Gene/Protein Characteristic Table for FHC10738

Species
human

Product ID
FHC10738

Corresponding
Flexi Clone PID

ORF Sequence
DNA sequence (3090 bp)
Protein sequence (1030 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB527333]

Gene
KIEE0065

Symbol
CDKL5
Alias : EIEE2, ISSX, STK9

Description
cyclin-dependent kinase-like 5

Original Clone ID
oc00765

Quality control data of this clone

Characterization of the cloned ORF

N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand

Features of the cloned ORF sequence

Length: 3090 bp
Restriction map A Restriction map B
Features of the protein sequence

Length: 1030 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
O76039 0 100.0 Cyclin-dependen...
Homo sapiens
EAW98940 0 99.9 cyclin-dependen...
Homo sapiens
XP_548881 0 97.8 similar to cycl...
Canis lupus fam...
XP_001491126 0 97.7 cyclin-dependen...
Equus caballus
Q3UTQ8 0 93.2 Cyclin-dependen...
Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PD000001 PF00069 SM00219 SM00220 PS50011 PS00107 PS00108 PS00501

Result of InterProScan

Search method interpro_ID From To Entry Definition
BlastProDom IPR000719 13 218 PD000001 Protein kinase
HMMPfam IPR000719 13 297 PF00069 Protein kinase
HMMSmart IPR001245 13 302 SM00219 Tyrosine protein kinase
IPR002290 13 297 SM00220 Serine/threonine protein kinase
ProfileScan IPR000719 13 297 PS50011 Protein kinase
ScanRegExp IPR000719 19 43 PS00107 Protein kinase
IPR008271 131 143 PS00108 Serine/threonine protein kinase
IPR000223 971 978 PS00501 Peptidase S26A

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_001032420 1030 300203,300672,308350,312750 100.0 100.0
NP_003150 1030 300203,300672,308350,312750 100.0 100.0
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