Gene/Protein Characteristic Table for
FHC00522
Species
human
Product ID
FHC00522
Linker Type
Cloning Site
SgfI-PmeI
Description
Rho guanine nucleotide exchange factor (GEF) 11
Characterization of the cloned ORF
N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand
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Length: 4566 bp
Restriction map A
Restriction map B
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Length: 1522 aa
Result of homology search against nr database (
FASTA output,
Multiple alignment)
Entry Exp ID% Protein Source NP_055599 0 100.0 rho guanine nuc... Homo sapiens BAA20834 0 100.0 KIAA0380 protei... Homo sapiens EAW52893 0 99.9 Rho guanine nuc... Homo sapiens XP_001167782 0 99.5 rho guanine nuc... Pan troglodytes XP_004027051 0 99.0 rho guanine nuc... Gorilla gorilla...
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR001478 47 120 PF00595 PDZ/DHR/GLGF IPR015212 307 486 PF09128 Regulator of G protein signalling-like domain IPR000219 738 922 PF00621 DH HMMSmart IPR001478 55 123 SM00228 PDZ/DHR/GLGF IPR000342 313 432 SM00315 Regulator of G protein signalling IPR000219 738 922 SM00325 DH IPR001849 966 1081 SM00233 Pleckstrin-like ProfileScan IPR001478 47 111 PS50106 PDZ/DHR/GLGF IPR000342 313 419 PS50132 Regulator of G protein signalling IPR000219 734 923 PS50010 DH IPR001849 965 1079 PS50003 Pleckstrin-like
Result of homology search against disease genes in OMIM database
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_055599 1522 605708 100.0 100.0 NP_937879 1562 605708 97.4 100.0 NP_056128 1544 601626,604763 61.5 95.2 Inquiries or Suggestions ?
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