATGGGCATGACTGAAGATGACAAGAGGAACTGCTGCCTGCTGGAGATCCAGGAGACC GAGGCCAAGTACTACCGCACCCTGGAGGACATTGAGAAGAACTACATGAGCCCCCTGCGG CTGGTGCTGAGCCCGGCGGACATGGCAGCTGTCTTCATTAACCTGGAGGACCTGATCAAG GTGCATCACAGCTTCCTGAGGGCCATCGACGTGTCCGTGATGGTGGGGGGCAGCACGCTG GCCAAGGTCTTCCTCGATTTCAAGGAAAGGCTTCTGATCTACGGGGAGTACTGCAGCCAC ATGGAGCACGCCCAGAACACACTGAACCAGCTCCTGGCCAGCCGGGAGGACTTCAGGCAG AAAGTCGAGGAGTGCACACTGAAGGTCCAGGATGGAAAATTTAAGCTGCAAGACCTGCTG GTGGTCCCCATGCAGAGGGTGCTCAAATACCACCTGCTCTTGAAGGAGCTTCTGAGCCAT TCTGCGGAACGGCCTGAGAGGCAGCAGCTCAAAGAAGCACTGGAAGCCATGCAGGACTTG GCGATGTACATCAATGAAGTTAAACGGGACAAGGAGACCTTGAGGAAAATCAGCGAATTT CAGAGTTCTATAGAAAATTTGCAAGTGAAACTGGAGGAATTTGGAAGACCAAAGATTGAC GGGGAACTGAAAGTCCGGTCCATAGTCAACCACACCAAGCAGGACAGGTACTTGTTCCTG TTTGACAAGGTGGTCATCGTCTGCAAGCGGAAGGGCTACAGCTACGAGCTCAAGGAGATC ATCGAGCTGCTGTTCCACAAGATGACCGACGACCCCATGAACAACAAGGACGTCAAGAAG TGGTCCTACGGCTTCTACCTAATTCACCTTCAAGGAAAGCAGGGCTTCCAGTTTTTCTGC AAAACAGAAGATATGAAGAGGAAGTGGATGGAGCAGTTTGAGATGGCCATGTCAAACATC AAGCCAGACAAAGCCAATGCCAACCACCACAGTTTCCAGATGTACACGTTTGACAAGACC ACCAACTGCAAAGCCTGCAAAATGTTCCTCAGGGGCACCTTCTACCAGGGATACATGTGT ACCAAGTGTGGCGTCGGGGCACACAAGGAGTGCCTGGAAGTGATACCTCCCTGCAAGTTC ACTTCTCCTGCAGATCTGGACGCCTCCGGAGCGGGACCAGGTCCCAAGATGGTGGCCATG CAGAATTACCATGGCAACCCAGCCCCTCCCGGGAAGCCTGTGCTGACCTTCCAGACGGGC GACGTGCTTGAGCTGCTGAGGGGCGACCCTGAGTCTCCGTGGTGGGAGGGTCGTCTGGTA CAAACCAGGAAGTCAGGGTATTTCCCCAGCTCATCTGTGAAGCCCTGCCCTGTGGATGGA AGGCCGCCCATCAGCCGGCCGCCATCCCGGGAGATCGACTACACTGCATACCCCTGGTTT GCAGGTAACATGGAGAGGCAGCAGACGGACAACCTGCTCAAGTCCCACGCCAGCGGGACC TACCTGATCAGGGAGCGGCCTGCCGAGGCTGAGCGCTTTGCAATAAGCATCAAGTTCAAT GATGAGGTGAAGCACATCAAGGTGGTGGAGAAGGACAACTGGATCCACATCACAGAGGCC AAGAAATTCGACAGCCTCCTGGAGTTGGTGGAGTACTACCAGTGCCACTCACTGAAGGAG AGCTTCAAGCAGCTGGACACCACACTCAAGTACCCCTACAAGTCCCGGGAACGTTCGGCC TCCAGGGCCTCCAGCCGGTCCCCAGTGTTCACGCCCCGCGTCATCGGCACAGCTGTGGCC AGGTATAACTTTGCCGCCCGAGATATGAGGGAGCTTTCGCTGCGGGAGGGTGACGTGGTG AGGATCTACAGCCGCATCGGCGGAGACCAGGGCTGGTGGAAGGGCGAGACCAACGGACGG ATTGGCTGGTTTCCTTCAACGTACGTAGAAGAGGAGGGCATCCAGGTTTAAACGAATTCG AGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGATCCGGCTGC TAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATAACTAGCATA ACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGGAGGAACTATATC CGGTTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCATGTAAGCCCACTGCA AGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCAGTAGCTGAC ATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTGTTCCGCTTCCTTTA GCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAAGAATTGCCAGCTGGG GCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATGGCTTTCTTGCCGCCA AGGATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGATGACGGTCGTTTCGC ATGCTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGGGTGGAGAGGCTATTC GGCTATGACTGGGCACAACAGACAATCGGCTGCTCTGATGCCGCCGTGTTCCGGCTGTCA GCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGTGCCCTGAATGAACTG CAGGACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTTCCTTGCGCAGCTGTG CTCGACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGCGAAGTGCCGGGGCAG GATCTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATCATGGCTGATGCAATG CGGCGGCTGCATACGCTTGATCCGGCTACCTGCCCATTCGACCACCAAGCGAAACATCGC ATCGAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAGGATGATCTGGACGAA GAGCATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAGGCGCGTATGCCGGAT GGTGAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAATATCATGGTGGAAAAT GGCCGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCGGACCGCTATCAGGAC ATAGCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAATGGGCTGACCGCTTC CTCGTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCCTTCTATCGCCTTCTT GACGAGTTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACCAAGCGACGCCCAACC GGTATCAGCTCACTCAAAGGCGGTAATACGGTTATCCACAGAATCAGGGGATAACGCAGG AAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGCCGCGTTGCT GGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCA GAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCT CGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTC GGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCGT TCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATC CGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACTGGCAGCAGC CACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGTTCTTGAAGTG GTGGCCTAACTACGGCTACACTAGAAGGACAGTATTTGGTATCTGCGCTCTGCTGAAGCC AGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTAG CGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAAAGGATTTCAAGAAGA TCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAGGGAT TTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTATAGTCCGGAAATAC AGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAATGGCAGCTTC AGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTATTCATACGGT TAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCATTTTTACCTG TCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAGGGATTATGGT AAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACTCCGGCCACGA TGCGTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACAGATTAAATCAGAACGCAG AAGCGGTCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGTGGTCCCACCTGACCC CATGCCGAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGTGGGGTCTCCCCATGC GAGAGTAGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGTCGAAAGACTGGGCCT TTCGTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGACAAATCCGCCGGGAG CGGATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAGGACGCCCGCCATAAA CTGCCAGGCATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCCTTTTTGCGTTTCTAC AAACTCTTTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCAT
more Linker info
