Gene/Protein Characteristic Table for
FHC01528
Species
human
Product ID
FHC01528
Linker Type
Cloning Site
SgfI-PmeI
Gene
KIBB5522
Description
sphingosine-1-phosphate receptor 1
Original Clone ID
ef02335
Characterization of the cloned ORF
N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand
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Length: 1146 bp
Restriction map A
Restriction map B
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Length: 382 aa
Result of homology search against nr database (
FASTA output,
Multiple alignment)
Entry Exp ID% Protein Source AAF43420 8.4e-155 100.0 G protein-coupl... Homo sapiens AAX36974 8.4e-155 100.0 endothelial dif... synthetic construct AAX29856 8.4e-155 100.0 endothelial dif... synthetic construct XP_513598 8.1e-154 99.4 endothelial dif... Pan troglodytes P21453 4.3e-153 99.2 Sphingosine 1-p... Homo sapiens
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR000987 4 19 PR00642 EDG-1 sphingosine 1-phosphate receptor IPR004061 20 32 PR01523 Sphingosine 1-phosphate receptor IPR000987 33 49 PR00642 EDG-1 sphingosine 1-phosphate receptor IPR000276 47 71 PR00237 Rhodopsin-like GPCR superfamily IPR000987 69 81 PR00642 EDG-1 sphingosine 1-phosphate receptor IPR000276 80 101 PR00237 Rhodopsin-like GPCR superfamily IPR004061 98 107 PR01523 Sphingosine 1-phosphate receptor IPR000987 108 118 PR00642 EDG-1 sphingosine 1-phosphate receptor IPR004061 118 129 PR01523 Sphingosine 1-phosphate receptor IPR000276 124 146 PR00237 Rhodopsin-like GPCR superfamily IPR000987 145 161 PR00642 EDG-1 sphingosine 1-phosphate receptor IPR000276 159 180 PR00237 Rhodopsin-like GPCR superfamily IPR004061 200 210 PR01523 Sphingosine 1-phosphate receptor IPR000276 202 225 PR00237 Rhodopsin-like GPCR superfamily IPR004061 221 230 PR01523 Sphingosine 1-phosphate receptor IPR000987 231 249 PR00642 EDG-1 sphingosine 1-phosphate receptor IPR000276 254 278 PR00237 Rhodopsin-like GPCR superfamily IPR004061 285 296 PR01523 Sphingosine 1-phosphate receptor IPR000276 293 319 PR00237 Rhodopsin-like GPCR superfamily IPR004061 314 324 PR01523 Sphingosine 1-phosphate receptor IPR000987 325 344 PR00642 EDG-1 sphingosine 1-phosphate receptor IPR000987 345 361 PR00642 EDG-1 sphingosine 1-phosphate receptor IPR000987 361 378 PR00642 EDG-1 sphingosine 1-phosphate receptor HMMPfam IPR000276 62 311 PF00001 Rhodopsin-like GPCR superfamily ProfileScan IPR000276 62 311 PS50262 Rhodopsin-like GPCR superfamily ScanRegExp IPR000276 130 146 PS00237 Rhodopsin-like GPCR superfamily
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 48 TSVVFILICCFIILENIFVLLTI 70 PRIMARY 23 2 120 REGSMFVALSASVFSLLAIAIER 142 PRIMARY 23 3 165 SACWVISLILGGLPIMGWNCISA 187 PRIMARY 23 4 205 FCTTVFTLLLLSIVILYCRIYSL 227 PRIMARY 23 5 255 LKTVIIVLSVFIACWAPLFILLL 277 PRIMARY 23 6 293 AEYFLVLAVLNSGTNPIIYTLTN 315 SECONDARY 23
Result of homology search against disease genes in OMIM database
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_001391 382 601974 100.0 100.0 NP_005217 378 601965 81.5 91.1 NP_110387 398 605146 72.1 92.7 NP_476500 364 602282 72.5 87.7 NP_001392 364 602282 72.5 87.7 Inquiries or Suggestions ?
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